Gene: Lrba (LPS responsive beige-like anchor protein) Rattus norvegicus
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Symbol: Lrba
Name: LPS responsive beige-like anchor protein
Description: INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH common variable immunodeficiency (ortholog); Common Variable Immunodeficiency 8, with Autoimmunity (ortholog); Hirschsprung Disease 1 (ortholog); FOUND IN cytoplasmic vesicle (ortholog); endoplasmic reticulum (ortholog); lysosome (ortholog); INTERACTS WITH 2,6-dinitrotoluene; bis(2-chloroethyl) sulfide; bisphenol A
AGR Description: Predicted to be involved in cellular response to leukemia inhibitory factor; predicted to localize to the cytoplasm, intracellular organelle, and plasma membrane; orthologous to human LRBA (LPS responsive beige-like anchor protein).
Merged Description: Predicted to be involved in cellular response to leukemia inhibitory factor; predicted to localize to the cytoplasm, intracellular organelle, and plasma membrane; orthologous to human LRBA (LPS responsive beige-like anchor protein); INTERACTS WITH 2,6-dinitrotoluene; bis(2-chloroethyl) sulfide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lipopolysaccharide-responsive and beige-like anchor protein; LOC361975; LPS-responsive beige-like anchor; LPS-responsive vesicle trafficking, beach and anchor containing
Orthologs:
Homo sapiens (human) : LRBA (LPS responsive beige-like anchor protein)  HGNC  Alliance
Mus musculus (house mouse) : Lrba (LPS-responsive beige-like anchor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrba (LPS responsive beige-like anchor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : LRBA (LPS responsive beige-like anchor protein)
Canis lupus familiaris (dog) : LRBA (LPS responsive beige-like anchor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrba (LPS responsive beige-like anchor protein)
Sus scrofa (pig) : LRBA (LPS responsive beige-like anchor protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02185,590,983 - 186,110,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02204,990,265 - 205,509,284 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42178,257,272 - 178,787,626 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12178,217,795 - 178,737,740 (+)NCBI
Celera2165,654,175 - 166,163,983 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lrba
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311428
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.