Dtl (denticleless E3 ubiquitin protein ligase homolog) - Rat Genome Database

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Gene: Dtl (denticleless E3 ubiquitin protein ligase homolog) Rattus norvegicus
Analyze
Symbol: Dtl
Name: denticleless E3 ubiquitin protein ligase homolog
RGD ID: 1310439
Description: Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Predicted to be located in centrosome; cytosol; and nuclear lumen. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human DTL (denticleless E3 ubiquitin protein ligase homolog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog; denticleless homolog (Drosophila); denticleless protein homolog; LOC100909566; LOC305073; RGD1310439; similar to retinoic acid-regulated nuclear matrix-associated protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,646,908 - 105,685,921 (-)NCBIGRCr8
mRatBN7.213103,115,810 - 103,155,029 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.013110,219,276 - 110,257,345 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,220,283 - 110,257,367 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,783,177 - 114,821,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,603,353 - 107,640,812 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113107,792,703 - 107,830,078 (-)NCBI
Celera13102,555,070 - 102,594,148 (-)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (ISO)
erastin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
genistein  (ISO)
hexadecanoic acid  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
lucanthone  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
pravastatin  (EXP,ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
senecionine  (EXP)
Senkirkine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16949367   PMID:17085480   PMID:17106265   PMID:18794347   PMID:20129063   PMID:21628527   PMID:26431207  


Genomics

Comparative Map Data
Dtl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,646,908 - 105,685,921 (-)NCBIGRCr8
mRatBN7.213103,115,810 - 103,155,029 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.013110,219,276 - 110,257,345 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,220,283 - 110,257,367 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,783,177 - 114,821,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,603,353 - 107,640,812 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113107,792,703 - 107,830,078 (-)NCBI
Celera13102,555,070 - 102,594,148 (-)NCBICelera
Cytogenetic Map13q27NCBI
DTL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,035,748 - 212,105,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1212,035,553 - 212,107,400 (+)EnsemblGRCh38hg38GRCh38
GRCh371212,209,090 - 212,278,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,275,754 - 210,344,809 (+)NCBINCBI36Build 36hg18NCBI36
Celera1185,435,998 - 185,505,287 (+)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1182,885,955 - 182,955,234 (+)NCBIHuRef
CHM1_11213,481,305 - 213,550,518 (+)NCBICHM1_1
T2T-CHM13v2.01211,281,835 - 211,351,118 (+)NCBIT2T-CHM13v2.0
Dtl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,269,468 - 191,307,656 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,269,468 - 191,307,656 (-)EnsemblGRCm39 Ensembl
GRCm381191,537,356 - 191,575,544 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,537,356 - 191,575,544 (-)EnsemblGRCm38mm10GRCm38
MGSCv371193,361,244 - 193,399,413 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361193,237,980 - 193,276,149 (-)NCBIMGSCv36mm8
Celera1198,486,790 - 198,526,178 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.44NCBI
Dtl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,254,558 - 5,299,573 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554065,256,057 - 5,299,573 (-)NCBIChiLan1.0ChiLan1.0
DTL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2137,300,460 - 37,367,503 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,264,941 - 37,331,990 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01187,603,600 - 187,672,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,466,408 - 192,535,071 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,466,408 - 192,535,071 (+)Ensemblpanpan1.1panPan2
DTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1710,323,842 - 10,368,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl710,323,559 - 10,369,560 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha79,901,494 - 9,944,363 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0710,030,330 - 10,073,724 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl710,030,370 - 10,073,719 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,952,445 - 9,997,665 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0710,055,386 - 10,098,331 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0710,179,868 - 10,228,472 (+)NCBIUU_Cfam_GSD_1.0
Dtl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,087,630 - 64,149,419 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,347,991 - 1,389,836 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,347,991 - 1,389,836 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,227,705 - 131,275,451 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,225,840 - 131,275,426 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,272,743 - 144,325,340 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DTL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,418,078 - 17,485,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,418,090 - 17,485,164 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605517,940,853 - 18,008,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dtl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,612,284 - 17,662,405 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477117,612,264 - 17,660,772 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dtl
122 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:132
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000005576, ENSRNOT00000005628
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 24 24 18 9 18 28 16 35
Low 2 9 16 9 10 9 4 4 40 12 6 11 4
Below cutoff 10 16 13 13 4 7 6 7 4

Sequence


Ensembl Acc Id: ENSRNOT00000005576   ⟹   ENSRNOP00000005576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)Ensembl
Rnor_6.0 Ensembl13110,220,283 - 110,257,367 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095446   ⟹   ENSRNOP00000083831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13103,117,186 - 103,154,890 (-)Ensembl
RefSeq Acc Id: NM_001427431   ⟹   NP_001414360
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,921 (-)NCBI
RefSeq Acc Id: XM_017599014   ⟹   XP_017454503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,679,386 (-)NCBI
mRatBN7.213103,115,810 - 103,148,301 (-)NCBI
Rnor_6.013110,219,276 - 110,250,749 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091504   ⟹   XP_038947432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,873 (-)NCBI
mRatBN7.213103,115,810 - 103,154,811 (-)NCBI
RefSeq Acc Id: XM_039091506   ⟹   XP_038947434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,902 (-)NCBI
mRatBN7.213103,115,810 - 103,154,843 (-)NCBI
RefSeq Acc Id: XM_063272398   ⟹   XP_063128468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,198 (-)NCBI
RefSeq Acc Id: XM_063272399   ⟹   XP_063128469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,466 (-)NCBI
RefSeq Acc Id: XM_063272400   ⟹   XP_063128470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813105,646,908 - 105,685,739 (-)NCBI
RefSeq Acc Id: XP_017454503   ⟸   XM_017599014
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000005576   ⟸   ENSRNOT00000005576
RefSeq Acc Id: XP_038947434   ⟸   XM_039091506
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947432   ⟸   XM_039091504
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083831   ⟸   ENSRNOT00000095446
RefSeq Acc Id: NP_001414360   ⟸   NM_001427431
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128470   ⟸   XM_063272400
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128469   ⟸   XM_063272399
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128468   ⟸   XM_063272398
- Peptide Label: isoform X1
- UniProtKB: A6JGZ8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZER4-F1-model_v2 AlphaFold D3ZER4 1-783 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699133
Promoter ID:EPDNEW_R9642
Type:initiation region
Name:Dtl_1
Description:denticleless E3 ubiquitin protein ligase homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013110,257,288 - 110,257,348EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310439 AgrOrtholog
BioCyc Gene G2FUF-16841 BioCyc
Ensembl Genes ENSRNOG00000004195 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005576.8 UniProtKB/TrEMBL
  ENSRNOT00000095446.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene 305073 ENTREZGENE
PANTHER DENTICLELESS PROTEIN HOMOLOG UniProtKB/TrEMBL
  LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Dtl PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004195 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I5ZW16_RAT UniProtKB/TrEMBL
  A6JGZ8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZER4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dtl  denticleless E3 ubiquitin protein ligase homolog  LOC100909566  denticleless protein homolog  Data merged from RGD:6503029 737654 PROVISIONAL
2016-01-27 Dtl  denticleless E3 ubiquitin protein ligase homolog  Dtl  denticleless E3 ubiquitin protein ligase homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Dtl  denticleless E3 ubiquitin protein ligase homolog (Drosophila)  Dtl  denticleless homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909566  denticleless protein homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-27 Dtl  denticleless homolog (Drosophila)  RGD1310439_predicted  similar to retinoic acid-regulated nuclear matrix-associated protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1310439_predicted  similar to retinoic acid-regulated nuclear matrix-associated protein (predicted)  LOC305073_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305073_predicted  similar to retinoic acid-regulated nuclear matrix-associated protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL