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Gene: Ptges3 (prostaglandin E synthase 3) Mus musculus
Symbol: Ptges3
Name: prostaglandin E synthase 3
RGD ID: 1620858
Description: Exhibits DNA polymerase binding activity. Involved in several processes, including cellular macromolecule biosynthetic process; glucocorticoid receptor signaling pathway; and positive regulation of telomerase activity. Predicted to localize to several cellular components, including actin filament; neuronal cell body; and telomerase holoenzyme complex. Is expressed in several structures, including liver and skin. Orthologous to human PTGES3 (prostaglandin E synthase 3); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: 5730442A20Rik; cPG; cPGES; cytosolic prostaglandin E2 synthase; hsp90 co-chaperone; p23; p23 cochaperone; progesterone receptor complex p23; prostaglandin E synthase 3 (cytosolic); Ptg; Ptges; sid 3177; sid31; sid3177; Teb; Tebp; telomerase binding protein, p23; telomerase-binding protein p23
Homo sapiens (human) : PTGES3 (prostaglandin E synthase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptges3 (prostaglandin E synthase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges3 (prostaglandin E synthase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES3 (prostaglandin E synthase 3)
Canis lupus familiaris (dog) : PTGES3 (prostaglandin E synthase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges3 (prostaglandin E synthase 3)
Sus scrofa (pig) : PTGES3 (prostaglandin E synthase 3)
Chlorocebus sabaeus (African green monkey) : PTGES3 (prostaglandin E synthase 3)
Heterocephalus glaber (naked mole-rat) : Ptges3 (prostaglandin E synthase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl10128,058,954 - 128,077,272 (+)EnsemblGRCm38mm10GRCm38
GRCm3810128,058,982 - 128,077,254 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710127,496,038 - 127,514,310 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,461,931 - 127,480,203 (+)NCBImm8
Celera10130,453,617 - 130,471,989 (+)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ptges3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1620858
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.