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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620238
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca2
Name: ATP binding cassette subfamily A member 2
Acc ID: CHEBI:27375
Term: vincaleukoblastine
Definition: A vinca alkaloid that has formula C46H58N4O9.
Chemical ID: MESH:D014747
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abca2decreases response to substanceISOABCA2 (Homo sapiens)6480464CTDABCA2 mRNA results in decreased susceptibility to VinblastinePMID:16928819
Abca2increases expressionISOABCA2 (Homo sapiens)6480464CTDVinblastine results in increased expression of ABCA2 mRNAPMID:16928819
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