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Gene: Htr2b (5-hydroxytryptamine receptor 2B) Chinchilla lanigera

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Symbol:

Htr2b

Name:

5-hydroxytryptamine receptor 2B

RGD ID:

8999023

Description:

ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); Gq/11-coupled serotonin receptor activity (ortholog); INVOLVED IN calcium-mediated signaling (ortholog); cardiac muscle hypertrophy (ortholog); cellular response to amine stimulus (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); brain infarction (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); G protein-coupled serotonin receptor complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	4,351,668 - 4,367,807 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	4,352,278 - 4,367,807 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bardet-Biedl syndrome (ISO)

brain infarction (ISO)

Cardiomegaly (ISO)

congestive heart failure (ISO)

Experimental Liver Cirrhosis (ISO)

heart valve disease (ISO)

hypertension (ISO)

hypertrophic cardiomyopathy (ISO)

Joubert syndrome 22 (ISO)

metabolic dysfunction-associated steatohepatitis (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

Perlman syndrome (ISO)

pulmonary hypertension (ISO)

steatotic liver disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium-mediated signaling (ISO)

cardiac muscle hypertrophy (ISO)

cellular response to amine stimulus (ISO)

cellular response to serotonin (ISO)

cGMP-mediated signaling (ISO)

embryonic morphogenesis (ISO)

ERK1 and ERK2 cascade (ISO)

G protein-coupled receptor signaling pathway (ISO)

G protein-coupled serotonin receptor signaling pathway (ISO)

heart development (ISO)

heart morphogenesis (ISO)

hepatic stellate cell activation (ISO)

inositol phosphate metabolic process (ISO)

intestine smooth muscle contraction (ISO)

intracellular calcium ion homeostasis (ISO)

monoatomic ion transmembrane transport (ISO)

negative regulation of apoptotic process (ISO)

neural crest cell differentiation (ISO)

neural crest cell migration (ISO)

phospholipase C-activating serotonin receptor signaling pathway (ISO)

positive regulation of canonical NF-kappaB signal transduction (ISO)

positive regulation of cell division (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of cytokine production (ISO)

positive regulation of endothelial cell proliferation (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of phosphatidylinositol biosynthetic process (ISO)

regulation of behavior (ISO)

release of sequestered calcium ion into cytosol (ISO)

response to xenobiotic stimulus (ISO)

vasoconstriction (ISO)

Cellular Component

cytoplasm (ISO)

dendrite (ISO)

G protein-coupled serotonin receptor complex (ISO)

neuronal cell body (ISO)

nucleoplasm (ISO)

plasma membrane (ISO)

Molecular Function

G protein-coupled serotonin receptor activity (ISO)

G-protein alpha-subunit binding (ISO)

Gq/11-coupled serotonin receptor activity (ISO)

GTPase activator activity (ISO)

protein binding (ISO)

serotonin binding (ISO)

serotonin receptor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Htr2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	4,351,668 - 4,367,807 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	4,352,278 - 4,367,807 (+)	NCBI	ChiLan1.0	ChiLan1.0

HTR2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	231,108,230 - 231,125,042 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	231,108,230 - 231,125,042 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	231,972,944 - 231,989,756 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	231,681,199 - 231,698,068 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	231,798,459 - 231,815,329	NCBI
Celera	2	225,748,458 - 225,765,335 (-)	NCBI		Celera
Cytogenetic Map	2	q37.1	NCBI
HuRef	2	223,815,006 - 223,831,883 (-)	NCBI		HuRef
CHM1_1	2	231,978,806 - 231,995,681 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	231,592,736 - 231,609,548 (-)	NCBI		T2T-CHM13v2.0

Htr2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	86,025,268 - 86,043,960 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	86,026,748 - 86,039,692 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	86,097,546 - 86,116,231 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	86,099,026 - 86,111,970 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	87,995,612 - 88,008,545 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	87,930,442 - 87,942,088 (-)	NCBI		MGSCv36	mm8
Celera	1	89,064,379 - 89,077,312 (-)	NCBI		Celera
Cytogenetic Map	1	C5	NCBI
cM Map	1	43.94	NCBI

Htr2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	94,184,442 - 94,206,851 (-)	NCBI		GRCr8
mRatBN7.2	9	86,735,793 - 86,756,638 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	86,742,102 - 86,755,108 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	95,160,066 - 95,174,072 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	100,288,563 - 100,302,570 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	98,670,337 - 98,684,343 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	93,112,781 - 93,130,135 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	93,112,805 - 93,125,014 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	92,836,402 - 92,856,220 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	84,840,026 - 84,852,984 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	85,023,439 - 85,036,403 (-)	NCBI
Celera	9	84,162,612 - 84,175,882 (-)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

HTR2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	133,720,071 - 133,758,758 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	133,735,036 - 133,773,723 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	118,362,719 - 118,381,253 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	237,153,709 - 237,174,356 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	237,153,709 - 237,170,591 (-)	Ensembl	panpan1.1		panPan2

HTR2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	43,042,306 - 43,056,361 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	43,042,173 - 43,056,612 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	43,602,608 - 43,616,665 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	43,299,319 - 43,313,380 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	43,299,186 - 43,314,350 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	43,227,978 - 43,242,026 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	43,070,901 - 43,084,964 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	43,226,286 - 43,240,447 (-)	NCBI		UU_Cfam_GSD_1.0

Htr2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	185,210,647 - 185,227,546 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	5,712,329 - 5,729,831 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936525	5,711,894 - 5,729,074 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HTR2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	131,844,992 - 131,859,277 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	131,844,578 - 131,860,417 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	145,561,472 - 145,577,989 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HTR2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	117,132,919 - 117,152,132 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	117,133,195 - 117,149,681 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	82,292,351 - 82,310,254 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Htr2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624843	4,408,424 - 4,424,168 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624843	4,407,055 - 4,424,585 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005395400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005395401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005395402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01044686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01237410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000017209 ⟹ ENSCLAP00000017042

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955453	4,351,668 - 4,367,807 (+)	Ensembl

RefSeq Acc Id:

XM_005395400 ⟹ XP_005395457

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	4,352,388 - 4,367,807 (+)	NCBI

Sequence:

show sequence

CAGCCACAGCCGCAAGCAAGCGAGTACACTGAACAGATACGACAACGACATGCTCTGCCAGGTC
ACAAGCAAATGAGAGGAAGGAGTCAACTTTGGCTTTGAGTGTCTGACCTGGGTACAATTCCTTA
AAAAAAGAGACGACCAGCTTAGCTACTGACCATGGACTGAATCACAGAAAACTGGAACTGGACT
GAATCACAGAAAAACGGCGAATGGCTTTCTCTTATAGGATGTCTGAACACAGCAAAATTCCCAA
GCATGTTTTGCAGAGTACACTTCATGGCTTAATCTCTTCTAACTGGTCTGGATTTCAGAAAGGA
TCAATACCAGAGGAAATGAAACAGACTGTTGAGGAACAGGGAAATAAGCCGCACTGGGCAGCTC
TTCTGATACTCATGGTGATAATACCAACCATTGGTGGAAACATCCTTGTTATTCTGGCTGTTTC
ACTGGAGAAAAAGCTGCAGTACGCTACCAATTACTTTCTTATGTCCTTGGCGGTGGCTGATTTG
CTGGTTGGATTGTTTGTGATGCCAATTGCACTCTTGACAATAATGTTTGAGGCTATGTGGCCCC
TCCCACTTGTTCTGTGTCCTGCCTGGTTGTTTCTTGATGTTCTCTTTTCAACTGCATCCATCTT
ACACCTCTGTGCCATTTCAGTGGACCGCTACATAGCCATCAAAAAGCCAATCCAGGCCAATCAA
TATAACTCCCGAGCTACTGCACTCATCAAGATTACAGTGGTGTGGTTAATTTCAATAGGCATTG
CCATTCCAGTCCCTATTAAAGGGATAGATACTGATGTGCCTAACCCTAACAATATCACCTGTGC
ACTGACAAAGGAGCGTTTTGGCAATTTCATGCTTTTTGGCTCCCTTGCTGCCTTCTTCACACCT
CTTGCAATCATGATTGTCACCTACTTTCTCACCATCCATGCTCTACAGAAGAAAGCTTACTTGG
TCAAAAACAAGGCACCTCAGCGTCTCCCATGGCTGAATGTGTCCACAGTATTTCAAAGAGATGA
AACTCCCTGCTCATCACCCGAGAAGGCGGCAATGCTGGGTGGTTCTCACAAGAACAAAACTCTG
CCCAACTCAAGTGATGAAACCCTCACGCGACGGATGTCCACAACTGGAAAAAAGTCTGCCCAAA
CTATTTCTAATGAGCAGAGAGCCTCAAAGGTCCTTGGAATTGTATTTTTCCTCTTTTTGCTTAT
GTGGTGCCCTTTTTTTATTACAAATATTACTTTAGCTTTGTGTGACTCCTGCAACCAGACTACT
CTTAAAATGCTCCTGGAGATTTTTGTGTGGATAGGCTACATTTCCTCTGGGGTGAATCCTTTGG
TCTATACTCTCTTCAACAAGACATTTCGGGATGCATTTGGTCGATATATCACCTGCAATTACCA
GGCTACAAAGTCAGCAAAAACTGTTAGAAAATGCTCCGGTAAGGTCTACTTCCGGAATCCGATG
AAAGAGAACTCCAAATTTTTCACAAAACGTGGAATGCGAAATGGGGTTAATCCTACCATGTACC
AGAGCCCAAAGAGGCTCCGAAACTCAACCATTCAGTCTTCATCAGTCATTCCACTAGACACTCT
TCTCCTCACTGAAAATGAAGGTGACAAAACTGAAGAGCAAGTCAGTTATGTCTAGCACAACTGG
TACAGTTTTCATCTAACATGATGATAAACAAGCTGATGAACAAGACTGCAAGAACATGTAAAGA
AGAATTTTAGGTCACATGTCAAATCATCTCTTCAAACTAAGAGTTAAATATTACGGTTATCCAA
TTTTCTTTCTTGGACAAAATTACTCCATGAAAAAATAATTTTGTACAGCTGCAAACAAAAGCAA
TCCAGGCTAAACATTATGGTTTTCAAATGAAATAAGTTAATAAATTCCAGGCTTACAAAACTCA
A

hide sequence

RefSeq Acc Id:

XM_005395401 ⟹ XP_005395458

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	4,352,406 - 4,367,807 (+)	NCBI

Sequence:

show sequence

AGCGAGTACACTGAACAGATACGACAACGACATGCTCTGCCAGGTCACAAGCAAATGAGAGGTA
AGAAACGGGAAGGAGTCAACTTTGGCTTTGAGTGTCTGACCTGGGTACAATTCCTTAAAAAAAG
AGACGACCAGCTTAGCTACTGACCATGGACTGAATCACAGAAAACTGGAACTGGACTGAATCAC
AGAAAAACGGCGAATGGCTTTCTCTTATAGGATGTCTGAACACAGCAAAATTCCCAAGCATGTT
TTGCAGAGTACACTTCATGGCTTAATCTCTTCTAACTGGTCTGGATTTCAGAAAGGATCAATAC
CAGAGGAAATGAAACAGACTGTTGAGGAACAGGGAAATAAGCCGCACTGGGCAGCTCTTCTGAT
ACTCATGGTGATAATACCAACCATTGGTGGAAACATCCTTGTTATTCTGGCTGTTTCACTGGAG
AAAAAGCTGCAGTACGCTACCAATTACTTTCTTATGTCCTTGGCGGTGGCTGATTTGCTGGTTG
GATTGTTTGTGATGCCAATTGCACTCTTGACAATAATGTTTGAGGCTATGTGGCCCCTCCCACT
TGTTCTGTGTCCTGCCTGGTTGTTTCTTGATGTTCTCTTTTCAACTGCATCCATCTTACACCTC
TGTGCCATTTCAGTGGACCGCTACATAGCCATCAAAAAGCCAATCCAGGCCAATCAATATAACT
CCCGAGCTACTGCACTCATCAAGATTACAGTGGTGTGGTTAATTTCAATAGGCATTGCCATTCC
AGTCCCTATTAAAGGGATAGATACTGATGTGCCTAACCCTAACAATATCACCTGTGCACTGACA
AAGGAGCGTTTTGGCAATTTCATGCTTTTTGGCTCCCTTGCTGCCTTCTTCACACCTCTTGCAA
TCATGATTGTCACCTACTTTCTCACCATCCATGCTCTACAGAAGAAAGCTTACTTGGTCAAAAA
CAAGGCACCTCAGCGTCTCCCATGGCTGAATGTGTCCACAGTATTTCAAAGAGATGAAACTCCC
TGCTCATCACCCGAGAAGGCGGCAATGCTGGGTGGTTCTCACAAGAACAAAACTCTGCCCAACT
CAAGTGATGAAACCCTCACGCGACGGATGTCCACAACTGGAAAAAAGTCTGCCCAAACTATTTC
TAATGAGCAGAGAGCCTCAAAGGTCCTTGGAATTGTATTTTTCCTCTTTTTGCTTATGTGGTGC
CCTTTTTTTATTACAAATATTACTTTAGCTTTGTGTGACTCCTGCAACCAGACTACTCTTAAAA
TGCTCCTGGAGATTTTTGTGTGGATAGGCTACATTTCCTCTGGGGTGAATCCTTTGGTCTATAC
TCTCTTCAACAAGACATTTCGGGATGCATTTGGTCGATATATCACCTGCAATTACCAGGCTACA
AAGTCAGCAAAAACTGTTAGAAAATGCTCCGGTAAGGTCTACTTCCGGAATCCGATGAAAGAGA
ACTCCAAATTTTTCACAAAACGTGGAATGCGAAATGGGGTTAATCCTACCATGTACCAGAGCCC
AAAGAGGCTCCGAAACTCAACCATTCAGTCTTCATCAGTCATTCCACTAGACACTCTTCTCCTC
ACTGAAAATGAAGGTGACAAAACTGAAGAGCAAGTCAGTTATGTCTAGCACAACTGGTACAGTT
TTCATCTAACATGATGATAAACAAGCTGATGAACAAGACTGCAAGAACATGTAAAGAAGAATTT
TAGGTCACATGTCAAATCATCTCTTCAAACTAAGAGTTAAATATTACGGTTATCCAATTTTCTT
TCTTGGACAAAATTACTCCATGAAAAAATAATTTTGTACAGCTGCAAACAAAAGCAATCCAGGC
TAAACATTATGGTTTTCAAATGAAATAAGTTAATAAATTCCAGGCTTACAAAACTCAA

hide sequence

RefSeq Acc Id:

XM_005395402 ⟹ XP_005395459

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	4,352,386 - 4,367,807 (+)	NCBI

Sequence:

show sequence

TTCAGCCACAGCCGCAAGCAAGCGAGTACACTGAACAGATACGACAACGACATGCTCTGCCAGG
TCACAAGCAAATGAGAGAAAGGATCAATACCAGAGGAAATGAAACAGACTGTTGAGGAACAGGG
AAATAAGCCGCACTGGGCAGCTCTTCTGATACTCATGGTGATAATACCAACCATTGGTGGAAAC
ATCCTTGTTATTCTGGCTGTTTCACTGGAGAAAAAGCTGCAGTACGCTACCAATTACTTTCTTA
TGTCCTTGGCGGTGGCTGATTTGCTGGTTGGATTGTTTGTGATGCCAATTGCACTCTTGACAAT
AATGTTTGAGGCTATGTGGCCCCTCCCACTTGTTCTGTGTCCTGCCTGGTTGTTTCTTGATGTT
CTCTTTTCAACTGCATCCATCTTACACCTCTGTGCCATTTCAGTGGACCGCTACATAGCCATCA
AAAAGCCAATCCAGGCCAATCAATATAACTCCCGAGCTACTGCACTCATCAAGATTACAGTGGT
GTGGTTAATTTCAATAGGCATTGCCATTCCAGTCCCTATTAAAGGGATAGATACTGATGTGCCT
AACCCTAACAATATCACCTGTGCACTGACAAAGGAGCGTTTTGGCAATTTCATGCTTTTTGGCT
CCCTTGCTGCCTTCTTCACACCTCTTGCAATCATGATTGTCACCTACTTTCTCACCATCCATGC
TCTACAGAAGAAAGCTTACTTGGTCAAAAACAAGGCACCTCAGCGTCTCCCATGGCTGAATGTG
TCCACAGTATTTCAAAGAGATGAAACTCCCTGCTCATCACCCGAGAAGGCGGCAATGCTGGGTG
GTTCTCACAAGAACAAAACTCTGCCCAACTCAAGTGATGAAACCCTCACGCGACGGATGTCCAC
AACTGGAAAAAAGTCTGCCCAAACTATTTCTAATGAGCAGAGAGCCTCAAAGGTCCTTGGAATT
GTATTTTTCCTCTTTTTGCTTATGTGGTGCCCTTTTTTTATTACAAATATTACTTTAGCTTTGT
GTGACTCCTGCAACCAGACTACTCTTAAAATGCTCCTGGAGATTTTTGTGTGGATAGGCTACAT
TTCCTCTGGGGTGAATCCTTTGGTCTATACTCTCTTCAACAAGACATTTCGGGATGCATTTGGT
CGATATATCACCTGCAATTACCAGGCTACAAAGTCAGCAAAAACTGTTAGAAAATGCTCCGGTA
AGGTCTACTTCCGGAATCCGATGAAAGAGAACTCCAAATTTTTCACAAAACGTGGAATGCGAAA
TGGGGTTAATCCTACCATGTACCAGAGCCCAAAGAGGCTCCGAAACTCAACCATTCAGTCTTCA
TCAGTCATTCCACTAGACACTCTTCTCCTCACTGAAAATGAAGGTGACAAAACTGAAGAGCAAG
TCAGTTATGTCTAGCACAACTGGTACAGTTTTCATCTAACATGATGATAAACAAGCTGATGAAC
AAGACTGCAAGAACATGTAAAGAAGAATTTTAGGTCACATGTCAAATCATCTCTTCAAACTAAG
AGTTAAATATTACGGTTATCCAATTTTCTTTCTTGGACAAAATTACTCCATGAAAAAATAATTT
TGTACAGCTGCAAACAAAAGCAATCCAGGCTAAACATTATGGTTTTCAAATGAAATAAGTTAAT
AAATTCCAGGCTTACAAAACTCAA

hide sequence

RefSeq Acc Id:

XM_013519961 ⟹ XP_013375415

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955453	4,352,278 - 4,367,807 (+)	NCBI

Sequence:

show sequence

ATCAAAGAGGAAATAACCTCGCTGGCAAGCTTACAGCTACACGGCACGTTGTTTCACTGTTTGC
AAGTGCCGTGCTGGAGGCTCCAAGTGAGTCAATGGGAGGAGGACTTCAGCCACAGCCGCAAGCA
AGCGAGTACACTGAACAGATACGACAACGACATGCTCTGCCAGGTCACAAGCAAATGAGAGGTA
AGAAACGGAAAGGATCAATACCAGAGGAAATGAAACAGACTGTTGAGGAACAGGGAAATAAGCC
GCACTGGGCAGCTCTTCTGATACTCATGGTGATAATACCAACCATTGGTGGAAACATCCTTGTT
ATTCTGGCTGTTTCACTGGAGAAAAAGCTGCAGTACGCTACCAATTACTTTCTTATGTCCTTGG
CGGTGGCTGATTTGCTGGTTGGATTGTTTGTGATGCCAATTGCACTCTTGACAATAATGTTTGA
GGCTATGTGGCCCCTCCCACTTGTTCTGTGTCCTGCCTGGTTGTTTCTTGATGTTCTCTTTTCA
ACTGCATCCATCTTACACCTCTGTGCCATTTCAGTGGACCGCTACATAGCCATCAAAAAGCCAA
TCCAGGCCAATCAATATAACTCCCGAGCTACTGCACTCATCAAGATTACAGTGGTGTGGTTAAT
TTCAATAGGCATTGCCATTCCAGTCCCTATTAAAGGGATAGATACTGATGTGCCTAACCCTAAC
AATATCACCTGTGCACTGACAAAGGAGCGTTTTGGCAATTTCATGCTTTTTGGCTCCCTTGCTG
CCTTCTTCACACCTCTTGCAATCATGATTGTCACCTACTTTCTCACCATCCATGCTCTACAGAA
GAAAGCTTACTTGGTCAAAAACAAGGCACCTCAGCGTCTCCCATGGCTGAATGTGTCCACAGTA
TTTCAAAGAGATGAAACTCCCTGCTCATCACCCGAGAAGGCGGCAATGCTGGGTGGTTCTCACA
AGAACAAAACTCTGCCCAACTCAAGTGATGAAACCCTCACGCGACGGATGTCCACAACTGGAAA
AAAGTCTGCCCAAACTATTTCTAATGAGCAGAGAGCCTCAAAGGTCCTTGGAATTGTATTTTTC
CTCTTTTTGCTTATGTGGTGCCCTTTTTTTATTACAAATATTACTTTAGCTTTGTGTGACTCCT
GCAACCAGACTACTCTTAAAATGCTCCTGGAGATTTTTGTGTGGATAGGCTACATTTCCTCTGG
GGTGAATCCTTTGGTCTATACTCTCTTCAACAAGACATTTCGGGATGCATTTGGTCGATATATC
ACCTGCAATTACCAGGCTACAAAGTCAGCAAAAACTGTTAGAAAATGCTCCGGTAAGGTCTACT
TCCGGAATCCGATGAAAGAGAACTCCAAATTTTTCACAAAACGTGGAATGCGAAATGGGGTTAA
TCCTACCATGTACCAGAGCCCAAAGAGGCTCCGAAACTCAACCATTCAGTCTTCATCAGTCATT
CCACTAGACACTCTTCTCCTCACTGAAAATGAAGGTGACAAAACTGAAGAGCAAGTCAGTTATG
TCTAGCACAACTGGTACAGTTTTCATCTAACATGATGATAAACAAGCTGATGAACAAGACTGCA
AGAACATGTAAAGAAGAATTTTAGGTCACATGTCAAATCATCTCTTCAAACTAAGAGTTAAATA
TTACGGTTATCCAATTTTCTTTCTTGGACAAAATTACTCCATGAAAAAATAATTTTGTACAGCT
GCAAACAAAAGCAATCCAGGCTAAACATTATGGTTTTCAAATGAAATAAGTTAATAAATTCCAG
GCTTACAAAACTCAA

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Protein Sequences


Protein RefSeqs	XP_005395457	(Get FASTA)	NCBI Sequence Viewer
	XP_005395458	(Get FASTA)	NCBI Sequence Viewer
	XP_005395459	(Get FASTA)	NCBI Sequence Viewer
	XP_013375415	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000017042
	ENSCLAP00000017042.1

RefSeq Acc Id:

XP_005395459 ⟸ XM_005395402

- Peptide Label:

isoform X3

- Sequence:

show sequence

MKQTVEEQGNKPHWAALLILMVIIPTIGGNILVILAVSLEKKLQYATNYFLMSLAVADLLVGLF
VMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFSTASILHLCAISVDRYIAIKKPIQANQYNSRA
TALIKITVVWLISIGIAIPVPIKGIDTDVPNPNNITCALTKERFGNFMLFGSLAAFFTPLAIMI
VTYFLTIHALQKKAYLVKNKAPQRLPWLNVSTVFQRDETPCSSPEKAAMLGGSHKNKTLPNSSD
ETLTRRMSTTGKKSAQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLALCDSCNQTTLKMLL
EIFVWIGYISSGVNPLVYTLFNKTFRDAFGRYITCNYQATKSAKTVRKCSGKVYFRNPMKENSK
FFTKRGMRNGVNPTMYQSPKRLRNSTIQSSSVIPLDTLLLTENEGDKTEEQVSYV

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RefSeq Acc Id:	XP_005395457 ⟸ XM_005395400
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2VKN7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAFSYRMSEHSKIPKHVLQSTLHGLISSNWSGFQKGSIPEEMKQTVEEQGNKPHWAALLILMVI IPTIGGNILVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCP AWLFLDVLFSTASILHLCAISVDRYIAIKKPIQANQYNSRATALIKITVVWLISIGIAIPVPIK GIDTDVPNPNNITCALTKERFGNFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAYLVKNKAPQ RLPWLNVSTVFQRDETPCSSPEKAAMLGGSHKNKTLPNSSDETLTRRMSTTGKKSAQTISNEQR ASKVLGIVFFLFLLMWCPFFITNITLALCDSCNQTTLKMLLEIFVWIGYISSGVNPLVYTLFNK TFRDAFGRYITCNYQATKSAKTVRKCSGKVYFRNPMKENSKFFTKRGMRNGVNPTMYQSPKRLR NSTIQSSSVIPLDTLLLTENEGDKTEEQVSYV hide sequence

RefSeq Acc Id:	XP_005395458 ⟸ XM_005395401
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2VKN7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAFSYRMSEHSKIPKHVLQSTLHGLISSNWSGFQKGSIPEEMKQTVEEQGNKPHWAALLILMVI IPTIGGNILVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLCP AWLFLDVLFSTASILHLCAISVDRYIAIKKPIQANQYNSRATALIKITVVWLISIGIAIPVPIK GIDTDVPNPNNITCALTKERFGNFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAYLVKNKAPQ RLPWLNVSTVFQRDETPCSSPEKAAMLGGSHKNKTLPNSSDETLTRRMSTTGKKSAQTISNEQR ASKVLGIVFFLFLLMWCPFFITNITLALCDSCNQTTLKMLLEIFVWIGYISSGVNPLVYTLFNK TFRDAFGRYITCNYQATKSAKTVRKCSGKVYFRNPMKENSKFFTKRGMRNGVNPTMYQSPKRLR NSTIQSSSVIPLDTLLLTENEGDKTEEQVSYV hide sequence

RefSeq Acc Id:

XP_013375415 ⟸ XM_013519961

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGGGLQPQPQASEYTEQIRQRHALPGHKQMRGKKRKGSIPEEMKQTVEEQGNKPHWAALLILMV
IIPTIGGNILVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPLPLVLC
PAWLFLDVLFSTASILHLCAISVDRYIAIKKPIQANQYNSRATALIKITVVWLISIGIAIPVPI
KGIDTDVPNPNNITCALTKERFGNFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAYLVKNKAP
QRLPWLNVSTVFQRDETPCSSPEKAAMLGGSHKNKTLPNSSDETLTRRMSTTGKKSAQTISNEQ
RASKVLGIVFFLFLLMWCPFFITNITLALCDSCNQTTLKMLLEIFVWIGYISSGVNPLVYTLFN
KTFRDAFGRYITCNYQATKSAKTVRKCSGKVYFRNPMKENSKFFTKRGMRNGVNPTMYQSPKRL
RNSTIQSSSVIPLDTLLLTENEGDKTEEQVSYV

hide sequence

Ensembl Acc Id:

ENSCLAP00000017042 ⟸ ENSCLAT00000017209

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011693	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000017209	ENTREZGENE
	ENSCLAT00000017209.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	5HT2B_rcpt	UniProtKB/TrEMBL
	5HT_rcpt	UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
NCBI Gene	Htr2b	ENTREZGENE
PANTHER	5-HYDROXYTRYPTAMINE RECEPTOR	UniProtKB/TrEMBL
	PTHR24247:SF31	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	5HT2BRECEPTR	UniProtKB/TrEMBL
	5HTRECEPTOR	UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C2VKN7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Htr2b	5-hydroxytryptamine receptor 2B		5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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