![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of CHGB mRNA, Nicotine results in increased expression of CHGB protein | CTD | PMID:1907749 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:10340 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CHGB mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:10340 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of CHGB mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:10340 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHGB mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:737067 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of CHGB mRNA | CTD | PMID:30165855 | 17beta-estradiol 3-benzoate | increases expression | EXP | | 6480464 | estradiol 3-benzoate results in increased expression of CHGB mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10340 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHGB mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:10340 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CHGB mRNA | CTD | PMID:21570461 | 2-methylcholine | affects expression | ISO | RGD:737067 | 6480464 | beta-methylcholine affects the expression of CHGB mRNA | CTD | PMID:21179406 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CHGB mRNA | CTD | PMID:16483693 | arsenous acid | increases expression | ISO | RGD:737067 | 6480464 | Arsenic Trioxide results in increased expression of CHGB mRNA | CTD | PMID:15761015 | benzo[a]pyrene | increases methylation | ISO | RGD:737067 | 6480464 | Benzo(a)pyrene results in increased methylation of CHGB 3' UTR | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA | CTD | PMID:31199487 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CHGB mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:737067 | 6480464 | bisphenol A results in decreased expression of CHGB mRNA | CTD | PMID:33670352 | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA | CTD | PMID:31199487 | cadmium dichloride | decreases expression | ISO | RGD:737067 | 6480464 | Cadmium Chloride results in decreased expression of CHGB mRNA | CTD | PMID:26472689 | CGP 52608 | multiple interactions | ISO | RGD:737067 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CHGB gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of CHGB mRNA | CTD | PMID:17452286 | chlorpyrifos | affects expression | ISO | RGD:10340 | 6480464 | Chlorpyrifos affects the expression of CHGB mRNA | CTD | PMID:29156651 | choline | multiple interactions | ISO | RGD:10340 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHGB mRNA | CTD | PMID:20938992 | ciguatoxin CTX1B | affects expression | ISO | RGD:10340 | 6480464 | Ciguatoxins affects the expression of CHGB mRNA | CTD | PMID:18353800 | cisplatin | decreases expression | ISO | RGD:737067 | 6480464 | Cisplatin results in decreased expression of CHGB mRNA | CTD | PMID:27392435 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CHGB mRNA | CTD | PMID:26577399 | diarsenic trioxide | increases expression | ISO | RGD:737067 | 6480464 | Arsenic Trioxide results in increased expression of CHGB mRNA | CTD | PMID:15761015 | diazinon | increases expression | EXP | | 6480464 | Diazinon results in increased expression of CHGB mRNA | CTD | PMID:17452286 | diazinon | decreases expression | EXP | | 6480464 | Diazinon results in decreased expression of CHGB mRNA | CTD | PMID:18812211 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA | CTD | PMID:31199487 | dieldrin | decreases expression | EXP | | 6480464 | Dieldrin results in decreased expression of CHGB mRNA | CTD | PMID:18812211 | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA | CTD | PMID:31199487 | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA | CTD | PMID:31199487 | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA | CTD | PMID:31199487 | dorsomorphin | multiple interactions | ISO | RGD:737067 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHGB mRNA | CTD | PMID:27188386 | ethanol | affects splicing | ISO | RGD:10340 | 6480464 | Ethanol affects the splicing of CHGB mRNA | CTD | PMID:30319688 | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of CHGB mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | ISO | RGD:10340 | 6480464 | [1 more ... | CTD | PMID:20938992, PMID:22206623 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CHGB mRNA | CTD | PMID:27387713 | genistein | decreases expression | ISO | RGD:10340 | 6480464 | Genistein results in decreased expression of CHGB mRNA | CTD | PMID:32186404 | kainic acid | increases expression | EXP | | 6480464 | Kainic Acid results in increased expression of CHGB mRNA | CTD | PMID:9427505 | L-methionine | multiple interactions | ISO | RGD:10340 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CHGB mRNA | CTD | PMID:20938992 | lithium chloride | decreases expression | ISO | RGD:10340 | 6480464 | Lithium Chloride results in decreased expression of CHGB mRNA | CTD | PMID:33901603 | lycopene | decreases expression | ISO | RGD:737067 | 6480464 | lycopene results in decreased expression of CHGB mRNA | CTD | PMID:16886892 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | methylmercury chloride | increases expression | ISO | RGD:737067 | 6480464 | methylmercuric chloride results in increased expression of CHGB mRNA | CTD | PMID:28001369 | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of CHGB mRNA | CTD | PMID:21515302 | N-ethyl-N-nitrosourea | increases expression | EXP | | 6480464 | Ethylnitrosourea results in increased expression of CHGB mRNA | CTD | PMID:15954086 | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of CHGB mRNA | CTD | PMID:18812211 | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of CHGB mRNA, Nicotine results in increased expression of CHGB protein | CTD | PMID:1907749 | Oxotremorine | increases expression | EXP | | 6480464 | Oxotremorine results in increased expression of CHGB mRNA, Oxotremorine results in increased expression of CHGB protein | CTD | PMID:1907749 | reserpine | increases expression | EXP | | 6480464 | Reserpine results in increased expression of CHGB mRNA, Reserpine results in increased expression of CHGB protein | CTD | PMID:1907749 more ... | resveratrol | increases expression | ISO | RGD:737067 | 6480464 | resveratrol results in increased expression of CHGB mRNA | CTD | PMID:25888808 | rotenone | increases oxidation | EXP | | 6480464 | Rotenone results in increased oxidation of CHGB protein | CTD | PMID:30951809 | SB 431542 | multiple interactions | ISO | RGD:737067 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHGB mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | RGD:737067 | 6480464 | Silicon Dioxide analog results in decreased expression of CHGB mRNA | CTD | PMID:25895662 | sodium dichromate | decreases expression | ISO | RGD:10340 | 6480464 | sodium bichromate results in decreased expression of CHGB mRNA | CTD | PMID:31558096 | sotorasib | multiple interactions | ISO | RGD:737067 | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHGB mRNA | CTD | PMID:36139627 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of CHGB mRNA | CTD | PMID:30047161 | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of CHGB mRNA | CTD | PMID:21515302 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of CHGB protein | CTD | PMID:35544339 | trametinib | multiple interactions | ISO | RGD:737067 | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CHGB mRNA | CTD | PMID:36139627 | trichostatin A | increases expression | ISO | RGD:737067 | 6480464 | trichostatin A results in increased expression of CHGB mRNA | CTD | PMID:24935251 | triclosan | increases expression | ISO | RGD:737067 | 6480464 | Triclosan results in increased expression of CHGB mRNA | CTD | PMID:30510588 | triptonide | increases expression | ISO | RGD:10340 | 6480464 | triptonide results in increased expression of CHGB mRNA | CTD | PMID:33045310 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of CHGB mRNA | CTD | PMID:21515302 | tunicamycin | increases expression | ISO | RGD:737067 | 6480464 | Tunicamycin results in increased expression of CHGB mRNA | CTD | PMID:29453283 | urethane | increases expression | ISO | RGD:737067 | 6480464 | Urethane results in increased expression of CHGB mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | RGD:737067 | 6480464 | Valproic Acid affects the expression of CHGB mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | RGD:737067 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHGB mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:737067 | 6480464 | Valproic Acid results in increased expression of CHGB mRNA | CTD | PMID:23179753 more ... | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of CHGB mRNA | CTD | PMID:20566332 | |