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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a23-3a1
Name: cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
Acc ID: CHEBI:28973
Term: strychnine
Definition: A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.
Chemical ID: MESH:D013331
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a23-3a1multiple interactionsEXP 6480464CTD[Strychnine co-treated with Ketoconazole] results in decreased expression of CYP3A23-3A1 protein; [Strychnine co-treated with Phenobarbital] results in increased expression of CYP3A23-3A1 mRNAPMID:35358606
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