GMPPB (GDP-mannose pyrophosphorylase B) - Rat Genome Database
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Gene: GMPPB (GDP-mannose pyrophosphorylase B) Pan paniscus
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Symbol: GMPPB
Name: GDP-mannose pyrophosphorylase B
RGD ID: 11752066
Description: ENCODES a protein that exhibits mannose-1-phosphate guanylyltransferase activity (ortholog); INVOLVED IN GDP-mannose biosynthetic process (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2T (ortholog); congenital muscular dystrophy-dystroglycanopathy A14 (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: mannose-1-phosphate guanyltransferase beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,889,479 - 50,891,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,889,479 - 50,891,969 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,653,638 - 49,656,135 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
GMPPB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,889,479 - 50,891,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,889,479 - 50,891,969 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,653,638 - 49,656,135 (-)NCBIMhudiblu_PPA_v0panPan3
GMPPB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,716,844 - 49,723,973 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl349,716,844 - 49,723,951 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,719,916 - 49,723,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,757,349 - 49,761,384 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,733,936 - 49,736,388 (-)NCBINCBI36hg18NCBI36
Celera349,723,623 - 49,726,075 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,817,885 - 49,820,383 (-)NCBIHuRef
CHM1_1349,710,967 - 49,713,465 (-)NCBICHM1_1
Gmppb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,926,438 - 107,929,120 (+)NCBIGRCm39mm39
GRCm39 Ensembl9107,926,441 - 107,930,000 (+)Ensembl
GRCm389108,049,239 - 108,051,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,049,242 - 108,052,801 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,951,621 - 107,954,267 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,907,410 - 107,909,802 (+)NCBImm8
Celera9107,659,146 - 107,661,786 (+)NCBICelera
Cytogenetic Map9F1NCBI
Gmppb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28108,737,429 - 108,767,286 (+)NCBI
Rnor_6.0 Ensembl8116,826,680 - 116,856,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08116,826,251 - 116,856,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,180,562 - 116,210,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,317,165 - 113,346,646 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8108,042,518 - 108,071,499 (+)NCBICelera
Cytogenetic Map8q32NCBI
Gmppb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,622,605 - 1,624,900 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,622,605 - 1,624,900 (-)NCBIChiLan1.0ChiLan1.0
GMPPB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2039,550,799 - 39,553,045 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12039,550,799 - 39,553,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gmppb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365291,336,002 - 1,338,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMPPB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,246,468 - 32,253,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,246,471 - 32,253,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,425,664 - 35,432,367 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GMPPB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,116,497 - 11,118,980 (-)NCBI
ChlSab1.1 Ensembl2211,116,752 - 11,118,926 (-)Ensembl
Gmppb
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,645,768 - 3,648,157 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000041819   ⟹   ENSPPAP00000019070
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl350,889,479 - 50,891,969 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000041826   ⟹   ENSPPAP00000019076
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl350,889,479 - 50,891,969 (-)Ensembl
RefSeq Acc Id: XM_003818853   ⟹   XP_003818901
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1350,889,479 - 50,891,969 (-)NCBI
Mhudiblu_PPA_v0349,653,638 - 49,656,126 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008972257   ⟹   XP_008970505
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1350,889,479 - 50,891,969 (-)NCBI
Mhudiblu_PPA_v0349,653,638 - 49,656,135 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034956479   ⟹   XP_034812370
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,653,638 - 49,656,130 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003818901 (Get FASTA)   NCBI Sequence Viewer  
  XP_008970505 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812370 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003818901   ⟸   XM_003818853
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008970505   ⟸   XM_008972257
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034812370   ⟸   XM_034956479
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000019070   ⟸   ENSPPAT00000041819
RefSeq Acc Id: ENSPPAP00000019076   ⟸   ENSPPAT00000041826
Protein Domains
NTP_transferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032705 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000019070 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000019076 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041819 UniProtKB/TrEMBL
  ENSPPAT00000041826 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.10 UniProtKB/TrEMBL
InterPro Hexapep UniProtKB/TrEMBL
  Hexapep_transf_CS UniProtKB/TrEMBL
  NTP_transferase_dom UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
  Trimer_LpxA-like_sf UniProtKB/TrEMBL
KEGG Report pps:100986111 UniProtKB/TrEMBL
NCBI Gene GMPPB ENTREZGENE
Pfam Hexapep UniProtKB/TrEMBL
  NTP_transferase UniProtKB/TrEMBL
PROSITE HEXAPEP_TRANSFERASES UniProtKB/TrEMBL
Superfamily-SCOP SSF51161 UniProtKB/TrEMBL
  SSF53448 UniProtKB/TrEMBL
UniProt A0A2R9ANZ8_PANPA UniProtKB/TrEMBL
  A0A2R9ATG2_PANPA UniProtKB/TrEMBL