Naca (nascent polypeptide associated complex subunit alpha) - Rat Genome Database

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Gene: Naca (nascent polypeptide associated complex subunit alpha) Rattus norvegicus
Analyze
Symbol: Naca
Name: nascent polypeptide associated complex subunit alpha
RGD ID: 1308642
Description: Predicted to enable TBP-class protein binding activity; transcription coactivator activity; and unfolded protein binding activity. Predicted to be involved in several processes, including negative regulation of protein localization to endoplasmic reticulum; negative regulation of striated muscle cell apoptotic process; and positive regulation of skeletal muscle tissue growth. Predicted to act upstream of or within myoblast migration. Predicted to be located in nucleus. Predicted to be part of nascent polypeptide-associated complex. Predicted to be active in cytoplasm. Orthologous to human NACA (nascent polypeptide associated complex subunit alpha); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC288770; nascent polypeptide-associated complex alpha subunit; nascent polypeptide-associated complex subunit alpha; nascent-polypeptide-associated complex alpha polypeptide
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27468,862 - 481,992 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7469,723 - 481,992 (+)Ensembl
Rnor_6.072,458,283 - 2,470,674 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,458,264 - 2,470,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,437,474 - 2,450,445 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,330,795 - 1,342,502 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,330,206 - 1,342,498 (+)NCBI
Celera7349,093 - 361,347 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:9488445   PMID:12477932   PMID:20458337   PMID:21071677   PMID:22206666   PMID:23376485   PMID:23662692  


Genomics

Comparative Map Data
Naca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27468,862 - 481,992 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7469,723 - 481,992 (+)Ensembl
Rnor_6.072,458,283 - 2,470,674 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,458,264 - 2,470,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,437,474 - 2,450,445 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,330,795 - 1,342,502 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,330,206 - 1,342,498 (+)NCBI
Celera7349,093 - 361,347 (+)NCBICelera
Cytogenetic Map7q11NCBI
NACA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,712,427 - 56,725,299 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1256,712,305 - 56,731,628 (-)EnsemblGRCh38hg38GRCh38
GRCh371257,106,211 - 57,119,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,392,486 - 55,405,318 (-)NCBINCBI36hg18NCBI36
Build 341255,392,486 - 55,405,318NCBI
Celera1256,760,235 - 56,773,290 (-)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1254,144,919 - 54,157,979 (-)NCBIHuRef
CHM1_11257,074,331 - 57,086,908 (-)NCBICHM1_1
Naca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,869,144 - 127,884,506 (+)NCBIGRCm39mm39
GRCm39 Ensembl10127,871,444 - 127,884,506 (+)Ensembl
GRCm3810128,035,346 - 128,048,637 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,035,575 - 128,048,637 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,472,402 - 127,485,693 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,438,522 - 127,451,582 (+)NCBImm8
Celera10130,429,964 - 130,443,255 (+)NCBICelera
Cytogenetic Map10D3NCBI
Naca
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,248,599 - 4,265,584 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,251,679 - 4,265,430 (-)NCBIChiLan1.0ChiLan1.0
NACA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11232,434,366 - 32,447,510 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,434,366 - 32,447,510 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,180,823 - 32,195,645 (+)NCBIMhudiblu_PPA_v0panPan3
NACA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110938,682 - 949,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10938,683 - 949,032 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl759,858,761 - 59,859,408 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,001,345 - 1,013,850 (-)NCBI
ROS_Cfam_1.010947,647 - 960,206 (-)NCBI
ROS_Cfam_1.0 Ensembl10947,648 - 960,206 (-)Ensembl
UMICH_Zoey_3.110924,757 - 937,259 (-)NCBI
UNSW_CanFamBas_1.0101,166,677 - 1,179,175 (-)NCBI
UU_Cfam_GSD_1.0101,291,318 - 1,303,824 (-)NCBI
Naca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,840,215 - 57,852,744 (+)NCBI
SpeTri2.0NW_0049366461,017,491 - 1,030,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NACA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1522,044,569 - 22,058,096 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,718,960 - 23,751,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238541
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,655,199 - 52,670,143 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606317,172,014 - 17,172,754 (+)NCBIVero_WHO_p1.0

Position Markers
RH138645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27477,900 - 478,033 (+)MAPPERmRatBN7.2
Rnor_6.072,466,447 - 2,466,579NCBIRnor6.0
Rnor_5.072,446,218 - 2,446,350UniSTSRnor5.0
RGSC_v3.471,338,412 - 1,338,544UniSTSRGSC3.4
Celera7357,257 - 357,389UniSTS
Cytogenetic Map7q11UniSTS
UniSTS:236920  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27480,914 - 481,676 (+)MAPPERmRatBN7.2
Rnor_6.072,469,597 - 2,470,358NCBIRnor6.0
Rnor_5.072,449,368 - 2,450,129UniSTSRnor5.0
RGSC_v3.471,341,425 - 1,342,186UniSTSRGSC3.4
Celera7360,270 - 361,031UniSTS
Cytogenetic Map7q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:131
Count of miRNA genes:101
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000003550, ENSRNOT00000075681
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003550   ⟹   ENSRNOP00000003550
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7469,723 - 481,985 (+)Ensembl
Rnor_6.0 Ensembl72,458,264 - 2,470,669 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075681   ⟹   ENSRNOP00000066181
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7470,595 - 481,992 (+)Ensembl
Rnor_6.0 Ensembl72,459,141 - 2,470,674 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085092   ⟹   ENSRNOP00000075523
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7469,747 - 481,992 (+)Ensembl
Rnor_6.0 Ensembl72,458,833 - 2,470,674 (+)Ensembl
RefSeq Acc Id: NM_001105939   ⟹   NP_001099409
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27470,287 - 481,992 (+)NCBI
Rnor_6.072,458,833 - 2,470,674 (+)NCBI
Rnor_5.072,437,474 - 2,450,445 (+)NCBI
RGSC_v3.471,330,795 - 1,342,502 (+)RGD
Celera7349,643 - 361,347 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198562   ⟹   NP_001185491
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27469,704 - 481,992 (+)NCBI
Rnor_6.072,458,283 - 2,470,674 (+)NCBI
Rnor_5.072,437,474 - 2,450,445 (+)NCBI
Celera7349,093 - 361,347 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198580   ⟹   NP_001185509
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27470,595 - 481,992 (+)NCBI
Rnor_6.072,459,141 - 2,470,674 (+)NCBI
Rnor_5.072,437,474 - 2,450,445 (+)NCBI
Celera7349,951 - 361,347 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078540   ⟹   XP_038934468
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27468,862 - 481,988 (+)NCBI
RefSeq Acc Id: XM_039078541   ⟹   XP_038934469
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27469,901 - 481,988 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001099409   ⟸   NM_001105939
- Peptide Label: isoform 1
- UniProtKB: B2RYX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185491   ⟸   NM_001198562
- Peptide Label: isoform 1
- UniProtKB: B2RYX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185509   ⟸   NM_001198580
- Peptide Label: isoform 2
- UniProtKB: M0R9L0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075523   ⟸   ENSRNOT00000085092
RefSeq Acc Id: ENSRNOP00000066181   ⟸   ENSRNOT00000075681
RefSeq Acc Id: ENSRNOP00000003550   ⟸   ENSRNOT00000003550
RefSeq Acc Id: XP_038934468   ⟸   XM_039078540
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934469   ⟸   XM_039078541
- Peptide Label: isoform X1
Protein Domains
NAC-A/B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R9L0-F1-model_v2 AlphaFold M0R9L0 1-2163 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694920
Promoter ID:EPDNEW_R5445
Type:initiation region
Name:Naca_1
Description:nascent polypeptide-associated complex alpha subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,458,310 - 2,458,370EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 2459173 2459174 G A snv SBN/Ygl (MCW), SBN/Ygl (RGD)
7 2466064 2466065 A C snv MNS/Gib (RGD), SHR/NHsd (RGD), SHRSP/Gcrc (RGD), WKY/NCrl (RGD), WKY/Gcrc (RGD), FXLE18/Stm (2020), HXB20/IpcvMcwi (2020), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LE/Stm (2019), LEXF10A/StmMcwi (2020), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WKY/NCrl (2019), WKY/N (2020), LE/Stm (RGD), COP/CrCrl (MCW & UW), WKY/N (MCW)
7 2467112 2467113 C G snv GK/Ox (RGD), GK/FarMcwi (2019)
7 2468977 2468978 A T snv SBH/Ygl (MCW), SS/JrHsdMcwi (MCW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), PVG/Seac (2019), WAG/RijCrl (2020), F344/N (2020)
7 2469368 2469369 G C snv MWF/Hsd (2019), LEXF3/Stm (2020), BUF/N (2020), WAG/RijCrl (2020)
7 2469411 2469412 G C snv COP/CrCrl (MCW & UW), ACI/EurMcwi (MCW), SS/JrHsdMcwi (MCW), BUF/N (2020), LEXF3/Stm (2020), WAG/RijCrl (2020)
7 2469641 2469642 A G snv CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), GH/OmrMcwi (MCW), ACI/EurMcwi (RGD), F344/NCrl (RGD), SBH/Ygl (RGD), SHRSP/Gcrc (RGD), SR/JrHsd (RGD), WKY/NCrl (RGD), F344/N (2020), FHH/EurMcwi (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LE/Stm (2019), LL/MavRrrcAek (2020), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHR/OlalpcvMcwi (2019), WN/N (2020)
7 2469647 2469648 C T snv WN/N (2020), MWF/Hsd (2019), SHR/OlalpcvMcwi (2019), PVG/Seac (2019), CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), SBN/Ygl (MCW), ACI/EurMcwi (RGD), F344/NCrl (RGD), SBH/Ygl (RGD), SHRSP/Gcrc (RGD), SR/JrHsd (RGD), WKY/NCrl (RGD), F344/N (2020), FHH/EurMcwi (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LE/Stm (2019), LL/MavRrrcAek (2020), M520/N (2020), MR/N (2020)
7 2470313 2470314 T A snv COP/CrCrl (MCW & UW)
7 2470330 2470331 C A snv COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW)
7 2470339 2470340 G A snv COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW)
7 2470384 2470385 G C snv GH/OmrMcwi (MCW), COP/CrCrl (MCW & UW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 2438944 2438945 G A snv SBN/Ygl (KNAW), SBN/Ygl (MCW)
7 2445368 2445369 A C snv LEC/Tj (KyushuU)
7 2445512 2445513 G C snv LEC/Tj (KyushuU), HWY/Slc (KyushuU)
7 2445835 2445836 A C snv SHR/OlaIpcv (KNAW), SHR/OlaIpcvPrin (KNAW), SHRSP/Gcrc (KNAW), WKY/Gcrc (KNAW), WKY/N (KNAW), WKY/NCrl (KNAW), WKY/NHsd (KNAW), NIG-III/Hok (KyushuU), LE/Stm (KyushuU), SHR/NHsd (KNAW), SHR/NCrlPrin (KNAW), MNS/Gib (KNAW), LE/Stm (SOLiD) (KNAW), COP/CrCrl (MCW & UW), LE/Stm (Illumina) (KNAW)
7 2446883 2446884 C G snv GK/Ox (KNAW), DOB/Oda (KyushuU)
7 2448714 2448715 C T snv NIG-III/Hok (KyushuU), SDLEF7/Barth (UDEL)
7 2448748 2448749 A T snv NIG-III/Hok (KyushuU), F344/Stm (KyushuU)
7 2449139 2449140 G C snv LE/Stm (KyushuU), HTX/Kyo (KyushuU)
7 2449182 2449183 G C snv BDIX/NemOda (KyushuU), HTX/Kyo (KyushuU), LE/Stm (KyushuU)
7 2449412 2449413 A G snv BDIX.Cg-Tal/NemOda (KyushuU), BDIX/NemOda (KyushuU), RCS/Kyo (KyushuU), BUF/MNa (KyushuU), F344/DuCrlCrlj (KyushuU)
7 2449418 2449419 C T snv BDIX.Cg-Tal/NemOda (KyushuU), BDIX/NemOda (KyushuU), RCS/Kyo (KyushuU), BUF/MNa (KyushuU), F344/DuCrlCrlj (KyushuU), F344/NSlc (KyushuU)
7 2450084 2450085 T A snv NIG-III/Hok (KyushuU)
7 2450101 2450102 C A snv NIG-III/Hok (KyushuU), SDLEF7/Barth (UDEL)
7 2450110 2450111 G A snv NIG-III/Hok (KyushuU), SDLEF7/Barth (UDEL)
7 2450155 2450156 G C snv SDLEF7/Barth (UDEL), NIG-III/Hok (KyushuU)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 1341469 1341470 A G snv ACI/EurMcwi (MCW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 478566 478567 C G snv GK/FarMcwi (2019)
7 480959 480960 A G snv SHR/OlalpcvMcwi (2019), PVG/Seac (2019), MWF/Hsd (2019), MR/N (2020), LE/Stm (2019), LEXF3/Stm (2020), LEXF2B/Stm (2019), FHH/EurMcwi (2019), F344/N (2020), WN/N (2020), M520/N (2020)
7 480965 480966 C T snv WN/N (2020), SHR/OlalpcvMcwi (2019), PVG/Seac (2019), MWF/Hsd (2019), MR/N (2020), M520/N (2020), LE/Stm (2019), LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), FHH/EurMcwi (2019), F344/N (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308642 AgrOrtholog
BioCyc Gene G2FUF-35401 BioCyc
Ensembl Genes ENSRNOG00000002632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003550 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000066181 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075523 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003550 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000075681 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000085092 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.30 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6922001 IMAGE-MGC_LOAD
InterPro EGD2/NACA UniProtKB/TrEMBL
  NAC-like_UBA UniProtKB/TrEMBL
  NAC_A/B_dom_sf UniProtKB/TrEMBL
  Nas_poly-pep-assoc_cplx_dom UniProtKB/TrEMBL
KEGG Report rno:288770 UniProtKB/TrEMBL
MGC_CLONE MGC:188929 IMAGE-MGC_LOAD
NCBI Gene 288770 ENTREZGENE
PANTHER PTHR21713 UniProtKB/TrEMBL
Pfam HYPK_UBA UniProtKB/TrEMBL
  NAC UniProtKB/TrEMBL
PhenoGen Naca PhenoGen
PIRSF NAC_alpha UniProtKB/TrEMBL
PROSITE NAC_AB UniProtKB/TrEMBL
SMART NAC UniProtKB/TrEMBL
UniProt B2RYX0 ENTREZGENE, UniProtKB/TrEMBL
  M0R9L0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-18 Naca  nascent polypeptide associated complex subunit alpha  Naca  nascent polypeptide-associated complex alpha subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Naca  nascent polypeptide-associated complex alpha subunit  Naca  nascent-polypeptide-associated complex alpha polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Naca  nascent-polypeptide-associated complex alpha polypeptide   Naca_predicted  nascent-polypeptide-associated complex alpha polypeptide (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Naca_predicted  nascent-polypeptide-associated complex alpha polypeptide (predicted)      Symbol and Name status set to approved 70820 APPROVED