CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | vincristine |
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Accession: | CHEBI:28445
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browse the term
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Definition: | A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. |
Synonyms: | related_synonym: | 22-Oxovincaleukoblastine; 22-oxo-vincaleukoblastine; Formula=C46H56N4O10; InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1; InChIKey=OGWKCGZFUXNPDA-XQKSVPLYSA-N; SMILES=[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C=O)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@@H]2C[N@](CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC; leucristine; leurocristine; oncovin; vincristin; vinkristin |
| alt_id: | CHEBI:27289; CHEBI:9987 |
| xref: | Beilstein:4779289; CAS:57-22-7; DrugBank:DB00541; Drug_Central:2825; HMDB:HMDB0014681; KEGG:C07204; KEGG:D08679; KNApSAcK:C00001783 |
| xref_mesh: | MESH:D014750 |
| xref: | MetaCyc:CPD-19894; PMID:18520608; PMID:30277559; PMID:30429697; PMID:30599272; PMID:30604513; PMID:30657998; PMID:31048222; PMID:31161774; PMID:31214762; PMID:31296986; Wikipedia:Vincristine |
| cyclic_relationship: | is_conjugate_base_of CHEBI:143658 |
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Aamdc |
adipogenesis associated, Mth938 domain containing |
increases expression |
ISO |
Vincristine results in increased expression of AAMDC mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:162,519,513...162,549,211
Ensembl chr 1:162,519,521...162,533,893
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Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA1 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
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Abca12 |
ATP binding cassette subfamily A member 12 |
increases expression multiple interactions |
ISO |
Vincristine results in increased expression of ABCA12 mRNA [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA12 mRNA |
CTD |
PMID:19944135 PMID:23649840 |
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NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028
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Abca4 |
ATP binding cassette subfamily A member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA4 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 2:225,645,539...225,783,288
Ensembl chr 2:225,645,568...225,783,287
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Abca5 |
ATP binding cassette subfamily A member 5 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA5 mRNA |
CTD |
PMID:19944135 |
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NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
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Abca8 |
ATP binding cassette subfamily A member 8 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA8 mRNA |
CTD |
PMID:19944135 |
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NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
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Abcb1a |
ATP binding cassette subfamily B member 1A |
affects response to substance increases expression multiple interactions increases transport decreases uptake decreases response to substance affects uptake |
ISO EXP |
ABCB1 protein affects the susceptibility to Vincristine Vincristine results in increased expression of ABCB1A mRNA Vincristine results in increased expression of ABCB1 protein [Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine; [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB1 mRNA; [Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine] ABCB1 protein results in decreased uptake of Vincristine ABCB1 protein affects the uptake of Vincristine |
CTD |
PMID:7905786 PMID:10617675 PMID:11792417 PMID:11934808 PMID:15239124 PMID:15645438 PMID:16038730 PMID:16221289 PMID:16316932 PMID:16925584 PMID:19944135 PMID:20041327 PMID:21344920 PMID:21833476 PMID:25058526 |
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NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
affects uptake |
EXP |
ABCB1B protein affects the uptake of Vincristine |
CTD |
PMID:11934808 |
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NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
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Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB4 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
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Abcb6 |
ATP binding cassette subfamily B member 6 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB6 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
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Abcc1 |
ATP binding cassette subfamily C member 1 |
increases response to substance increases expression multiple interactions decreases response to substance affects transport affects response to substance affects export |
ISO EXP |
ABCC1 gene SNP results in increased susceptibility to Vincristine Vincristine results in increased expression of ABCC1 mRNA [Genistein results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Indomethacin results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [verlukast results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine ABCC1 protein results in decreased susceptibility to Vincristine; ABCC1 results in decreased susceptibility to Vincristine [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine; Buthionine Sulfoximine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Doxorubicin inhibits the reaction [ABCC1 protein affects the transport of Vincristine]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Quercetin promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon]; Vincristine inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; zafirlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine] ABCC1 protein affects the transport of Vincristine; ABCC1 protein mutant form affects the transport of Vincristine ABCC1 protein affects the susceptibility to Vincristine |
CTD |
PMID:7954421 PMID:8649356 PMID:8968083 PMID:10348353 PMID:10685512 PMID:10900222 PMID:11278867 PMID:11306701 PMID:11778547 PMID:12067707 PMID:12731862 PMID:12893836 PMID:15044619 PMID:15180633 PMID:15581632 PMID:15896345 PMID:16042792 PMID:16221289 PMID:19232821 PMID:19944135 PMID:20864405 PMID:21918036 PMID:22095822 |
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NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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Abcc10 |
ATP binding cassette subfamily C member 10 |
multiple interactions decreases response to substance |
ISO |
4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine]; Imatinib Mesylate inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:19841739 |
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NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
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Abcc2 |
ATP binding cassette subfamily C member 2 |
affects export multiple interactions decreases response to substance |
ISO |
ABCC2 protein affects the export of Vincristine [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC2 mRNA; ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine; myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:15896345 PMID:19944135 PMID:22095822 |
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NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC3 mRNA |
CTD |
PMID:19944135 |
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NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
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Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC4 mRNA |
CTD |
PMID:19944135 |
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NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
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Abcc5 |
ATP binding cassette subfamily C member 5 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCC5 mRNA |
CTD |
PMID:19944135 |
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NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
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Abcc6 |
ATP binding cassette subfamily C member 6 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC6 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
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Abcd3 |
ATP binding cassette subfamily D member 3 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCD3 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
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Abcg1 |
ATP binding cassette subfamily G member 1 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG1 mRNA |
CTD |
PMID:19944135 |
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NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
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Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions |
ISO |
[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCG2 mRNA |
CTD |
PMID:19944135 PMID:21833476 |
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NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
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Abcg4 |
ATP binding cassette subfamily G member 4 |
multiple interactions |
ISO |
[Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG4 mRNA |
CTD |
PMID:19944135 |
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NCBI chr 8:48,604,915...48,626,219
Ensembl chr 8:48,606,403...48,619,592
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Abhd11 |
abhydrolase domain containing 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of ABHD11 mRNA |
CTD |
PMID:23649840 |
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NCBI chr12:24,722,277...24,725,760
Ensembl chr12:24,722,283...24,724,997
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Abtb2 |
ankyrin repeat and BTB domain containing 2 |
increases expression |
ISO |
Vincristine results in increased expression of ABTB2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:93,494,706...93,648,750
Ensembl chr 3:93,495,106...93,647,721
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Acad9 |
acyl-CoA dehydrogenase family, member 9 |
decreases expression |
ISO |
Vincristine results in decreased expression of ACAD9 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:122,782,051...122,806,166
Ensembl chr 2:122,782,060...122,805,768
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Ache |
acetylcholinesterase |
decreases expression multiple interactions |
EXP |
Vincristine results in decreased expression of ACHE protein xaliproden inhibits the reaction [Vincristine results in decreased expression of ACHE protein] |
CTD |
PMID:8413926 |
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NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
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Ackr3 |
atypical chemokine receptor 3 |
increases expression |
ISO |
Vincristine results in increased expression of ACKR3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
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Actr2 |
actin related protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of ACTR2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
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Adat2 |
adenosine deaminase, tRNA-specific 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ADAT2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:7,726,447...7,743,112
Ensembl chr 1:7,726,529...7,742,484
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Adgrf4 |
adhesion G protein-coupled receptor F4 |
increases expression |
ISO |
Vincristine results in increased expression of ADGRF4 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:20,951,249...20,982,493
Ensembl chr 9:20,951,260...20,982,487
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Adrb1 |
adrenoceptor beta 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ADRB1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
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Adrb2 |
adrenoceptor beta 2 |
increases response to substance |
ISO |
ADRB2 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
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NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
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Agbl3 |
AGBL carboxypeptidase 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of AGBL3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:62,293,158...62,377,740
Ensembl chr 4:62,299,044...62,376,533
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Ahsa2 |
activator of HSP90 ATPase homolog 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of AHSA2P mRNA |
CTD |
PMID:23649840 |
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NCBI chr14:108,262,795...108,274,000
Ensembl chr14:108,265,207...108,273,938
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Aim2 |
absent in melanoma 2 |
increases expression |
ISO |
Vincristine results in increased expression of AIM2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
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Ak1 |
adenylate kinase 1 |
decreases expression |
EXP |
Vincristine results in decreased expression of AK1 mRNA |
CTD |
PMID:20624997 |
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NCBI chr 3:11,652,143...11,659,135
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Ak3 |
adenylate kinase 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of AK3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
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Akap10 |
A-kinase anchoring protein 10 |
increases expression |
ISO |
Vincristine results in increased expression of AKAP10 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:48,150,902...48,210,074
Ensembl chr10:48,150,902...48,210,074
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Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
Vincristine inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein] Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]] |
CTD |
PMID:16740780 PMID:18590705 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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Aldoc |
aldolase, fructose-bisphosphate C |
decreases expression |
ISO |
Vincristine results in decreased expression of ALDOC mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
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Alms1 |
ALMS1, centrosome and basal body associated protein |
decreases expression |
ISO |
Vincristine results in decreased expression of ALMS1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
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Alpk2 |
alpha-kinase 2 |
increases expression |
ISO |
Vincristine results in increased expression of ALPK2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
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Amh |
anti-Mullerian hormone |
decreases secretion |
ISO |
Vincristine results in decreased secretion of AMH protein |
CTD |
PMID:30657998 |
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NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
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Anapc5 |
anaphase-promoting complex subunit 5 |
increases expression |
ISO |
Vincristine results in increased expression of ANAPC5 mRNA |
CTD |
PMID:23649840 |
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NCBI chr12:39,209,134...39,242,696
Ensembl chr12:39,209,129...39,242,690
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Ankdd1a |
ankyrin repeat and death domain containing 1A |
decreases expression |
ISO |
Vincristine results in decreased expression of ANKDD1A mRNA |
CTD |
PMID:23649840 |
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NCBI chr 8:71,034,630...71,057,265
Ensembl chr 8:71,035,309...71,055,969
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Ankhd1 |
ankyrin repeat and KH domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of ANKHD1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:29,386,906...29,485,611
Ensembl chr18:29,386,809...29,492,718
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Ankra2 |
ankyrin repeat family A member 2 |
increases expression |
ISO |
Vincristine results in increased expression of ANKRA2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr X:82,407,601...82,418,229
Ensembl chr X:82,407,598...82,418,425
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Ankrd13c |
ankyrin repeat domain 13C |
decreases expression |
ISO |
Vincristine results in decreased expression of ANKRD13C mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:264,785,379...264,833,283
Ensembl chr 2:264,786,242...264,833,283
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Ankrd33b |
ankyrin repeat domain 33B |
increases expression |
ISO |
Vincristine results in increased expression of ANKRD33B mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:84,361,061...84,436,912
Ensembl chr 2:84,361,061...84,437,084
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Ankrd37 |
ankyrin repeat domain 37 |
decreases expression |
ISO |
Vincristine results in decreased expression of ANKRD37 mRNA |
CTD |
PMID:23649840 |
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NCBI chr16:49,463,016...49,465,905
Ensembl chr16:49,462,889...49,465,888
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Anp32e |
acidic nuclear phosphoprotein 32 family member E |
decreases expression |
ISO |
Vincristine results in decreased expression of ANP32E mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:198,040,573...198,057,005
Ensembl chr 2:198,040,536...198,057,003
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Anxa1 |
annexin A1 |
increases expression |
ISO |
Vincristine results in increased expression of ANXA1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
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Anxa2 |
annexin A2 |
increases expression |
ISO |
Vincristine results in increased expression of ANXA2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
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Ap1s2 |
adaptor related protein complex 1 subunit sigma 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of AP1S2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr X:32,329,883...32,376,301
Ensembl chr X:32,329,598...32,355,307
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G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of APEX2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr X:23,146,085...23,166,676
Ensembl chr X:23,146,085...23,166,675
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G |
Apln |
apelin |
decreases expression |
EXP |
Vincristine results in decreased expression of APLN mRNA |
CTD |
PMID:20624997 |
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NCBI chr X:134,856,719...134,866,210
Ensembl chr X:134,856,726...134,866,210
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G |
Apod |
apolipoprotein D |
increases expression |
ISO |
Vincristine results in increased expression of APOD mRNA |
CTD |
PMID:23649840 |
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NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
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G |
Apold1 |
apolipoprotein L domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of APOLD1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023
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G |
Aqp9 |
aquaporin 9 |
increases expression |
ISO |
Vincristine results in increased expression of AQP9 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
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G |
Arap2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARAP2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr14:48,726,033...48,922,809
Ensembl chr14:48,726,045...48,922,983
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G |
Arf1 |
ADP-ribosylation factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of ARF1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
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G |
Arhgap15 |
Rho GTPase activating protein 15 |
increases expression |
ISO |
Vincristine results in increased expression of ARHGAP15 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:28,626,987...29,236,225
Ensembl chr 3:28,627,084...29,236,219
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G |
Arhgap18 |
Rho GTPase activating protein 18 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARHGAP18 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
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G |
Arhgap5 |
Rho GTPase activating protein 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARHGAP5 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
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G |
Arhgef6 |
Rac/Cdc42 guanine nucleotide exchange factor 6 |
increases expression |
ISO |
Vincristine results in increased expression of ARHGEF6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:159,722,031...159,841,344
Ensembl chr X:159,723,866...159,841,072
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G |
Arhgef7 |
Rho guanine nucleotide exchange factor 7 |
increases expression |
ISO |
Vincristine results in increased expression of ARHGEF7 mRNA |
CTD |
PMID:23649840 |
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NCBI chr16:83,006,732...83,117,065
Ensembl chr16:83,006,718...83,132,785
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G |
Arid2 |
AT-rich interaction domain 2 |
increases expression |
ISO |
Vincristine results in increased expression of ARID2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:137,680,564...137,798,329
Ensembl chr 7:137,680,530...137,795,655
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G |
Arid4b |
AT-rich interaction domain 4B |
increases expression |
ISO |
Vincristine results in increased expression of ARID4B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:53,831,353...53,955,897
Ensembl chr17:53,833,023...53,915,076
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G |
Arl5a |
ADP-ribosylation factor like GTPase 5A |
decreases expression |
ISO |
Vincristine results in decreased expression of ARL5A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:37,922,544...37,947,434
Ensembl chr 3:37,924,793...37,947,283
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G |
Arl5b |
ADP-ribosylation factor like GTPase 5B |
increases expression |
ISO |
Vincristine results in increased expression of ARL5B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:82,065,893...82,092,693
Ensembl chr17:82,065,937...82,091,362
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G |
Arl6ip1 |
ADP-ribosylation factor like GTPase 6 interacting protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARL6IP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
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G |
Armc8 |
armadillo repeat containing 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of ARMC8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:107,723,359...107,819,208
Ensembl chr 8:107,723,359...107,819,050
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G |
Aspm |
assembly factor for spindle microtubules |
increases expression |
ISO |
Vincristine results in increased expression of ASPM mRNA |
CTD |
PMID:17374387 |
|
NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
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G |
Asxl1 |
ASXL transcriptional regulator 1 |
increases expression |
ISO |
Vincristine results in increased expression of ASXL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452
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G |
Atad2 |
ATPase family, AAA domain containing 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ATAD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
Vincristine results in increased expression of ATF3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
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G |
Atf5 |
activating transcription factor 5 |
increases expression |
ISO |
Vincristine results in increased expression of ATF5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
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G |
Atp2b4 |
ATPase plasma membrane Ca2+ transporting 4 |
increases expression |
ISO |
Vincristine results in increased expression of ATP2B4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
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G |
Atp5f1c |
ATP synthase F1 subunit gamma |
decreases expression |
ISO |
Vincristine results in decreased expression of ATP5F1C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
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G |
Atp6v0e1 |
ATPase H+ transporting V0 subunit e1 |
increases expression |
ISO |
Vincristine results in increased expression of ATP6V0E1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:16,769,857...16,792,930
Ensembl chr10:16,769,666...16,792,909
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G |
Atp7a |
ATPase copper transporting alpha |
decreases response to substance |
ISO |
ATP7A protein results in decreased susceptibility to Vincristine |
CTD |
PMID:17510416 |
|
NCBI chr X:77,076,085...77,193,644
Ensembl chr X:77,076,106...77,193,644
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G |
Atp8a1 |
ATPase phospholipid transporting 8A1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ATP8A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:41,972,398...42,210,555
Ensembl chr14:42,015,347...42,206,311
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G |
Aurka |
aurora kinase A |
increases response to substance increases expression |
ISO |
AURKA gene SNP results in increased susceptibility to Vincristine Vincristine results in increased expression of AURKA mRNA |
CTD |
PMID:17374387 PMID:20864405 |
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NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
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G |
Aurkb |
aurora kinase B |
decreases expression |
ISO |
Vincristine results in decreased expression of AURKB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
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G |
Avp |
arginine vasopressin |
increases expression |
ISO |
Vincristine results in increased expression of AVP protein |
CTD |
PMID:4356234 |
|
NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
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G |
B3galt6 |
Beta-1,3-galactosyltransferase 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of B3GALT6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:173,423,475...173,425,611
Ensembl chr 5:173,423,475...173,425,611
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G |
B3gnt5 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
increases expression |
ISO |
Vincristine results in increased expression of B3GNT5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:84,919,055...84,931,160
Ensembl chr11:84,919,066...84,931,160
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G |
Bak1 |
BCL2-antagonist/killer 1 |
affects response to substance |
ISO |
BAK1 protein affects the susceptibility to Vincristine |
CTD |
PMID:22178383 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
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G |
Bambi |
BMP and activin membrane-bound inhibitor |
increases expression |
ISO |
Vincristine results in increased expression of BAMBI mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
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G |
Bard1 |
BRCA1 associated RING domain 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BARD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:78,297,723...78,368,777
Ensembl chr 9:78,294,834...78,369,031
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G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of BASP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
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G |
Batf |
basic leucine zipper ATF-like transcription factor |
increases expression |
ISO |
Vincristine results in increased expression of BATF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:109,562,415...109,584,541
Ensembl chr 6:109,562,587...109,584,545
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G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression affects response to substance multiple interactions |
ISO |
Vincristine results in decreased expression of BAX mRNA BAX protein affects the susceptibility to Vincristine [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; Vincristine results in increased cleavage of and results in increased expression of BAX protein |
CTD |
PMID:9815696 PMID:15131059 PMID:16001973 PMID:22178383 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcat1 |
branched chain amino acid transaminase 1 |
increases expression |
ISO |
Vincristine results in increased expression of BCAT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases response to substance increases phosphorylation multiple interactions |
ISO |
BCL2 protein results in decreased susceptibility to Vincristine Vincristine results in increased phosphorylation of BCL2 protein [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [MIR497 results in decreased expression of BCL2 protein] which results in increased susceptibility to Vincristine; TYMP inhibits the reaction [Vincristine results in increased phosphorylation of BCL2 protein] |
CTD |
PMID:9815696 PMID:15907805 PMID:20162574 PMID:21182165 PMID:21258880 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2a1 |
BCL2-related protein A1 |
increases expression |
ISO |
Vincristine results in increased expression of BCL2A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression affects response to substance |
ISO |
Vincristine results in increased expression of BCL2L1 mRNA BCL2L1 protein affects the susceptibility to Vincristine |
CTD |
PMID:22178383 PMID:23649840 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
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G |
Bclaf1 |
BCL2-associated transcription factor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BCLAF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
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G |
Bcor |
BCL6 co-repressor |
increases expression |
ISO |
Vincristine results in increased expression of BCOR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:11,570,155...11,692,022
Ensembl chr X:11,648,989...11,691,099
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
EXP |
[HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Vincristine |
CTD |
PMID:17989505 |
|
NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
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G |
Bdkrb2 |
bradykinin receptor B2 |
multiple interactions |
EXP |
[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Vincristine |
CTD |
PMID:17989505 |
|
NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
Vincristine results in increased expression of BIRC2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Vincristine results in increased expression of BIRC3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
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G |
Blm |
BLM RecQ like helicase |
decreases expression |
ISO |
Vincristine results in decreased expression of BLM mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
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G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of BMP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
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G |
Bnip3 |
BCL2 interacting protein 3 |
decreases expression multiple interactions |
ISO |
Vincristine results in decreased expression of BNIP3 mRNA Vincristine affects the reaction [Valproic Acid affects the localization of BNIP3 protein] |
CTD |
PMID:23649840 PMID:25446377 |
|
NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
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G |
Bnip3l |
BCL2 interacting protein 3 like |
decreases expression |
ISO |
Vincristine results in decreased expression of BNIP3L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
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G |
Borcs7 |
BLOC-1 related complex subunit 7 |
increases expression |
ISO |
Vincristine results in increased expression of BORCS7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:266,451,021...266,464,903
Ensembl chr 1:266,451,021...266,464,903
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G |
Brip1 |
BRCA1 interacting protein C-terminal helicase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BRIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:73,507,009...73,632,742
Ensembl chr10:73,507,100...73,629,581
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G |
Brwd1 |
bromodomain and WD repeat domain containing 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of BRWD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:36,338,080...36,430,473
Ensembl chr11:36,337,635...36,430,413
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G |
Btg1 |
BTG anti-proliferation factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of BTG1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
|
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Vincristine results in increased expression of BTG2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
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G |
Btg4 |
BTG anti-proliferation factor 4 |
increases expression |
ISO |
Vincristine results in increased expression of BTG4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:55,408,917...55,508,100
Ensembl chr 8:55,504,359...55,508,259
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G |
Bub3 |
BUB3 mitotic checkpoint protein |
decreases expression |
ISO |
Vincristine results in decreased expression of BUB3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
|
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G |
C1galt1 |
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of C1GALT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:33,890,353...33,943,219
Ensembl chr 4:33,890,349...33,943,211
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G |
Cables2 |
Cdk5 and Abl enzyme substrate 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CABLES2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:175,630,266...175,644,994
Ensembl chr 3:175,631,881...175,644,988
|
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G |
Cacnb2 |
calcium voltage-gated channel auxiliary subunit beta 2 |
increases expression |
ISO |
Vincristine results in increased expression of CACNB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
|
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G |
Cald1 |
caldesmon 1 |
increases expression |
ISO |
Vincristine results in increased expression of CALD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
|
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G |
Calm2 |
calmodulin 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CALM2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
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G |
Calu |
calumenin |
increases expression |
ISO |
Vincristine results in increased expression of CALU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
|
|
G |
Camk2d |
calcium/calmodulin-dependent protein kinase II delta |
decreases expression |
ISO |
Vincristine results in decreased expression of CAMK2D mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
|
|
G |
Camkk1 |
calcium/calmodulin-dependent protein kinase kinase 1 |
increases response to substance |
ISO |
CAMKK1 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr10:59,585,023...59,608,180
Ensembl chr10:59,585,072...59,608,165
|
|
G |
Capg |
capping actin protein, gelsolin like |
increases expression |
ISO |
Vincristine results in increased expression of CAPG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
|
|
G |
Carhsp1 |
calcium regulated heat stable protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CARHSP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
|
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G |
Casp1 |
caspase 1 |
increases expression |
ISO |
Vincristine results in increased expression of CASP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
|
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions increases expression |
EXP |
Vincristine results in increased cleavage of CASP3 protein Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 mRNA]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 protein] Vincristine results in increased expression of CASP3 mRNA; Vincristine results in increased expression of CASP3 protein |
CTD |
PMID:20624997 PMID:29958920 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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Casp6 |
caspase 6 |
increases expression |
ISO |
Vincristine results in increased expression of CASP6 mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967 Ensembl chr 2:235,341,365...235,353,967
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Casp8 |
caspase 8 |
increases expression increases response to substance multiple interactions |
ISO |
Vincristine results in increased expression of CASP8 mRNA CASP8 protein results in increased susceptibility to Vincristine Vincristine results in increased expression of and results in increased cleavage of CASP8 protein |
CTD |
PMID:16001973 PMID:22010212 |
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NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
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G |
Cat |
catalase |
affects response to substance decreases expression multiple interactions |
ISO EXP |
CAT protein affects the susceptibility to Vincristine Vincristine results in decreased expression of CAT protein tetrahydrocurcumin inhibits the reaction [Vincristine results in decreased expression of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein] |
CTD |
PMID:11178967 PMID:24201307 PMID:25537132 PMID:26102012 |
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NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Cbx3 |
chromobox 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CBX3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:81,243,809...81,257,898
Ensembl chr 4:81,244,469...81,257,897
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G |
Cbx5 |
chromobox 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of CBX5 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
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G |
Ccar1 |
cell division cycle and apoptosis regulator 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCAR1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr20:32,373,443...32,416,044
Ensembl chr20:32,373,443...32,416,044
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G |
Ccdc12 |
coiled-coil domain containing 12 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC12 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 8:118,925,682...118,977,038
Ensembl chr 8:118,926,478...118,977,051
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G |
Ccdc186 |
coiled-coil domain containing 186 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC186 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:277,603,601...277,635,379
Ensembl chr 1:277,606,995...277,629,196
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G |
Ccdc198 |
coiled-coil domain containing 198 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC198 mRNA |
CTD |
PMID:23649840 |
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NCBI chr15:26,090,458...26,106,523
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G |
Ccdc32 |
coiled-coil domain containing 32 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCDC32 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:110,816,327...110,828,824
Ensembl chr 3:110,816,337...110,828,879
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G |
Ccdc82 |
coiled-coil domain containing 82 |
increases expression |
ISO |
Vincristine results in increased expression of CCDC82 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:11,888,460...11,927,920
Ensembl chr 8:11,888,591...11,927,919
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G |
Cchcr1 |
coiled-coil alpha-helical rod protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCHCR1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr20:3,730,968...3,745,721
Ensembl chr20:3,730,955...3,740,009
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
increases expression |
ISO |
Vincristine results in increased expression of CCL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO EXP |
Vincristine results in increased expression of CCL2 mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Vincristine results in increased expression of CCL20 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
ISO |
Vincristine results in increased expression of CCL22 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
Vincristine results in increased expression of CCL4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression |
ISO |
Vincristine results in increased expression of CCL5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
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G |
Ccn2 |
cellular communication network factor 2 |
decreases response to substance |
ISO |
CCN2 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:24154679 |
|
NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
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G |
Ccnb1 |
cyclin B1 |
affects response to substance increases expression |
ISO |
CCNB1 protein affects the susceptibility to Vincristine Vincristine results in increased expression of CCNB1 mRNA |
CTD |
PMID:22178383 PMID:23649840 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
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G |
Ccnb2 |
cyclin B2 |
increases expression |
ISO |
Vincristine results in increased expression of CCNB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:76,847,972...76,861,165
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G |
Ccne1 |
cyclin E1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCNE1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
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G |
Ccne2 |
cyclin E2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCNE2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
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G |
Ccnl1 |
cyclin L1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CCNL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838
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G |
Cd109 |
CD109 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD109 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:85,951,420...86,065,411
Ensembl chr 8:85,951,191...86,065,409
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G |
Cd14 |
CD14 molecule |
increases expression |
EXP |
Vincristine results in increased expression of CD14 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
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G |
Cd200 |
Cd200 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD200 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196
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G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD274 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
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G |
Cd36 |
CD36 molecule |
increases expression |
EXP |
Vincristine results in increased expression of CD36 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
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G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD40 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
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G |
Cd44 |
CD44 molecule (Indian blood group) |
increases expression |
ISO |
Vincristine results in increased expression of CD44 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
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G |
Cd48 |
Cd48 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD48 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
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G |
Cd55 |
CD55 molecule (Cromer blood group) |
increases expression |
ISO |
Vincristine results in increased expression of CD55 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
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G |
Cd69 |
Cd69 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD69 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
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G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD80 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
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G |
Cd83 |
CD83 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD83 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
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G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
Vincristine results in increased expression of CD86 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
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G |
Cdc42ep3 |
CDC42 effector protein 3 |
increases expression |
ISO |
Vincristine results in increased expression of CDC42EP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
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G |
Cdc42ep4 |
CDC42 effector protein 4 |
increases expression |
ISO |
Vincristine results in increased expression of CDC42EP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:102,244,680...102,269,272
Ensembl chr10:102,244,681...102,269,272
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G |
Cdc42se1 |
CDC42 small effector 1 |
increases expression |
ISO |
Vincristine results in increased expression of CDC42SE1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:196,402,837...196,410,664
Ensembl chr 2:196,402,837...196,410,659
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G |
Cdc6 |
cell division cycle 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDC6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
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G |
Cdca3 |
cell division cycle associated 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDCA3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
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G |
Cdca7 |
cell division cycle associated 7 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDCA7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:59,153,281...59,163,916
Ensembl chr 3:59,153,280...59,163,913
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G |
Cdh1 |
cadherin 1 |
increases expression |
ISO |
Vincristine results in increased expression of CDH1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
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G |
Cdk10 |
cyclin-dependent kinase 10 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:56,024,903...56,032,610
Ensembl chr19:56,024,903...56,032,605
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G |
Cdk19 |
cyclin-dependent kinase 19 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK19 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:45,458,499...45,598,799
Ensembl chr20:45,458,558...45,598,798
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G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CDK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
EXP ISO |
Vincristine results in increased expression of CDKN1A mRNA resveratrol inhibits the reaction [Vincristine results in increased expression of CDKN1A mRNA] |
CTD |
PMID:20624997 PMID:23649840 PMID:26055805 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases response to substance |
ISO |
CDKN2A protein results in increased susceptibility to Vincristine |
CTD |
PMID:16786135 |
|
NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
decreases expression |
ISO |
Vincristine results in decreased expression of CDKN2C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
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G |
Ceacam1 |
CEA cell adhesion molecule 1 |
increases expression |
ISO |
Vincristine results in increased expression of CEACAM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
Vincristine results in increased expression of CEBPB mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
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G |
Celf1 |
CUGBP, Elav-like family member 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CELF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:79,768,900...79,844,548
Ensembl chr 3:79,823,945...79,842,082
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G |
Cenpc |
centromere protein C |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:23,611,909...23,670,314
Ensembl chr14:23,611,735...23,670,475
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G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
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G |
Cenpi |
centromere protein I |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPI mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:105,147,045...105,198,798
Ensembl chr X:105,147,153...105,198,797
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G |
Cenpu |
centromere protein U |
decreases expression |
ISO |
Vincristine results in decreased expression of CENPU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:48,898,032...48,921,248
Ensembl chr16:48,897,982...48,921,242
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G |
Cep135 |
centrosomal protein 135 |
increases expression |
ISO |
Vincristine results in increased expression of CEP135 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:34,052,168...34,115,763
Ensembl chr14:34,051,003...34,115,273
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G |
Ces5a |
carboxylesterase 5A |
increases expression |
ISO |
Vincristine results in increased expression of CES5A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:12,097,529...12,136,579
Ensembl chr19:12,097,632...12,136,240
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
increases expression |
ISO |
Vincristine results in increased expression of CFLAR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
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G |
Chd1l |
chromodomain helicase DNA binding protein 1-like |
increases expression |
ISO |
Vincristine results in increased expression of CHD1L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:199,714,044...199,792,270
Ensembl chr 2:199,716,713...199,771,896
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G |
Chek2 |
checkpoint kinase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CHEK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
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G |
Chm |
CHM Rab escort protein |
increases expression |
ISO |
Vincristine results in increased expression of CHM mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:84,666,900...84,821,775
Ensembl chr X:84,666,900...84,821,775
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G |
Chml |
CHM like Rab escort protein |
decreases expression |
ISO |
Vincristine results in decreased expression of CHML mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:93,740,759...93,742,624
|
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G |
Chtf18 |
chromosome transmission fidelity factor 18 |
decreases expression |
ISO |
Vincristine results in decreased expression of CHTF18 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:15,090,762...15,098,825
Ensembl chr10:15,090,316...15,098,791
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G |
Ciapin1 |
cytokine induced apoptosis inhibitor 1 |
decreases response to substance |
ISO |
CIAPIN1 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:18389626 |
|
NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
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|
G |
Cirbp |
cold inducible RNA binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of CIRBP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
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|
G |
Clasp2 |
cytoplasmic linker associated protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of CLASP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
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G |
Clec2d |
C-type lectin domain family 2, member D |
decreases expression |
ISO |
Vincristine results in decreased expression of CLEC2D mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:162,278,252...162,302,881
Ensembl chr 4:162,292,305...162,302,156
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G |
Clic2 |
chloride intracellular channel 2 |
increases expression |
ISO |
Vincristine results in increased expression of CLIC2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:295,338...310,363
Ensembl chr20:295,250...310,380
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|
G |
Clspn |
claspin |
decreases expression |
ISO |
Vincristine results in decreased expression of CLSPN mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335
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|
G |
Cnksr2 |
connector enhancer of kinase suppressor of Ras 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of CNKSR2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:39,711,001...39,953,860
Ensembl chr X:39,711,201...39,951,847
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|
G |
Cnot3 |
CCR4-NOT transcription complex, subunit 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CNOT3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:64,130,823...64,147,066
Ensembl chr 1:64,130,908...64,147,251
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G |
Cnot6l |
CCR4-NOT transcription complex, subunit 6-like |
decreases expression |
ISO |
Vincristine results in decreased expression of CNOT6L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:15,059,101...15,148,255
Ensembl chr14:15,059,387...15,146,586
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Cntln |
centlein |
decreases expression |
ISO |
Vincristine results in decreased expression of CNTLN mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:103,251,986...103,367,088
Ensembl chr 5:103,251,986...103,366,264
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G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases response to substance |
ISO |
COL15A1 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
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NCBI chr 5:62,840,360...62,950,240
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G |
Col1a2 |
collagen type I alpha 2 chain |
increases response to substance |
ISO |
COL1A2 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
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NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
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G |
Col3a1 |
collagen type III alpha 1 chain |
decreases response to substance |
ISO |
COL3A1 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
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G |
Col5a2 |
collagen type V alpha 2 chain |
decreases response to substance |
ISO |
COL5A2 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
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G |
Comtd1 |
catechol-O-methyltransferase domain containing 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of COMTD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:2,631,529...2,634,640
Ensembl chr15:2,631,529...2,634,640
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G |
Cp |
ceruloplasmin |
increases expression |
EXP |
Vincristine results in increased expression of CP mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
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G |
Cpeb2 |
cytoplasmic polyadenylation element binding protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of CPEB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:72,327,929...72,382,519
Ensembl chr14:72,331,705...72,380,330
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G |
Cpne3 |
copine 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CPNE3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:33,525,307...33,574,610
Ensembl chr 5:33,528,154...33,574,596
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G |
Cpsf6 |
cleavage and polyadenylation specific factor 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of CPSF6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:60,385,688...60,417,661
Ensembl chr 7:60,385,688...60,416,925
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G |
Crebbp |
CREB binding protein |
increases expression |
ISO |
Vincristine results in increased expression of CREBBP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
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G |
Crebrf |
CREB3 regulatory factor |
increases expression |
ISO |
Vincristine results in increased expression of CREBRF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
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G |
Crebzf |
CREB/ATF bZIP transcription factor |
decreases expression |
ISO |
Vincristine results in decreased expression of CREBZF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:156,290,215...156,296,891
Ensembl chr 1:156,294,519...156,296,161
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G |
Crtap |
cartilage associated protein |
decreases expression |
ISO |
Vincristine results in decreased expression of CRTAP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:122,382,613...122,402,209
|
|
G |
Crtc3 |
CREB regulated transcription coactivator 3 |
increases expression |
ISO |
Vincristine results in increased expression of CRTC3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:142,398,248...142,500,562
Ensembl chr 1:142,393,207...142,500,383
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G |
Csad |
cysteine sulfinic acid decarboxylase |
decreases expression |
ISO |
Vincristine results in decreased expression of CSAD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
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G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
Vincristine results in increased expression of CSF2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
|
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G |
Csnk1a1 |
casein kinase 1, alpha 1 |
increases expression |
ISO |
Vincristine results in increased expression of CSNK1A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
|
|
G |
Csnk1g1 |
casein kinase 1, gamma 1 |
increases expression |
ISO |
Vincristine results in increased expression of CSNK1G1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:71,533,372...71,688,483
Ensembl chr 8:71,547,468...71,679,666
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G |
Csta |
cystatin A |
increases expression |
ISO |
Vincristine results in increased expression of CSTA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
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G |
Cstf1 |
cleavage stimulation factor subunit 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CSTF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:170,380,413...170,392,162
Ensembl chr 3:170,380,719...170,392,160
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G |
Ctc1 |
CST telomere replication complex component 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CTC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:55,596,172...55,616,873
Ensembl chr10:55,596,148...55,616,889
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G |
Cth |
cystathionine gamma-lyase |
increases expression |
ISO |
Vincristine results in increased expression of CTH mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
|
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G |
Ctnnal1 |
catenin alpha-like 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CTNNAL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
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|
G |
Ctnnb1 |
catenin beta 1 |
increases expression decreases response to substance |
ISO |
Vincristine results in increased expression of CTNNB1 mRNA CTNNB1 results in decreased susceptibility to Vincristine |
CTD |
PMID:22000491 PMID:23649840 |
|
NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
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G |
Cul4a |
cullin 4A |
increases expression |
ISO |
Vincristine results in increased expression of CUL4A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
Vincristine results in increased expression of CXCL10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
|
|
G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
increases expression |
ISO |
Vincristine results in increased expression of CXCL11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Vincristine results in increased expression of CXCL9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
increases expression |
ISO |
Vincristine results in increased expression of CYLD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
increases response to substance |
ISO |
CYP2C8 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr 1:147,236,480...147,307,988
|
|
G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
increases metabolic processing |
ISO |
CYP3A4 protein results in increased metabolism of Vincristine |
CTD |
PMID:19346885 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions increases metabolic processing |
ISO |
[CYP3A5 gene polymorphism results in increased activity of CYP3A5 protein] which results in increased metabolism of Vincristine CYP3A5 protein results in increased metabolism of Vincristine |
CTD |
PMID:21225912 |
|
NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases expression |
ISO |
Vincristine results in increased expression of CYP4F3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
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G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of CYP4V2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:50,111,803...50,136,741
Ensembl chr16:50,111,306...50,136,727
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G |
Cysltr1 |
cysteinyl leukotriene receptor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of CYSLTR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:77,671,028...77,700,491
Ensembl chr X:77,674,150...77,700,269
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G |
Daam1 |
dishevelled associated activator of morphogenesis 1 |
increases expression |
ISO |
Vincristine results in increased expression of DAAM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:94,606,675...94,739,026
Ensembl chr 6:94,636,222...94,739,026
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|
G |
Dcaf8 |
DDB1 and CUL4 associated factor 8 |
increases expression |
ISO |
Vincristine results in increased expression of DCAF8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:90,532,153...90,587,542
Ensembl chr13:90,532,326...90,591,796
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G |
Dcn |
decorin |
decreases response to substance |
ISO |
DCN mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
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G |
Dcun1d1 |
defective in cullin neddylation 1 domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of DCUN1D1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:122,476,173...122,527,153
Ensembl chr 2:122,476,173...122,646,445
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G |
Dcun1d4 |
defective in cullin neddylation 1 domain containing 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of DCUN1D4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:37,210,721...37,294,517
Ensembl chr14:37,210,721...37,294,472
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Vincristine results in increased expression of DDIT3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
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G |
Ddx50 |
DExD-box helicase 50 |
increases expression |
ISO |
Vincristine results in increased expression of DDX50 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:32,239,736...32,269,522
Ensembl chr20:32,239,748...32,269,145
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G |
Ddx52 |
DExD-box helicase 52 |
increases expression |
ISO |
Vincristine results in increased expression of DDX52 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:71,253,667...71,276,397
Ensembl chr10:71,253,598...71,277,277
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G |
Dennd5a |
DENN domain containing 5A |
increases expression |
ISO |
Vincristine results in increased expression of DENND5A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529
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G |
Dgcr8 |
DGCR8 microprocessor complex subunit |
decreases expression |
ISO |
Vincristine results in decreased expression of DGCR8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:86,852,682...86,885,233
Ensembl chr11:86,852,711...86,885,224
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G |
Dhfr |
dihydrofolate reductase |
decreases expression |
ISO |
Vincristine results in decreased expression of DHFR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
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G |
Dhrs11 |
dehydrogenase/reductase 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of DHRS11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
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G |
Dhrs2 |
dehydrogenase/reductase 2 |
increases expression |
ISO |
Vincristine results in increased expression of DHRS2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
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G |
Dhrs7 |
dehydrogenase/reductase 7 |
increases expression |
ISO |
Vincristine results in increased expression of DHRS7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
decreases expression |
ISO |
Vincristine results in decreased expression of DIABLO mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
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G |
Dido1 |
death inducer-obliterator 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of DIDO1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:176,162,886...176,216,868
Ensembl chr 3:176,162,886...176,197,753
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G |
Dip2a |
disco-interacting protein 2 homolog A |
increases expression |
ISO |
Vincristine results in increased expression of DIP2A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
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G |
Dmd |
dystrophin |
increases expression |
ISO |
Vincristine results in increased expression of DMD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:51,149,358...53,519,271
Ensembl chr X:51,286,737...53,519,259
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G |
Dna2 |
DNA replication helicase/nuclease 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of DNA2 mRNA |
CTD |
PMID:23649840 |
|
|
|
G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
decreases expression |
ISO |
Vincristine results in decreased expression of DNAJB1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
|
|
G |
Dnajc7 |
DnaJ heat shock protein family (Hsp40) member C7 |
increases expression |
ISO |
Vincristine results in increased expression of DNAJC7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:88,498,271...88,533,730
Ensembl chr10:88,498,238...88,533,829
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G |
Dnase1l3 |
deoxyribonuclease 1-like 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of DNASE1L3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:18,710,492...18,736,476
Ensembl chr15:18,710,492...18,736,473
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G |
Dnmbp |
dynamin binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of DNMBP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:263,625,503...263,718,784
Ensembl chr 1:263,625,501...263,718,745
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G |
Dock4 |
dedicator of cytokinesis 4 |
increases expression |
ISO |
Vincristine results in increased expression of DOCK4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:60,374,839...60,782,648
Ensembl chr 6:60,566,196...60,782,556
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G |
Dock8 |
dedicator of cytokinesis 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of DOCK8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:242,934,685...243,153,472
Ensembl chr 1:242,959,488...243,153,465
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G |
Dok4 |
docking protein 4 |
increases expression |
ISO |
Vincristine results in increased expression of DOK4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:10,563,423...10,574,094
Ensembl chr19:10,563,423...10,574,093
|
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G |
Donson |
DNA replication fork stabilization factor DONSON |
decreases expression |
ISO |
Vincristine results in decreased expression of DONSON mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:31,834,608...31,847,751
Ensembl chr11:31,837,839...31,847,490
|
|
G |
Dpp4 |
dipeptidylpeptidase 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of DPP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
|
|
G |
Dpyd |
dihydropyrimidine dehydrogenase |
increases response to substance |
ISO |
DPYD gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:20864405 |
|
NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
|
|
G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
increases expression |
ISO |
Vincristine results in increased expression of DRAM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:28,898,647...28,932,641
Ensembl chr 7:28,898,649...28,932,641
|
|
G |
Dtl |
denticleless E3 ubiquitin protein ligase homolog |
decreases expression |
ISO |
Vincristine results in decreased expression of DTL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
|
|
G |
Dusp10 |
dual specificity phosphatase 10 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP10 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
|
|
G |
Dusp16 |
dual specificity phosphatase 16 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP16 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
|
|
G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
|
|
G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
Vincristine results in increased expression of DUSP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
|
|
G |
Dynlt2 |
dynein light chain Tctex-type 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of DYNLT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:56,970,673...56,982,657
Ensembl chr 1:56,970,654...56,982,642
|
|
G |
E2f8 |
E2F transcription factor 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of E2F8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
|
|
G |
Ebf1 |
EBF transcription factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of EBF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:23,654,849...24,051,627
Ensembl chr10:23,661,013...24,050,209
|
|
G |
Ednrb |
endothelin receptor type B |
increases expression |
EXP |
Vincristine results in increased expression of EDNRB mRNA |
CTD |
PMID:20624997 |
|
NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
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|
G |
Efna4 |
ephrin A4 |
decreases expression |
ISO |
Vincristine results in decreased expression of EFNA4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:188,655,920...188,660,179
Ensembl chr 2:188,655,912...188,660,179
|
|
G |
Egfl6 |
EGF-like-domain, multiple 6 |
decreases response to substance |
ISO |
EGFL6 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr X:29,430,789...29,488,737
Ensembl chr X:29,430,831...29,488,739
|
|
G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
Vincristine results in increased expression of EGR1 mRNA |
CTD |
PMID:12706485 PMID:23649840 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
|
|
G |
Egr3 |
early growth response 3 |
increases expression |
ISO |
Vincristine results in increased expression of EGR3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
|
|
G |
Ehbp1l1 |
EH domain binding protein 1-like 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EHBP1L1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:221,061,878...221,084,423
Ensembl chr 1:221,062,147...221,084,129
|
|
G |
Eif1 |
eukaryotic translation initiation factor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
|
|
G |
Eif1ad |
eukaryotic translation initiation factor 1A domain containing |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF1AD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:220,746,387...220,751,687
Ensembl chr 1:220,746,387...220,751,684
|
|
G |
Eif3b |
eukaryotic translation initiation factor 3, subunit B |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF3B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
|
|
G |
Eif3m |
eukaryotic translation initiation factor 3, subunit M |
increases expression |
ISO |
Vincristine results in increased expression of EIF3M mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:94,990,086...95,007,690
Ensembl chr 3:94,990,068...95,007,712
|
|
G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
increases expression |
ISO |
Vincristine results in increased expression of EIF4A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:56,271,257...56,276,764
Ensembl chr10:56,271,257...56,276,764
|
|
G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
decreases expression |
ISO |
Vincristine results in decreased expression of EIF4A2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
|
|
G |
Elf3 |
E74 like ETS transcription factor 3 |
increases expression |
ISO |
Vincristine results in increased expression of ELF3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
|
|
G |
Elk3 |
ETS transcription factor ELK3 |
increases expression |
ISO |
Vincristine results in increased expression of ELK3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
|
|
G |
Eme2 |
essential meiotic structure-specific endonuclease subunit 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of EME2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:14,253,552...14,257,017
Ensembl chr10:14,254,252...14,256,930
|
|
G |
Eml6 |
EMAP like 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of EML6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:114,174,282...114,484,663
Ensembl chr14:114,176,051...114,484,127
|
|
G |
Enox1 |
ecto-NOX disulfide-thiol exchanger 1 |
increases expression |
ISO |
Vincristine results in increased expression of ENOX1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:59,331,134...59,884,512
Ensembl chr15:59,678,165...59,884,511
|
|
G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
increases expression |
ISO |
Vincristine results in increased expression of ENPP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
|
|
G |
Ensa |
endosulfine alpha |
decreases expression |
ISO |
Vincristine results in decreased expression of ENSA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:197,752,544...197,759,882
Ensembl chr 2:197,752,544...197,759,882
|
|
G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
increases expression |
ISO |
Vincristine results in increased expression of ENTPD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
|
|
G |
Eomes |
eomesodermin |
decreases expression |
ISO |
Vincristine results in decreased expression of EOMES mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
|
|
G |
Epg5 |
ectopic P-granules autophagy protein 5 homolog |
increases expression |
ISO |
Vincristine results in increased expression of EPG5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:74,299,965...74,397,115
Ensembl chr18:74,299,931...74,395,547
|
|
G |
Ephb1 |
Eph receptor B1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EPHB1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:110,376,954...110,813,193
Ensembl chr 8:110,376,954...110,813,000
|
|
G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EPHX1 mRNA |
CTD |
PMID:21382384 |
|
NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
|
|
G |
Epm2aip1 |
EPM2A interacting protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EPM2AIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:119,524,039...119,531,387
Ensembl chr 8:119,524,039...119,531,387
|
|
G |
Epor |
erythropoietin receptor |
decreases expression |
ISO |
Vincristine results in decreased expression of EPOR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
|
|
G |
Eprs |
glutamyl-prolyl-tRNA synthetase |
increases expression |
EXP |
Vincristine results in increased expression of EPRS mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
|
|
G |
Epsti1 |
epithelial stromal interaction 1 |
increases expression |
ISO |
Vincristine results in increased expression of EPSTI1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:60,084,966...60,190,360
Ensembl chr15:60,084,918...60,190,363
|
|
G |
Erich3 |
glutamate-rich 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of ERICH3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:260,947,970...261,049,973
Ensembl chr 2:260,997,497...261,032,821
|
|
G |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ESCO2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
|
|
G |
Esd |
esterase D |
decreases expression |
ISO |
Vincristine results in decreased expression of ESD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
|
|
G |
Esm1 |
endothelial cell-specific molecule 1 |
decreases expression |
EXP |
Vincristine results in decreased expression of ESM1 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
|
|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Vincristine binds to and results in decreased activity of ESR1 protein |
CTD |
PMID:25752796 |
|
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
|
|
G |
Evc |
EvC ciliary complex subunit 1 |
increases expression |
ISO |
Vincristine results in increased expression of EVC mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:78,213,601...78,253,266
Ensembl chr14:78,213,635...78,253,266
|
|
G |
Exo1 |
exonuclease 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of EXO1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
|
|
G |
Exog |
exo/endonuclease G |
decreases expression |
ISO |
Vincristine results in decreased expression of EXOG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:128,133,398...128,153,110
Ensembl chr 8:128,133,431...128,153,110
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|
G |
Ext1 |
exostosin glycosyltransferase 1 |
increases expression |
ISO |
Vincristine results in increased expression of EXT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
|
|
G |
F2 |
coagulation factor II |
affects expression |
ISO |
Vincristine affects the expression of F2 protein |
CTD |
PMID:12542493 |
|
NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
|
|
G |
F3 |
coagulation factor III, tissue factor |
increases expression |
ISO EXP |
Vincristine results in increased expression of F3 mRNA; Vincristine results in increased expression of F3 protein |
CTD |
PMID:12542493 PMID:20624997 |
|
NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
|
|
G |
Fam13b |
family with sequence similarity 13, member B |
increases expression |
ISO |
Vincristine results in increased expression of FAM13B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:27,223,345...27,304,462
Ensembl chr18:27,223,345...27,289,876
|
|
G |
Fam13c |
family with sequence similarity 13, member C |
increases expression |
ISO |
Vincristine results in increased expression of FAM13C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:19,358,869...19,470,212
Ensembl chr20:19,360,230...19,479,325
|
|
G |
Fam171b |
family with sequence similarity 171, member B |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM171B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
|
|
G |
Fam174a |
family with sequence similarity 174, member A |
increases expression |
ISO |
Vincristine results in increased expression of FAM174A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:102,862,761...102,881,046
Ensembl chr 9:102,862,890...102,881,038
|
|
G |
Fam71f1 |
family with sequence similarity 71, member F1 |
increases expression |
ISO |
Vincristine results in increased expression of FAM71F1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:56,591,719...56,615,157
Ensembl chr 4:56,591,715...56,615,158
|
|
G |
Fam76b |
family with sequence similarity 76, member B |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM76B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:12,355,767...12,378,040
Ensembl chr 8:12,355,767...12,374,689
|
|
G |
Fam81a |
family with sequence similarity 81, member A |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM81A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:76,521,662...76,579,387
Ensembl chr 8:76,521,657...76,579,387
|
|
G |
Fam83d |
family with sequence similarity 83, member D |
decreases expression |
ISO |
Vincristine results in decreased expression of FAM83D mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
|
|
G |
Fancf |
FA complementation group F |
decreases expression |
ISO |
Vincristine results in decreased expression of FANCF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:107,229,516...107,232,321
Ensembl chr 1:107,231,292...107,232,305
|
|
G |
Fancg |
FA complementation group G |
decreases expression |
ISO |
Vincristine results in decreased expression of FANCG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
|
|
G |
Fas |
Fas cell surface death receptor |
increases expression |
ISO |
Vincristine results in increased expression of FAS mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
|
|
G |
Faslg |
Fas ligand |
increases expression |
ISO |
Vincristine results in increased expression of FASLG protein |
CTD |
PMID:11716366 |
|
NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
|
|
G |
Fastkd2 |
FAST kinase domains 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FASTKD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:70,448,386...70,471,420
Ensembl chr 9:70,450,444...70,470,550
|
|
G |
Fbxl20 |
F-box and leucine-rich repeat protein 20 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXL20 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:86,036,745...86,099,699
Ensembl chr10:86,043,235...86,098,694
|
|
G |
Fbxl4 |
F-box and leucine-rich repeat protein 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXL4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:36,555,061...36,628,920
Ensembl chr 5:36,555,109...36,629,689
|
|
G |
Fbxo33 |
F-box protein 33 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXO33 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:80,302,291...80,334,536
Ensembl chr 6:80,302,303...80,334,522
|
|
G |
Fbxo5 |
F-box protein 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXO5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
|
|
G |
Fbxo9 |
f-box protein 9 |
decreases expression |
ISO |
Vincristine results in decreased expression of FBXO9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
|
|
G |
Fcgr2b |
Fc fragment of IgG receptor IIb |
increases expression |
EXP |
Vincristine results in increased expression of FCGR2B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
|
|
G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression |
ISO |
Vincristine results in increased expression of FDFT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
|
|
G |
Fermt2 |
FERM domain containing kindlin 2 |
increases expression |
ISO |
Vincristine results in increased expression of FERMT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
|
|
G |
Ffar2 |
free fatty acid receptor 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FFAR2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:89,268,197...89,271,942
Ensembl chr 1:89,268,938...89,269,930
|
|
G |
Fgr |
FGR proto-oncogene, Src family tyrosine kinase |
decreases expression |
ISO |
Vincristine results in decreased expression of FGR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
|
|
G |
Flot2 |
flotillin 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FLOT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:65,304,901...65,329,332
Ensembl chr10:65,304,902...65,329,312
|
|
G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of FLT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
|
|
G |
Fmnl3 |
formin-like 3 |
increases expression |
ISO |
Vincristine results in increased expression of FMNL3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:140,981,801...141,033,318
Ensembl chr 7:140,983,342...141,001,993
|
|
G |
Fnbp1 |
formin binding protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of FNBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:9,865,657...9,936,333
Ensembl chr 3:9,861,237...9,936,405
|
|
G |
Fnbp4 |
formin binding protein 4 |
increases expression |
ISO |
Vincristine results in increased expression of FNBP4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:79,570,610...79,610,122
Ensembl chr 3:79,570,625...79,610,454
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Vincristine results in increased expression of FOS protein |
CTD |
PMID:18930597 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
|
|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
Vincristine results in increased expression of FOSL2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
|
|
G |
Foxk2 |
forkhead box K2 |
decreases expression |
ISO |
Vincristine results in decreased expression of FOXK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:110,468,905...110,518,854
Ensembl chr10:110,469,290...110,518,848
|
|
G |
Foxp1 |
forkhead box P1 |
increases expression |
ISO |
Vincristine results in increased expression of FOXP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
|
|
G |
Fry |
FRY microtubule binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of FRY mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
|
|
G |
Fscn1 |
fascin actin-bundling protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of FSCN1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
|
|
G |
Fsd1l |
fibronectin type III and SPRY domain containing 1-like |
increases expression |
ISO |
Vincristine results in increased expression of FSD1L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:70,441,075...70,517,131
Ensembl chr 5:70,441,123...70,511,659
|
|
G |
Fubp1 |
far upstream element binding protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of FUBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
|
|
G |
Fut11 |
fucosyltransferase 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of FUT11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:4,031,504...4,035,064
Ensembl chr15:4,031,504...4,035,064
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G |
G3bp1 |
G3BP stress granule assembly factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of G3BP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
EXP ISO |
Vincristine results in increased expression of GADD45A mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
EXP |
Vincristine results in increased expression of GADD45B mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
EXP |
Vincristine results in increased expression of GADD45G mRNA |
CTD |
PMID:20624997 |
|
NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
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G |
Gart |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
decreases expression |
ISO |
Vincristine results in decreased expression of GART mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728
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G |
Gas7 |
growth arrest specific 7 |
decreases expression |
EXP |
Vincristine results in decreased expression of GAS7 mRNA |
CTD |
PMID:20624997 |
|
NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
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G |
Gbp1 |
guanylate binding protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of GBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
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G |
Gbp2 |
guanylate binding protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of GBP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
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G |
Gbp6 |
guanylate binding protein family member 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of GBP6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:5,927,568...5,954,923
Ensembl chr14:5,928,737...5,945,321
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
[GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine |
CTD |
PMID:10900222 |
|
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions decreases expression |
ISO |
[GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine Vincristine results in decreased expression of GCLM mRNA |
CTD |
PMID:10900222 PMID:23649840 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Vincristine results in increased expression of GDF15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
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G |
Gfi1 |
growth factor independent 1 transcriptional repressor |
decreases expression |
ISO |
Vincristine results in decreased expression of GFI1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
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G |
Gfm1 |
G elongation factor, mitochondrial 1 |
increases expression |
ISO |
Vincristine results in increased expression of GFM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:164,601,575...164,646,478
Ensembl chr 2:164,601,586...164,646,439
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G |
Gjc1 |
gap junction protein, gamma 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of GJC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:90,781,408...90,912,440
Ensembl chr10:90,781,402...90,912,287
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G |
Gli1 |
GLI family zinc finger 1 |
increases response to substance |
ISO |
GLI1 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:20864405 |
|
NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
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G |
Glipr1 |
GLI pathogenesis-related 1 |
increases expression |
ISO |
Vincristine results in increased expression of GLIPR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:54,767,828...54,778,823
Ensembl chr 7:54,767,827...54,778,848
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G |
Gmfb |
glia maturation factor, beta |
increases expression |
ISO |
Vincristine results in increased expression of GMFB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:23,597,846...23,611,541
Ensembl chr15:23,601,368...23,606,634
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G |
Gmppb |
GDP-mannose pyrophosphorylase B |
decreases expression |
ISO |
Vincristine results in decreased expression of GMPPB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:116,826,251...116,856,159
Ensembl chr 8:116,826,680...116,856,159
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G |
Gna15 |
G protein subunit alpha 15 |
increases expression |
ISO |
Vincristine results in increased expression of GNA15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:11,054,249...11,075,152
Ensembl chr 7:11,054,333...11,077,251
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G |
Gng2 |
G protein subunit gamma 2 |
increases expression |
ISO |
Vincristine results in increased expression of GNG2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:4,748,242...4,853,555
Ensembl chr15:4,850,122...4,853,555
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G |
Gon4l |
gon-4 like |
increases expression |
ISO |
Vincristine results in increased expression of GON4L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:188,139,730...188,212,902
Ensembl chr 2:188,139,730...188,215,723
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G |
Gopc |
golgi associated PDZ and coiled-coil motif containing |
decreases expression |
ISO |
Vincristine results in decreased expression of GOPC mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:33,471,355...33,521,281
Ensembl chr20:33,471,351...33,521,311
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G |
Gpatch11 |
G patch domain containing 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPATCH11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:1,410,461...1,421,506
Ensembl chr 6:1,410,507...1,423,041
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G |
Gpatch2 |
G patch domain containing 2 |
increases expression |
ISO |
Vincristine results in increased expression of GPATCH2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:105,684,300...105,824,405
Ensembl chr13:105,684,420...105,815,606
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G |
Gpatch2l |
G patch domain containing 2-like |
increases expression |
ISO |
Vincristine results in increased expression of GPATCH2L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:110,093,767...110,228,943
Ensembl chr 6:110,093,819...110,227,475
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G |
Gpbp1l1 |
GC-rich promoter binding protein 1-like 1 |
increases expression |
ISO |
Vincristine results in increased expression of GPBP1L1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:135,398,926...135,439,772
Ensembl chr 5:135,412,256...135,439,577
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G |
Gpc3 |
glypican 3 |
increases response to substance |
ISO |
GPC3 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr X:139,579,268...139,947,093
Ensembl chr X:139,579,268...139,916,883
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPD2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
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G |
Gpnmb |
glycoprotein nmb |
increases expression |
ISO |
Vincristine results in increased expression of GPNMB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
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G |
Gpr132 |
G protein-coupled receptor 132 |
increases expression |
ISO |
Vincristine results in increased expression of GPR132 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:137,652,213...137,671,658
Ensembl chr 6:137,652,213...137,664,133
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G |
Gpr137b |
G protein-coupled receptor 137B |
increases expression |
ISO |
Vincristine results in increased expression of GPR137B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
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G |
Gpr180 |
G protein-coupled receptor 180 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPR180 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:103,340,387...103,369,633
Ensembl chr15:103,344,476...103,369,630
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G |
Gpr55 |
G protein-coupled receptor 55 |
increases expression |
ISO |
Vincristine results in increased expression of GPR55 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:92,961,431...93,011,157
Ensembl chr 9:92,962,738...92,963,697
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G |
Gpr63 |
G protein-coupled receptor 63 |
decreases expression |
ISO |
Vincristine results in decreased expression of GPR63 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:39,258,438...39,374,187
Ensembl chr 5:39,329,423...39,370,900
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G |
Gpr84 |
G protein-coupled receptor 84 |
increases expression |
ISO |
Vincristine results in increased expression of GPR84 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:144,934,606...144,937,194
Ensembl chr 7:144,934,610...144,936,803
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G |
Gramd2b |
GRAM domain containing 2B |
increases expression |
ISO |
Vincristine results in increased expression of GRAMD2B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:51,492,196...51,591,028
Ensembl chr18:51,492,196...51,591,026
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G |
Grap2 |
GRB2-related adaptor protein 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of GRAP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:121,791,330...121,864,835
Ensembl chr 7:121,841,855...121,864,679
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G |
Gspt1 |
G1 to S phase transition 1 |
increases expression |
ISO |
Vincristine results in increased expression of GSPT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:4,313,100...4,347,661
Ensembl chr10:4,312,863...4,446,200
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G |
Gstm1 |
glutathione S-transferase mu 1 |
affects response to substance decreases response to substance multiple interactions |
ISO |
GSTM1 gene polymorphism affects the susceptibility to Vincristine GSTM1 protein results in decreased susceptibility to Vincristine Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:15044619 PMID:15713801 |
|
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
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G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases response to substance multiple interactions |
ISO |
GSTP1 protein results in decreased susceptibility to Vincristine GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine] |
CTD |
PMID:10900222 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
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G |
Gtf3c3 |
general transcription factor IIIC subunit 3 |
increases expression |
ISO |
Vincristine results in increased expression of GTF3C3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:60,999,159...61,033,612
Ensembl chr 9:60,969,061...61,033,580
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G |
Gtpbp3 |
GTP binding protein 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of GTPBP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:19,897,135...19,902,226
Ensembl chr16:19,896,986...19,902,245
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G |
H2ax |
H2A.X variant histone |
multiple interactions |
ISO |
[CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein |
CTD |
PMID:28669723 |
|
NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
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G |
H2bc12 |
H2B clustered histone 12 |
increases expression |
ISO |
Vincristine results in increased expression of H2BC12 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801
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G |
H4c3 |
H4 clustered histone 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of H4C3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
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G |
Hamp |
hepcidin antimicrobial peptide |
decreases expression |
ISO |
Vincristine results in decreased expression of HAMP mRNA |
CTD |
PMID:25633564 |
|
NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
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G |
Hbb |
hemoglobin subunit beta |
decreases expression |
ISO |
Vincristine results in decreased expression of HBB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
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G |
Hbb-b1 |
hemoglobin, beta adult major chain |
decreases expression |
ISO |
Vincristine results in decreased expression of HBD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:168,945,531...168,953,023
Ensembl chr 1:168,945,449...168,965,566
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G |
Hdac1 |
histone deacetylase 1 |
decreases expression |
EXP |
Vincristine results in decreased expression of HDAC1 protein |
CTD |
PMID:27474498 |
|
NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
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G |
Hdac4 |
histone deacetylase 4 |
decreases expression |
EXP |
Vincristine results in decreased expression of HDAC4 protein |
CTD |
PMID:27474498 |
|
NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
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G |
Hdac9 |
histone deacetylase 9 |
decreases expression |
ISO |
Vincristine results in decreased expression of HDAC9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
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G |
Hdhd3 |
haloacid dehalogenase-like hydrolase domain containing 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of HDHD3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:78,358,183...78,361,650
Ensembl chr 5:78,358,203...78,361,647
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G |
Hectd4 |
HECT domain E3 ubiquitin protein ligase 4 |
increases expression |
ISO |
Vincristine results in increased expression of HECTD4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:40,712,078...40,860,930
Ensembl chr12:40,713,841...40,822,159
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G |
Hells |
helicase, lymphoid specific |
decreases expression |
ISO |
Vincristine results in decreased expression of HELLS mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183 Ensembl chr 1:257,766,691...257,949,183
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G |
Heph |
hephaestin |
increases expression |
ISO |
Vincristine results in increased expression of HEPH mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:65,377,313...65,658,479
Ensembl chr X:65,563,122...65,658,516
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G |
Hhat |
hedgehog acyltransferase |
increases expression |
ISO |
Vincristine results in increased expression of HHAT mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:111,235,325...111,489,075
Ensembl chr13:111,236,466...111,474,411
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G |
Hic1 |
HIC ZBTB transcriptional repressor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HIC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:62,007,150...62,010,774
Ensembl chr10:62,007,150...62,009,582
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
decreases expression |
ISO |
Vincristine results in decreased expression of HILPDA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
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G |
Hint1 |
histidine triad nucleotide binding protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HINT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
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G |
Hint3 |
histidine triad nucleotide binding protein 3 |
increases expression |
ISO |
Vincristine results in increased expression of HINT3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:29,413,425...29,423,288
Ensembl chr 1:29,413,365...29,423,347
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G |
Hist1h2bd |
histone cluster 1 H2B family member D |
increases expression |
ISO |
Vincristine results in increased expression of H2BC5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
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G |
Hist1h2bq |
histone cluster 1 H2B family member Q |
increases expression |
ISO |
Vincristine results in increased expression of H2BC7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
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G |
Hivep3 |
HIVEP zinc finger 3 |
increases expression |
ISO |
Vincristine results in increased expression of HIVEP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:138,774,501...139,077,403
Ensembl chr 5:139,007,642...139,077,377
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G |
Hlf |
HLF transcription factor, PAR bZIP family member |
increases expression |
ISO |
Vincristine results in increased expression of HLF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:77,836,352...77,918,656
Ensembl chr10:77,840,568...77,918,191
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G |
Hmcn1 |
hemicentin 1 |
increases response to substance |
ISO |
HMCN1 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
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G |
Hmga2 |
high mobility group AT-hook 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of HMGA2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
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G |
Hmgb1 |
high mobility group box 1 |
decreases expression increases secretion decreases response to substance |
EXP ISO |
Vincristine results in decreased expression of HMGB1 protein Vincristine results in increased secretion of HMGB1 protein HMGB1 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:27474498 PMID:27807322 |
|
NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
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G |
Hmgn5 |
high mobility group nucleosome binding domain 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of HMGN5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:80,134,557...80,142,902
Ensembl chr X:80,134,557...80,142,902
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G |
Hmox1 |
heme oxygenase 1 |
decreases expression increases expression |
ISO EXP |
Vincristine results in decreased expression of HMOX1 mRNA Vincristine results in increased expression of HMOX1 mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPA2B1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
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G |
Hnrnpd |
heterogeneous nuclear ribonucleoprotein D |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPD mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578
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G |
Hnrnpdl |
heterogeneous nuclear ribonucleoprotein D-like |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPDL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:11,199,114...11,204,670
Ensembl chr14:11,198,896...11,202,669
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G |
Hnrnpr |
heterogeneous nuclear ribonucleoprotein R |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:154,668,194...154,699,967
Ensembl chr 5:154,668,179...154,699,966
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G |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
decreases expression |
ISO |
Vincristine results in decreased expression of HNRNPU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
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G |
Hook1 |
hook microtubule-tethering protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HOOK1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
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G |
Hook3 |
hook microtubule-tethering protein 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of HOOK3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:70,710,347...70,818,789
|
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G |
Hoxb7 |
homeo box B7 |
decreases expression |
ISO |
Vincristine results in decreased expression of HOXB7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:84,135,224...84,138,642
Ensembl chr10:84,135,116...84,138,637
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G |
Hpdl |
4-hydroxyphenylpyruvate dioxygenase-like |
decreases expression |
ISO |
Vincristine results in decreased expression of HPDL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:135,675,826...135,677,432
Ensembl chr 5:135,675,832...135,677,432
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G |
Hras |
HRas proto-oncogene, GTPase |
increases expression |
ISO |
Vincristine results in increased expression of HRAS mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
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G |
Hs2st1 |
heparan sulfate 2-O-sulfotransferase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HS2ST1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517
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G |
Hspb11 |
heat shock protein family B (small), member 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of HSPB11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:126,856,128...126,882,913
Ensembl chr 5:126,856,705...126,882,909
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G |
Hspb2 |
heat shock protein family B (small) member 2 |
decreases response to substance |
ISO |
HSPB2 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:17524270 |
|
NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of HSPD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
multiple interactions increases expression |
EXP |
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Vincristine Vincristine results in increased expression of HTR2A protein |
CTD |
PMID:18930597 |
|
NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
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G |
Hyls1 |
HYLS1, centriolar and ciliogenesis associated |
decreases expression |
ISO |
Vincristine results in decreased expression of HYLS1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO EXP |
Vincristine results in increased expression of ICAM1 mRNA |
CTD |
PMID:20624997 PMID:23649840 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Icam4 |
intercellular adhesion molecule 4, Landsteiner-Wiener blood group |
increases expression |
ISO |
Vincristine results in increased expression of ICAM4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:22,047,697...22,048,793
Ensembl chr 8:22,047,697...22,048,793
|
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Vincristine results in increased expression of ID2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
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G |
Id3 |
inhibitor of DNA binding 3, HLH protein |
increases response to substance |
ISO |
ID3 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
|
NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
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G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
Vincristine results in increased expression of IER3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
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G |
Ifi44 |
interferon-induced protein 44 |
increases expression |
ISO |
Vincristine results in increased expression of IFI44 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
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G |
Ifi44l |
interferon-induced protein 44-like |
increases expression |
ISO |
Vincristine results in increased expression of IFI44L mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
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G |
Ifih1 |
interferon induced with helicase C domain 1 |
increases expression |
ISO |
Vincristine results in increased expression of IFIH1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
|
|
G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
increases expression |
ISO |
Vincristine results in increased expression of IFIT2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
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|
G |
Ifng |
interferon gamma |
increases expression |
ISO |
Vincristine results in increased expression of IFNG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Ifrd1 |
interferon-related developmental regulator 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of IFRD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
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G |
Ift20 |
intraflagellar transport 20 |
increases expression |
ISO |
Vincristine results in increased expression of IFT20 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:65,805,808...65,811,353
Ensembl chr10:65,805,860...65,811,351
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G |
Ift43 |
intraflagellar transport 43 |
increases expression |
ISO |
Vincristine results in increased expression of IFT43 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:109,939,323...110,016,646
Ensembl chr 6:109,939,345...110,016,644
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|
G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases response to substance |
ISO |
Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]] IGF1 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:9452187 PMID:16740780 |
|
NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
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G |
Ighg1 |
immunoglobulin heavy constant gamma 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of IGHG1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218
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G |
Igkc |
immunoglobulin kappa constant |
decreases expression |
ISO |
Vincristine results in decreased expression of IGKC mRNA |
CTD |
PMID:23649840 |
|
|
|
G |
Ikzf2 |
IKAROS family zinc finger 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of IKZF2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:76,621,230...76,771,017
Ensembl chr 9:76,621,230...76,768,806
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Vincristine results in increased expression of IL10RA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
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G |
Il15 |
interleukin 15 |
increases expression |
ISO |
Vincristine results in increased expression of IL15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
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G |
Il17rb |
interleukin 17 receptor B |
decreases expression |
ISO |
Vincristine results in decreased expression of IL17RB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:6,064,287...6,077,978
Ensembl chr16:6,064,288...6,077,978
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G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
EXP |
Vincristine results in increased expression of IL1B mRNA Sumatriptan inhibits the reaction [Vincristine results in increased expression of IL1B mRNA] |
CTD |
PMID:20624997 PMID:29958920 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il1r1 |
interleukin 1 receptor type 1 |
increases expression |
ISO |
Vincristine results in increased expression of IL1R1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
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G |
Il2 |
interleukin 2 |
multiple interactions increases expression |
EXP |
tropisetron inhibits the reaction [Vincristine results in increased expression of IL2 protein] |
CTD |
PMID:24374478 |
|
NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
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G |
Il23a |
interleukin 23 subunit alpha |
increases expression |
ISO |
Vincristine results in increased expression of IL23A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
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G |
Il36g |
interleukin 36, gamma |
increases expression |
ISO |
Vincristine results in increased expression of IL36G mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:1,285,658...1,291,836
Ensembl chr 3:1,285,664...1,291,865
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G |
Il6 |
interleukin 6 |
affects response to substance increases expression |
EXP ISO |
IL6 protein affects the susceptibility to Vincristine Vincristine results in increased expression of IL6 protein Vincristine results in increased expression of IL6 mRNA |
CTD |
PMID:16001973 PMID:18270703 PMID:18652822 PMID:23649840 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Il7 |
interleukin 7 |
increases expression |
ISO |
Vincristine results in increased expression of IL7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
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G |
Ildr1 |
immunoglobulin-like domain containing receptor 1 |
increases expression |
ISO |
Vincristine results in increased expression of ILDR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:67,004,042...67,037,115
Ensembl chr11:67,004,042...67,037,115
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G |
Ildr2 |
immunoglobulin-like domain containing receptor 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ILDR2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:84,474,191...84,532,347
Ensembl chr13:84,474,319...84,530,031
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G |
Impa2 |
inositol monophosphatase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of IMPA2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:63,016,577...63,050,123
Ensembl chr18:63,016,577...63,047,781
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G |
Ina |
internexin neuronal intermediate filament protein, alpha |
multiple interactions |
ISO |
INA affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine] |
CTD |
PMID:21246521 |
|
NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
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G |
Ing2 |
inhibitor of growth family, member 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ING2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:47,714,756...47,725,836
Ensembl chr16:47,717,951...47,725,836
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G |
Inha |
inhibin subunit alpha |
decreases expression |
EXP |
Vincristine results in decreased expression of INHA mRNA |
CTD |
PMID:20624997 |
|
NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
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G |
Inhbe |
inhibin subunit beta E |
increases expression |
ISO |
Vincristine results in increased expression of INHBE mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
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G |
Inpp1 |
inositol polyphosphate-1-phosphatase |
increases expression |
ISO |
Vincristine results in increased expression of INPP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:53,544,602...53,574,303
Ensembl chr 9:53,546,018...53,574,690
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G |
Inpp4b |
inositol polyphosphate-4-phosphatase type II B |
increases expression |
ISO |
Vincristine results in increased expression of INPP4B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
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G |
Ints11 |
integrator complex subunit 11 |
decreases expression |
ISO |
Vincristine results in decreased expression of INTS11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:173,318,435...173,336,930
Ensembl chr 5:173,318,479...173,336,930
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G |
Ints5 |
integrator complex subunit 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of INTS5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:225,091,612...225,096,390
Ensembl chr 1:225,091,612...225,096,390
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G |
Ipo5 |
importin 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of IPO5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:106,243,110...106,293,326
Ensembl chr15:106,257,650...106,292,112
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G |
Iqgap2 |
IQ motif containing GTPase activating protein 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of IQGAP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:26,161,628...26,439,067
Ensembl chr 2:26,167,199...26,438,790
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G |
Irak2 |
interleukin-1 receptor-associated kinase 2 |
increases expression |
ISO |
Vincristine results in increased expression of IRAK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053
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G |
Ireb2 |
iron responsive element binding protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of IREB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
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G |
Irf1 |
interferon regulatory factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of IRF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
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G |
Isg20 |
interferon stimulated exonuclease gene 20 |
increases expression |
ISO |
Vincristine results in increased expression of ISG20 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
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G |
Islr |
immunoglobulin superfamily containing leucine-rich repeat |
increases expression |
ISO |
Vincristine results in increased expression of ISLR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:62,946,732...62,949,675
Ensembl chr 8:62,946,732...62,948,720
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G |
Itga1 |
integrin subunit alpha 1 |
increases response to substance |
ISO |
ITGA1 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421
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G |
Itga4 |
integrin subunit alpha 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of ITGA4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
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G |
Itgam |
integrin subunit alpha M |
increases expression |
ISO |
Vincristine results in increased expression of ITGAM mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
|
|
G |
Itgb1bp2 |
integrin subunit beta 1 binding protein 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ITGB1BP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:71,342,770...71,347,623
Ensembl chr X:71,342,775...71,347,619
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|
G |
Itgb7 |
integrin subunit beta 7 |
decreases expression |
ISO |
Vincristine results in decreased expression of ITGB7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:143,820,236...143,837,802
Ensembl chr 7:143,820,900...143,837,780
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|
G |
Itgb8 |
integrin subunit beta 8 |
increases expression |
ISO |
Vincristine results in increased expression of ITGB8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:147,089,280...147,172,846
Ensembl chr 6:147,094,097...147,172,813
|
|
G |
Itpkb |
inositol-trisphosphate 3-kinase B |
decreases expression |
ISO |
Vincristine results in decreased expression of ITPKB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:98,615,287...98,710,426
Ensembl chr13:98,615,287...98,708,149
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|
G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
increases expression |
ISO |
Vincristine results in increased expression of ITPR1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
|
|
G |
Itprid2 |
ITPR interacting domain containing 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of ITPRID2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:66,593,767...66,631,143
Ensembl chr 3:66,593,934...66,631,723
|
|
G |
Itpripl1 |
ITPRIP like 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ITPRIPL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:119,616,473...119,619,865
Ensembl chr 3:119,616,945...119,619,865
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|
G |
Ivl |
involucrin |
increases expression |
ISO |
Vincristine results in increased expression of IVL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
|
|
G |
Ivns1abp |
influenza virus NS1A binding protein |
decreases expression |
ISO |
Vincristine results in decreased expression of IVNS1ABP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:68,702,970...68,722,472
Ensembl chr13:68,702,820...68,722,472
|
|
G |
Jade2 |
jade family PHD finger 2 |
increases expression |
ISO |
Vincristine results in increased expression of JADE2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:37,269,132...37,315,638
Ensembl chr10:37,270,183...37,311,625
|
|
G |
Jchain |
joining chain of multimeric IgA and IgM |
decreases expression |
ISO |
Vincristine results in decreased expression of JCHAIN mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
|
|
G |
Jmjd1c |
jumonji domain containing 1C |
increases expression |
ISO |
Vincristine results in increased expression of JMJD1C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:22,751,743...22,914,080
Ensembl chr20:22,751,743...22,882,672
|
|
G |
Jpt1 |
Jupiter microtubule associated homolog 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of JPT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:104,057,739...104,075,776
Ensembl chr10:104,057,697...104,075,777
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Vincristine results in increased expression of JUN mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Kat2b |
lysine acetyltransferase 2B |
increases expression |
ISO |
Vincristine results in increased expression of KAT2B mRNA |
CTD |
PMID:16001973 |
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NCBI chr 9:4,440,982...4,492,949
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G |
Kcmf1 |
potassium channel modulatory factor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of KCMF1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:100,759,526...100,783,017
Ensembl chr 4:100,759,526...100,783,750
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G |
Kcna5 |
potassium voltage-gated channel subfamily A member 5 |
increases response to substance |
ISO |
KCNA5 protein results in increased susceptibility to Vincristine |
CTD |
PMID:17428690 |
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NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
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G |
Kcnmb1 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
increases expression |
ISO |
Vincristine results in increased expression of KCNMB1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
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G |
Kcnn2 |
potassium calcium-activated channel subfamily N member 2 |
increases expression |
ISO |
Vincristine results in increased expression of KCNN2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
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G |
Kdm2b |
lysine demethylase 2B |
increases expression |
ISO |
Vincristine results in increased expression of KDM2B mRNA |
CTD |
PMID:23649840 |
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NCBI chr12:39,021,924...39,161,954
Ensembl chr12:39,078,119...39,161,956
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G |
Kdsr |
3-ketodihydrosphingosine reductase |
decreases expression |
ISO |
Vincristine results in decreased expression of KDSR mRNA |
CTD |
PMID:23649840 |
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NCBI chr13:26,779,386...26,812,271
Ensembl chr13:26,780,633...26,812,215
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G |
Klf12 |
Kruppel-like factor 12 |
decreases expression |
ISO |
Vincristine results in decreased expression of KLF12 mRNA |
CTD |
PMID:23649840 |
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NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
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G |
Klf6 |
Kruppel-like factor 6 |
increases expression |
ISO |
Vincristine results in increased expression of KLF6 mRNA |
CTD |
PMID:23649840 |
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NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
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G |
Klhl14 |
kelch-like family member 14 |
decreases expression |
ISO |
Vincristine results in decreased expression of KLHL14 mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:12,526,627...12,640,381
Ensembl chr18:12,528,111...12,640,716
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G |
Klhl28 |
kelch-like family member 28 |
increases expression |
ISO |
Vincristine results in increased expression of KLHL28 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 6:86,680,826...86,713,370
Ensembl chr 6:86,684,413...86,713,370
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G |
Kmt5b |
lysine methyltransferase 5B |
increases expression |
ISO |
Vincristine results in increased expression of KMT5B mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:219,000,844...219,050,211
Ensembl chr 1:219,000,844...219,050,211
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G |
Kpna2 |
karyopherin subunit alpha 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of KPNA2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
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G |
Krt23 |
keratin 23 |
increases response to substance |
ISO |
KRT23 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
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G |
Krt7 |
keratin 7 |
increases expression |
ISO |
Vincristine results in increased expression of KRT7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
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G |
Kynu |
kynureninase |
increases expression |
ISO |
Vincristine results in increased expression of KYNU mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
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G |
Lactb2 |
lactamase, beta 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of LACTB2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:4,982,348...5,005,111
Ensembl chr 5:4,982,348...5,005,109
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G |
Lama2 |
laminin subunit alpha 2 |
increases response to substance |
ISO |
LAMA2 mRNA results in increased susceptibility to Vincristine |
CTD |
PMID:25199881 |
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NCBI chr 1:18,491,264...19,143,486
Ensembl chr 1:18,491,384...19,143,269
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G |
Lamp3 |
lysosomal-associated membrane protein 3 |
increases expression |
ISO |
Vincristine results in increased expression of LAMP3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:84,930,965...85,000,694
Ensembl chr11:84,972,132...85,000,681
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G |
Larp1b |
La ribonucleoprotein 1B |
decreases expression |
ISO |
Vincristine results in decreased expression of LARP1B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:127,845,034...127,876,793
Ensembl chr 2:127,845,034...127,876,793
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G |
Lbh |
LBH regulator of WNT signaling pathway |
decreases expression |
ISO |
Vincristine results in decreased expression of LBH mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
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G |
Lcor |
ligand dependent nuclear receptor corepressor |
increases expression |
ISO |
Vincristine results in increased expression of LCOR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:260,775,091...260,839,549 NCBI chr 1:260,789,955...260,809,051
Ensembl chr 1:260,732,485...260,830,854
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G |
Lcorl |
ligand dependent nuclear receptor corepressor-like |
decreases expression |
ISO |
Vincristine results in decreased expression of LCORL mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:69,765,356...69,898,749
Ensembl chr14:69,800,156...69,897,384
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G |
Lcp2 |
lymphocyte cytosolic protein 2 |
increases expression |
ISO |
Vincristine results in increased expression of LCP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:18,996,523...19,043,289
Ensembl chr10:18,996,523...19,043,286
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G |
Ldlrad4 |
low density lipoprotein receptor class A domain containing 4 |
increases expression |
ISO |
Vincristine results in increased expression of LDLRAD4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
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G |
Ldlrap1 |
low density lipoprotein receptor adaptor protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of LDLRAP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
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G |
Leng8 |
leukocyte receptor cluster member 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of LENG8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:73,722,088...73,734,459
Ensembl chr 1:73,722,088...73,733,788
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G |
Lif |
LIF, interleukin 6 family cytokine |
increases expression |
ISO |
Vincristine results in increased expression of LIF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
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G |
Lima1 |
LIM domain and actin binding 1 |
increases expression |
ISO |
Vincristine results in increased expression of LIMA1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:141,428,113...141,528,447
Ensembl chr 7:141,428,063...141,528,397
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G |
Lims1 |
LIM zinc finger domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of LIMS1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:27,895,981...28,004,767
Ensembl chr20:27,954,433...28,002,082
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G |
Lmna |
lamin A/C |
increases expression |
ISO |
Vincristine results in increased expression of LMNA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
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G |
Lnpep |
leucyl and cystinyl aminopeptidase |
increases expression |
ISO |
Vincristine results in increased expression of LNPEP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:59,289,392...59,384,540
Ensembl chr 1:59,297,294...59,347,472 Ensembl chr 1:59,297,294...59,347,472
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G |
LOC100125367 |
hypothetical protein LOC100125367 |
decreases expression |
ISO |
Vincristine results in decreased expression of C1ORF74 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:111,890,825...111,893,308
Ensembl chr13:111,890,894...111,893,306
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G |
LOC100910882 |
RNA-binding protein 39-like |
decreases expression |
ISO |
Vincristine results in decreased expression of RBM23 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:152,226,011...152,259,236
Ensembl chr 3:151,691,514...151,724,654 Ensembl chr 3:151,691,514...151,724,654
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G |
LOC102549061 |
histone H2B type 1-N-like |
increases expression |
ISO |
Vincristine results in increased expression of H2BC3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:43,627,872...43,628,518
Ensembl chr17:43,627,930...43,628,310
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G |
LOC103690190 |
histone H2A type 1-E |
increases expression |
ISO |
Vincristine results in increased expression of H2AC6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188 Ensembl chr17:44,747,796...44,748,188
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G |
LOC690813 |
Ig kappa chain V-IV region-like |
decreases expression |
ISO |
Vincristine results in decreased expression of IGKV4-1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:17,107,590...17,110,056
Ensembl chr 3:17,107,861...17,108,471
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G |
LOC691918 |
similar to Centrosomal protein of 27 kDa (Cep27 protein) |
decreases expression |
ISO |
Vincristine results in decreased expression of HAUS2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:112,371,709...112,377,939
Ensembl chr 3:112,385,601...112,396,032 Ensembl chr 3:112,385,601...112,396,032
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G |
Lrba |
LPS responsive beige-like anchor protein |
decreases expression |
ISO |
Vincristine results in decreased expression of LRBA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:185,590,983...186,110,491
Ensembl chr 2:185,524,774...186,110,495
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G |
Lrch3 |
leucine rich repeats and calponin homology domain containing 3 |
increases expression |
ISO |
Vincristine results in increased expression of LRCH3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:71,008,950...71,108,229
Ensembl chr11:71,012,061...71,108,184
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G |
Lrp8 |
LDL receptor related protein 8 |
decreases expression |
ISO |
Vincristine results in decreased expression of LRP8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
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G |
Lrrc8c |
leucine rich repeat containing 8 VRAC subunit C |
decreases expression |
ISO |
Vincristine results in decreased expression of LRRC8C mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:5,283,655...5,378,738
Ensembl chr14:5,283,647...5,378,726
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G |
Lrrcc1 |
leucine rich repeat and coiled-coil centrosomal protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of LRRCC1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:88,384,796...88,414,012
Ensembl chr 2:88,384,796...88,414,012
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G |
Lrrfip1 |
LRR binding FLII interacting protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of LRRFIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:98,139,484...98,268,148
Ensembl chr 9:98,190,829...98,257,735
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G |
Lta |
lymphotoxin alpha |
increases expression |
ISO |
Vincristine results in increased expression of LTA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
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G |
Lto1 |
LTO1 maturation factor of ABCE1 |
decreases expression |
ISO |
Vincristine results in decreased expression of LTO1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:218,075,995...218,082,700
Ensembl chr 1:218,076,116...218,080,824
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G |
Lum |
lumican |
decreases response to substance |
ISO |
LUM mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
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G |
Ly96 |
lymphocyte antigen 96 |
increases expression |
ISO |
Vincristine results in increased expression of LY96 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:1,972,212...1,989,448
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G |
Lztfl1 |
leucine zipper transcription factor-like 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of LZTFL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:132,774,393...132,790,922
Ensembl chr 8:132,775,587...132,790,839
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G |
Lzts2 |
leucine zipper tumor suppressor 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of LZTS2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:264,765,256...264,776,553
Ensembl chr 1:264,768,105...264,776,616
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G |
Macf1 |
microtubule-actin crosslinking factor 1 |
increases expression |
ISO |
Vincristine results in increased expression of MACF1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:141,039,455...141,363,524
Ensembl chr 5:141,039,468...141,363,524
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G |
Macir |
macrophage immunometabolism regulator |
decreases expression |
ISO |
Vincristine results in decreased expression of MACIR mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:111,327,333...111,347,428
Ensembl chr 9:111,327,402...111,347,430
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G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Vincristine results in increased expression of MAFF mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
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G |
Magt1 |
magnesium transporter 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of MAGT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:77,023,423...77,061,603
Ensembl chr X:77,020,402...77,061,667
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G |
Man2a1 |
mannosidase, alpha, class 2A, member 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of MAN2A1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:112,293,388...112,451,677
Ensembl chr 9:112,293,388...112,451,677
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G |
Manea |
mannosidase, endo-alpha |
decreases expression |
ISO |
Vincristine results in decreased expression of MANEA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:40,845,103...40,867,025
Ensembl chr 5:40,844,998...40,867,023
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression |
ISO |
Vincristine results in increased expression of MAP1LC3B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
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G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of MAP3K1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
decreases expression |
ISO |
Vincristine results in decreased expression of MAP3K7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
increases expression |
ISO |
Vincristine results in increased expression of MAP3K8 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
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G |
Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
increases expression |
ISO |
Vincristine results in increased expression of MAP4K4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545
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G |
Mapkbp1 |
mitogen activated protein kinase binding protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of MAPKBP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:111,767,126...111,817,103
Ensembl chr 3:111,767,161...111,818,089
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G |
Mapre1 |
microtubule-associated protein, RP/EB family, member 1 |
decreases localization multiple interactions |
ISO |
Vincristine results in decreased localization of MAPRE1 protein olesoxime inhibits the reaction [Vincristine results in decreased localization of MAPRE1 protein] |
CTD |
PMID:20417191 |
|
NCBI chr 3:149,221,346...149,249,469
Ensembl chr 3:149,221,377...149,249,273
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G |
Mapre3 |
microtubule-associated protein, RP/EB family, member 3 |
multiple interactions affects localization |
ISO |
olesoxime inhibits the reaction [Vincristine results in decreased localization of MAPRE3 protein] Vincristine affects the localization of MAPRE3 protein |
CTD |
PMID:20417191 |
|
NCBI chr 6:26,878,738...26,923,459
Ensembl chr 6:26,878,744...26,889,882
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G |
Marchf7 |
membrane associated ring-CH-type finger 7 |
increases expression |
ISO |
Vincristine results in increased expression of MARCHF7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:46,284,961...46,325,230
Ensembl chr 3:46,286,712...46,324,057
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
increases expression |
ISO |
Vincristine results in increased expression of MARCKS mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
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G |
Mars1 |
methionyl-tRNA synthetase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of MARS1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:70,585,011...70,602,425
Ensembl chr 7:70,585,013...70,602,310
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G |
Mars2 |
methionyl-tRNA synthetase 2, mitochondrial |
decreases expression |
ISO |
Vincristine results in decreased expression of MARS2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 9:64,434,814...64,437,730
Ensembl chr 9:64,434,904...64,436,664 Ensembl chr 9:64,434,904...64,436,664
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G |
Matn2 |
matrilin 2 |
decreases response to substance |
ISO |
MATN2 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
|
NCBI chr 7:72,985,832...73,210,093
Ensembl chr 7:72,985,495...73,207,695
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G |
Matr3 |
matrin 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of MATR3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr18:28,351,691...28,390,764
Ensembl chr18:28,361,283...28,390,717
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G |
Max |
MYC associated factor X |
decreases expression |
ISO |
Vincristine results in decreased expression of MAX mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:99,984,260...100,011,460
Ensembl chr 6:99,984,260...100,011,388
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G |
Mbd4 |
methyl-CpG binding domain 4 DNA glycosylase |
decreases expression |
ISO |
Vincristine results in decreased expression of MBD4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:147,744,673...147,756,462
Ensembl chr 4:147,746,186...147,756,294
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G |
Mbnl3 |
muscleblind-like splicing regulator 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of MBNL3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:138,378,674...138,473,365
Ensembl chr X:138,384,912...138,435,391
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G |
Mbtd1 |
mbt domain containing 1 |
increases expression |
ISO |
Vincristine results in increased expression of MBTD1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:81,588,233...81,645,532
Ensembl chr10:81,592,114...81,642,663
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Mccc2 |
methylcrotonoyl-CoA carboxylase 2 |
increases expression |
ISO |
Vincristine results in increased expression of MCCC2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010
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Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
increases expression |
ISO |
Vincristine results in increased expression of MCL1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:197,786,212...197,788,992
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Mcm4 |
minichromosome maintenance complex component 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of MCM4 mRNA |
CTD |
PMID:23649840 |
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NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
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Mcmbp |
minichromosome maintenance complex binding protein |
increases expression |
ISO |
Vincristine results in increased expression of MCMBP mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:200,118,226...200,163,106
Ensembl chr 1:200,118,228...200,163,106
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Mcoln2 |
mucolipin TRP cation channel 2 |
increases expression |
ISO |
Vincristine results in increased expression of MCOLN2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:252,018,594...252,068,209
Ensembl chr 2:252,018,597...252,068,271
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Mdm2 |
MDM2 proto-oncogene |
increases expression decreases expression |
ISO |
Vincristine results in increased expression of MDM2 mRNA Vincristine results in decreased expression of MDM2 mRNA |
CTD |
PMID:16001973 PMID:23649840 |
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NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
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Mdn1 |
midasin AAA ATPase 1 |
increases expression |
ISO |
Vincristine results in increased expression of MDN1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:47,894,526...48,036,071
Ensembl chr 5:47,894,530...48,036,287
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Med29 |
mediator complex subunit 29 |
decreases expression |
ISO |
Vincristine results in decreased expression of MED29 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:85,368,288...85,373,691
Ensembl chr 1:85,368,288...85,373,099
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Med31 |
mediator complex subunit 31 |
decreases expression |
ISO |
Vincristine results in decreased expression of MED31 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:58,780,987...58,784,369
Ensembl chr10:58,780,597...58,784,374
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Mettl3 |
methyltransferase-like 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of METTL3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr15:28,710,299...28,721,491
Ensembl chr15:28,710,300...28,721,127
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Mfsd5 |
major facilitator superfamily domain containing 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of MFSD5 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 7:143,882,000...143,884,281
Ensembl chr 7:143,882,000...143,884,280
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Mfsd6 |
major facilitator superfamily domain containing 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of MFSD6 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:53,626,412...53,710,820
Ensembl chr 9:53,626,592...53,710,817
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Mga |
MAX dimerization protein MGA |
increases expression |
ISO |
Vincristine results in increased expression of MGA mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:111,669,645...111,760,822
Ensembl chr 3:111,699,021...111,759,911
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Mgat4a |
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A |
decreases expression |
ISO |
Vincristine results in decreased expression of MGAT4A mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:44,033,433...44,126,946
Ensembl chr 9:44,033,436...44,126,919
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Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions |
ISO |
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine; MGMT affects the susceptibility to [Procarbazine co-treated with Vincristine co-treated with Nitrosourea Compounds]; MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine] |
CTD |
PMID:11792417 PMID:16033832 PMID:16936459 |
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NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
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Mical3 |
microtubule associated monooxygenase, calponin and LIM domain containing 3 |
increases expression |
ISO |
Vincristine results in increased expression of MICAL3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:153,484,876...153,631,986
Ensembl chr 4:153,484,876...153,593,773
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Mir132 |
microRNA 132 |
increases expression |
ISO |
Vincristine results in increased expression of MIR132 mRNA |
CTD |
PMID:32505695 |
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NCBI chr10:62,014,995...62,015,095
Ensembl chr10:62,014,995...62,015,095
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Mir497 |
microRNA 497 |
multiple interactions |
ISO |
[MIR497 results in decreased expression of BCL2 protein] which results in increased susceptibility to Vincristine |
CTD |
PMID:21258880 |
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NCBI chr10:56,844,977...56,845,045
Ensembl chr10:56,844,977...56,845,045
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Mki67 |
marker of proliferation Ki-67 |
increases response to substance |
ISO |
MKI67 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:20864405 |
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NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
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Mkln1 |
muskelin 1 |
increases expression |
ISO |
Vincristine results in increased expression of MKLN1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:58,693,384...58,817,924
Ensembl chr 4:58,693,384...58,817,691
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Mknk2 |
MAPK interacting serine/threonine kinase 2 |
increases expression |
ISO |
Vincristine results in increased expression of MKNK2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
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Mllt3 |
MLLT3, super elongation complex subunit |
increases expression |
ISO |
Vincristine results in increased expression of MLLT3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:106,103,498...106,202,559
Ensembl chr 5:106,103,407...106,207,126
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G |
Mmd |
monocyte to macrophage differentiation-associated |
increases expression |
ISO |
Vincristine results in increased expression of MMD mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
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Mnd1 |
meiotic nuclear divisions 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of MND1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:183,073,029...183,140,768
Ensembl chr 2:183,073,187...183,128,932
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Mpz |
myelin protein zero |
increases response to substance |
ISO |
MPZ gene results in increased susceptibility to Vincristine |
CTD |
PMID:16676325 |
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NCBI chr13:89,524,204...89,530,070
Ensembl chr13:89,524,329...89,530,068
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Mr1 |
major histocompatibility complex, class I-related |
increases expression |
ISO |
Vincristine results in increased expression of MR1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
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Mrpl30 |
mitochondrial ribosomal protein L30 |
decreases expression |
ISO |
Vincristine results in decreased expression of MRPL30 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:44,483,809...44,496,116
Ensembl chr 9:44,483,875...44,571,331
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Mrpl39 |
mitochondrial ribosomal protein L39 |
decreases expression |
ISO |
Vincristine results in decreased expression of MRPL39 mRNA |
CTD |
PMID:23649840 |
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NCBI chr11:24,181,605...24,200,022
Ensembl chr11:24,181,658...24,199,968
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G |
Mrpl50 |
mitochondrial ribosomal protein L50 |
decreases expression |
ISO |
Vincristine results in decreased expression of MRPL50 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:64,784,164...64,789,318
Ensembl chr 5:64,784,170...64,789,318
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Mrps16 |
mitochondrial ribosomal protein S16 |
decreases expression |
ISO |
Vincristine results in decreased expression of MRPS16 mRNA |
CTD |
PMID:23649840 |
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NCBI chr15:4,351,292...4,353,694
Ensembl chr15:4,351,292...4,353,694
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Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
increases expression |
ISO |
Vincristine results in increased expression of ND6 mRNA |
CTD |
PMID:23649840 |
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NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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Mt2A |
metallothionein 2A |
increases expression |
ISO |
Vincristine results in increased expression of MT2A mRNA |
CTD |
PMID:23649840 |
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NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
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Mta3 |
metastasis associated 1 family, member 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of MTA3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 6:6,904,449...7,036,929
Ensembl chr 6:6,908,684...7,031,828
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Mtcp1 |
mature T-cell proliferation 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of MTCP1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:411,159...411,934
Ensembl chr18:411,455...411,849
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Mtfr2 |
mitochondrial fission regulator 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of MTFR2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:15,834,779...15,850,424
Ensembl chr 1:15,782,477...15,860,624
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G |
Mtg2 |
mitochondrial ribosome-associated GTPase 2 |
increases expression |
ISO |
Vincristine results in increased expression of MTG2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:175,448,214...175,464,109
Ensembl chr 3:175,450,979...175,464,117
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Mthfd2l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
decreases expression |
ISO |
Vincristine results in decreased expression of MTHFD2L mRNA |
CTD |
PMID:23649840 |
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NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
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Mtrf1l |
mitochondrial translation release factor 1 like |
decreases expression |
ISO |
Vincristine results in decreased expression of MTRF1L mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:42,475,791...42,485,999
Ensembl chr 1:42,475,792...42,486,035
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Mvp |
major vault protein |
increases expression |
ISO |
Vincristine results in increased expression of MVP mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:198,420,813...198,448,612
Ensembl chr 1:198,420,806...198,450,047
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Mxd1 |
max dimerization protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of MXD1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression increases expression |
ISO EXP |
Vincristine results in decreased expression of MYC mRNA Vincristine results in increased expression of MYC mRNA |
CTD |
PMID:16001973 PMID:20624997 |
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NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
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G |
Mycn |
MYCN proto-oncogene, bHLH transcription factor |
decreases response to substance multiple interactions |
ISO |
MYCN protein results in decreased susceptibility to Vincristine [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Vincristine |
CTD |
PMID:10348353 |
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NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
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Myh11 |
myosin heavy chain 11 |
increases expression |
ISO |
Vincristine results in increased expression of MYH11 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
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Mysm1 |
myb-like, SWIRM and MPN domains 1 |
increases expression |
ISO |
Vincristine results in increased expression of MYSM1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:113,902,115...113,939,083
Ensembl chr 5:113,906,803...113,939,127
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Mzb1 |
marginal zone B and B1 cell-specific protein |
decreases expression |
ISO |
Vincristine results in decreased expression of MZB1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:28,436,546...28,438,607
Ensembl chr18:28,436,548...28,438,654
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G |
N4bp2l2 |
NEDD4 binding protein 2-like 2 |
increases expression |
ISO |
Vincristine results in increased expression of N4BP2L2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr12:627,128...650,604
Ensembl chr12:628,488...650,376
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Naa25 |
N(alpha)-acetyltransferase 25, NatB auxiliary subunit |
decreases expression |
ISO |
Vincristine results in decreased expression of NAA25 mRNA |
CTD |
PMID:23649840 |
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NCBI chr12:40,628,005...40,680,421
Ensembl chr12:40,628,005...40,680,397
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Naa50 |
N(alpha)-acetyltransferase 50, NatE catalytic subunit |
decreases expression |
ISO |
Vincristine results in decreased expression of NAA50 mRNA |
CTD |
PMID:23649840 |
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NCBI chr11:61,508,162...61,530,830
Ensembl chr11:61,462,994...61,530,837
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G |
Nabp1 |
nucleic acid binding protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of NABP1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:55,049,893...55,057,784
Ensembl chr 9:55,050,203...55,057,658
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Naca |
nascent polypeptide associated complex subunit alpha |
decreases expression |
ISO |
Vincristine results in decreased expression of NACA mRNA |
CTD |
PMID:23649840 |
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NCBI chr 7:2,458,283...2,470,674
Ensembl chr 7:2,458,264...2,470,674
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Nampt |
nicotinamide phosphoribosyltransferase |
increases expression |
ISO |
Vincristine results in increased expression of NAMPT mRNA |
CTD |
PMID:23649840 |
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NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
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Napb |
NSF attachment protein beta |
increases expression |
ISO |
Vincristine results in increased expression of NAPB mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:143,017,571...143,063,904
Ensembl chr 3:143,020,454...143,063,983
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Nasp |
nuclear autoantigenic sperm protein |
decreases expression |
ISO |
Vincristine results in decreased expression of NASP mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
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Nbn |
nibrin |
increases expression |
EXP |
Vincristine results in increased expression of NBN mRNA |
CTD |
PMID:20624997 |
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NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
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G |
Ncbp1 |
nuclear cap binding protein subunit 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of NCBP1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 5:61,734,118...61,767,098
Ensembl chr 5:61,734,118...61,766,481
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Nceh1 |
neutral cholesterol ester hydrolase 1 |
increases expression |
ISO |
Vincristine results in increased expression of NCEH1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953
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Ncf2 |
neutrophil cytosolic factor 2 |
increases expression |
ISO |
Vincristine results in increased expression of NCF2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
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Ncoa7 |
nuclear receptor coactivator 7 |
increases expression |
ISO |
Vincristine results in increased expression of NCOA7 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
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Nde1 |
nudE neurodevelopment protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of NDE1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:860,513...904,624
Ensembl chr10:860,521...896,938
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G |
Ndufb4 |
NADH:ubiquinone oxidoreductase subunit B4 |
decreases expression |
ISO |
Vincristine results in decreased expression of NDUFB4 mRNA |
CTD |
PMID:23649840 |
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NCBI chr11:65,960,277...65,966,899
Ensembl chr11:65,960,277...65,966,898
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Neurl3 |
neuralized E3 ubiquitin protein ligase 3 |
increases expression |
ISO |
Vincristine results in increased expression of NEURL3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 9:42,831,737...42,841,765
Ensembl chr 9:42,831,742...42,839,837
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Nfat5 |
nuclear factor of activated T-cells 5 |
increases expression |
ISO |
Vincristine results in increased expression of NFAT5 mRNA |
CTD |
PMID:23649840 |
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NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
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G |
Nfatc2 |
nuclear factor of activated T-cells 2 |
increases response to substance |
ISO |
NFATC2 gene SNP results in increased susceptibility to Vincristine |
CTD |
PMID:21245421 |
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NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
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G |
Nfe2l1 |
nuclear factor, erythroid 2-like 1 |
increases expression |
ISO |
Vincristine results in increased expression of NFE2L1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
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G |
Nfe2l3 |
nuclear factor, erythroid 2-like 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of NFE2L3 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 4:81,205,214...81,233,068
Ensembl chr 4:81,205,404...81,232,813
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G |
Ngf |
nerve growth factor |
multiple interactions decreases response to substance |
EXP |
Bicuculline inhibits the reaction [Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]; Bicuculline inhibits the reaction [Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]; Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]; Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein] NGF protein results in decreased susceptibility to Vincristine; Vincristine results in decreased susceptibility to NGF protein |
CTD |
PMID:9524088 PMID:9622663 PMID:10553948 PMID:11991087 |
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NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
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Nhsl1 |
NHS-like 1 |
increases expression |
ISO |
Vincristine results in increased expression of NHSL1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:13,472,694...13,705,364
Ensembl chr 1:13,595,295...13,705,396
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Ninj1 |
ninjurin 1 |
increases expression |
ISO |
Vincristine results in increased expression of NINJ1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
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G |
Nisch |
nischarin |
decreases expression |
ISO |
Vincristine results in decreased expression of NISCH mRNA |
CTD |
PMID:23649840 |
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NCBI chr16:7,254,372...7,290,670
Ensembl chr16:7,254,974...7,290,561
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G |
Nmnat3 |
nicotinamide nucleotide adenylyltransferase 3 |
decreases response to substance |
ISO |
NMNAT3 protein results in decreased susceptibility to Vincristine |
CTD |
PMID:18463239 |
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NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
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G |
Nmrk2 |
nicotinamide riboside kinase 2 |
decreases response to substance |
ISO |
ITGB1BP3 mRNA results in decreased susceptibility to Vincristine |
CTD |
PMID:25199881 |
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NCBI chr 7:11,382,966...11,386,170
Ensembl chr 7:11,383,116...11,386,948
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G |
Nnt |
nicotinamide nucleotide transhydrogenase |
decreases expression |
ISO |
Vincristine results in decreased expression of NNT mRNA |
CTD |
PMID:23649840 |
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NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
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G |
Nol12 |
nucleolar protein 12 |
decreases expression |
ISO |
Vincristine results in decreased expression of NOL12 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 7:120,161,238...120,166,852
Ensembl chr 7:120,161,091...120,167,020
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G |
Nol4l |
nucleolar protein 4-like |
increases expression |
ISO |
Vincristine results in increased expression of NOL4L mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:148,905,677...148,940,426
Ensembl chr 3:148,909,826...148,932,878
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G |
Nos1 |
nitric oxide synthase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of NOS1 protein |
CTD |
PMID:16098672 |
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NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
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G |
Npl |
N-acetylneuraminate pyruvate lyase |
increases expression |
ISO |
Vincristine results in increased expression of NPL mRNA |
CTD |
PMID:23649840 |
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NCBI chr13:70,938,073...70,981,179
Ensembl chr13:70,938,082...70,980,913
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
Vincristine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 |
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NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions increases activity |
ISO |
[Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein] |
CTD |
PMID:20041327 |
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NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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G |
Nr2f2 |
nuclear receptor subfamily 2, group F, member 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of NR2F2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
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G |
Nr5a2 |
nuclear receptor subfamily 5, group A, member 2 |
increases expression |
ISO |
Vincristine results in increased expression of NR5A2 mRNA |
CTD |
PMID:23649840 |
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NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
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G |
Nrep |
neuronal regeneration related protein |
decreases expression |
ISO |
Vincristine results in decreased expression of NREP mRNA |
CTD |
PMID:23649840 |
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NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
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G |
Nrn1 |
neuritin 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of NRN1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr17:27,925,054...28,002,946
Ensembl chr17:27,925,057...27,969,433
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G |
Nsmce4a |
NSE4 homolog A, SMC5-SMC6 complex component |
decreases expression |
ISO |
Vincristine results in decreased expression of NSMCE4A mRNA |
CTD |
PMID:23649840 |
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NCBI chr 1:201,103,750...201,110,838
Ensembl chr 1:201,096,059...201,110,928
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G |
Nt5e |
5' nucleotidase, ecto |
increases expression |
ISO |
Vincristine results in increased expression of NT5E mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
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G |
Nudt7 |
nudix hydrolase 7 |
decreases expression |
ISO |
Vincristine results in decreased expression of NUDT7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:46,455,745...46,470,070
Ensembl chr19:46,455,761...46,482,050
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
increases expression |
ISO |
Vincristine results in increased expression of NUF2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
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G |
Numb |
NUMB, endocytic adaptor protein |
increases expression |
ISO |
Vincristine results in increased expression of NUMB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:107,279,917...107,325,345
Ensembl chr 6:107,279,920...107,325,345
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G |
Nup153 |
nucleoporin 153 |
increases expression |
ISO |
Vincristine results in increased expression of NUP153 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:18,358,712...18,411,368
Ensembl chr17:18,358,712...18,411,368
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G |
Nxt1 |
nuclear transport factor 2-like export factor 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of NXT1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:142,993,658...142,996,580
Ensembl chr 3:142,993,658...142,996,578
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G |
Oga |
O-GlcNAcase |
increases expression |
ISO |
Vincristine results in increased expression of OGA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
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G |
Ogg1 |
8-oxoguanine DNA glycosylase |
decreases expression |
ISO |
Vincristine results in decreased expression of OGG1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
decreases expression |
ISO |
Vincristine results in decreased expression of OGT mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:71,540,870...71,585,906
Ensembl chr X:71,528,988...71,585,908
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G |
Olah |
oleoyl-ACP hydrolase |
increases expression |
ISO |
Vincristine results in increased expression of OLAH mRNA |
CTD |
PMID:23649840 |
|
NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967
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G |
Orai1 |
ORAI calcium release-activated calcium modulator 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of ORAI1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:38,981,903...38,995,570
Ensembl chr12:38,981,927...38,995,570
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G |
Otp |
orthopedia homeobox |
increases expression |
ISO |
Vincristine results in increased expression of OTP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:24,546,393...24,554,953
Ensembl chr 2:24,546,536...24,554,683
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G |
P2rx5 |
purinergic receptor P2X 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of P2RX5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:59,725,438...59,737,126
Ensembl chr10:59,725,398...59,737,126
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G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Vincristine |
CTD |
PMID:16982702 |
|
NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
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G |
P4ha1 |
prolyl 4-hydroxylase subunit alpha 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of P4HA1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
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G |
Pabpc1l |
poly(A) binding protein, cytoplasmic 1-like |
decreases expression |
ISO |
Vincristine results in decreased expression of PABPC1L mRNA |
CTD |
PMID:23649840 |
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NCBI chr 3:160,410,733...160,447,073
Ensembl chr 3:160,410,757...160,444,940
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G |
Pabpn1 |
poly(A) binding protein, nuclear 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of PABPN1 mRNA |
CTD |
PMID:23649840 |
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NCBI chr15:33,555,640...33,560,251
Ensembl chr15:33,555,640...33,560,242
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G |
Paip1 |
poly(A) binding protein interacting protein 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of PAIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:52,300,921...52,328,212
Ensembl chr 2:52,301,798...52,328,205
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G |
Pank2 |
pantothenate kinase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of PANK2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:123,807,911...123,841,797
Ensembl chr 3:123,807,952...123,841,797
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G |
Paqr4 |
progestin and adipoQ receptor family member 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of PAQR4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:13,072,252...13,075,866
Ensembl chr10:13,070,146...13,075,864
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
[CEP 33779 results in increased susceptibility to Vincristine] which results in increased cleavage of PARP1 protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased cleavage of PARP1 protein |
CTD |
PMID:28669723 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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G |
Parp2 |
poly (ADP-ribose) polymerase 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of PARP2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:27,739,416...27,749,650
Ensembl chr15:27,739,251...27,749,648
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G |
Parp9 |
poly (ADP-ribose) polymerase family, member 9 |
increases expression |
ISO |
Vincristine results in increased expression of PARP9 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799
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G |
Patl1 |
PAT1 homolog 1, processing body mRNA decay factor |
decreases expression |
ISO |
Vincristine results in decreased expression of PATL1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:228,337,756...228,369,719
Ensembl chr 1:228,337,767...228,369,761
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G |
Pbxip1 |
PBX homeobox interacting protein 1 |
increases expression |
ISO |
Vincristine results in increased expression of PBXIP1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:188,763,887...188,776,445
Ensembl chr 2:188,766,535...188,776,439
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G |
Pced1b |
PC-esterase domain containing 1B |
decreases expression |
ISO |
Vincristine results in decreased expression of PCED1B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 7:138,707,426...138,846,127
Ensembl chr 7:138,707,426...138,846,123
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G |
Pcf11 |
PCF11 cleavage and polyadenylation factor subunit |
decreases expression |
ISO |
Vincristine results in decreased expression of PCF11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:157,463,014...157,494,134
Ensembl chr 1:157,468,626...157,494,008
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G |
Pcgf2 |
polycomb group ring finger 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of PCGF2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:85,631,829...85,642,591
Ensembl chr10:85,632,819...85,636,902
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G |
Pcnx1 |
pecanex 1 |
increases expression |
ISO |
Vincristine results in increased expression of PCNX1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 6:105,611,425...105,747,178
Ensembl chr 6:105,611,456...105,743,404
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G |
Pcnx2 |
pecanex 2 |
increases expression |
ISO |
Vincristine results in increased expression of PCNX2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr19:58,583,000...58,736,069
Ensembl chr19:58,583,632...58,735,173
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G |
Pcsk7 |
proprotein convertase subtilisin/kexin type 7 |
increases expression |
ISO |
Vincristine results in increased expression of PCSK7 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:50,200,069...50,222,655
Ensembl chr 8:50,200,069...50,222,630
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G |
Pdcd5 |
programmed cell death 5 |
decreases expression |
ISO |
Vincristine results in decreased expression of PDCD5 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801 Ensembl chr 1:91,173,473...91,178,801
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G |
Pde4b |
phosphodiesterase 4B |
increases expression |
ISO |
Vincristine results in increased expression of PDE4B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
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G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of PDK1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
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G |
Pdk3 |
pyruvate dehydrogenase kinase 3 |
decreases expression |
ISO |
Vincristine results in decreased expression of PDK3 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:62,836,131...62,904,114
Ensembl chr X:62,836,131...62,903,554
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G |
Pds5b |
PDS5 cohesin associated factor B |
increases expression |
ISO |
Vincristine results in increased expression of PDS5B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:659,995...794,042
Ensembl chr12:660,011...794,042
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G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
increases expression |
ISO |
Vincristine results in increased expression of PEA15 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
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G |
Peli1 |
pellino E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of PELI1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:106,008,086...106,062,566
Ensembl chr14:106,008,086...106,061,641
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G |
Pex11b |
peroxisomal biogenesis factor 11 beta |
decreases expression |
ISO |
Vincristine results in decreased expression of PEX11B mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 2:198,762,138...198,771,040
Ensembl chr 2:198,762,138...198,771,026
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G |
Pex13 |
peroxisomal biogenesis factor 13 |
decreases expression |
ISO |
Vincristine results in decreased expression of PEX13 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr14:108,394,299...108,411,994
Ensembl chr14:108,394,303...108,412,823
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G |
Pfas |
phosphoribosylformylglycinamidine synthase |
decreases expression |
ISO |
Vincristine results in decreased expression of PFAS mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:55,571,881...55,593,384
Ensembl chr10:55,571,118...55,589,978
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G |
Pfkfb4 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
decreases expression |
ISO |
Vincristine results in decreased expression of PFKFB4 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 8:117,733,347...117,776,525
Ensembl chr 8:117,737,117...117,775,386
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G |
Pgm1 |
phosphoglucomutase 1 |
decreases expression |
ISO |
Vincristine results in decreased expression of PGM1 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
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G |
Pgp |
phosphoglycolate phosphatase |
decreases expression |
ISO |
Vincristine results in decreased expression of PGP mRNA |
CTD |
PMID:23649840 |
|
NCBI chr10:13,836,105...13,838,731
Ensembl chr10:13,836,128...13,838,765
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G |
Phf11 |
PHD finger protein 11 |
increases expression |
ISO |
Vincristine results in increased expression of PHF11 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr15:38,692,817...39,683,417
Ensembl chr15:38,647,779...38,709,984
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G |
Phf6 |
PHD finger protein 6 |
decreases expression |
ISO |
Vincristine results in decreased expression of PHF6 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:158,698,353...158,739,855
Ensembl chr X:158,698,356...158,739,838 Ensembl chr X:158,698,356...158,739,838
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G |
Phtf2 |
putative homeodomain transcription factor 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of PHTF2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 4:10,823,191...10,938,273
Ensembl chr 4:10,823,281...10,938,318
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
increases expression |
ISO |
Vincristine results in increased expression of PIK3C2A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
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G |
Pik3r2 |
phosphoinositide-3-kinase regulatory subunit 2 |
decreases expression |
ISO |
Vincristine results in decreased expression of PIK3R2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr16:20,415,109...20,424,982
Ensembl chr16:20,416,432...20,424,980
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G |
Pilra |
paired immunoglobin-like type 2 receptor alpha |
increases expression |
ISO |
Vincristine results in increased expression of PILRA mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:21,412,598...21,418,621
Ensembl chr12:21,412,538...21,420,169
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G |
Pim2 |
Pim-2 proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Vincristine results in increased expression of PIM2 mRNA |
CTD |
PMID:23649840 |
|
NCBI chr X:15,462,621...15,467,890
Ensembl chr X:15,462,016...15,467,875
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G |
Pitpnb |
phosphatidylinositol transfer protein, beta |
decreases expression |
ISO |
Vincristine results in decreased expression of PITPNB mRNA |
CTD |
PMID:23649840 |
|
NCBI chr12:51,279,194...51,341,752
Ensembl chr12:51,280,150...51,341,716
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G |
Pkig |
cAMP-dependent protein kinase inhibitor gamma |
increases expression |
ISO |
Vincristine results in increased expression of PKIG mRNA |
CTD |
PMID:23649840 |
|
NCBI chr 3:160,047,257...160,115,180
Ensembl chr 3:160,047,296...160,115,177
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G |
Pla1a |
phospholipase A1 member A |
increases expression |
ISO |
Vincristine results in increased expression of PLA1A mRNA |
CTD |
PMID:23649840 |
|
NCBI chr11:64,882,024...64,919,714
Ensembl chr11:64,882,288...64,919,579
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G |
Pla2g4c |
phospholipase A2 group IVC |
increases expression |
ISO |
|