Chgb (chromogranin B) - Rat Genome Database

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Gene: Chgb (chromogranin B) Rattus norvegicus
Analyze
Symbol: Chgb
Name: chromogranin B
RGD ID: 2339
Description: Located in secretory granule. Orthologous to human CHGB (chromogranin B); INTERACTS WITH (S)-nicotine; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cgB; chromogranin B (secretogranin 1); Chromogranin B parathyroid secretory protein; Chromogranin B, parathyroid secretory protein; chromogranin-B; glucagonoma peptide; MGC156676; secretogranin-1; secretogranin-I; sgI
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83140,496,712 - 140,510,057 (+)NCBIGRCr8
mRatBN7.23120,043,824 - 120,057,169 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3120,043,738 - 120,057,166 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3123,938,946 - 123,952,295 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03132,542,607 - 132,555,930 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03130,195,081 - 130,208,430 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03125,428,050 - 125,441,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3125,428,260 - 125,441,594 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03131,912,022 - 131,925,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43120,571,736 - 120,584,874 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13120,477,308 - 120,490,447 (+)NCBI
Celera3118,829,899 - 118,843,230 (+)NCBICelera
RH 3.4 Map31031.0RGD
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methylcholine  (ISO)
6-propyl-2-thiouracil  (EXP)
aldehydo-D-glucose  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
Cuprizon  (EXP)
D-glucose  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
dieldrin  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dorsomorphin  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fructose  (ISO)
furan  (EXP)
genistein  (ISO)
glucose  (ISO)
kainic acid  (EXP)
L-methionine  (ISO)
lithium chloride  (ISO)
lycopene  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
Muraglitazar  (EXP)
N-ethyl-N-nitrosourea  (EXP)
nickel atom  (EXP)
nicotine  (EXP)
Oxotremorine  (EXP)
perfluorohexanesulfonic acid  (ISO)
reserpine  (EXP)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium dichromate  (ISO)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
Tesaglitazar  (EXP)
thapsigargin  (EXP)
trametinib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular space  (IBA,IEA)
secretory granule  (IBA,IDA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Nucleotide sequence and cellular distribution of rat chromogranin B (secretogranin I) mRNA in the neuroendocrine system. Forss-Petter S, etal., J Mol Neurosci 1989;1(2):63-75.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10. Localization of the secretory granule marker protein chromogranin B in the nucleus. Potential role in transcription control. Yoo SH, etal., J Biol Chem 2002 May 3;277(18):16011-21.
Additional References at PubMed
PMID:1954895   PMID:11168356   PMID:12477932   PMID:12902350   PMID:15489334   PMID:18181560   PMID:18420944   PMID:18437352   PMID:24266713   PMID:25217033   PMID:31182646  


Genomics

Comparative Map Data
Chgb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83140,496,712 - 140,510,057 (+)NCBIGRCr8
mRatBN7.23120,043,824 - 120,057,169 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3120,043,738 - 120,057,166 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3123,938,946 - 123,952,295 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03132,542,607 - 132,555,930 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03130,195,081 - 130,208,430 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03125,428,050 - 125,441,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3125,428,260 - 125,441,594 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03131,912,022 - 131,925,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43120,571,736 - 120,584,874 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13120,477,308 - 120,490,447 (+)NCBI
Celera3118,829,899 - 118,843,230 (+)NCBICelera
RH 3.4 Map31031.0RGD
Cytogenetic Map3q36NCBI
CHGB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38205,911,510 - 5,925,353 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl205,911,510 - 5,925,353 (+)EnsemblGRCh38hg38GRCh38
GRCh37205,892,156 - 5,905,999 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36205,840,168 - 5,854,003 (+)NCBINCBI36Build 36hg18NCBI36
Build 34205,840,167 - 5,854,003NCBI
Celera205,963,586 - 5,977,617 (+)NCBICelera
Cytogenetic Map20p12.3NCBI
HuRef205,848,525 - 5,862,556 (+)NCBIHuRef
CHM1_1205,892,482 - 5,906,506 (+)NCBICHM1_1
T2T-CHM13v2.0205,951,841 - 5,965,685 (+)NCBIT2T-CHM13v2.0
Chgb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392132,623,562 - 132,636,999 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2132,623,198 - 132,636,999 (+)EnsemblGRCm39 Ensembl
GRCm382132,781,642 - 132,795,079 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2132,781,278 - 132,795,079 (+)EnsemblGRCm38mm10GRCm38
MGSCv372132,607,014 - 132,620,808 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362132,472,719 - 132,486,513 (+)NCBIMGSCv36mm8
Celera2134,008,737 - 134,022,531 (+)NCBICelera
Cytogenetic Map2F2NCBI
cM Map264.74NCBI
Chgb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541516,311,621 - 16,325,019 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541516,311,769 - 16,324,962 (+)NCBIChiLan1.0ChiLan1.0
CHGB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2216,831,982 - 6,847,419 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1206,828,808 - 6,844,245 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0205,905,854 - 5,919,758 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1205,688,837 - 5,702,816 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl205,688,837 - 5,859,738 (+)Ensemblpanpan1.1panPan2
CHGB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12415,917,215 - 15,930,222 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2415,917,215 - 15,930,158 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2415,739,474 - 15,752,447 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02416,319,975 - 16,332,968 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2416,319,975 - 16,333,580 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12415,926,486 - 15,939,478 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02416,034,841 - 16,047,838 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02416,366,313 - 16,379,304 (-)NCBIUU_Cfam_GSD_1.0
Chgb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640164,694,788 - 164,708,951 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648513,126,113 - 13,140,569 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648513,126,152 - 13,140,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHGB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1714,746,997 - 14,761,995 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11714,747,282 - 14,761,995 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21715,866,036 - 15,870,070 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21715,800,576 - 15,805,992 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHGB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1232,210,079 - 32,224,123 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl232,209,433 - 32,224,204 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607112,317,185 - 12,331,403 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chgb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247416,754,407 - 6,766,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247416,754,161 - 6,766,317 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chgb
50 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:120
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000028892
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat

Markers in Region
RH94437  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23120,056,966 - 120,057,144 (+)MAPPERmRatBN7.2
Rnor_6.03125,441,399 - 125,441,576NCBIRnor6.0
Rnor_5.03131,925,177 - 131,925,354UniSTSRnor5.0
RGSC_v3.43120,584,675 - 120,584,852UniSTSRGSC3.4
Celera3118,843,028 - 118,843,205UniSTS
RH 3.4 Map31031.0UniSTS
Cytogenetic Map3q36UniSTS
UniSTS:141336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23120,056,958 - 120,057,123 (+)MAPPERmRatBN7.2
Rnor_6.03125,441,391 - 125,441,555NCBIRnor6.0
Rnor_5.03131,925,169 - 131,925,333UniSTSRnor5.0
RGSC_v3.43120,584,667 - 120,584,831UniSTSRGSC3.4
Celera3118,843,020 - 118,843,184UniSTS
Cytogenetic Map3q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 8 68 2 8
Low 4 8 7 1 7 4 4 6 8 29 6 4
Below cutoff 25 28 21 15 21 4 6 17 4 4 4

Sequence


RefSeq Acc Id: ENSRNOT00000028892   ⟹   ENSRNOP00000028892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3120,043,824 - 120,057,162 (+)Ensembl
Rnor_6.0 Ensembl3125,428,260 - 125,441,594 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094256   ⟹   ENSRNOP00000087656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3120,044,143 - 120,057,166 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106886   ⟹   ENSRNOP00000097178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3120,043,738 - 120,057,166 (+)Ensembl
RefSeq Acc Id: NM_012526   ⟹   NP_036658
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83140,496,712 - 140,510,057 (+)NCBI
mRatBN7.23120,043,824 - 120,057,169 (+)NCBI
Rnor_6.03125,428,260 - 125,441,601 (+)NCBI
Rnor_5.03131,912,022 - 131,925,379 (+)NCBI
RGSC_v3.43120,571,736 - 120,584,874 (+)RGD
Celera3118,829,899 - 118,843,230 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235072   ⟹   XP_006235134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83140,496,804 - 140,510,057 (+)NCBI
mRatBN7.23120,043,846 - 120,057,169 (+)NCBI
Rnor_6.03125,428,050 - 125,441,601 (+)NCBI
Rnor_5.03131,912,022 - 131,925,379 (+)NCBI
Sequence:
RefSeq Acc Id: NP_036658   ⟸   NM_012526
- Peptide Label: precursor
- UniProtKB: Q9QVG8 (UniProtKB/Swiss-Prot),   A1A5N9 (UniProtKB/Swiss-Prot),   Q9QVH1 (UniProtKB/Swiss-Prot),   O35314 (UniProtKB/Swiss-Prot),   A0A8L2QFU5 (UniProtKB/TrEMBL),   A6HQH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235134   ⟸   XM_006235072
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AW29 (UniProtKB/TrEMBL),   A0A8L2QFU5 (UniProtKB/TrEMBL),   A6HQH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028892   ⟸   ENSRNOT00000028892
RefSeq Acc Id: ENSRNOP00000087656   ⟸   ENSRNOT00000094256
RefSeq Acc Id: ENSRNOP00000097178   ⟸   ENSRNOT00000106886

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35314-F1-model_v2 AlphaFold O35314 1-675 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692458
Promoter ID:EPDNEW_R2981
Type:single initiation site
Name:Chgb_1
Description:chromogranin B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03125,428,460 - 125,428,520EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2339 AgrOrtholog
BioCyc Gene G2FUF-47765 BioCyc
Ensembl Genes ENSRNOG00000021269 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028892 ENTREZGENE
  ENSRNOT00000028892.5 UniProtKB/TrEMBL
  ENSRNOT00000094256.1 UniProtKB/TrEMBL
  ENSRNOT00000106886.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8370781 IMAGE-MGC_LOAD
InterPro Chromogranin_AB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromogranin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Granin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24259 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156676 IMAGE-MGC_LOAD
NCBI Gene 24259 ENTREZGENE
PANTHER PTHR10583 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SECRETOGRANIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Granin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Chgb PhenoGen
PRINTS CHROMOGRANIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GRANINS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GRANINS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021269 RatGTEx
TIGR TC228335
UniProt A0A8I6A6A1_RAT UniProtKB/TrEMBL
  A0A8I6AW29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QFU5 ENTREZGENE, UniProtKB/TrEMBL
  A1A5N9 ENTREZGENE
  A6HQH2 ENTREZGENE, UniProtKB/TrEMBL
  O35314 ENTREZGENE
  Q9QVG8 ENTREZGENE
  Q9QVH1 ENTREZGENE
  SCG1_RAT UniProtKB/Swiss-Prot
UniProt Secondary A1A5N9 UniProtKB/Swiss-Prot
  Q9QVG8 UniProtKB/Swiss-Prot
  Q9QVH1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-26 Chgb  chromogranin B  Chgb  chromogranin B (secretogranin 1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-09 Chgb  chromogranin B (secretogranin 1)  Chgb  chromogranin B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Chgb  chromogranin B    Chromogranin B, parathyroid secretory protein  Name updated 625702 APPROVED
2002-06-10 Chgb  Chromogranin B, parathyroid secretory protein      Symbol and Name status set to approved 70586 APPROVED