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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3807
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tac1
Name: tachykinin, precursor 1
Acc ID: CHEBI:28487
Term: reserpine
Definition: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Chemical ID: MESH:D012110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tac1increases expressionEXP 6480464CTDReserpine results in increased expression of TAC1 mRNAPMID:17719177
Tac1multiple interactionsEXP 6480464CTD[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA; [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine] results in increased expression of TAC1 mRNA; Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA]PMID:17719177 PMID:9751140
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