Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62052
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnni3
Name: troponin I3, cardiac type
Acc ID: CHEBI:78543
Term: ponatinib
Definition: A benzamide obtained by the formal condensation of the carboxy group of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid with the anilino group of 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline.
Chemical ID: MESH:C545373
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnni3increases secretionISORGD:7372046480464CTDponatinib results in increased secretion of TNNI3 protein

PMID:25304212
Go Back to source page   Continue to Ontology report