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Gene: Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6) Rattus norvegicus
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Symbol: Arhgef6
Name: Rac/Cdc42 guanine nucleotide exchange factor 6
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in lamellipodium assembly. Predicted to localize to the cell-cell junction and lamellipodium. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability. Orthologous to human ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6); PARTICIPATES IN ceramide signaling pathway; pancreatic cancer pathway; INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; rho guanine nucleotide exchange factor 6
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X159,722,031 - 159,841,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX159,723,866 - 159,841,072 (-)Ensembl
Rnor_5.0X154,351,133 - 154,467,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X141,946,362 - 142,068,557 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X142,019,794 - 142,141,990 (-)NCBI
CeleraX143,180,944 - 143,297,823 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359674
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.