(6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide multiple interactions ISO RGD:731795 6480464 Methylergonovine binds to and results in increased activity of HTR2B protein CTD PMID:11104741 (R)-noradrenaline multiple interactions EXP 6480464 N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea inhibits the reaction [Norepinephrine results in increased expression of HTR2B protein] CTD PMID:20374255 (R)-noradrenaline increases expression EXP 6480464 Norepinephrine results in increased expression of HTR2B protein CTD PMID:20374255 17beta-estradiol increases expression ISO RGD:731795 6480464 Estradiol results in increased expression of HTR2B mRNA CTD PMID:31614463 1D-myo-inositol 1,4,5-trisphosphate decreases abundance ISO RGD:731795 6480464 HTR2B protein mutant form results in decreased abundance of Inositol 1 more ... CTD PMID:15625277 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HTR2B mRNA CTD PMID:32109520 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:731795 6480464 2 more ... CTD PMID:26705709 2-hydroxypropanoic acid increases expression ISO RGD:731795 6480464 Lactic Acid results in increased expression of HTR2B mRNA CTD PMID:30851411 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3,4-methylenedioxymethamphetamine multiple interactions ISO RGD:731795 6480464 N-Methyl-3, 4-methylenedioxyamphetamine inhibits the reaction [Lysergic Acid Diethylamide binds to HTR2B protein] CTD PMID:29458138 3,7-dihydropurine-6-thione increases expression EXP 6480464 Mercaptopurine results in increased expression of HTR2B mRNA CTD PMID:23358152 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:62093 6480464 bisindolylmaleimide I inhibits the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein], bisindolylmaleimide I inhibits the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731795 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of HTR2B mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HTR2B mRNA CTD PMID:36041667 aflatoxin B1 increases methylation ISO RGD:731795 6480464 Aflatoxin B1 results in increased methylation of HTR2B exon CTD PMID:30157460 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HTR2B mRNA CTD PMID:16483693 benzo[a]pyrene increases methylation ISO RGD:731795 6480464 Benzo(a)pyrene results in increased methylation of HTR2B promoter CTD PMID:27901495 Benzo[k]fluoranthene decreases expression ISO RGD:62093 6480464 benzo(k)fluoranthene results in decreased expression of HTR2B mRNA CTD PMID:26377693 bisphenol A increases expression ISO RGD:62093 6480464 bisphenol A results in increased expression of HTR2B mRNA CTD PMID:26063408 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HTR2B mRNA CTD PMID:36041667 bisphenol A decreases methylation ISO RGD:731795 6480464 bisphenol A results in decreased methylation of HTR2B gene CTD PMID:31601247 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of HTR2B gene CTD PMID:28505145 bisphenol A increases expression ISO RGD:731795 6480464 bisphenol A results in increased expression of HTR2B mRNA CTD PMID:27685785 , PMID:29275510 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HTR2B mRNA CTD PMID:25181051 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HTR2B mRNA CTD PMID:36041667 bortezomib decreases expression ISO RGD:731795 6480464 Bortezomib results in decreased expression of HTR2B mRNA CTD PMID:20977926 butanal decreases expression ISO RGD:731795 6480464 butyraldehyde results in decreased expression of HTR2B mRNA CTD PMID:26079696 calcium atom multiple interactions ISO RGD:62093 6480464 Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein], Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 calcium(0) multiple interactions ISO RGD:62093 6480464 Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein], Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of HTR2B mRNA CTD PMID:17452286 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of HTR2B mRNA CTD PMID:18835401 clofibrate multiple interactions ISO RGD:62093 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HTR2B mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HTR2B mRNA] CTD PMID:17585979 copper atom multiple interactions ISO RGD:731795 6480464 [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 copper(0) multiple interactions ISO RGD:731795 6480464 [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 dexamethasone multiple interactions ISO RGD:731795 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of HTR2B mRNA CTD PMID:28628672 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of HTR2B mRNA CTD PMID:18835401 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of HTR2B mRNA CTD PMID:18835401 dioxygen multiple interactions ISO RGD:62093 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of HTR2B mRNA CTD PMID:30529165 disulfiram multiple interactions ISO RGD:731795 6480464 [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 ergotamine multiple interactions ISO RGD:731795 6480464 Ergotamine binds to and results in increased activity of HTR2B protein CTD PMID:11104741 fenfluramine increases response to substance ISO RGD:731795 6480464 HTR2B gene mutant form results in increased susceptibility to Fenfluramine CTD PMID:14659797 fenfluramine affects binding ISO RGD:731795 6480464 Fenfluramine binds to HTR2B protein CTD PMID:10617681 fluoxetine increases expression ISO RGD:62093 6480464 Fluoxetine results in increased expression of HTR2B mRNA CTD PMID:21083617 fluoxetine increases activity ISO RGD:62093 6480464 Fluoxetine results in increased activity of HTR2B protein CTD PMID:18758753 fluoxetine multiple interactions ISO RGD:62093 6480464 1 more ... CTD PMID:11930908 more ... furan increases expression EXP 6480464 furan results in increased expression of HTR2B mRNA CTD PMID:27387713 genistein increases expression ISO RGD:62093 6480464 Genistein results in increased expression of HTR2B mRNA CTD PMID:32186404 glycogen multiple interactions ISO RGD:62093 6480464 [Fluoxetine results in increased expression of and results in increased activity of HTR2B protein] which results in increased metabolism of Glycogen CTD PMID:11930908 hexadecanoic acid increases expression ISO RGD:731795 6480464 Palmitic Acid results in increased expression of HTR2B protein CTD PMID:27133527 indometacin multiple interactions ISO RGD:731795 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of HTR2B mRNA CTD PMID:28628672 lipopolysaccharide decreases expression ISO RGD:62093 6480464 Lipopolysaccharides results in decreased expression of HTR2B mRNA CTD PMID:12057914 lysergic acid diethylamide multiple interactions ISO RGD:731795 6480464 2-aminoindan analog inhibits the reaction [Lysergic Acid Diethylamide binds to HTR2B protein] more ... CTD PMID:14659797 , PMID:29458138 lysergic acid diethylamide affects binding ISO RGD:731795 6480464 Lysergic Acid Diethylamide binds to HTR2B protein CTD PMID:29458138 mercaptopurine increases expression EXP 6480464 Mercaptopurine results in increased expression of HTR2B mRNA CTD PMID:23358152 mesulergine affects binding ISO RGD:62093 6480464 mesulergine binds to HTR2B protein CTD PMID:11930908 mesulergine multiple interactions ISO RGD:62093 6480464 Fluoxetine promotes the reaction [mesulergine binds to HTR2B protein] CTD PMID:11930908 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of HTR2B mRNA CTD PMID:15644446 Methylergonovine Maleate multiple interactions ISO RGD:731795 6480464 Methylergonovine binds to and results in increased activity of HTR2B protein CTD PMID:11104741 mifepristone increases expression ISO RGD:731795 6480464 Mifepristone results in increased expression of HTR2B mRNA CTD PMID:17584828 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of HTR2B mRNA, Diethylnitrosamine results in decreased expression of HTR2B protein CTD PMID:27565560 paracetamol multiple interactions ISO RGD:62093 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HTR2B mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HTR2B mRNA] CTD PMID:17585979 pentanal decreases expression ISO RGD:731795 6480464 pentanal results in decreased expression of HTR2B mRNA CTD PMID:26079696 pioglitazone multiple interactions ISO RGD:62093 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of HTR2B mRNA CTD PMID:27935865 pirinixic acid increases expression ISO RGD:62093 6480464 pirinixic acid results in increased expression of HTR2B mRNA CTD PMID:18301758 progesterone decreases expression ISO RGD:731795 6480464 Progesterone results in decreased expression of HTR2B mRNA CTD PMID:21795739 propanal decreases expression ISO RGD:731795 6480464 propionaldehyde results in decreased expression of HTR2B mRNA CTD PMID:26079696 purine-6-thiol increases expression EXP 6480464 Mercaptopurine results in increased expression of HTR2B mRNA CTD PMID:23358152 rac-lactic acid increases expression ISO RGD:731795 6480464 Lactic Acid results in increased expression of HTR2B mRNA CTD PMID:30851411 ritanserin multiple interactions ISO RGD:62093 6480464 Ritanserin binds to and results in decreased activity of HTR2B protein CTD PMID:10978843 SB 206553 multiple interactions EXP 6480464 SB 206553 binds to and results in decreased activity of HTR2B protein CTD PMID:16521035 serotonin increases expression ISO RGD:62093 6480464 Serotonin results in increased expression of HTR2B mRNA CTD PMID:21083617 serotonin affects binding ISO RGD:731795 6480464 Serotonin binds to HTR2B protein CTD PMID:9857084 serotonin multiple interactions ISO RGD:731795 6480464 1-(5-fluoropentyl)-3-(1-naphthoyl)indole inhibits the reaction [Serotonin binds to and results in increased activity of HTR2B protein] more ... CTD PMID:27449567 , PMID:9857084 serotonin affects response to substance EXP 6480464 HTR2B protein affects the susceptibility to Serotonin CTD PMID:8627522 tetrachloromethane affects expression ISO RGD:62093 6480464 Carbon Tetrachloride affects the expression of HTR2B mRNA CTD PMID:17484886 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of HTR2B mRNA CTD PMID:33387578 tyrphostin AG 1478 multiple interactions ISO RGD:62093 6480464 RTKI cpd inhibits the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein], RTKI cpd inhibits the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 valproic acid decreases methylation ISO RGD:731795 6480464 Valproic Acid results in decreased methylation of HTR2B gene CTD PMID:29154799 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of HTR2B mRNA CTD PMID:23034163 XL147 multiple interactions ISO RGD:62093 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of HTR2B mRNA CTD PMID:27935865
