17alpha-ethynylestradiol multiple interactions ISO RGD:1552280 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NEFL mRNA CTD PMID:17942748 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1552280 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1552280 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1552280 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NEFL mRNA CTD PMID:17942748 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:1552280 6480464 2 more ... CTD PMID:18550172 2,5-hexanedione decreases expression EXP 6480464 2, 5-hexanedione results in decreased expression of NEFL protein CTD PMID:19033394 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein], Verapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 , PMID:21879721 2-methylcholine affects expression ISO RGD:1344238 6480464 beta-methylcholine affects the expression of NEFL mRNA CTD PMID:21179406 3,3',5-triiodo-L-thyronine decreases expression ISO RGD:1552280 6480464 Triiodothyronine results in decreased expression of NEFL mRNA CTD PMID:25172293 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of NEFL protein CTD PMID:26068050 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1344238 6480464 [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA CTD PMID:29698629 3-methyladenine multiple interactions ISO RGD:1344238 6480464 3-methyladenine inhibits the reaction [tri-o-cresyl phosphate results in decreased expression of NEFL protein] CTD PMID:23743148 5-azacytidine increases expression ISO RGD:1344238 6480464 Azacitidine results in increased expression of NEFL mRNA CTD PMID:20823114 6-Cyano-7-nitroquinoxaline-2,3-dione multiple interactions EXP 6480464 6-Cyano-7-nitroquinoxaline-2, 3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein] CTD PMID:21863293 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of NEFL mRNA CTD PMID:24780913 9-cis-retinoic acid decreases expression ISO RGD:1344238 6480464 Alitretinoin results in decreased expression of NEFL mRNA CTD PMID:15982314 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of NEFL mRNA, Acrylamide results in increased expression of NEFL protein CTD PMID:10678756 acrylamide multiple interactions EXP 6480464 NGF protein promotes the reaction [Acrylamide results in increased expression of NEFL protein] CTD PMID:10678756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of NEFL mRNA CTD PMID:23630614 aldrin increases expression ISO RGD:1552280 6480464 Aldrin results in increased expression of NEFL mRNA CTD PMID:18579281 all-trans-4-oxoretinoic acid decreases expression ISO RGD:1344238 6480464 4-oxoretinoic acid results in decreased expression of NEFL mRNA CTD PMID:15982314 all-trans-retinoic acid decreases expression ISO RGD:1344238 6480464 Tretinoin metabolite results in decreased expression of NEFL mRNA, Tretinoin results in decreased expression of NEFL mRNA CTD PMID:15982314 all-trans-retinoic acid increases expression ISO RGD:1344238 6480464 Tretinoin results in increased expression of NEFL mRNA, Tretinoin results in increased expression of NEFL protein CTD PMID:21934132 , PMID:26498558 all-trans-retinoic acid multiple interactions ISO RGD:1344238 6480464 [Tretinoin co-treated with SHH protein co-treated with FGF8 protein] results in increased expression of NEFL protein CTD PMID:17085092 aluminium sulfate (anhydrous) decreases expression ISO RGD:1344238 6480464 aluminum sulfate results in decreased expression of NEFL mRNA CTD PMID:15961160 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of NEFL mRNA CTD PMID:16483693 arsane affects expression ISO RGD:1344238 6480464 Arsenic metabolite affects the expression of NEFL mRNA CTD PMID:17553662 arsenic atom affects expression ISO RGD:1344238 6480464 Arsenic metabolite affects the expression of NEFL mRNA CTD PMID:17553662 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of NEFL protein CTD PMID:18242949 arsenite(3-) increases methylation ISO RGD:1344238 6480464 arsenite results in increased methylation of NEFL promoter CTD PMID:23974009 atrazine increases expression ISO RGD:1344238 6480464 Atrazine results in increased expression of NEFL mRNA CTD PMID:22378314 belinostat increases expression ISO RGD:1344238 6480464 belinostat results in increased expression of NEFL mRNA CTD PMID:26272509 benzo[a]pyrene multiple interactions ISO RGD:1552280 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to NEFL promoter] CTD PMID:19654925 benzo[a]pyrene increases expression ISO RGD:1344238 6480464 Benzo(a)pyrene results in increased expression of NEFL mRNA CTD PMID:22316170 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA CTD PMID:31199487 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of NEFL mRNA CTD PMID:25181051 Brodifacoum decreases expression EXP 6480464 bromfenacoum results in decreased expression of NEFL protein CTD PMID:28903499 bucladesine multiple interactions ISO RGD:1344238 6480464 [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA CTD PMID:29698629 butanal increases expression ISO RGD:1344238 6480464 butyraldehyde results in increased expression of NEFL mRNA CTD PMID:26079696 Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA CTD PMID:31199487 calcitriol decreases expression ISO RGD:1344238 6480464 Calcitriol results in decreased expression of NEFL mRNA CTD PMID:16002434 calcium atom multiple interactions EXP 6480464 Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] more ... CTD PMID:11071371 , PMID:21879721 calcium(0) multiple interactions EXP 6480464 Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] more ... CTD PMID:11071371 , PMID:21879721 Calpeptin multiple interactions EXP 6480464 calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein] CTD PMID:11071371 calyculin a multiple interactions EXP 6480464 calyculin A inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein] CTD PMID:21863293 carbon disulfide decreases expression EXP 6480464 Carbon Disulfide results in decreased expression of NEFL protein CTD PMID:16474999 , PMID:17120161 carbon disulfide increases expression EXP 6480464 Carbon Disulfide results in increased expression of NEFL mRNA, Carbon Disulfide results in increased expression of NEFL protein CTD PMID:17120161 , PMID:19165470 chloroethene increases expression ISO RGD:1552280 6480464 Vinyl Chloride results in increased expression of NEFL mRNA CTD PMID:18579281 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of NEFL mRNA CTD PMID:18812211 chlorpyrifos increases expression ISO RGD:1552280 6480464 Chlorpyrifos results in increased expression of NEFL mRNA CTD PMID:26018426 choline multiple interactions ISO RGD:1552280 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NEFL gene CTD PMID:20938992 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of NEFL mRNA CTD PMID:22023808 cisplatin increases expression ISO RGD:1344238 6480464 Cisplatin results in increased expression of NEFL mRNA CTD PMID:27392435 cisplatin multiple interactions ISO RGD:1344238 6480464 Cisplatin promotes the reaction [jinfukang results in increased expression of NEFL mRNA], jinfukang promotes the reaction [Cisplatin results in increased expression of NEFL mRNA] CTD PMID:27392435 cobalt dichloride increases expression ISO RGD:1344238 6480464 cobaltous chloride results in increased expression of NEFL mRNA CTD PMID:19376846 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of NEFL mRNA CTD PMID:18375950 cocaine affects expression EXP 6480464 Cocaine affects the expression of NEFL mRNA CTD PMID:20187946 cocaine decreases expression ISO RGD:1344238 6480464 Cocaine results in decreased expression of NEFL mRNA CTD PMID:12629581 cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of NEFL mRNA CTD PMID:16076954 copper atom multiple interactions ISO RGD:1344238 6480464 [NSC 689534 binds to Copper] which results in decreased expression of NEFL mRNA CTD PMID:20971185 copper atom multiple interactions ISO RGD:1552280 6480464 MT1 affects the reaction [Copper results in increased expression of NEFL mRNA], MT2 affects the reaction [Copper results in increased expression of NEFL mRNA] CTD PMID:16629173 copper(0) multiple interactions ISO RGD:1344238 6480464 [NSC 689534 binds to Copper] which results in decreased expression of NEFL mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1552280 6480464 MT1 affects the reaction [Copper results in increased expression of NEFL mRNA], MT2 affects the reaction [Copper results in increased expression of NEFL mRNA] CTD PMID:16629173 copper(II) chloride decreases expression ISO RGD:1552280 6480464 cupric chloride results in decreased expression of NEFL protein CTD PMID:29617964 cycloheximide decreases expression EXP 6480464 Cycloheximide results in decreased expression of NEFL mRNA CTD PMID:19146868 daidzein 7-O-beta-D-glucoside increases expression EXP 6480464 daidzin results in increased expression of NEFL mRNA, daidzin results in increased expression of NEFL protein CTD PMID:31034797 dantrolene multiple interactions EXP 6480464 Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein], Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 , PMID:21879721 dexamethasone increases expression ISO RGD:1344238 6480464 Dexamethasone results in increased expression of NEFL mRNA CTD PMID:25047013 dibutyl phthalate decreases expression ISO RGD:1552280 6480464 Dibutyl Phthalate results in decreased expression of NEFL mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA CTD PMID:31199487 dichlorvos decreases expression EXP 6480464 Dichlorvos results in decreased expression of NEFL mRNA CTD PMID:19146868 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of NEFL mRNA CTD PMID:18812211 diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA CTD PMID:31199487 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of NEFL mRNA CTD PMID:17005392 diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA CTD PMID:31199487 diisononyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA CTD PMID:31199487 diuron decreases expression EXP 6480464 Diuron results in decreased expression of NEFL mRNA CTD PMID:25152437 diuron increases expression EXP 6480464 Diuron results in increased expression of NEFL mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:1344238 6480464 Doxorubicin results in increased expression of NEFL mRNA CTD PMID:25529476 more ... endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of NEFL mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:1344238 6480464 entinostat results in increased expression of NEFL mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEFL mRNA CTD PMID:27188386 enzyme inhibitor multiple interactions ISO RGD:1344238 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NEFL protein CTD PMID:23301498 ethanol affects expression ISO RGD:1552280 6480464 Ethanol affects the expression of NEFL mRNA CTD PMID:15513904 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of NEFL protein CTD PMID:16770775 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 [1 more ... CTD PMID:21879721 folic acid multiple interactions ISO RGD:1552280 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NEFL gene CTD PMID:20938992 furan increases expression EXP 6480464 furan results in increased expression of NEFL mRNA CTD PMID:25539665 Heptachlor epoxide decreases expression ISO RGD:1552280 6480464 Heptachlor Epoxide results in decreased expression of NEFL mRNA CTD PMID:25270620 hydrogen sulfide decreases expression ISO RGD:1552280 6480464 Hydrogen Sulfide results in decreased expression of NEFL protein CTD PMID:29932956 indometacin multiple interactions EXP 6480464 Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] CTD PMID:11071371 isotretinoin decreases expression ISO RGD:1344238 6480464 Isotretinoin results in decreased expression of NEFL mRNA CTD PMID:15982314 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of NEFL protein CTD PMID:18504422 ketamine increases expression EXP 6480464 Ketamine results in increased expression of NEFL mRNA CTD PMID:20080153 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21879721 L-methionine multiple interactions ISO RGD:1552280 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NEFL gene CTD PMID:20938992 lead diacetate increases expression ISO RGD:1552280 6480464 lead acetate results in increased expression of NEFL protein CTD PMID:20797405 leupeptin multiple interactions ISO RGD:1344238 6480464 leupeptin inhibits the reaction [CTSB protein results in increased degradation of NEFL protein] CTD PMID:11071371 manganese atom increases expression ISO RGD:1552280 6480464 Manganese results in increased expression of NEFL protein CTD PMID:22191580 manganese atom multiple interactions ISO RGD:1552280 6480464 HTT protein mutant form inhibits the reaction [Manganese results in increased expression of NEFL protein] CTD PMID:22191580 manganese(0) increases expression ISO RGD:1552280 6480464 Manganese results in increased expression of NEFL protein CTD PMID:22191580 manganese(0) multiple interactions ISO RGD:1552280 6480464 HTT protein mutant form inhibits the reaction [Manganese results in increased expression of NEFL protein] CTD PMID:22191580 manganese(II) chloride decreases expression ISO RGD:1552280 6480464 manganese chloride results in decreased expression of NEFL mRNA CTD PMID:15295902 mercury dibromide increases expression ISO RGD:1344238 6480464 mercuric bromide results in increased expression of NEFL mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEFL mRNA CTD PMID:27188386 methylmercury chloride affects expression ISO RGD:1552280 6480464 methylmercuric chloride affects the expression of NEFL mRNA CTD PMID:21613230 methylmercury chloride increases expression ISO RGD:1344238 6480464 methylmercuric chloride results in increased expression of NEFL mRNA CTD PMID:23179753 , PMID:28001369 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of NEFL mRNA CTD PMID:19651682 nifedipine multiple interactions EXP 6480464 Nifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein] CTD PMID:21863293 ouabain decreases expression ISO RGD:1344238 6480464 Ouabain results in decreased expression of NEFL mRNA CTD PMID:28795476 panobinostat increases expression ISO RGD:1344238 6480464 panobinostat results in increased expression of NEFL mRNA CTD PMID:26272509 panobinostat multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEFL mRNA CTD PMID:27188386 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of NEFL mRNA, Paraquat results in decreased expression of NEFL protein CTD PMID:19146868 , PMID:24521700 parathion decreases expression EXP 6480464 Parathion results in decreased expression of NEFL mRNA CTD PMID:19146868 pentanal increases expression ISO RGD:1344238 6480464 pentanal results in increased expression of NEFL mRNA CTD PMID:26079696 phenylmercury acetate increases expression ISO RGD:1344238 6480464 Phenylmercuric Acetate results in increased expression of NEFL mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEFL mRNA CTD PMID:27188386 propanal increases expression ISO RGD:1344238 6480464 propionaldehyde results in increased expression of NEFL mRNA CTD PMID:26079696 raloxifene affects expression ISO RGD:1344238 6480464 Raloxifene Hydrochloride affects the expression of NEFL mRNA CTD PMID:14699072 SB 431542 multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sodium arsenite multiple interactions ISO RGD:1344238 6480464 [sodium arsenite affects the acetylation of H3-4 protein] which affects the methylation of NEFL promoter CTD PMID:18448484 sodium arsenite affects expression ISO RGD:1344238 6480464 sodium arsenite affects the expression of NEFL mRNA CTD PMID:29319823 sodium arsenite increases expression ISO RGD:1344238 6480464 sodium arsenite results in increased expression of NEFL mRNA CTD PMID:28595984 sodium arsenite multiple interactions EXP 6480464 sodium arsenite results in decreased expression of and results in increased phosphorylation of NEFL protein CTD PMID:18674524 sodium arsenite increases expression ISO RGD:1552280 6480464 sodium arsenite results in increased expression of NEFL mRNA CTD PMID:23022324 , PMID:28370166 sodium arsenite decreases expression ISO RGD:1344238 6480464 sodium arsenite results in decreased expression of NEFL mRNA CTD PMID:18448484 Soman increases expression EXP 6480464 Soman results in increased expression of NEFL mRNA CTD PMID:19281266 staurosporine multiple interactions EXP 6480464 Staurosporine inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21879721 terbutaline increases expression EXP 6480464 Terbutaline results in increased expression of NEFL protein CTD PMID:14610225 tetrachloroethene decreases expression EXP 6480464 Tetrachloroethylene results in decreased expression of NEFL protein CTD PMID:8372046 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of NEFL mRNA CTD PMID:23411599 Tributyltin oxide decreases expression ISO RGD:1552280 6480464 bis(tri-n-butyltin)oxide results in decreased expression of NEFL mRNA CTD PMID:25270620 trichostatin A increases expression ISO RGD:1344238 6480464 trichostatin A results in increased expression of NEFL mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEFL mRNA CTD PMID:27188386 triclosan decreases expression ISO RGD:1344238 6480464 Triclosan results in decreased expression of NEFL mRNA CTD PMID:30510588 U-73122 multiple interactions EXP 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:21879721 uranium atom affects expression ISO RGD:1344238 6480464 Uranium affects the expression of NEFL mRNA CTD PMID:15672453 valproic acid decreases expression ISO RGD:1552280 6480464 Valproic Acid results in decreased expression of NEFL mRNA CTD PMID:21427059 valproic acid multiple interactions ISO RGD:1344238 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEFL mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1344238 6480464 Valproic Acid results in increased expression of NEFL mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:1552280 6480464 Valproic Acid affects the expression of NEFL mRNA CTD PMID:17292431 , PMID:26072468 valproic acid affects expression ISO RGD:1344238 6480464 Valproic Acid affects the expression of NEFL mRNA CTD PMID:25979313 , PMID:26072468 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of NEFL mRNA CTD PMID:19651682 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein], Verapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 , PMID:21879721 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of NEFL mRNA CTD PMID:20566332 vorinostat increases expression ISO RGD:1344238 6480464 vorinostat results in increased expression of NEFL mRNA CTD PMID:26272509 Z-Val-Phe-H multiple interactions EXP 6480464 calpain inhibitor III inhibits the reaction [Zymosan results in increased degradation of NEFL protein] CTD PMID:15275793 zoledronic acid decreases expression ISO RGD:1344238 6480464 zoledronic acid results in decreased expression of NEFL mRNA CTD PMID:24714768
Biological Process anterograde axonal transport ISO RGD:1344238 1624291 (PMID:15857389) RGD PMID:15857389 anterograde axonal transport IEA UniProtKB:P07196 , ensembl:ENSP000004821691600115 GO_REF:0000107 Ensembl GO_REF:0000107 axonal transport of mitochondrion ISO RGD:1344238 1624291 (PMID:15857389) RGD PMID:15857389 axonal transport of mitochondrion IEA UniProtKB:P07196 , ensembl:ENSP000004821691600115 GO_REF:0000107 Ensembl GO_REF:0000107 cerebral cortex development IEP 9743942 RGD hippocampus development IEP 9743946 RGD intermediate filament bundle assembly ISO RGD:1552280 1624291 MGI:MGI:97309 more ... RGD MGI:MGI:1342909 more ... intermediate filament organization ISO RGD:1552280 1624291 (MGI:MGI:1096547 more ... RGD MGI:MGI:1096547 more ... intermediate filament organization ISO RGD:1344238 1624291 (PMID:12432080), (PMID:17052987) RGD PMID:12432080 , PMID:17052987 intermediate filament polymerization or depolymerization IDA 9698446 RGD locomotion ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:1347434 , PMID:15132161) RGD MGI:MGI:1347434 , PMID:15132161 locomotion IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 microtubule cytoskeleton organization ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:2148377 , PMID:11487626) RGD MGI:MGI:2148377 , PMID:11487626 microtubule cytoskeleton organization IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of neuron apoptotic process ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:1096547 more ... RGD MGI:MGI:1096547 more ... negative regulation of neuron apoptotic process IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 neurofilament bundle assembly IDA 9743935 RGD neurofilament bundle assembly ISO RGD:1344238 1624291 (PMID:12432080), (PMID:15857389) RGD PMID:12432080 , PMID:15857389 neurofilament cytoskeleton organization ISO RGD:1552280 1624291 MGI:MGI:2180095 more ... RGD MGI:MGI:1100197 more ... neurofilament cytoskeleton organization IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 neuromuscular process controlling balance ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:3614333 , PMID:15884021) RGD MGI:MGI:3614333 , PMID:15884021 neuromuscular process controlling balance IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 neuron projection morphogenesis ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:1861055 , PMID:10884316) RGD MGI:MGI:1861055 , PMID:10884316 neuron projection morphogenesis IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 peripheral nervous system axon regeneration ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:1100197 , PMID:9398473) RGD MGI:MGI:1100197 , PMID:9398473 peripheral nervous system axon regeneration IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of axonogenesis ISO RGD:1552280 1624291 (MGI:MGI:1096547, PMID:7946341) RGD MGI:MGI:1096547 , PMID:7946341 positive regulation of axonogenesis IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 postsynaptic intermediate filament cytoskeleton organization IEA GO:0099184 1600115 GO_REF:0000108 GOC GO_REF:0000108 protein polymerization IDA 2299004 RGD regulation of axon diameter ISO RGD:1552280 1624291 MGI:MGI:2180095 (MGI:MGI:1100197 more ... RGD MGI:MGI:1100197 more ... regulation of axon diameter IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to acrylamide IEP 2299006 RGD response to corticosterone IEP 2299003 RGD response to organic substance IEP 2299000 RGD response to peptide hormone IEP 2299001 RGD response to sodium arsenite IDA 9693729 RGD response to toxic substance IEP 2299002 RGD retrograde axonal transport ISO RGD:1344238 1624291 (PMID:15857389) RGD PMID:15857389 retrograde axonal transport IEA UniProtKB:P07196 , ensembl:ENSP000004821691600115 GO_REF:0000107 Ensembl GO_REF:0000107 spinal cord development IEP 9698442 RGD synapse maturation IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 synapse maturation ISO RGD:1552280 1624291 (MGI:MGI:5609100, PMID:25232125) RGD MGI:MGI:5609100 , PMID:25232125 Cellular Component axon IDA 2299008 RGD axon ISO RGD:1552280 1624291 (MGI:MGI:2180126 more ... RGD MGI:MGI:2180126 more ... axon ISO RGD:1344238 1624291 (PMID:14662745) RGD PMID:14662745 axon cytoplasm IEA GO:0008090 1600115 GO_REF:0000108 GOC GO_REF:0000108 axon cytoplasm IEA GO:0019896 1600115 GO_REF:0000108 GOC GO_REF:0000108 cholinergic synapse IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 cholinergic synapse ISO RGD:1552280 1624291 (MGI:MGI:5609100, PMID:25232125) RGD MGI:MGI:5609100 , PMID:25232125 cytoplasm ISO RGD:1552280 1624291 (MGI:MGI:5553249, PMID:11034913) RGD MGI:MGI:5553249 , PMID:11034913 growth cone IDA 633519 RGD intermediate filament ISO RGD:1552280 1624291 (MGI:MGI:5553249 more ... RGD MGI:MGI:5553249 more ... neurofilament IDA 9743935 RGD neurofilament ISO RGD:14285052 1624291 (PMID:3920075), (PMID:8634266) RGD PMID:3920075 , PMID:8634266 neurofilament ISO RGD:1344238 1624291 (PMID:15857389) RGD PMID:15857389 neurofilament ISO RGD:1552280 1624291 (MGI:MGI:1336062 more ... RGD MGI:MGI:1336062 more ... neuromuscular junction IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 neuromuscular junction ISO RGD:1552280 1624291 (MGI:MGI:5609100, PMID:25232125) RGD MGI:MGI:5609100 , PMID:25232125 neuron projection IDA 633519 RGD neuron projection ISO RGD:1552280 1624291 (MGI:MGI:2158988 more ... RGD MGI:MGI:2158988 more ... neuron projection colocalizes_with IDA 1599284 RGD postsynaptic intermediate filament cytoskeleton IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 postsynaptic intermediate filament cytoskeleton ISO RGD:1552280 1624291 (MGI:MGI:6189617, PMID:25869803) RGD MGI:MGI:6189617 , PMID:25869803 presynaptic intermediate filament cytoskeleton IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 presynaptic intermediate filament cytoskeleton ISO RGD:1552280 1624291 (MGI:MGI:5609100, PMID:25232125) RGD MGI:MGI:5609100 , PMID:25232125 Schaffer collateral - CA1 synapse IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 Schaffer collateral - CA1 synapse ISO RGD:1552280 1624291 (MGI:MGI:6189617, PMID:25869803) RGD MGI:MGI:6189617 , PMID:25869803 Molecular Function identical protein binding ISO RGD:1344238 1624291 UniProtKB:P07196 (PMID:12432080) RGD PMID:12432080 identical protein binding IEA UniProtKB:P07196 , ensembl:ENSP000004821691600115 GO_REF:0000107 Ensembl GO_REF:0000107 phospholipase binding IPI RGD:3347 1599284 RGD protein binding ISO RGD:1552280 1624291 UniProtKB:P97433 more ... RGD MGI:MGI:2429348 more ... protein binding ISO RGD:1344238 1624291 UniProtKB:P05067 more ... RGD PMID:12837694 more ... protein binding, bridging ISO RGD:1552280 1624291 (MGI:MGI:5553249, PMID:11034913) RGD MGI:MGI:5553249 , PMID:11034913 protein binding, bridging IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein C-terminus binding ISO RGD:1344238 1624291 UniProtKB:Q92574 (PMID:12226091) RGD PMID:12226091 protein C-terminus binding IEA UniProtKB:P07196 , ensembl:ENSP000004821691600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein domain specific binding IPI RGD:3347 1599284 RGD protein-containing complex binding IDA 9743943 heterodimerization RGD structural constituent of cytoskeleton ISO RGD:1344238 1624291 (PMID:12432080) RGD PMID:12432080 structural constituent of cytoskeleton ISO RGD:1552280 1624291 (MGI:MGI:5553249, PMID:11034913) RGD MGI:MGI:5553249 , PMID:11034913 structural constituent of postsynaptic intermediate filament cytoskeleton IEA UniProtKB:P08551 , ensembl:ENSMUSP000000226391600115 GO_REF:0000107 Ensembl GO_REF:0000107 structural constituent of postsynaptic intermediate filament cytoskeleton ISO RGD:1552280 1624291 (MGI:MGI:6189617, PMID:25869803) RGD MGI:MGI:6189617 , PMID:25869803
Gene-Chemical Interaction Annotations
