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Gene: Slc22a3 (solute carrier family 22 member 3) Rattus norvegicus
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Symbol: Slc22a3
Name: solute carrier family 22 member 3
Description: Exhibits dopamine:sodium symporter activity; quaternary ammonium group transmembrane transporter activity; and toxin transmembrane transporter activity. Involved in dopamine transport and quaternary ammonium group transport. Predicted to localize to integral component of membrane. Orthologous to human SLC22A3 (solute carrier family 22 member 3); PARTICIPATES IN lamivudine pharmacokinetics pathway; metformin pharmacokinetics pathway; INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 1,1'-diethyl-2,2'-cyanine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: organic cation transporter 3; solute carrier family 22 (extraneuronal monoamine transporter), member 3; solute carrier family 22 (organic cation transporter), member 3; solute carrier family 22, member 3
Orthologs:
Homo sapiens (human) : SLC22A3 (solute carrier family 22 member 3)  HGNC  Alliance
Mus musculus (house mouse) : Slc22a3 (solute carrier family 22 (organic cation transporter), member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a3 (solute carrier family 22 member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A3 (solute carrier family 22 member 3)
Canis lupus familiaris (dog) : SLC22A3 (solute carrier family 22 member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a3 (solute carrier family 22 member 3)
Sus scrofa (pig) : SLC22A3 (solute carrier family 22 member 3)
Chlorocebus sabaeus (African green monkey) : SLC22A3 (solute carrier family 22 member 3)
Heterocephalus glaber (naked mole-rat) : Slc22a3 (solute carrier family 22 member 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0148,433,079 - 48,521,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,433,079 - 48,521,256 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,234,467 - 51,321,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,690,158 - 42,781,895 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,693,102 - 42,784,835 (+)NCBI
Celera144,028,160 - 44,116,659 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc22a3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3701
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.