Gene: Dock8 (dedicator of cytokinesis 8) Rattus norvegicus
Symbol: Dock8
Name: dedicator of cytokinesis 8
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN cellular response to chemokine (ortholog); dendritic cell migration (ortholog); immunological synapse formation (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); Intellectual Disability (ortholog); Job Syndrome (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); leading edge membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dedicator of cytokinesis protein 8; LOC499337; MGC116414; similar to dedicator of cytokinesis 8
Homo sapiens (human) : DOCK8 (dedicator of cytokinesis 8)  HGNC  AGR
Mus musculus (house mouse) : Dock8 (dedicator of cytokinesis 8)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Dock8 (dedicator of cytokinesis 8)
Pan paniscus (bonobo/pygmy chimpanzee) : DOCK8 (dedicator of cytokinesis 8)
Canis lupus familiaris (dog) : DOCK8 (dedicator of cytokinesis 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dock8 (dedicator of cytokinesis 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01242,934,685 - 243,153,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01250,200,507 - 250,417,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,441,384 - 228,634,717 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1219,852,410 - 220,042,463 (+)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Dock8
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561588
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE