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Gene: Kdsr (3-ketodihydrosphingosine reductase) Rattus norvegicus
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Symbol: Kdsr
Name: 3-ketodihydrosphingosine reductase
Description: Predicted to have 3-dehydrosphinganine reductase activity. Predicted to be involved in 3-keto-sphinganine metabolic process and sphingolipid biosynthetic process. Predicted to localize to the endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Orthologous to human KDSR (3-ketodihydrosphingosine reductase); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: follicular lymphoma variant translocation 1; Fvt1; LOC360833
Orthologs:
Homo sapiens (human) : KDSR (3-ketodihydrosphingosine reductase)  HGNC  Alliance
Mus musculus (house mouse) : Kdsr (3-ketodihydrosphingosine reductase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdsr (3-ketodihydrosphingosine reductase)
Pan paniscus (bonobo/pygmy chimpanzee) : KDSR (3-ketodihydrosphingosine reductase)
Canis lupus familiaris (dog) : KDSR (3-ketodihydrosphingosine reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdsr (3-ketodihydrosphingosine reductase)
Sus scrofa (pig) : KDSR (3-ketodihydrosphingosine reductase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01326,779,386 - 26,812,271 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,780,633 - 26,812,215 (-)Ensembl
Rnor_5.01331,929,862 - 31,962,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,914,967 - 12,946,853 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11312,914,896 - 12,946,797 (-)NCBI
Celera1322,721,005 - 22,752,490 (-)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kdsr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307775
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.