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Gene: Gfi1 (growth factor independent 1 transcriptional repressor) Rattus norvegicus
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Symbol: Gfi1
Name: growth factor independent 1 transcriptional repressor
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription regulatory region DNA binding activity. Predicted to be involved in several processes, including inner ear development; regulation of cell fate specification; and regulation of transcription, DNA-templated. Predicted to localize to the nuclear body; nuclear matrix; and transcriptional repressor complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia and severe congenital neutropenia. Orthologous to human GFI1 (growth factor independent 1 transcriptional repressor); INTERACTS WITH 1-naphthyl isothiocyanate; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: growth factor independent 1; growth factor independent 1 transcription repressor; growth factor independent protein 1; Growth factor independent-1; zinc finger protein Gfi-1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0143,058,035 - 3,073,332 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,058,993 - 3,068,371 (+)Ensembl
Rnor_5.0143,060,287 - 3,069,973 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,597,303 - 2,606,681 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,597,302 - 2,606,681 (+)NCBI
Celera142,061,330 - 2,070,708 (+)NCBICelera
Cytogenetic Map14p22NCBI
RH 3.4 Map1437.2RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gfi1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2680
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.