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Gene: Pdk3 (pyruvate dehydrogenase kinase 3) Rattus norvegicus
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Symbol: Pdk3
Name: pyruvate dehydrogenase kinase 3
Description: Predicted to have ATP binding activity; protein serine/threonine kinase activity; and pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in cellular response to glucose stimulus. Predicted to localize to the mitochondrion and nucleolus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 6. Orthologous to human PDK3 (pyruvate dehydrogenase kinase 3); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH acrylamide; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial; Pdk3_mapped; pyruvate dehydrogenase kinase, isoenzyme 3; pyruvate dehydrogenase kinase, isoenzyme 3 (mapped); pyruvate dehydrogenase kinase, isozyme 3
Orthologs:
Homo sapiens (human) : PDK3 (pyruvate dehydrogenase kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Pdk3 (pyruvate dehydrogenase kinase, isoenzyme 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdk3 (pyruvate dehydrogenase kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PDK3 (pyruvate dehydrogenase kinase 3)
Canis lupus familiaris (dog) : PDK3 (pyruvate dehydrogenase kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdk3 (pyruvate dehydrogenase kinase 3)
Sus scrofa (pig) : PDK3 (pyruvate dehydrogenase kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X62,836,131 - 62,904,114 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX62,836,131 - 62,903,554 (-)Ensembl
Rnor_5.0X63,428,816 - 63,497,161 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X81,104,667 - 81,171,536 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX58,924,116 - 58,991,740 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdk3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593276
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.