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Gene: Mccc2 (methylcrotonoyl-CoA carboxylase 2) Rattus norvegicus
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Symbol: Mccc2
Name: methylcrotonoyl-CoA carboxylase 2
Description: Contributes to methylcrotonoyl-CoA carboxylase activity. Involved in coenzyme A metabolic process. Predicted to localize to the methylcrotonoyl-CoA carboxylase complex and mitochondrial matrix. Human ortholog(s) of this gene implicated in 3-Methylcrotonyl-CoA carboxylase 2 deficiency and mitochondrial metabolism disease. Orthologous to human MCCC2 (methylcrotonoyl-CoA carboxylase 2); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; LOC361884; MCCase subunit beta; methylcrotonoyl-CoA carboxylase 2 (beta); methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
Orthologs:
Homo sapiens (human) : MCCC2 (methylcrotonoyl-CoA carboxylase 2)  HGNC  Alliance
Mus musculus (house mouse) : Mccc2 (methylcrotonoyl-Coenzyme A carboxylase 2 (beta))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mccc2 (methylcrotonoyl-CoA carboxylase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MCCC2 (methylcrotonoyl-CoA carboxylase 2)
Canis lupus familiaris (dog) : MCCC2 (methylcrotonoyl-CoA carboxylase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mccc2 (methylcrotonoyl-CoA carboxylase 2)
Sus scrofa (pig) : MCCC2 (methylcrotonoyl-CoA carboxylase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0230,175,017 - 30,246,028 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl230,175,018 - 30,246,010 (-)Ensembl
Rnor_5.0249,333,901 - 49,404,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4230,961,607 - 31,032,883 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1230,881,976 - 30,953,252 (-)NCBI
Celera227,327,945 - 27,397,754 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mccc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310279
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.