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Gene: Nfe2l3 (nuclear factor, erythroid 2-like 3) Rattus norvegicus
Symbol: Nfe2l3
Name: nuclear factor, erythroid 2-like 3
RGD ID: 1307730
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Predicted to localize to cytoplasm and nucleus. Orthologous to human NFE2L3 (nuclear factor, erythroid 2 like 3); INTERACTS WITH benzo[a]pyrene; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC312331; nuclear factor erythroid 2-related factor 3; nuclear factor, erythroid derived 2, like 3
Homo sapiens (human) : NFE2L3 (nuclear factor, erythroid 2 like 3)  HGNC  Alliance
Mus musculus (house mouse) : Nfe2l3 (nuclear factor, erythroid derived 2, like 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfe2l3 (nuclear factor, erythroid 2 like 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NFE2L3 (nuclear factor, erythroid 2 like 3)
Canis lupus familiaris (dog) : NFE2L3 (nuclear factor, erythroid 2 like 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfe2l3 (nuclear factor, erythroid 2 like 3)
Sus scrofa (pig) : NFE2L3 (nuclear factor, erythroid 2 like 3)
Chlorocebus sabaeus (African green monkey) : NFE2L3 (nuclear factor, erythroid 2 like 3)
Heterocephalus glaber (naked mole-rat) : Nfe2l3 (nuclear factor, erythroid 2 like 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0481,205,214 - 81,233,068 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl481,205,404 - 81,232,813 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04145,871,407 - 145,901,537 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4479,668,259 - 79,695,648NCBIRGSC3.4rn4RGSC3.4
Celera475,407,547 - 75,435,350 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nfe2l3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307730
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.