Pank2 (pantothenate kinase 2) - Rat Genome Database

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Gene: Pank2 (pantothenate kinase 2) Rattus norvegicus
Analyze
Symbol: Pank2
Name: pantothenate kinase 2
RGD ID: 1305169
Description: Predicted to enable pantothenate kinase activity. Predicted to be involved in angiogenesis; coenzyme A biosynthetic process; and regulation of lipid metabolic process. Predicted to act upstream of or within several processes, including aerobic respiration; regulation of mitochondrial membrane potential; and spermatid development. Predicted to be located in mitochondrion. Predicted to be active in cytosol; mitochondrial intermembrane space; and nucleus. Human ortholog(s) of this gene implicated in pantothenate kinase-associated neurodegeneration. Orthologous to human PANK2 (pantothenate kinase 2); PARTICIPATES IN pantothenic acid metabolic pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; bisphenol A; fipronil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC296167; pantothenate kinase 2 (Hallervorden-Spatz syndrome); pantothenate kinase 2, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,936,448 - 138,974,196 (+)NCBIGRCr8
mRatBN7.23118,483,382 - 118,519,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,483,444 - 118,518,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,377,611 - 122,412,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,977,021 - 131,011,891 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,633,718 - 128,668,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,807,911 - 123,841,797 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,807,952 - 123,841,797 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,303,253 - 130,340,189 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,970,527 - 119,004,728 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,874,080 - 118,910,207 (+)NCBI
Celera3117,291,291 - 117,326,233 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11479594   PMID:15525657   PMID:17825826   PMID:18614015   PMID:22221393   PMID:22815849   PMID:22983956   PMID:23152917  


Genomics

Comparative Map Data
Pank2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,936,448 - 138,974,196 (+)NCBIGRCr8
mRatBN7.23118,483,382 - 118,519,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,483,444 - 118,518,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,377,611 - 122,412,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,977,021 - 131,011,891 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,633,718 - 128,668,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,807,911 - 123,841,797 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,807,952 - 123,841,797 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,303,253 - 130,340,189 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,970,527 - 119,004,728 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,874,080 - 118,910,207 (+)NCBI
Celera3117,291,291 - 117,326,233 (+)NCBICelera
Cytogenetic Map3q36NCBI
PANK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,888,781 - 3,929,887 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,888,839 - 3,929,887 (+)EnsemblGRCh38hg38GRCh38
GRCh37203,869,428 - 3,910,534 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,817,486 - 3,852,502 (+)NCBINCBI36Build 36hg18NCBI36
Build 34203,818,456 - 3,852,501NCBI
Celera203,931,353 - 3,966,375 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,818,171 - 3,853,155 (+)NCBIHuRef
CHM1_1203,869,486 - 3,904,501 (+)NCBICHM1_1
T2T-CHM13v2.0203,919,717 - 3,960,811 (+)NCBIT2T-CHM13v2.0
Pank2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392131,103,928 - 131,141,108 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2131,104,415 - 131,141,108 (+)EnsemblGRCm39 Ensembl
GRCm382131,262,008 - 131,299,188 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,262,495 - 131,299,188 (+)EnsemblGRCm38mm10GRCm38
MGSCv372131,088,236 - 131,124,924 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,953,941 - 130,988,132 (+)NCBIMGSCv36mm8
Celera2132,488,862 - 132,525,361 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.31NCBI
Pank2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,723,087 - 14,751,423 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,722,951 - 14,752,493 (+)NCBIChiLan1.0ChiLan1.0
PANK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,851,394 - 4,886,600 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,848,256 - 4,883,409 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,924,054 - 3,959,393 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,723,211 - 3,757,748 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,723,211 - 3,757,748 (+)Ensemblpanpan1.1panPan2
PANK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,461,406 - 17,475,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,463,447 - 17,490,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,289,857 - 17,319,601 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02417,878,250 - 17,908,675 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2417,881,208 - 17,908,663 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,473,257 - 17,503,635 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,585,849 - 17,614,588 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02417,912,622 - 17,942,441 (-)NCBIUU_Cfam_GSD_1.0
Pank2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,353,587 - 166,381,146 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648514,785,467 - 14,811,117 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648514,785,050 - 14,804,258 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PANK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,798,785 - 31,828,496 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11731,797,604 - 31,844,301 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,139,594 - 36,169,170 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PANK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,577,859 - 34,612,258 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl234,578,207 - 34,611,987 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660719,839,672 - 9,873,822 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pank2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,966,260 - 5,007,207 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,966,136 - 5,025,465 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pank2
125 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:303
Count of miRNA genes:194
Interacting mature miRNAs:225
Transcripts:ENSRNOT00000033554
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat

Markers in Region
AI642621  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,515,098 - 118,515,220 (+)MAPPERmRatBN7.2
Rnor_6.03123,838,576 - 123,838,697NCBIRnor6.0
Rnor_5.03130,334,157 - 130,334,278UniSTSRnor5.0
RGSC_v3.43119,001,507 - 119,001,628UniSTSRGSC3.4
Celera3117,323,012 - 117,323,133UniSTS
Cytogenetic Map3q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 46 30 19 30 8 10 74 34 41 11 8
Low 1 11 11 11 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC105811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000033554   ⟹   ENSRNOP00000036035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,483,474 - 118,518,320 (+)Ensembl
Rnor_6.0 Ensembl3123,807,952 - 123,841,797 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095861   ⟹   ENSRNOP00000078713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,483,444 - 118,518,293 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111155   ⟹   ENSRNOP00000080556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,495,994 - 118,515,353 (+)Ensembl
RefSeq Acc Id: NM_001106513   ⟹   NP_001099983
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,508 - 138,971,353 (+)NCBI
mRatBN7.23118,483,474 - 118,518,320 (+)NCBI
Rnor_6.03123,807,952 - 123,841,797 (+)NCBI
Rnor_5.03130,303,253 - 130,340,189 (+)NCBI
RGSC_v3.43118,970,527 - 119,004,728 (+)RGD
Celera3117,291,291 - 117,326,233 (+)RGD
Sequence:
RefSeq Acc Id: XM_017591584   ⟹   XP_017447073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,454 - 138,971,013 (+)NCBI
mRatBN7.23118,483,418 - 118,519,551 (+)NCBI
Rnor_6.03123,807,911 - 123,841,793 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104583   ⟹   XP_038960511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,452 - 138,971,013 (+)NCBI
mRatBN7.23118,483,410 - 118,519,551 (+)NCBI
RefSeq Acc Id: XM_039104584   ⟹   XP_038960512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,454 - 138,971,013 (+)NCBI
mRatBN7.23118,483,418 - 118,519,551 (+)NCBI
RefSeq Acc Id: XM_039104586   ⟹   XP_038960514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,450 - 138,971,013 (+)NCBI
mRatBN7.23118,483,405 - 118,519,551 (+)NCBI
RefSeq Acc Id: XM_039104587   ⟹   XP_038960515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,454 - 138,971,013 (+)NCBI
mRatBN7.23118,483,418 - 118,519,551 (+)NCBI
RefSeq Acc Id: XM_039104588   ⟹   XP_038960516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,448 - 138,955,304 (+)NCBI
mRatBN7.23118,483,382 - 118,502,333 (+)NCBI
RefSeq Acc Id: XM_063283333   ⟹   XP_063139403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,452 - 138,970,363 (+)NCBI
RefSeq Acc Id: XM_063283334   ⟹   XP_063139404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,455 - 138,970,363 (+)NCBI
RefSeq Acc Id: XM_063283335   ⟹   XP_063139405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,652 - 138,970,363 (+)NCBI
RefSeq Acc Id: XM_063283337   ⟹   XP_063139407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,652 - 138,974,196 (+)NCBI
RefSeq Acc Id: XR_010064584
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,936,449 - 138,962,778 (+)NCBI
RefSeq Acc Id: NP_001099983   ⟸   NM_001106513
- UniProtKB: F1LT70 (UniProtKB/TrEMBL),   A6HQD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447073   ⟸   XM_017591584
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000036035   ⟸   ENSRNOT00000033554
RefSeq Acc Id: XP_038960516   ⟸   XM_039104588
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038960514   ⟸   XM_039104586
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038960511   ⟸   XM_039104583
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038960512   ⟸   XM_039104584
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038960515   ⟸   XM_039104587
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000078713   ⟸   ENSRNOT00000095861
RefSeq Acc Id: ENSRNOP00000080556   ⟸   ENSRNOT00000111155
RefSeq Acc Id: XP_063139403   ⟸   XM_063283333
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063139404   ⟸   XM_063283334
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063139407   ⟸   XM_063283337
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063139405   ⟸   XM_063283335
- Peptide Label: isoform X6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LT70-F1-model_v2 AlphaFold F1LT70 1-443 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692449
Promoter ID:EPDNEW_R2974
Type:initiation region
Name:Pank2_1
Description:pantothenate kinase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03123,807,914 - 123,807,974EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305169 AgrOrtholog
BioCyc Gene G2FUF-47817 BioCyc
BioCyc Pathway COA-PWY-1 [superpathway of coenzyme A biosynthesis III (mammals)] BioCyc
BioCyc Pathway Image COA-PWY-1 BioCyc
Ensembl Genes ENSRNOG00000025286 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033554 ENTREZGENE
  ENSRNOT00000033554.6 UniProtKB/TrEMBL
  ENSRNOT00000095861.1 UniProtKB/TrEMBL
  ENSRNOT00000111155.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.40 UniProtKB/TrEMBL
  3.30.420.510 UniProtKB/TrEMBL
InterPro ATPase_NBD UniProtKB/TrEMBL
  Type_II_PanK UniProtKB/TrEMBL
KEGG Report rno:296167 UniProtKB/TrEMBL
NCBI Gene 296167 ENTREZGENE
PANTHER PANTOTHENATE KINASE 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12280 UniProtKB/TrEMBL
Pfam Fumble UniProtKB/TrEMBL
PhenoGen Pank2 PhenoGen
RatGTEx ENSRNOG00000025286 RatGTEx
Superfamily-SCOP SSF53067 UniProtKB/TrEMBL
UniProt A0A8I5ZQX7_RAT UniProtKB/TrEMBL
  A0A8I6G278_RAT UniProtKB/TrEMBL
  A6HQD5 ENTREZGENE, UniProtKB/TrEMBL
  F1LT70 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Pank2  pantothenate kinase 2  Pank2  pantothenate kinase 2 (Hallervorden-Spatz syndrome)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pank2  pantothenate kinase 2 (Hallervorden-Spatz syndrome)   Pank2_predicted  pantothenate kinase 2 (Hallervorden-Spatz syndrome) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pank2_predicted  pantothenate kinase 2 (Hallervorden-Spatz syndrome) (predicted)      Symbol and Name status set to approved 70820 APPROVED