GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gja1 | increases expression | ISO | Gja1 (Mus musculus) | 6480464 | CTD | Vincristine results in increased expression of GJA1 mRNA; Vincristine results in increased expression of GJA1 protein | PMID:34286406 | Gja1 | multiple interactions | ISO | Gja1 (Mus musculus) | 6480464 | CTD | Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; gap 27 peptide inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; gap 27 peptide inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL1B protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL6 protein]; KN 62 inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; zinc chloride inhibits the reaction [Vincristine results in increased expression of GJA1 protein] | PMID:34286406 | |
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