Gene: Mbd4 (methyl-CpG binding domain 4 DNA glycosylase) Rattus norvegicus
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Symbol: Mbd4
Name: methyl-CpG binding domain 4 DNA glycosylase
Description: ENCODES a protein that exhibits DNA binding (ortholog); pyrimidine-specific mismatch base pair DNA N-glycosylase activity (ortholog); INVOLVED IN response to estradiol; cellular response to DNA damage stimulus (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); PARTICIPATES IN altered DNA modification pathway; DNA modification pathway; base excision repair pathway; ASSOCIATED WITH autistic disorder (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nuclear speck (ortholog); INTERACTS WITH decabromodiphenyl ether; quercetin; (-)-demecolcine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC680915; methyl-CpG binding domain protein 4; methyl-CpG-binding domain protein 4; similar to Methyl-CpG-binding domain protein 4 (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase)
Orthologs:
Homo sapiens (human) : MBD4 (methyl-CpG binding domain 4, DNA glycosylase)  HGNC  Alliance
Mus musculus (house mouse) : Mbd4 (methyl-CpG binding domain protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbd4 (methyl-CpG binding domain 4, DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MBD4 (methyl-CpG binding domain 4, DNA glycosylase)
Canis lupus familiaris (dog) : MBD4 (methyl-CpG binding domain 4, DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mbd4 (methyl-CpG binding domain 4, DNA glycosylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04147,744,673 - 147,756,462 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04211,028,384 - 211,040,158 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44151,972,272 - 151,981,633 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4137,783,059 - 137,794,850 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mbd4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585874
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE