Gene: Clic2 (chloride intracellular channel 2) Rattus norvegicus
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Symbol: Clic2
Name: chloride intracellular channel 2
Description: ENCODES a protein that exhibits glutathione peroxidase activity (ortholog); INVOLVED IN negative regulation of ryanodine-sensitive calcium-release channel activity (ortholog); positive regulation of binding (ortholog); regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH autistic disorder (ortholog); Early Onset Parkinsonism with Mental Retardation (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 3,7-dihydropurine-6-thione; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: chloride intracellular channel protein 2; LOC294141; MGC108828
Orthologs:
Homo sapiens (human) : CLIC2 (chloride intracellular channel 2)  HGNC  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clic2 (chloride intracellular channel 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLIC2 (chloride intracellular channel 2)
Canis lupus familiaris (dog) : CLIC2 (chloride intracellular channel 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clic2 (chloride intracellular channel 2)
Sus scrofa (pig) : CLIC2 (chloride intracellular channel 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.020295,338 - 310,363 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.020289,420 - 304,445 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42066,518 - 81,543 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12066,517 - 81,536 (+)NCBI
Celera201,021,508 - 1,036,650 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Clic2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306580
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE