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Gene: Tnni3 (troponin I3, cardiac type) Rattus norvegicus
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Symbol: Tnni3
Name: troponin I3, cardiac type
Description: Predicted to have several functions, including calcium channel inhibitor activity; calcium-dependent protein binding activity; and cytoskeletal protein binding activity. Involved in cardiac muscle contraction and regulation of smooth muscle contraction. Localizes to the sarcomere. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNI3 (troponin I3, cardiac type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (R)-lipoic acid; (S)-colchicine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cardiac troponin I; cTNI; TnI; troponin 1, type 3; Troponin I; troponin I cardiac; troponin I type 3 (cardiac); troponin I, cardiac; troponin I, cardiac muscle
Orthologs:
Homo sapiens (human) : TNNI3 (troponin I3, cardiac type)  HGNC  Alliance
Mus musculus (house mouse) : Tnni3 (troponin I, cardiac 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnni3 (troponin I3, cardiac type)
Pan paniscus (bonobo/pygmy chimpanzee) : TNNI3 (troponin I3, cardiac type)
Canis lupus familiaris (dog) : TNNI3 (troponin I3, cardiac type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnni3 (troponin I3, cardiac type)
Sus scrofa (pig) : TNNI3 (troponin I3, cardiac type)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0172,882,806 - 72,886,490 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,882,806 - 72,886,488 (+)Ensembl
Rnor_5.0175,665,119 - 75,668,803 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4168,028,198 - 68,031,882 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1168,106,308 - 68,109,991 (+)NCBI
Celera167,824,338 - 67,828,022 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tnni3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62052
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.