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Gene: Asxl1 (ASXL transcriptional regulator 1) Rattus norvegicus
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Symbol: Asxl1
Name: ASXL transcriptional regulator 1
Description: Predicted to have peroxisome proliferator activated receptor binding activity; retinoic acid receptor binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including animal organ development; monoubiquitinated histone H2A deubiquitination; and regulation of signal transduction. Predicted to localize to the PR-DUB complex. Human ortholog(s) of this gene implicated in SM-AHNMD; acute myeloid leukemia; chronic myelomonocytic leukemia; myelodysplastic syndrome; and myelofibrosis. Orthologous to human ASXL1 (ASXL transcriptional regulator 1); INTERACTS WITH bisphenol A; cobalt dichloride; oxaliplatin.
Type: protein-coding
RefSeq Status: MODEL
Also known as: additional sex combs like 1; additional sex combs like 1, transcriptional regulator; additional sex combs like transcriptional regulator 1; LOC311553; LOW QUALITY PROTEIN: putative Polycomb group protein ASXL1; putative Polycomb group protein ASXL1; RGD1561878; similar to mKIAA0978 protein
Orthologs:
Homo sapiens (human) : ASXL1 (ASXL transcriptional regulator 1)  HGNC  Alliance
Mus musculus (house mouse) : Asxl1 (additional sex combs like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asxl1 (ASXL transcriptional regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ASXL1 (ASXL transcriptional regulator 1)
Canis lupus familiaris (dog) : ASXL1 (ASXL transcriptional regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asxl1 (ASXL transcriptional regulator 1)
Sus scrofa (pig) : ASXL1 (ASXL transcriptional regulator 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03148,832,231 - 148,902,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,837,814 - 148,900,452 (+)Ensembl
Rnor_5.03155,202,740 - 155,267,814 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,703,295 - 143,767,523 (+)NCBIRGSC3.4rn4RGSC3.4
Celera3140,560,551 - 140,627,551 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Asxl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561878
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.