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Gene: Ptges3 (prostaglandin E synthase 3) Rattus norvegicus
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Symbol: Ptges3
Name: prostaglandin E synthase 3
Description: Exhibits several functions, including Hsp90 protein binding activity; enzyme binding activity; and p53 binding activity. Involved in several processes, including negative regulation of cell death; prostaglandin biosynthetic process; and sensory perception of pain. Localizes to several cellular components, including the actin filament; neuronal cell body; and perinuclear region of cytoplasm. Orthologous to human PTGES3 (prostaglandin E synthase 3); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH ammonium chloride; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cPGES; cytosolic prostaglandin E2 synthase; hsp90 co-chaperone; LOC362809; MGC188278; progesterone receptor complex p23; prostaglandin E synthase 3 (cytosolic); prostaglandin-E synthase 3; RGD1561913; similar to Sid3177p; telomerase-binding protein p23
Orthologs:
Homo sapiens (human) : PTGES3 (prostaglandin E synthase 3)  HGNC  Alliance
Mus musculus (house mouse) : Ptges3 (prostaglandin E synthase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges3 (prostaglandin E synthase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES3 (prostaglandin E synthase 3)
Canis lupus familiaris (dog) : PTGES3 (prostaglandin E synthase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges3 (prostaglandin E synthase 3)
Sus scrofa (pig) : PTGES3 (prostaglandin E synthase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.072,479,267 - 2,497,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,459,082 - 2,476,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,351,206 - 1,368,857 (+)NCBIRGSC3.4rn4RGSC3.4
Celera7370,050 - 386,953 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ptges3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561913
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.