Ptges3 (prostaglandin E synthase 3) - Rat Genome Database

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Gene: Ptges3 (prostaglandin E synthase 3) Rattus norvegicus
Analyze
Symbol: Ptges3
Name: prostaglandin E synthase 3
RGD ID: 1561913
Description: Enables several functions, including Hsp90 protein binding activity; p53 binding activity; and prostaglandin-E synthase activity. Involved in several processes, including negative regulation of cell death; prostaglandin biosynthetic process; and sensory perception of pain. Located in several cellular components, including actin filament; neuronal cell body; and perinuclear region of cytoplasm. Part of protein-containing complex. Orthologous to human PTGES3 (prostaglandin E synthase 3); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cPGES; cytosolic prostaglandin E2 synthase; hsp90 co-chaperone; LOC362809; MGC188278; progesterone receptor complex p23; prostaglandin E synthase 3 (cytosolic); prostaglandin-E synthase 3; RGD1561913; similar to Sid3177p; telomerase-binding protein p23
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27490,698 - 507,759 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7490,656 - 508,084 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,248,927 - 3,266,205 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.075,124,939 - 5,142,219 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.075,426,505 - 5,443,663 (+)NCBIRnor_WKY
Rnor_6.072,479,267 - 2,497,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,479,311 - 2,497,013 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,459,082 - 2,476,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,351,206 - 1,368,857 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7370,050 - 386,953 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Endoplasmic reticulum stress-induced cell death in dopaminergic cells: effect of resveratrol. Chinta SJ, etal., J Mol Neurosci. 2009 Sep;39(1-2):157-68. Epub 2009 Jan 15.
2. Microsomal prostaglandin E synthase-1 is a major terminal synthase that is selectively up-regulated during cyclooxygenase-2-dependent prostaglandin E2 production in the rat adjuvant-induced arthritis model. Claveau D, etal., J Immunol. 2003 May 1;170(9):4738-44.
3. Immunofluorescence localization of the 90-kDa heat-shock protein to cytoskeleton. Czar MJ, etal., Eur J Cell Biol. 1996 Aug;70(4):322-30.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Prostanoids as regulators of innate and adaptive immunity. Hirata T and Narumiya S, Adv Immunol. 2012;116:143-74. doi: 10.1016/B978-0-12-394300-2.00005-3.
6. Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats. Hofacker A, etal., J Neurosci. 2005 Sep 28;25(39):9005-9.
7. Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn. Majed BH and Khalil RA, Pharmacol Rev. 2012 Jul;64(3):540-82. doi: 10.1124/pr.111.004770. Epub 2012 Jun 7.
8. Cytosolic prostaglandin E2 synthase/p23 but not apoptosis-linked gene 2 is downregulated in human atherosclerotic plaques. Martinet W, etal., Cardiovasc Res. 2004 Feb 1;61(2):360-1.
9. The terminal prostaglandin synthases mPGES-1, mPGES-2, and cPGES are all overexpressed in human gliomas. Mattila S, etal., Neuropathology. 2009 Apr;29(2):156-65.
10. Involvement of the constitutive prostaglandin E synthase cPGES/p23 in expression of an initial prostaglandin E2 inactivating enzyme, 15-PGDH. Nakatani Y, etal., Prostaglandins Other Lipid Mediat. 2011 Apr;94(3-4):112-7. Epub 2011 Feb 17.
11. Chaperoning of glucocorticoid receptors. Pratt WB, etal., Handb Exp Pharmacol. 2006;(172):111-38.
12. Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth. Quinta HR, etal., J Neurochem. 2010 Nov;115(3):716-34. doi: 10.1111/j.1471-4159.2010.06970.x. Epub 2010 Sep 28.
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. Simpson NE, etal., Cancer Res. 2010 Nov 1;70(21):8446-56. Epub 2010 Sep 16.
16. Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions. Smith DF and Toft DO, Mol Endocrinol. 2008 Oct;22(10):2229-40. Epub 2008 May 1.
17. Regulation of cytosolic prostaglandin E2 synthase by 90-kDa heat shock protein. Tanioka T, etal., Biochem Biophys Res Commun. 2003 Apr 18;303(4):1018-23.
18. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. Tanioka T, etal., J Biol Chem. 2000 Oct 20;275(42):32775-82.
19. Intracellular-specific colocalization of prostaglandin E2 synthases and cyclooxygenases in the brain. Vazquez-Tello A, etal., Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1155-63. Epub 2004 Jul 29.
20. The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent. Whitesell L, etal., Mol Cell Biol. 1998 Mar;18(3):1517-24.
21. Interactions of the mineralocorticoid receptor--within and without. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
Additional References at PubMed
PMID:10197982   PMID:10543959   PMID:10811660   PMID:12077419   PMID:12135483   PMID:12477932   PMID:12853476   PMID:17438133   PMID:19740745   PMID:19751963   PMID:21630459   PMID:22871113  
PMID:23376485   PMID:29093345   PMID:29127155  


Genomics

Comparative Map Data
Ptges3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27490,698 - 507,759 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7490,656 - 508,084 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,248,927 - 3,266,205 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.075,124,939 - 5,142,219 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.075,426,505 - 5,443,663 (+)NCBIRnor_WKY
Rnor_6.072,479,267 - 2,497,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,479,311 - 2,497,013 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,459,082 - 2,476,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,351,206 - 1,368,857 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7370,050 - 386,953 (+)NCBICelera
Cytogenetic Map7q11NCBI
PTGES3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,663,349 - 56,688,284 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1256,663,341 - 56,688,408 (-)EnsemblGRCh38hg38GRCh38
GRCh371257,057,133 - 57,082,068 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,343,649 - 55,368,156 (-)NCBINCBI36Build 36hg18NCBI36
Celera1256,709,596 - 56,735,126 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,096,410 - 54,121,394 (-)NCBIHuRef
CHM1_11257,024,664 - 57,049,890 (-)NCBICHM1_1
T2T-CHM13v2.01256,631,338 - 56,656,287 (-)NCBIT2T-CHM13v2.0
Ptges3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,894,851 - 127,913,123 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,894,823 - 127,913,141 (+)EnsemblGRCm39 Ensembl
GRCm3810128,058,982 - 128,077,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,058,954 - 128,077,272 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,496,038 - 127,514,310 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,461,931 - 127,480,203 (+)NCBIMGSCv36mm8
Celera10130,453,617 - 130,471,989 (+)NCBICelera
Cytogenetic Map10D3NCBI
Ptges3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,203,076 - 4,209,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554584,203,075 - 4,209,967 (-)NCBIChiLan1.0ChiLan1.0
PTGES3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11232,475,989 - 32,503,181 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,476,835 - 32,503,181 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,221,908 - 32,247,228 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PTGES3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110885,744 - 903,814 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10870,392 - 909,161 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10948,938 - 967,016 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010895,074 - 912,966 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10879,724 - 919,087 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110871,924 - 889,991 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,115,085 - 1,132,100 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,238,847 - 1,256,742 (-)NCBIUU_Cfam_GSD_1.0
Ptges3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,879,818 - 57,900,555 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936646969,674 - 990,532 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGES3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,000,341 - 22,021,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,000,335 - 22,022,830 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,674,707 - 23,696,337 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTGES3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,609,460 - 52,634,490 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037193,344,739 - 193,370,949 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptges3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,360,041 - 11,395,390 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,360,056 - 11,392,911 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptges3
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:98
Count of miRNA genes:82
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000003787
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat

Markers in Region
RH127823  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27507,474 - 507,667 (+)MAPPERmRatBN7.2
Rnor_6.072,496,729 - 2,496,921NCBIRnor6.0
Rnor_5.072,476,116 - 2,476,308UniSTSRnor5.0
RGSC_v3.471,368,573 - 1,368,765UniSTSRGSC3.4
Celera7386,669 - 386,861UniSTS
Cytogenetic MapXq22UniSTS
Cytogenetic Map7q11UniSTS
UniSTS:234880  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23138,422,800 - 138,423,071 (-)MAPPERmRatBN7.2
mRatBN7.23138,422,800 - 138,423,071 (+)MAPPERmRatBN7.2
mRatBN7.23139,113,719 - 139,113,990 (-)MAPPERmRatBN7.2
mRatBN7.23139,113,719 - 139,113,990 (+)MAPPERmRatBN7.2
Rnor_6.03145,442,092 - 145,442,362NCBIRnor6.0
Rnor_6.03145,989,568 - 145,989,838NCBIRnor6.0
Rnor_5.03152,350,261 - 152,350,531UniSTSRnor5.0
Rnor_5.03151,809,970 - 151,810,240UniSTSRnor5.0
RGSC_v3.43140,062,377 - 140,062,647UniSTSRGSC3.4
Celera3137,871,890 - 137,872,160UniSTS
Cytogenetic Map7q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003787   ⟹   ENSRNOP00000003787
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7490,656 - 507,752 (+)Ensembl
Rnor_6.0 Ensembl72,479,311 - 2,497,013 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094676   ⟹   ENSRNOP00000082352
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7490,703 - 507,571 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097034   ⟹   ENSRNOP00000080703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7499,952 - 507,571 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097314   ⟹   ENSRNOP00000085230
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7499,595 - 508,084 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097618   ⟹   ENSRNOP00000096830
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7499,609 - 508,084 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101866   ⟹   ENSRNOP00000096607
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7491,055 - 508,084 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104676   ⟹   ENSRNOP00000096677
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7490,679 - 508,084 (+)Ensembl
RefSeq Acc Id: NM_001130989   ⟹   NP_001124461
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27490,698 - 507,759 (+)NCBI
Rnor_6.072,479,311 - 2,497,013 (+)NCBI
Rnor_5.072,459,082 - 2,476,400 (+)NCBI
RGSC_v3.471,351,206 - 1,368,857 (+)RGD
Celera7370,050 - 386,953 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001124461 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66579 (Get FASTA)   NCBI Sequence Viewer  
  EDL84891 (Get FASTA)   NCBI Sequence Viewer  
  P83868 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001124461   ⟸   NM_001130989
- UniProtKB: P83868 (UniProtKB/Swiss-Prot),   B2GV92 (UniProtKB/TrEMBL),   R9PXR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003787   ⟸   ENSRNOT00000003787
RefSeq Acc Id: ENSRNOP00000082352   ⟸   ENSRNOT00000094676
RefSeq Acc Id: ENSRNOP00000096677   ⟸   ENSRNOT00000104676
RefSeq Acc Id: ENSRNOP00000085230   ⟸   ENSRNOT00000097314
RefSeq Acc Id: ENSRNOP00000096607   ⟸   ENSRNOT00000101866
RefSeq Acc Id: ENSRNOP00000096830   ⟸   ENSRNOT00000097618
RefSeq Acc Id: ENSRNOP00000080703   ⟸   ENSRNOT00000097034
Protein Domains
CS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P83868-F1-model_v2 AlphaFold P83868 1-160 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694921
Promoter ID:EPDNEW_R5446
Type:initiation region
Name:Ptges3_1
Description:prostaglandin E synthase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,479,326 - 2,479,386EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561913 AgrOrtholog
BioCyc Gene G2FUF-35400 BioCyc
BioCyc Pathway PWY66-374 [C20 prostanoid biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000002642 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003787 ENTREZGENE
  ENSRNOP00000003787.8 UniProtKB/TrEMBL
  ENSRNOP00000080703.1 UniProtKB/TrEMBL
  ENSRNOP00000082352.1 UniProtKB/TrEMBL
  ENSRNOP00000085230.1 UniProtKB/TrEMBL
  ENSRNOP00000096607.1 UniProtKB/TrEMBL
  ENSRNOP00000096677.1 UniProtKB/TrEMBL
  ENSRNOP00000096830.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003787 ENTREZGENE
  ENSRNOT00000003787.8 UniProtKB/TrEMBL
  ENSRNOT00000094676.1 UniProtKB/TrEMBL
  ENSRNOT00000097034.1 UniProtKB/TrEMBL
  ENSRNOT00000097314.1 UniProtKB/TrEMBL
  ENSRNOT00000097618.1 UniProtKB/TrEMBL
  ENSRNOT00000101866.1 UniProtKB/TrEMBL
  ENSRNOT00000104676.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p23-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362809 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 362809 ENTREZGENE
PANTHER PTHR22932 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF04969 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptges3 PhenoGen
PROSITE PS51203 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49764 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQW8_RAT UniProtKB/TrEMBL
  A0A8I5ZTE4_RAT UniProtKB/TrEMBL
  A0A8I5ZZQ2_RAT UniProtKB/TrEMBL
  A0A8I6AQE2_RAT UniProtKB/TrEMBL
  A0A8I6AQZ3_RAT UniProtKB/TrEMBL
  A0A8I6ATR8_RAT UniProtKB/TrEMBL
  A0A8L2Q1B4_RAT UniProtKB/TrEMBL
  B2GV92 ENTREZGENE, UniProtKB/TrEMBL
  P83868 ENTREZGENE
  R9PXR7 ENTREZGENE
  TEBP_RAT UniProtKB/Swiss-Prot
UniProt Secondary R9PXR7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Ptges3  prostaglandin E synthase 3  Ptges3  prostaglandin E synthase 3 (cytosolic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ptges3  prostaglandin E synthase 3 (cytosolic)   Ptges3_predicted  prostaglandin E synthase 3 (cytosolic) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ptges3_predicted  prostaglandin E synthase 3 (cytosolic) (predicted)  RGD1561913_predicted  similar to Sid3177p (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1561913_predicted  similar to Sid3177p (predicted)  LOC362809  similar to Sid3177p  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC362809  similar to Sid3177p      Symbol and Name status set to provisional 70820 PROVISIONAL