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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62388
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Htr5b
Name: 5-hydroxytryptamine (serotonin) receptor 5B
Acc ID: CHEBI:584020
Term: methysergide
Definition: A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.
Chemical ID: MESH:D008784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Htr5bmultiple interactionsEXP 2303647RGDmethysergide binds to protein 5-Htr5b; inhibits the reaction[5-carboxamidotryptamine binds to 5-Htr5b] 
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