Advanced Search (OLGA)

Gene: Efcab7 (EF-hand calcium binding domain 7) Rattus norvegicus

Analyze

Symbol:

Efcab7

Name:

EF-hand calcium binding domain 7

RGD ID:

1561825

Description:

Predicted to enable calcium ion binding activity. Predicted to be involved in several processes, including positive regulation of protein localization; positive regulation of transcription by RNA polymerase II; and protein localization to motile cilium. Predicted to be located in cytoplasmic side of plasma membrane. Predicted to be part of plasma membrane protein complex. Predicted to be active in ciliary membrane. Orthologous to human EFCAB7 (EF-hand calcium binding domain 7); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; Cuprizon.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

EF-hand calcium-binding domain-containing protein 7; LOC362549; RGD1561825; similar to CDNA sequence BC020077

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EFCAB7 (EF-hand calcium binding domain 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Efcab7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Efcab7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EFCAB7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EFCAB7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Efcab7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EFCAB7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EFCAB7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Efcab7 (EF-hand calcium binding domain 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	EFCAB7 (EF-hand calcium binding domain 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Efcab7 (EF-hand calcium binding domain 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	efcab7 (EF-hand calcium binding domain 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T02G5.3	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	119,640,841 - 119,691,566 (+)	NCBI		GRCr8
mRatBN7.2	5	114,525,403 - 114,576,130 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	114,525,167 - 114,576,129 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	117,081,727 - 117,132,281 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	118,807,048 - 118,857,604 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	118,869,583 - 118,920,138 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	118,673,835 - 118,724,581 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	118,541,979 - 118,724,581 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	122,591,957 - 122,629,531 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	5	122,470,265 - 122,472,469 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	120,525,527 - 120,576,068 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	113,073,505 - 113,124,027 (+)	NCBI		Celera
Cytogenetic Map	5	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation It (ISO)

Craniosynostosis Syndrome, Autosomal Recessive (ISO)

intellectual disability (ISO)

Postaxial Polydactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aflatoxin M1 (ISO)

alcohol (ISO)

arsane (ISO)

arsenic atom (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

calcitriol (ISO)

chlorpyrifos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

FR900359 (ISO)

hydrogen peroxide (ISO)

lipopolysaccharide (ISO)

methyl methanesulfonate (ISO)

oxaliplatin (EXP)

paclitaxel (ISO)

paracetamol (EXP)

quercetin (ISO)

quinolin-8-ol (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

succimer (ISO)

sunitinib (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

vinclozolin (EXP)

vismodegib (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of protein import into nucleus (IEA,ISO)

positive regulation of protein localization to ciliary membrane (IBA,IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

protein localization to motile cilium (IEA,ISO)

regulation of smoothened signaling pathway (IEA,ISO)

Cellular Component

ciliary membrane (IBA,IEA,ISO)

cytoplasmic side of plasma membrane (IEA,ISO)

membrane (IEA)

plasma membrane protein complex (IBA,IEA,ISO)

Molecular Function

calcium ion binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:24582806

Genomics

Comparative Map Data

Efcab7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	119,640,841 - 119,691,566 (+)	NCBI		GRCr8
mRatBN7.2	5	114,525,403 - 114,576,130 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	114,525,167 - 114,576,129 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	117,081,727 - 117,132,281 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	118,807,048 - 118,857,604 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	118,869,583 - 118,920,138 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	118,673,835 - 118,724,581 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	118,541,979 - 118,724,581 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	122,591,957 - 122,629,531 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	5	122,470,265 - 122,472,469 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	120,525,527 - 120,576,068 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	113,073,505 - 113,124,027 (+)	NCBI		Celera
Cytogenetic Map	5	q33	NCBI

EFCAB7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	63,523,525 - 63,585,370 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	63,523,372 - 63,572,693 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	63,989,196 - 64,038,364 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	63,761,856 - 63,810,952 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	62,278,938 - 62,328,273 (+)	NCBI		Celera
Cytogenetic Map	1	p31.3	NCBI
HuRef	1	62,097,101 - 62,146,337 (+)	NCBI		HuRef
CHM1_1	1	64,104,820 - 64,154,155 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	63,399,112 - 63,465,319 (+)	NCBI		T2T-CHM13v2.0

Efcab7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	99,717,440 - 99,769,985 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	99,717,435 - 99,769,985 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	99,829,445 - 99,912,788 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	99,829,198 - 99,912,788 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	99,550,648 - 99,585,390 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	99,375,977 - 99,410,717 (+)	NCBI		MGSCv36	mm8
Celera	4	98,205,751 - 98,257,285 (+)	NCBI		Celera
Cytogenetic Map	4	C6	NCBI
cM Map	4	45.71	NCBI

Efcab7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	26,474,568 - 26,509,196 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	26,473,310 - 26,510,704 (-)	NCBI	ChiLan1.0	ChiLan1.0

EFCAB7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	163,281,065 - 163,330,396 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	162,431,674 - 162,480,895 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	62,779,937 - 62,829,252 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	64,588,691 - 64,650,754 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	64,588,691 - 64,638,005 (+)	Ensembl	panpan1.1		panPan2

EFCAB7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	46,598,411 - 46,645,651 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	46,597,432 - 46,645,592 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	46,659,205 - 46,706,543 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	46,778,686 - 46,826,225 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	46,778,693 - 46,826,040 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	46,740,499 - 46,787,825 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	46,686,845 - 46,734,339 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	46,944,328 - 46,991,657 (-)	NCBI		UU_Cfam_GSD_1.0

Efcab7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	76,776,487 - 76,822,052 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936692	1,091,613 - 1,137,671 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936692	1,091,872 - 1,137,426 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EFCAB7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	148,851,183 - 148,994,952 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	148,939,050 - 148,997,790 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	137,259,099 - 137,317,498 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EFCAB7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	69,504,889 - 69,564,538 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	69,517,867 - 69,562,294 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	47,896,943 - 47,947,384 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Efcab7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	30,605,865 - 30,637,383 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624742	30,607,384 - 30,639,187 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Efcab7
401 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	16
Count of miRNA genes:	14
Interacting mature miRNAs:	16
Transcripts:	ENSRNOT00000013089
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
7794743	Bp373	Blood pressure QTL 373		0.0058	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	112175546	116047089	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	79584860	124584860	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	87468046	132468046	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	79584860	124584860	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
1582212	Livw2	Liver weight QTL 2	3.5	0.0004	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	5	99016066	119085810	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	87468046	132468046	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	87468046	132468046	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	79584860	124584860	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	90067849	128034027	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55805606	132207589	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
631527	Tls1	T-lymphoma susceptibility QTL 1	0	0.001	thymus integrity trait (VT:0010555)	post-insult time to onset of T-cell lymphoma (CMO:0001907)	5	90450144	135450144	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84132602	129132602	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	66174080	124160948	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	58829236	128034027	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	87765973	132765973	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	90067849	128034027	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763886	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010066420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000013089 ⟹ ENSRNOP00000013089

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	114,525,571 - 114,576,127 (+)	Ensembl
Rnor_6.0 Ensembl	5	118,541,979 - 118,724,581 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103769 ⟹ ENSRNOP00000085104

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	114,527,607 - 114,576,129 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106347 ⟹ ENSRNOP00000076772

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	114,525,167 - 114,576,129 (+)	Ensembl

RefSeq Acc Id:

NM_001191866 ⟹ NP_001178795

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,641,025 - 119,691,565 (+)	NCBI
mRatBN7.2	5	114,525,589 - 114,576,129 (+)	NCBI
Rnor_6.0	5	118,674,041 - 118,724,581 (+)	NCBI
Rnor_5.0	5	122,470,265 - 122,472,469 (+)	NCBI
Rnor_5.0	5	122,591,957 - 122,629,531 (+)	NCBI
Celera	5	113,073,505 - 113,124,027 (+)	NCBI

Sequence:

show sequence

AAAAAGGCGGAGGTCTGTCGGGTTGCGCTGAGAGGTTCGCGGAACTACTAAAGAAAATTGGCTG
CTCTTCTTGGTTTGTGAGCTGAAATTAGAATGGCCAGCAATCCTGGAAGTGATGCAGCTTTGGA
TACTCAGAAGTCAGTGCTTTCAGGGAGTCCTCGAACAAAGAAATTCCCACTAACTGAACAGGAG
GTATTTTATATGAATTGTAGAGCCGCCTACTTAACCATCTTCAAAAGCAGCTTGGAAAACATTA
TGTCTAAAGATCAACTCTACTTAGCTCTTCAGCATGCAGGAAGAAATCCATCTCAAAAGACCAT
TAATAAGTATTGGACTCCTCAAACTGCCAAACTAAATTTTGATGATTTTTGTATAATTTTAAGC
AAGGAAAAACCTACTTCGAAAGCAGACTTACTAAAATCATTTAAACAATTAGATGTAAATGATG
ATGGCTCTATCCTACACTCTGACCTTCATAAATATCTAACCAAGAGAGGTGAGAAGATGACTCA
GGAAGAAGTAAATGCTGTAATAAGTTTGGCTGATGTAAATGCTAATGGAAAGTTTGACTACGTT
AAGTTTTGTAAATTATACATGGCAACCAGTGAGCAGTGTCTCAAGACTACACTAGAAAGACTGG
AGGCCGACAGTAAACTGAGGCGTCAACAGTTTGGAAGCCAAATGGAAGGGTCCCCTGAAAGGGA
TCCATCACCAGTACCAAAACCATCACCTAGGATCATAAGAAAAAATGACCAAGAAACGTTCTCA
AGCAAAGGTGACACAAGCCACACCTTACTGTCAACAACTAGAAAGTTCAAGACATCTGTTTCCT
TCACAATGCCTATGAGCGCTAACAGTAACCGAGACTCAACATTAACTGAACCAAACTTAAAGGA
TTGGCAGTGTGCACAATCAAGAGGCTGCTTCTTTTTAGAGGAAGATGGTGAAGTTGTCAGTCAT
CAGTACAAAATGCACATAGCTCAGAGATCTGTGCTTTACCTGACAATTAAGCCATTGAATCTGA
GTCAAGTTGAAGGAAAACATTCTCCCTGGTTATCGGTTGATACAGCCTTATATATTCTTAAGAA
AAATGAGAATCCAGCAGAGGCACAGCTCATGTGTTTTACCGAACTACGAAACAGAGAAGTGTTT
GGATGGACTGGTGAACTAGAACCAGGAATTTATTGGCTAATTCCTTCCACAACTGGATGTAGGC
TAAGAAAAGAAACAAAACCAGTAACAGAAGAAGTCCAACTTGTACATAGAGATGAAACAGGGGA
ATTATCTCTTACAAGTGAGTTTAGGTCAACTCTATCAGAGATATTTGAAATAATTGATTTAGAT
GGCAATGGTCTTATTAGCCTTGAAGAGTACAATTTTTTTGAGTTGAGAACAAGTGGTGAAAAGT
GTGATGAGGACGCTTGGGCTGTCTGCAGAGAAAACTTTGACACAAAGAAGAATGAATTAACAAG
ACAGGGCTTTATGGACTTGCATCTAATGGAAGCAAATGACCGAGAAGGAGACCCTCTTGACCTG
TGGGTGACTCTACATTCCATGGGCTACAATACGGCTCTGGAGCTGACAGAGGCATGCCCGTTTG
TCATCAATGTCTATGCAGAAAGGTGCAAGCCAAGGATTAAAGCTGTGCATATGGAGGCATGCAG
TGGGCAGCTTGAGAGGGCCATTTGCAAATCTGTCCTTGATAGAAGCAATGCTAAAGTCATGGAT
GGCTATGAGAATATAGTCGTGCACACTTGCAATCAAGACTCATGGATAACATCAATTATTGAAA
ATAAGTCAGATGACAAAGTGATTATTCACATCAACAATGAACTGAGTAAAAACTGTGTCAACAA
CAGAGGACTCAACATCTTTGCAGTAGAAGTGGCACCAAGATCTACAATGGTTTGTCAACATGTA
ATGCCCCTGAATGAGGAACAAGAATGGATATATTGTTGTGTGTATTCTCTTGTATCTTAAAGAA
TTCCATTTGGAGCTATCAAGCTAAGAAGTATTTTAGATCAAATATTTTATTTATTAACTACATG
CTTTTCCATGTAACTGGTATACTTAATAATCTGTTTCATTTCTATGCATTTATATTTTATGTCC
ATGTTATATATTTTATTATTAAAATACAAATAGTGTTTTAAAAGT

hide sequence

RefSeq Acc Id:

XM_008763885 ⟹ XP_008762107

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,640,841 - 119,691,566 (+)	NCBI
mRatBN7.2	5	114,525,403 - 114,576,130 (+)	NCBI
Rnor_6.0	5	118,673,835 - 118,724,576 (+)	NCBI

Sequence:

show sequence

AAGGCCAGAACCCATCTAGCCCCAGCCGCGTGCAGCACACGACCCTCTCTCACTATCCTGGACA
TACCAGCCTCCCAAAGGATAAGCTACAATGCCATGACTGTTTTCTGTCGGTCAATAGTCCACAG
ATCTCTAGTCGGAGCGTTTGGAAGAATGGCCAGCAATCCTGGAAGTGATGCAGCTTTGGATACT
CAGAAGTCAGTGCTTTCAGGGAGTCCTCGAACAAAGAAATTCCCACTAACTGAACAGGAGGTAT
TTTATATGAATTGTAGAGCCGCCTACTTAACCATCTTCAAAAGCAGCTTGGAAAACATTATGTC
TAAAGATCAACTCTACTTAGCTCTTCAGCATGCAGGAAGAAATCCATCTCAAAAGACCATTAAT
AAGTATTGGACTCCTCAAACTGCCAAACTAAATTTTGATGATTTTTGTATAATTTTAAGCAAGG
AAAAACCTACTTCGAAAGCAGACTTACTAAAATCATTTAAACAATTAGATGTAAATGATGATGG
CTCTATCCTACACTCTGACCTTCATAAATATCTAACCAAGAGAGGTGAGAAGATGACTCAGGAA
GAAGTAAATGCTGTAATAAGTTTGGCTGATGTAAATGCTAATGGAAAGTTTGACTACGTTAAGT
TTTGTAAATTATACATGGCAACCAGTGAGCAGTGTCTCAAGACTACACTAGAAAGACTGGAGGC
CGACAGTAAACTGAGGCGTCAACAGTTTGGAAGCCAAATGGAAGGGTCCCCTGAAAGGGATCCA
TCACCAGTACCAAAACCATCACCTAGGATCATAAGAAAAAATGACCAAGAAACGTTCTCAAGCA
AAGGTGACACAAGCCACACCTTACTGTCAACAACTAGAAAGTTCAAGACATCTGTTTCCTTCAC
AATGCCTATGAGCGCTAACAGTAACCGAGACTCAACATTAACTGAACCAAACTTAAAGGATTGG
CAGTGTGCACAATCAAGAGGCTGCTTCTTTTTAGAGGAAGATGGTGAAGTTGTCAGTCATCAGT
ACAAAATGCACATAGCTCAGAGATCTGTGCTTTACCTGACAATTAAGCCATTGAATCTGAGTCA
AGTTGAAGGAAAACATTCTCCCTGGTTATCGGTTGATACAGCCTTATATATTCTTAAGAAAAAT
GAGAATCCAGCAGAGGCACAGCTCATGTGTTTTACCGAACTACGAAACAGAGAAGTGTTTGGAT
GGACTGGTGAACTAGAACCAGGAATTTATTGGCTAATTCCTTCCACAACTGGATGTAGGCTAAG
AAAAGAAACAAAACCAGTAACAGAAGAAGTCCAACTTGTACATAGAGATGAAACAGGGGAATTA
TCTCTTACAAGTGAGTTTAGGTCAACTCTATCAGAGATATTTGAAATAATTGATTTAGATGGCA
ATGGTCTTATTAGCCTTGAAGAGTACAATTTTTTTGAGTTGAGAACAAGTGGTGAAAAGTGTGA
TGAGGACGCTTGGGCTGTCTGCAGAGAAAACTTTGACACAAAGAAGAATGAATTAACAAGACAG
GGCTTTATGGACTTGCATCTAATGGAAGCAAATGACCGAGAAGGAGACCCTCTTGACCTGTGGG
TGACTCTACATTCCATGGGCTACAATACGGCTCTGGAGCTGACAGAGGCATGCCCGTTTGTCAT
CAATGTCTATGCAGAAAGGTGCAAGCCAAGGATTAAAGCTGTGCATATGGAGGCATGCAGTGGG
CAGCTTGAGAGGGCCATTTGCAAATCTGTCCTTGATAGAAGCAATGCTAAAGTCATGGATGGCT
ATGAGAATATAGTCGTGCACACTTGCAATCAAGACTCATGGATAACATCAATTATTGAAAATAA
GTCAGATGACAAAGTGATTATTCACATCAACAATGAACTGAGTAAAAACTGTGTCAACAACAGA
GGACTCAACATCTTTGCAGTAGAAGTGGCACCAAGATCTACAATGGTTTGTCAACATGTAATGC
CCCTGAATGAGGAACAAGAATGGATATATTGTTGTGTGTATTCTCTTGTATCTTAAAGAATTCC
ATTTGGAGCTATCAAGCTAAGAAGTATTTTAGATCAAATATTTTATTTATTAACTACATGCTTT
TCCATGTAACTGGTATACTTAATAATCTGTTTCATTTCTATGCATTTATATTTTATGTCCATGT
TATATATTTTATTATTAAAATACAAATAGTGTTTTA

hide sequence

RefSeq Acc Id:

XM_008763886 ⟹ XP_008762108

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,640,878 - 119,691,566 (+)	NCBI
mRatBN7.2	5	114,525,447 - 114,576,130 (+)	NCBI
Rnor_6.0	5	118,673,953 - 118,724,576 (+)	NCBI

Sequence:

show sequence

TAGTCCACAGATCTCTAGTCGGAGCGTTTGGAAGGTGCTCTGCCTCTTACTTCCGGTGGCGGGG
AAGCGCAGTTGCTATGAATGGCCAGCAATCCTGGAAGTGATGCAGCTTTGGATACTCAGAAGTC
AGTGCTTTCAGGGAGTCCTCGAACAAAGAAATTCCCACTAACTGAACAGGAGGTATTTTATATG
AATTGTAGAGCCGCCTACTTAACCATCTTCAAAAGCAGCTTGGAAAACATTATGTCTAAAGATC
AACTCTACTTAGCTCTTCAGCATGCAGGAAGAAATCCATCTCAAAAGACCATTAATAAGTATTG
GACTCCTCAAACTGCCAAACTAAATTTTGATGATTTTTGTATAATTTTAAGCAAGGAAAAACCT
ACTTCGAAAGCAGACTTACTAAAATCATTTAAACAATTAGATGTAAATGATGATGGCTCTATCC
TACACTCTGACCTTCATAAATATCTAACCAAGAGAGGTGAGAAGATGACTCAGGAAGAAGTAAA
TGCTGTAATAAGTTTGGCTGATGTAAATGCTAATGGAAAGTTTGACTACGTTAAGTTTTGTAAA
TTATACATGGCAACCAGTGAGCAGTGTCTCAAGACTACACTAGAAAGACTGGAGGCCGACAGTA
AACTGAGGCGTCAACAGTTTGGAAGCCAAATGGAAGGGTCCCCTGAAAGGGATCCATCACCAGT
ACCAAAACCATCACCTAGGATCATAAGAAAAAATGACCAAGAAACGTTCTCAAGCAAAGGTGAC
ACAAGCCACACCTTACTGTCAACAACTAGAAAGTTCAAGACATCTGTTTCCTTCACAATGCCTA
TGAGCGCTAACAGTAACCGAGACTCAACATTAACTGAACCAAACTTAAAGGATTGGCAGTGTGC
ACAATCAAGAGGCTGCTTCTTTTTAGAGGAAGATGGTGAAGTTGTCAGTCATCAGTACAAAATG
CACATAGCTCAGAGATCTGTGCTTTACCTGACAATTAAGCCATTGAATCTGAGTCAAGTTGAAG
GAAAACATTCTCCCTGGTTATCGGTTGATACAGCCTTATATATTCTTAAGAAAAATGAGAATCC
AGCAGAGGCACAGCTCATGTGTTTTACCGAACTACGAAACAGAGAAGTGTTTGGATGGACTGGT
GAACTAGAACCAGGAATTTATTGGCTAATTCCTTCCACAACTGGATGTAGGCTAAGAAAAGAAA
CAAAACCAGTAACAGAAGAAGTCCAACTTGTACATAGAGATGAAACAGGGGAATTATCTCTTAC
AAGTGAGTTTAGGTCAACTCTATCAGAGATATTTGAAATAATTGATTTAGATGGCAATGGTCTT
ATTAGCCTTGAAGAGTACAATTTTTTTGAGTTGAGAACAAGTGGTGAAAAGTGTGATGAGGACG
CTTGGGCTGTCTGCAGAGAAAACTTTGACACAAAGAAGAATGAATTAACAAGACAGGGCTTTAT
GGACTTGCATCTAATGGAAGCAAATGACCGAGAAGGAGACCCTCTTGACCTGTGGGTGACTCTA
CATTCCATGGGCTACAATACGGCTCTGGAGCTGACAGAGGCATGCCCGTTTGTCATCAATGTCT
ATGCAGAAAGGTGCAAGCCAAGGATTAAAGCTGTGCATATGGAGGCATGCAGTGGGCAGCTTGA
GAGGGCCATTTGCAAATCTGTCCTTGATAGAAGCAATGCTAAAGTCATGGATGGCTATGAGAAT
ATAGTCGTGCACACTTGCAATCAAGACTCATGGATAACATCAATTATTGAAAATAAGTCAGATG
ACAAAGTGATTATTCACATCAACAATGAACTGAGTAAAAACTGTGTCAACAACAGAGGACTCAA
CATCTTTGCAGTAGAAGTGGCACCAAGATCTACAATGGTTTGTCAACATGTAATGCCCCTGAAT
GAGGAACAAGAATGGATATATTGTTGTGTGTATTCTCTTGTATCTTAAAGAATTCCATTTGGAG
CTATCAAGCTAAGAAGTATTTTAGATCAAATATTTTATTTATTAACTACATGCTTTTCCATGTA
ACTGGTATACTTAATAATCTGTTTCATTTCTATGCATTTATATTTTATGTCCATGTTATATATT
TTATTATTAAAATACAAATAGTGTTTTA

hide sequence

RefSeq Acc Id:

XM_039110289 ⟹ XP_038966217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,640,997 - 119,691,566 (+)	NCBI
mRatBN7.2	5	114,525,561 - 114,576,130 (+)	NCBI

RefSeq Acc Id:

XM_039110290 ⟹ XP_038966218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,643,042 - 119,691,566 (+)	NCBI
mRatBN7.2	5	114,525,662 - 114,576,130 (+)	NCBI

RefSeq Acc Id:

XM_039110291 ⟹ XP_038966219

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,640,841 - 119,672,509 (+)	NCBI
mRatBN7.2	5	114,525,403 - 114,557,141 (+)	NCBI

RefSeq Acc Id:

XR_010066420

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	119,640,841 - 119,672,509 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178795	(Get FASTA)	NCBI Sequence Viewer
	XP_008762107	(Get FASTA)	NCBI Sequence Viewer
	XP_008762108	(Get FASTA)	NCBI Sequence Viewer
	XP_038966217	(Get FASTA)	NCBI Sequence Viewer
	XP_038966218	(Get FASTA)	NCBI Sequence Viewer
	XP_038966219	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL97816	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013089.5
	ENSRNOP00000076772
	ENSRNOP00000076772.1
	ENSRNOP00000085104.1

RefSeq Acc Id:

NP_001178795 ⟸ NM_001191866

- UniProtKB:

D3ZZK0 (UniProtKB/TrEMBL), A0A8I6A396 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASNPGSDAALDTQKSVLSGSPRTKKFPLTEQEVFYMNCRAAYLTIFKSSLENIMSKDQLYLAL
QHAGRNPSQKTINKYWTPQTAKLNFDDFCIILSKEKPTSKADLLKSFKQLDVNDDGSILHSDLH
KYLTKRGEKMTQEEVNAVISLADVNANGKFDYVKFCKLYMATSEQCLKTTLERLEADSKLRRQQ
FGSQMEGSPERDPSPVPKPSPRIIRKNDQETFSSKGDTSHTLLSTTRKFKTSVSFTMPMSANSN
RDSTLTEPNLKDWQCAQSRGCFFLEEDGEVVSHQYKMHIAQRSVLYLTIKPLNLSQVEGKHSPW
LSVDTALYILKKNENPAEAQLMCFTELRNREVFGWTGELEPGIYWLIPSTTGCRLRKETKPVTE
EVQLVHRDETGELSLTSEFRSTLSEIFEIIDLDGNGLISLEEYNFFELRTSGEKCDEDAWAVCR
ENFDTKKNELTRQGFMDLHLMEANDREGDPLDLWVTLHSMGYNTALELTEACPFVINVYAERCK
PRIKAVHMEACSGQLERAICKSVLDRSNAKVMDGYENIVVHTCNQDSWITSIIENKSDDKVIIH
INNELSKNCVNNRGLNIFAVEVAPRSTMVCQHVMPLNEEQEWIYCCVYSLVS

hide sequence

RefSeq Acc Id:	XP_008762107 ⟸ XM_008763885
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y0R4 (UniProtKB/TrEMBL), A0A8I6A396 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTVFCRSIVHRSLVGAFGRMASNPGSDAALDTQKSVLSGSPRTKKFPLTEQEVFYMNCRAAYLT IFKSSLENIMSKDQLYLALQHAGRNPSQKTINKYWTPQTAKLNFDDFCIILSKEKPTSKADLLK SFKQLDVNDDGSILHSDLHKYLTKRGEKMTQEEVNAVISLADVNANGKFDYVKFCKLYMATSEQ CLKTTLERLEADSKLRRQQFGSQMEGSPERDPSPVPKPSPRIIRKNDQETFSSKGDTSHTLLST TRKFKTSVSFTMPMSANSNRDSTLTEPNLKDWQCAQSRGCFFLEEDGEVVSHQYKMHIAQRSVL YLTIKPLNLSQVEGKHSPWLSVDTALYILKKNENPAEAQLMCFTELRNREVFGWTGELEPGIYW LIPSTTGCRLRKETKPVTEEVQLVHRDETGELSLTSEFRSTLSEIFEIIDLDGNGLISLEEYNF FELRTSGEKCDEDAWAVCRENFDTKKNELTRQGFMDLHLMEANDREGDPLDLWVTLHSMGYNTA LELTEACPFVINVYAERCKPRIKAVHMEACSGQLERAICKSVLDRSNAKVMDGYENIVVHTCNQ DSWITSIIENKSDDKVIIHINNELSKNCVNNRGLNIFAVEVAPRSTMVCQHVMPLNEEQEWIYC CVYSLVS hide sequence

RefSeq Acc Id:	XP_008762108 ⟸ XM_008763886
- Peptide Label:	isoform X2
- UniProtKB:	D3ZZK0 (UniProtKB/TrEMBL), A0A8I6A396 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASNPGSDAALDTQKSVLSGSPRTKKFPLTEQEVFYMNCRAAYLTIFKSSLENIMSKDQLYLAL QHAGRNPSQKTINKYWTPQTAKLNFDDFCIILSKEKPTSKADLLKSFKQLDVNDDGSILHSDLH KYLTKRGEKMTQEEVNAVISLADVNANGKFDYVKFCKLYMATSEQCLKTTLERLEADSKLRRQQ FGSQMEGSPERDPSPVPKPSPRIIRKNDQETFSSKGDTSHTLLSTTRKFKTSVSFTMPMSANSN RDSTLTEPNLKDWQCAQSRGCFFLEEDGEVVSHQYKMHIAQRSVLYLTIKPLNLSQVEGKHSPW LSVDTALYILKKNENPAEAQLMCFTELRNREVFGWTGELEPGIYWLIPSTTGCRLRKETKPVTE EVQLVHRDETGELSLTSEFRSTLSEIFEIIDLDGNGLISLEEYNFFELRTSGEKCDEDAWAVCR ENFDTKKNELTRQGFMDLHLMEANDREGDPLDLWVTLHSMGYNTALELTEACPFVINVYAERCK PRIKAVHMEACSGQLERAICKSVLDRSNAKVMDGYENIVVHTCNQDSWITSIIENKSDDKVIIH INNELSKNCVNNRGLNIFAVEVAPRSTMVCQHVMPLNEEQEWIYCCVYSLVS hide sequence

Ensembl Acc Id:

ENSRNOP00000013089 ⟸ ENSRNOT00000013089

RefSeq Acc Id:	XP_038966219 ⟸ XM_039110291
- Peptide Label:	isoform X4
- UniProtKB:	A6JRM4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038966217 ⟸ XM_039110289
- Peptide Label:	isoform X2
- UniProtKB:	D3ZZK0 (UniProtKB/TrEMBL), A0A8I6A396 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038966218 ⟸ XM_039110290
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6A396 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085104 ⟸ ENSRNOT00000103769

Ensembl Acc Id:

ENSRNOP00000076772 ⟸ ENSRNOT00000106347

Protein Domains

EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZZK0-F1-model_v2	AlphaFold	D3ZZK0	1-628	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561825	AgrOrtholog
BioCyc Gene	G2FUF-40564	BioCyc
Ensembl Genes	ENSRNOG00000009782	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013089.7	UniProtKB/TrEMBL
	ENSRNOT00000103769.1	UniProtKB/TrEMBL
	ENSRNOT00000106347	ENTREZGENE
	ENSRNOT00000106347.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-like_dom	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_Ca-bd	UniProtKB/TrEMBL
	Miro-EF-hand_domain	UniProtKB/TrEMBL
KEGG Report	rno:362549	UniProtKB/TrEMBL
NCBI Gene	362549	ENTREZGENE
PANTHER	EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7	UniProtKB/TrEMBL
	EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7	UniProtKB/TrEMBL
Pfam	EF-hand_7	UniProtKB/TrEMBL
	EF_hand_3	UniProtKB/TrEMBL
PhenoGen	Efcab7	PhenoGen
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000009782	RatGTEx
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A8I5Y0R4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A396	ENTREZGENE, UniProtKB/TrEMBL
	A6JRM4	ENTREZGENE, UniProtKB/TrEMBL
	D3ZZK0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-29	Efcab7	EF-hand calcium binding domain 7	RGD1561825_predicted	similar to CDNA sequence BC020077 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1561825_predicted	similar to CDNA sequence BC020077 (predicted)	LOC362549	similar to CDNA sequence BC020077	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC362549	similar to CDNA sequence BC020077			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar