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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | RGD:733933 | 6480464 | Demecolcine results in increased expression of CLASP2 mRNA | CTD | PMID:23649840 | 1,2-dichloroethane | decreases expression | ISO | RGD:736878 | 6480464 | ethylene dichloride results in decreased expression of CLASP2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:736878 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of CLASP2 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | RGD:733933 | 6480464 | Estradiol affects the expression of CLASP2 mRNA | CTD | PMID:14699072 | 17beta-estradiol | multiple interactions | ISO | RGD:733933 | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of CLASP2 mRNA | CTD | PMID:20404318 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | RGD:736878 | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CLASP2 mRNA | CTD | PMID:33387578 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of CLASP2 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of CLASP2 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:736878 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of CLASP2 mRNA | CTD | PMID:20188158 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:736878 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of CLASP2 mRNA | CTD | PMID:26251327 | aflatoxin B1 | decreases methylation | ISO | RGD:733933 | 6480464 | Aflatoxin B1 results in decreased methylation of CLASP2 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | RGD:733933 | 6480464 | Tretinoin results in increased expression of CLASP2 mRNA | CTD | PMID:23724009, PMID:33167477 | aristolochic acid A | decreases expression | ISO | RGD:733933 | 6480464 | aristolochic acid I results in decreased expression of CLASP2 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | RGD:733933 | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to CLASP2 mRNA] | CTD | PMID:32406909 | atrazine | increases expression | ISO | RGD:733933 | 6480464 | Atrazine results in increased expression of CLASP2 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | ISO | RGD:733933 | 6480464 | Benzo(a)pyrene results in decreased expression of CLASP2 mRNA | CTD | PMID:20064835 | benzo[a]pyrene | decreases methylation | ISO | RGD:736878 | 6480464 | Benzo(a)pyrene results in decreased methylation of CLASP2 exon, Benzo(a)pyrene results in decreased methylation of CLASP2 intron | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | RGD:733933 | 6480464 | Benzo(a)pyrene affects the methylation of CLASP2 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:733933 | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CLASP2 mRNA | CTD | PMID:25181051, PMID:30816183 | bisphenol A | decreases expression | ISO | RGD:736878 | 6480464 | bisphenol A results in decreased expression of CLASP2 mRNA | CTD | PMID:32156529 | caffeine | affects phosphorylation | ISO | RGD:733933 | 6480464 | Caffeine affects the phosphorylation of CLASP2 protein | CTD | PMID:35688186 | cerium trichloride | increases expression | ISO | RGD:736878 | 6480464 | cerous chloride results in increased expression of CLASP2 mRNA | CTD | PMID:23573234 | clobetasol | decreases expression | ISO | RGD:736878 | 6480464 | Clobetasol results in decreased expression of CLASP2 mRNA | CTD | PMID:27462272 | coumarin | affects phosphorylation | ISO | RGD:733933 | 6480464 | coumarin affects the phosphorylation of CLASP2 protein | CTD | PMID:35688186 | crocidolite asbestos | decreases expression | ISO | RGD:736878 | 6480464 | Asbestos, Crocidolite results in decreased expression of CLASP2 mRNA | CTD | PMID:29279043 | DDT | decreases methylation | EXP | | 6480464 | DDT results in decreased methylation of CLASP2 gene | CTD | PMID:30207508 | dibutyl phthalate | increases expression | ISO | RGD:736878 | 6480464 | Dibutyl Phthalate results in increased expression of CLASP2 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | RGD:733933 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:733933 | 6480464 | Doxorubicin results in decreased expression of CLASP2 mRNA | CTD | PMID:29803840 | entinostat | decreases expression | ISO | RGD:733933 | 6480464 | entinostat results in decreased expression of CLASP2 mRNA | CTD | PMID:27188386 | enzyme inhibitor | multiple interactions | ISO | RGD:733933 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CLASP2 protein | CTD | PMID:23301498 | ethanol | affects splicing | ISO | RGD:736878 | 6480464 | Ethanol affects the splicing of CLASP2 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | RGD:733933 | 6480464 | Ethyl Methanesulfonate results in decreased expression of CLASP2 mRNA | CTD | PMID:23649840 | formaldehyde | decreases expression | ISO | RGD:733933 | 6480464 | Formaldehyde results in decreased expression of CLASP2 mRNA | CTD | PMID:23649840 | hydralazine | multiple interactions | ISO | RGD:733933 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of CLASP2 mRNA | CTD | PMID:17183730 | ivermectin | decreases expression | ISO | RGD:733933 | 6480464 | Ivermectin results in decreased expression of CLASP2 protein | CTD | PMID:32959892 | lead(0) | affects expression | ISO | RGD:733933 | 6480464 | Lead affects the expression of CLASP2 mRNA | CTD | PMID:28903495 | lead(0) | affects splicing | ISO | RGD:733933 | 6480464 | Lead affects the splicing of CLASP2 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:733933 | 6480464 | Lead affects the expression of CLASP2 mRNA | CTD | PMID:28903495 | lead(2+) | affects splicing | ISO | RGD:733933 | 6480464 | Lead affects the splicing of CLASP2 mRNA | CTD | PMID:28903495 | mercury atom | increases expression | ISO | RGD:733933 | 6480464 | Mercury results in increased expression of CLASP2 mRNA | CTD | PMID:16823088 | mercury(0) | increases expression | ISO | RGD:733933 | 6480464 | Mercury results in increased expression of CLASP2 mRNA | CTD | PMID:16823088 | methyl methanesulfonate | decreases expression | ISO | RGD:733933 | 6480464 | Methyl Methanesulfonate results in decreased expression of CLASP2 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | RGD:733933 | 6480464 | methylmercuric chloride results in decreased expression of CLASP2 mRNA | CTD | PMID:28001369 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:736878 | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of CLASP2 mRNA | CTD | PMID:22401849 | ochratoxin A | multiple interactions | ISO | RGD:733933 | 6480464 | [ochratoxin A results in decreased acetylation of CLASP2 promoter] which results in decreased expression of CLASP2 mRNA | CTD | PMID:29098329 | ochratoxin A | decreases acetylation | ISO | RGD:733933 | 6480464 | ochratoxin A results in decreased acetylation of CLASP2 promoter | CTD | PMID:29098329 | ochratoxin A | decreases expression | ISO | RGD:733933 | 6480464 | ochratoxin A results in decreased expression of CLASP2 mRNA | CTD | PMID:29098329 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of CLASP2 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CLASP2 mRNA | CTD | PMID:33387578 | phenylmercury acetate | decreases expression | ISO | RGD:733933 | 6480464 | Phenylmercuric Acetate results in decreased expression of CLASP2 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:733933 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CLASP2 mRNA | CTD | PMID:27188386 | quercetin | decreases expression | ISO | RGD:733933 | 6480464 | Quercetin results in decreased expression of CLASP2 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | RGD:733933 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of CLASP2 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | RGD:733933 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sunitinib | increases expression | ISO | RGD:733933 | 6480464 | Sunitinib results in increased expression of CLASP2 mRNA | CTD | PMID:31533062 | thimerosal | increases expression | ISO | RGD:733933 | 6480464 | Thimerosal results in increased expression of CLASP2 mRNA | CTD | PMID:27188386 | toluene | decreases expression | EXP | | 6480464 | Toluene results in decreased expression of CLASP2 mRNA | CTD | PMID:22166486 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of CLASP2 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of CLASP2 mRNA | CTD | PMID:25729387 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of CLASP2 gene | CTD | PMID:27618143 | trichostatin A | increases expression | ISO | RGD:733933 | 6480464 | trichostatin A results in increased expression of CLASP2 mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:733933 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLASP2 mRNA | CTD | PMID:27188386 | triptonide | affects expression | ISO | RGD:736878 | 6480464 | triptonide affects the expression of CLASP2 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | ISO | RGD:736878 | 6480464 | troglitazone results in decreased expression of CLASP2 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | ISO | RGD:736878 | 6480464 | Tungsten results in decreased expression of CLASP2 mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | RGD:733933 | 6480464 | Valproic Acid results in increased methylation of CLASP2 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | RGD:733933 | 6480464 | Valproic Acid results in decreased expression of CLASP2 mRNA | CTD | PMID:23179753, PMID:27188386 | valproic acid | multiple interactions | ISO | RGD:733933 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of CLASP2 mRNA | CTD | PMID:17183730 | valproic acid | affects expression | ISO | RGD:733933 | 6480464 | Valproic Acid affects the expression of CLASP2 mRNA | CTD | PMID:25979313 | vincristine | increases expression | ISO | RGD:733933 | 6480464 | Vincristine results in increased expression of CLASP2 mRNA | CTD | PMID:23649840 | |