Pm20d2 (peptidase M20 domain containing 2) - Rat Genome Database

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Gene: Pm20d2 (peptidase M20 domain containing 2) Rattus norvegicus
Analyze
Symbol: Pm20d2
Name: peptidase M20 domain containing 2
RGD ID: 1307853
Description: Enables dipeptidase activity. Acts upstream of or within proteolysis. Predicted to be located in nucleoplasm. Orthologous to human PM20D2 (peptidase M20 domain containing 2); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Acy1l2; aminoacylase 1-like 2; LOC313130; peptidase M20 domain-containing protein 2; xaa-Arg dipeptidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,362,384 - 52,382,647 (-)NCBIGRCr8
mRatBN7.2547,566,059 - 47,586,334 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,566,072 - 47,586,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,712,103 - 49,732,173 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,311,289 - 51,331,359 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,254,978 - 51,275,034 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,416,005 - 48,437,054 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,420,302 - 48,436,531 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,998,671 - 53,019,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4549,472,136 - 49,481,017 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1549,467,315 - 49,483,485 (-)NCBI
Celera546,322,990 - 46,344,463 (-)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Metabolite proofreading in carnosine and homocarnosine synthesis: molecular identification of PM20D2 as beta-alanyl-lysine dipeptidase. Veiga-da-Cunha M, etal., J Biol Chem. 2014 Jul 11;289(28):19726-36. doi: 10.1074/jbc.M114.576579. Epub 2014 Jun 2.
Additional References at PubMed
PMID:23376485  


Genomics

Comparative Map Data
Pm20d2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,362,384 - 52,382,647 (-)NCBIGRCr8
mRatBN7.2547,566,059 - 47,586,334 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,566,072 - 47,586,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,712,103 - 49,732,173 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,311,289 - 51,331,359 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,254,978 - 51,275,034 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,416,005 - 48,437,054 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,420,302 - 48,436,531 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,998,671 - 53,019,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4549,472,136 - 49,481,017 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1549,467,315 - 49,483,485 (-)NCBI
Celera546,322,990 - 46,344,463 (-)NCBICelera
Cytogenetic Map5q21NCBI
PM20D2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,093,940 - 89,165,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,146,055 - 89,165,565 (+)EnsemblGRCh38hg38GRCh38
GRCh37689,855,774 - 89,875,284 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36689,912,488 - 89,932,003 (+)NCBINCBI36Build 36hg18NCBI36
Celera690,273,652 - 90,293,174 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,071,380 - 87,091,359 (+)NCBIHuRef
CHM1_1689,953,721 - 89,973,244 (+)NCBICHM1_1
T2T-CHM13v2.0690,329,918 - 90,374,228 (+)NCBIT2T-CHM13v2.0
Pm20d2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39433,170,309 - 33,189,732 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl433,174,230 - 33,189,737 (-)EnsemblGRCm39 Ensembl
GRCm38433,170,401 - 33,189,737 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl433,174,230 - 33,189,737 (-)EnsemblGRCm38mm10GRCm38
MGSCv37433,257,376 - 33,276,712 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36433,510,233 - 33,518,350 (-)NCBIMGSCv36mm8
Celera432,921,441 - 32,940,787 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.71NCBI
Pm20d2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541115,932,365 - 15,945,579 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541115,932,367 - 15,943,946 (+)NCBIChiLan1.0ChiLan1.0
PM20D2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,224,811 - 109,245,658 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,125,128 - 107,145,832 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,021,249 - 87,040,809 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,296,747 - 90,316,025 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,296,808 - 90,312,728 (+)Ensemblpanpan1.1panPan2
PM20D2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11248,402,912 - 48,416,239 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1248,339,346 - 48,415,732 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,209,331 - 48,222,232 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,209,225 - 49,222,198 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,209,124 - 49,222,655 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11248,527,261 - 48,540,363 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01248,425,713 - 48,438,831 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01248,617,962 - 48,631,084 (+)NCBIUU_Cfam_GSD_1.0
Pm20d2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494683,412,615 - 83,429,270 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365103,041,592 - 3,058,513 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365103,041,598 - 3,058,193 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PM20D2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,188,336 - 57,219,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,188,019 - 57,219,243 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2163,965,900 - 63,996,614 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PM20D2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11313,900,702 - 13,922,217 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1313,902,015 - 13,919,532 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040190,217,625 - 190,239,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pm20d2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247995,011,394 - 5,025,734 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247995,010,153 - 5,025,154 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pm20d2
94 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:118
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000060914
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat

Markers in Region
D5Got222  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,579,719 - 47,579,947 (+)MAPPERmRatBN7.2
Rnor_6.0548,430,195 - 48,430,422NCBIRnor6.0
Rnor_5.0553,012,861 - 53,013,088UniSTSRnor5.0
RGSC_v3.4549,477,030 - 49,477,257UniSTSRGSC3.4
Celera546,336,647 - 46,336,874UniSTS
Cytogenetic Map5q21UniSTS
RH142708  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0553,002,637 - 53,002,739NCBIRnor5.0
RGSC_v3.4549,466,807 - 49,466,908UniSTSRGSC3.4
Celera546,326,424 - 46,326,525UniSTS
RH 3.4 Map5247.3UniSTS
Cytogenetic Map5q21UniSTS
RH141311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,566,270 - 47,566,471 (+)MAPPERmRatBN7.2
Rnor_6.0548,416,212 - 48,416,412NCBIRnor6.0
Rnor_5.0552,998,878 - 52,999,078UniSTSRnor5.0
RGSC_v3.4549,463,580 - 49,463,780UniSTSRGSC3.4
Celera546,323,197 - 46,323,397UniSTS
RH 3.4 Map5250.1UniSTS
Cytogenetic Map5q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 1 8 11 30 20 2 8
Low 3 43 52 37 18 37 44 15 39 11
Below cutoff 4 4 4

Sequence


RefSeq Acc Id: ENSRNOT00000060914   ⟹   ENSRNOP00000057636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl547,566,072 - 47,586,212 (-)Ensembl
Rnor_6.0 Ensembl548,420,302 - 48,436,531 (-)Ensembl
RefSeq Acc Id: NM_001107922   ⟹   NP_001101392
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,362,384 - 52,382,532 (-)NCBI
mRatBN7.2547,566,064 - 47,586,212 (-)NCBI
Rnor_6.0548,416,005 - 48,436,747 (-)NCBI
Rnor_5.0552,998,671 - 53,019,507 (-)NCBI
RGSC_v3.4549,472,136 - 49,481,017 (-)RGD
Celera546,322,990 - 46,344,463 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063287585   ⟹   XP_063143655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,363,513 - 52,382,642 (-)NCBI
RefSeq Acc Id: XR_005504433
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,373,579 - 52,382,647 (-)NCBI
mRatBN7.2547,570,290 - 47,586,334 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101392 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143655 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98582 (Get FASTA)   NCBI Sequence Viewer  
  EDL98583 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057636
  ENSRNOP00000057636.2
RefSeq Acc Id: NP_001101392   ⟸   NM_001107922
- UniProtKB: D4AAB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057636   ⟸   ENSRNOT00000060914
RefSeq Acc Id: XP_063143655   ⟸   XM_063287585
- Peptide Label: isoform X1
Protein Domains
Peptidase M20 dimerisation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAB5-F1-model_v2 AlphaFold D4AAB5 1-431 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307853 AgrOrtholog
BioCyc Gene G2FUF-41697 BioCyc
Ensembl Genes ENSRNOG00000007755 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060914 ENTREZGENE
  ENSRNOT00000060914.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.360 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro Amidohydrolase UniProtKB/TrEMBL
  Bact_exopeptidase_dim_dom UniProtKB/TrEMBL
  Pept_M20D_amidohydro_pred UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/TrEMBL
  Peptidase_M20_dimer UniProtKB/TrEMBL
KEGG Report rno:313130 UniProtKB/TrEMBL
NCBI Gene 313130 ENTREZGENE
PANTHER PEPTIDASE M20 UniProtKB/TrEMBL
  PEPTIDASE M20 DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam M20_dimer UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/TrEMBL
PhenoGen Pm20d2 PhenoGen
PIRSF Amidohydrolase_ACY1L2_prd UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007755 RatGTEx
Superfamily-SCOP Peptidase_M20_dimer UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt D4AAB5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-08 Pm20d2  peptidase M20 domain containing 2  Acy1l2  aminoacylase 1-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-10 Acy1l2  aminoacylase 1-like 2  Acy1l2_predicted  aminoacylase 1-like 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Acy1l2_predicted  aminoacylase 1-like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED