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ONTOLOGY REPORT - ANNOTATIONS


Term:ajmalicine
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Accession:CHEBI:2524 term browser browse the term
Definition:A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure.
Synonyms:exact_synonym: methyl (19alpha)-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate
 related_synonym: (19alpha)-16,17-didehydro-19-methyl-oxayohimban-16-carboxylic acid methyl ester;   Circolene;   Cristanyl;   Duxil;   Formula=C21H24N2O3;   InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16+,19-/m0/s1;   InChIKey=GRTOGORTSDXSFK-XJTZBENFSA-N;   Lamuran;   Raubasine;   SMILES=C=1C=CC=2NC=3[C@]4(N(CCC3C2C1)C[C@]5([C@@](C(=CO[C@H]5C)C(OC)=O)(C4)[H])[H])[H];   Sarpan;   ajmalicin;   delta-yohimbine;   methyl (4S,4aR,13bS,14aS)-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate
 xref: CAS:483-04-5 "ChemIDplus";   CAS:483-04-5 "KEGG COMPOUND";   CAS:483-04-5 "NIST Chemistry WebBook";   KEGG:C09024;   KEGG:D08470;   KNApSAcK:C00001678;   LINCS:LSM-15373
 xref_mesh: MESH:C005709
 xref: PMID:15930738 "Europe PMC";   PMID:19151732 "Europe PMC";   PMID:22331368 "Europe PMC";   PMID:22332772 "Europe PMC";   PMID:24237015 "Europe PMC";   PMID:26983347 "Europe PMC";   PMID:27584856 "Europe PMC";   PMID:4387608 "Europe PMC";   PMID:6091834 "Europe PMC";   PMID:6128043 "Europe PMC";   Reaxys:97268 "Reaxys";   Wikipedia:Ajmalicine
 cyclic_relationship: is_conjugate_base_of CHEBI:142527


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ajmalicine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        fuel 10292
          methanol 2946
            methyl ester 2937
              ajmalicine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      chalcogen 19217
                        oxygen atom 19171
                          oxygen molecular entity 19171
                            hydroxides 18951
                              organic hydroxy compound 18493
                                alcohol 14911
                                  aliphatic alcohol 11047
                                    alkyl alcohol 11000
                                      methanol 2946
                                        methyl ester 2937
                                          ajmalicine 1
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