Nisch (nischarin) - Rat Genome Database

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Gene: Nisch (nischarin) Rattus norvegicus
Analyze
Symbol: Nisch
Name: nischarin
RGD ID: 1306950
Description: Predicted to enable several functions, including alpha-tubulin binding activity; dynein heavy chain binding activity; and integrin binding activity. Involved in several processes, including glucose metabolic process; norepinephrine secretion; and regulation of GABAergic synaptic transmission. Predicted to be located in several cellular components, including intercellular bridge; microtubule cytoskeleton; and nucleoplasm. Predicted to be active in cytoplasm. Used to study hypertension. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human NISCH (nischarin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: I-1; I-1 receptor candidate protein; I1R; imidazoline receptor 1; imidazoline receptor I-1; imidazoline-1 receptor; IR1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,370,809 - 6,407,104 (-)NCBIGRCr8
mRatBN7.2166,364,370 - 6,400,675 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,364,374 - 6,400,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,388,854 - 6,412,881 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,534,079 - 7,558,106 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,395,765 - 6,419,885 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,254,372 - 7,290,670 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,254,974 - 7,290,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,182,941 - 7,219,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,601,521 - 6,637,734 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,602,120 - 6,637,709 (-)NCBI
Celera168,788,272 - 8,824,554 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-methoxyethanol  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP,ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
DPCPX  (EXP)
ethanol  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
FR900359  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
motexafin gadolinium  (ISO)
Moxonidine  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (ISO)
ochratoxin A  (EXP)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phosgene  (ISO)
picoxystrobin  (ISO)
pinostrobin  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
propiconazole  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
thioacetamide  (EXP)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zinc acetate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Augmentation of moxonidine-induced increase in ANP release by atrial hypertrophy. Cao C, etal., Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H150-6. Epub 2004 Feb 19.
2. Imidazoline receptors in the heart: characterization, distribution, and regulation. El-Ayoubi R, etal., J Cardiovasc Pharmacol. 2002 Jun;39(6):875-83.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. The role of I(1)-imidazoline receptors and alpha(2)-adrenergic receptors in the modulation of glucose and lipid metabolism in the SHROB model of metabolic syndrome X. Koletsky RJ, etal., Ann N Y Acad Sci. 2003 Dec;1009:251-61.
5. Norepinephrine release is reduced by I(1)-receptors in addition to alpha(2)-adrenoceptors. Raasch W, etal., Ann N Y Acad Sci. 2003 Dec;1009:270-3.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Presynaptic I1-imidazoline receptors reduce GABAergic synaptic transmission in striatal medium spiny neurons. Tanabe M, etal., J Neurosci. 2006 Feb 8;26(6):1795-802.
Additional References at PubMed
PMID:11121431   PMID:12477932   PMID:15028622   PMID:17940198   PMID:19034032   PMID:19946888   PMID:20394743   PMID:21228308   PMID:23166584   PMID:23342172   PMID:23386062   PMID:24064952  
PMID:26670864   PMID:33075003  


Genomics

Comparative Map Data
Nisch
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,370,809 - 6,407,104 (-)NCBIGRCr8
mRatBN7.2166,364,370 - 6,400,675 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,364,374 - 6,400,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,388,854 - 6,412,881 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,534,079 - 7,558,106 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,395,765 - 6,419,885 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,254,372 - 7,290,670 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,254,974 - 7,290,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,182,941 - 7,219,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,601,521 - 6,637,734 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,602,120 - 6,637,709 (-)NCBI
Celera168,788,272 - 8,824,554 (+)NCBICelera
Cytogenetic Map16p16NCBI
NISCH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,455,604 - 52,493,068 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,455,118 - 52,493,068 (+)EnsemblGRCh38hg38GRCh38
GRCh37352,489,620 - 52,527,084 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,464,564 - 52,502,128 (+)NCBINCBI36Build 36hg18NCBI36
Build 34352,464,671 - 52,502,125NCBI
Celera352,468,769 - 52,506,327 (+)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,552,184 - 52,589,631 (+)NCBIHuRef
CHM1_1352,441,901 - 52,479,443 (+)NCBICHM1_1
T2T-CHM13v2.0352,488,505 - 52,525,966 (+)NCBIT2T-CHM13v2.0
Nisch
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,892,885 - 30,928,783 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,892,887 - 30,938,903 (-)EnsemblGRCm39 Ensembl
GRCm381431,170,928 - 31,206,826 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,170,930 - 31,216,946 (-)EnsemblGRCm38mm10GRCm38
MGSCv371431,984,114 - 32,020,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,999,937 - 30,020,559 (-)NCBIMGSCv36mm8
Celera1427,429,490 - 27,465,449 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.09NCBI
Nisch
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,443,029 - 2,491,123 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,443,029 - 2,488,267 (+)NCBIChiLan1.0ChiLan1.0
NISCH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,450,617 - 52,488,273 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,455,389 - 52,493,045 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,397,576 - 52,435,127 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,626,176 - 53,663,128 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,626,317 - 53,662,567 (+)Ensemblpanpan1.1panPan2
NISCH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,278,660 - 37,312,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,279,282 - 37,312,636 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,260,489 - 37,294,003 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,628,115 - 37,662,575 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,628,116 - 37,662,560 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12036,992,617 - 37,026,536 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,401,248 - 37,435,163 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,679,538 - 37,719,774 (-)NCBIUU_Cfam_GSD_1.0
Nisch
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,156,942 - 170,192,753 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364733,295,515 - 3,331,324 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NISCH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,595,782 - 34,630,303 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,595,788 - 34,630,306 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,809,589 - 37,844,045 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NISCH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,821,026 - 13,860,430 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,841,352 - 13,860,498 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,039,458 - 153,078,870 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nisch
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,726,407 - 4,763,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,725,715 - 4,763,579 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nisch
162 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:69
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000036910
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1619639137Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760916039848Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16285170915884239Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat

Markers in Region
BI275177  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,376,687 - 6,376,896 (+)MAPPERmRatBN7.2
Rnor_6.0167,266,689 - 7,266,897NCBIRnor6.0
Rnor_5.0167,195,259 - 7,195,467UniSTSRnor5.0
RGSC_v3.4166,613,839 - 6,614,047UniSTSRGSC3.4
Celera168,812,039 - 8,812,247UniSTS
RH 3.4 Map1646.4UniSTS
Cytogenetic Map16p16UniSTS
BI282284  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,364,576 - 6,364,792 (+)MAPPERmRatBN7.2
Rnor_6.0167,254,579 - 7,254,794NCBIRnor6.0
Rnor_5.0167,183,148 - 7,183,363UniSTSRnor5.0
RGSC_v3.4166,601,728 - 6,601,943UniSTSRGSC3.4
Celera168,824,132 - 8,824,347UniSTS
RH 3.4 Map1643.3UniSTS
Cytogenetic Map16p16UniSTS
RH127675  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,364,535 - 6,364,745 (+)MAPPERmRatBN7.2
Rnor_6.0167,254,538 - 7,254,747NCBIRnor6.0
Rnor_5.0167,183,107 - 7,183,316UniSTSRnor5.0
RGSC_v3.4166,601,687 - 6,601,896UniSTSRGSC3.4
Celera168,824,179 - 8,824,388UniSTS
RH 3.4 Map1649.0UniSTS
Cytogenetic Map16p16UniSTS
RH143465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,369,175 - 6,369,320 (+)MAPPERmRatBN7.2
Rnor_6.0167,259,178 - 7,259,322NCBIRnor6.0
Rnor_5.0167,187,747 - 7,187,891UniSTSRnor5.0
RGSC_v3.4166,606,327 - 6,606,471UniSTSRGSC3.4
Celera168,819,604 - 8,819,748UniSTS
RH 3.4 Map1646.3UniSTS
Cytogenetic Map16p16UniSTS
BI289970  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,401,676 - 6,401,835 (+)MAPPERmRatBN7.2
Rnor_6.0167,291,675 - 7,291,833NCBIRnor6.0
Rnor_5.0167,220,245 - 7,220,403UniSTSRnor5.0
RGSC_v3.4166,638,825 - 6,638,983UniSTSRGSC3.4
Celera168,787,111 - 8,787,269UniSTS
RH 3.4 Map1649.0UniSTS
Cytogenetic Map16p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000036910   ⟹   ENSRNOP00000032758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,364,374 - 6,400,583 (-)Ensembl
Rnor_6.0 Ensembl167,254,974 - 7,290,561 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106800   ⟹   ENSRNOP00000094287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,364,374 - 6,400,596 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113930   ⟹   ENSRNOP00000080638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,364,374 - 6,400,596 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115386   ⟹   ENSRNOP00000097646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,376,639 - 6,400,668 (-)Ensembl
RefSeq Acc Id: NM_001376918   ⟹   NP_001363847
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8166,383,078 - 6,407,104 (-)NCBI
mRatBN7.2166,376,639 - 6,400,668 (-)NCBI
RefSeq Acc Id: NM_001409024   ⟹   NP_001395953
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8166,370,809 - 6,407,037 (-)NCBI
mRatBN7.2166,364,370 - 6,400,601 (-)NCBI
RefSeq Acc Id: XM_039094446   ⟹   XP_038950374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8166,370,809 - 6,383,643 (-)NCBI
mRatBN7.2166,364,370 - 6,378,131 (-)NCBI
Ensembl Acc Id: ENSRNOP00000032758   ⟸   ENSRNOT00000036910
RefSeq Acc Id: XP_038950374   ⟸   XM_039094446
- Peptide Label: isoform X1
- UniProtKB: A6KG04 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001363847   ⟸   NM_001376918
- Peptide Label: isoform 1
- UniProtKB: A0A8I6ATD2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094287   ⟸   ENSRNOT00000106800
Ensembl Acc Id: ENSRNOP00000080638   ⟸   ENSRNOT00000113930
Ensembl Acc Id: ENSRNOP00000097646   ⟸   ENSRNOT00000115386
RefSeq Acc Id: NP_001395953   ⟸   NM_001409024
- Peptide Label: isoform 2
- UniProtKB: A0A8I6AMT4 (UniProtKB/TrEMBL),   A0A8I5ZTG9 (UniProtKB/TrEMBL)
Protein Domains
PX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4G017-F1-model_v2 AlphaFold Q4G017 1-1502 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699941
Promoter ID:EPDNEW_R10449
Type:initiation region
Name:Nisch_1
Description:nischarin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0167,290,599 - 7,290,659EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306950 AgrOrtholog
BioCyc Gene G2FUF-12159 BioCyc
Ensembl Genes ENSRNOG00000018823 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036910.6 UniProtKB/TrEMBL
  ENSRNOT00000106800.1 UniProtKB/TrEMBL
  ENSRNOT00000113930.1 UniProtKB/TrEMBL
  ENSRNOT00000115386.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7378946 IMAGE-MGC_LOAD
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nischarin_PX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112892 IMAGE-MGC_LOAD
NCBI Gene 306255 ENTREZGENE
PANTHER NISCHARIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NISCHARIN RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_4 UniProtKB/TrEMBL
  PF00787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nisch PhenoGen
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018823 RatGTEx
SMART LRR_SD22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Outer arm dynein light chain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF64268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZTG9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATD2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QGU1_RAT UniProtKB/TrEMBL
  A6KG04 ENTREZGENE, UniProtKB/TrEMBL
  NISCH_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Nisch  nischarin  Nisch_predicted  nischarin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nisch_predicted  nischarin (predicted)      Symbol and Name status set to approved 70820 APPROVED