Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ICAM4 mRNA | CTD | PMID:23649840 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of ICAM4 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ICAM4 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ICAM4 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Icam4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ICAM4 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ICAM4 mRNA | CTD | PMID:21632981 | aflatoxin B1 | affects expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ICAM4 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ICAM4 mRNA | CTD | PMID:21632981 and PMID:21641981 | all-trans-retinoic acid | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ICAM4 mRNA | CTD | PMID:33167477 | aripiprazole | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [Aripiprazole co-treated with Ozone] results in increased expression of ICAM4 mRNA | CTD | PMID:31476115 | benzo[a]pyrene | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ICAM4 mRNA | CTD | PMID:20106945 more ... | benzo[a]pyrene | affects methylation | ISO | ICAM4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ICAM4 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Icam4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ICAM4 mRNA | CTD | PMID:17942131 | benzo[a]pyrene diol epoxide I | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ICAM4 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ICAM4 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ICAM4 mRNA | CTD | PMID:34947998 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ICAM4 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ICAM4 mRNA | CTD | PMID:29275510 | butanal | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ICAM4 mRNA | CTD | PMID:26079696 | cyclosporin A | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ICAM4 mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ICAM4 mRNA | CTD | PMID:21632981 and PMID:25562108 | cyclosporin A | decreases expression | ISO | Icam4 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of ICAM4 mRNA | CTD | PMID:17942131 | dextran sulfate | multiple interactions | ISO | Icam4 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ICAM4 mRNA | CTD | PMID:29950665 | dicrotophos | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of ICAM4 mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ICAM4 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ICAM4 mRNA | CTD | PMID:29803840 | entinostat | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ICAM4 mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | entinostat results in increased expression of ICAM4 mRNA | CTD | PMID:26272509 and PMID:27188386 | formaldehyde | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of ICAM4 mRNA | CTD | PMID:23649840 | fulvestrant | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ICAM4 gene | CTD | PMID:31601247 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ICAM4 mRNA | CTD | PMID:33387578 | hydrogen peroxide | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ICAM4 protein | CTD | PMID:18951874 | lipopolysaccharide | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of ICAM4 mRNA | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of ICAM4 mRNA | CTD | PMID:35811015 | ozone | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [Aripiprazole co-treated with Ozone] results in increased expression of ICAM4 mRNA | CTD | PMID:31476115 | ozone | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Ozone results in increased expression of ICAM4 mRNA | CTD | PMID:31476115 | paracetamol | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ICAM4 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ICAM4 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | Icam4 (Mus musculus) | 6480464 | Acetaminophen results in decreased expression of ICAM4 mRNA | CTD | PMID:17942131 | perfluorohexanesulfonic acid | increases expression | ISO | Icam4 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of ICAM4 mRNA | CTD | PMID:37995155 | propanal | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of ICAM4 mRNA | CTD | PMID:26079696 | quercetin | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ICAM4 mRNA | CTD | PMID:21632981 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of ICAM4 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ICAM4 mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of ICAM4 mRNA | CTD | PMID:23806026 | sunitinib | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ICAM4 mRNA | CTD | PMID:31533062 | theophylline | multiple interactions | ISO | ICAM4 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of ICAM4 protein | CTD | PMID:18951874 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ICAM4 mRNA | CTD | PMID:34492290 | titanium dioxide | multiple interactions | ISO | Icam4 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ICAM4 mRNA | CTD | PMID:29950665 | tremolite asbestos | decreases expression | ISO | Icam4 (Mus musculus) | 6480464 | tremolite results in decreased expression of ICAM4 mRNA | CTD | PMID:29279043 | Tributyltin oxide | increases expression | ISO | Icam4 (Mus musculus) | 6480464 | bis(tri-n-butyltin)oxide results in increased expression of ICAM4 mRNA | CTD | PMID:18958704 | Tributyltin oxide | decreases expression | ISO | Icam4 (Mus musculus) | 6480464 | bis(tri-n-butyltin)oxide results in decreased expression of ICAM4 mRNA | CTD | PMID:17942131 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ICAM4 mRNA | CTD | PMID:33387578 | triclosan | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of ICAM4 mRNA | CTD | PMID:30510588 | trovafloxacin | decreases expression | ISO | Icam4 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of ICAM4 mRNA | CTD | PMID:35537566 | valproic acid | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ICAM4 mRNA | CTD | PMID:24383497 and PMID:28001369 | valproic acid | increases methylation | ISO | ICAM4 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ICAM4 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ICAM4 mRNA | CTD | PMID:25979313 | vanadium atom | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Vanadium results in decreased expression of ICAM4 mRNA | CTD | PMID:19000753 | vanadium(0) | decreases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Vanadium results in decreased expression of ICAM4 mRNA | CTD | PMID:19000753 | vincristine | increases expression | ISO | ICAM4 (Homo sapiens) | 6480464 | Vincristine results in increased expression of ICAM4 mRNA | CTD | PMID:23649840 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