(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of UBE2I mRNA CTD PMID:17971868 (S)-nicotine decreases expression ISO RGD:734464 6480464 Nicotine results in decreased expression of UBE2I mRNA CTD PMID:18247414 1,2-dichloroethane increases expression ISO RGD:11469 6480464 ethylene dichloride results in increased expression of UBE2I mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO RGD:11469 6480464 1, 2-Dimethylhydrazine results in increased expression of UBE2I mRNA CTD PMID:22206623 1-chloro-2,4-dinitrobenzene affects binding ISO RGD:734464 6480464 Dinitrochlorobenzene binds to UBE2I protein CTD PMID:32991956 17beta-estradiol multiple interactions ISO RGD:734464 6480464 Estradiol promotes the reaction [UBE2I protein binds to ESR1 protein] CTD PMID:15666801 1H-pyrazole increases expression ISO RGD:11469 6480464 pyrazole results in increased expression of UBE2I mRNA CTD PMID:17945193 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:11469 6480464 UBE2I promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:23997114 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of UBE2I mRNA CTD PMID:21346803 2-naphthylamine increases expression ISO RGD:734464 6480464 2-Naphthylamine results in increased expression of UBE2I mRNA CTD PMID:18247414 4-hydroxynon-2-enal increases expression ISO RGD:11469 6480464 4-hydroxy-2-nonenal results in increased expression of UBE2I mRNA CTD PMID:19191707 acrylamide decreases expression ISO RGD:11469 6480464 Acrylamide results in decreased expression of UBE2I mRNA CTD PMID:21319176 aflatoxin B1 increases expression ISO RGD:734464 6480464 Aflatoxin B1 results in increased expression of UBE2I mRNA CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:734464 6480464 Tretinoin results in increased expression of UBE2I mRNA CTD PMID:23724009 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of UBE2I mRNA CTD PMID:16483693 antirheumatic drug increases expression ISO RGD:734464 6480464 Antirheumatic Agents results in increased expression of UBE2I mRNA CTD PMID:24449571 arsane affects methylation ISO RGD:734464 6480464 Arsenic affects the methylation of UBE2I gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:734464 6480464 Arsenic affects the methylation of UBE2I gene CTD PMID:25304211 arsenous acid multiple interactions ISO RGD:734464 6480464 [Arsenic Trioxide promotes the reaction [UBE2I protein binds to PML protein]] which results in increased sumoylation of PML protein more ... CTD PMID:20378816 , PMID:32240679 benzo[a]pyrene increases expression ISO RGD:11469 6480464 Benzo(a)pyrene results in increased expression of UBE2I mRNA CTD PMID:19770486 , PMID:20504355 benzo[a]pyrene affects methylation ISO RGD:734464 6480464 Benzo(a)pyrene affects the methylation of UBE2I 3' UTR CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:734464 6480464 Benzo(a)pyrene results in decreased expression of UBE2I mRNA CTD PMID:18247414 bilirubin IXalpha decreases expression ISO RGD:734464 6480464 Bilirubin results in decreased expression of UBE2I mRNA CTD PMID:20196124 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of UBE2I mRNA CTD PMID:21318169 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of UBE2I mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:11469 6480464 bisphenol A results in increased expression of UBE2I mRNA CTD PMID:33221593 bisphenol A increases expression ISO RGD:734464 6480464 bisphenol A results in increased expression of UBE2I mRNA CTD PMID:30426790 calcium atom affects expression EXP 6480464 Calcium affects the expression of UBE2I mRNA CTD PMID:15913539 calcium(0) affects expression EXP 6480464 Calcium affects the expression of UBE2I mRNA CTD PMID:15913539 CARBENOXOLONE multiple interactions EXP 6480464 Carbenoxolone inhibits the reaction [Sodium Glutamate results in decreased expression of UBE2I protein] CTD PMID:31077719 carbon nanotube increases expression ISO RGD:11469 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO RGD:734464 6480464 CGP 52608 promotes the reaction [RORA protein binds to UBE2I gene] CTD PMID:28238834 chlorpyrifos increases expression ISO RGD:11469 6480464 Chlorpyrifos results in increased expression of UBE2I mRNA CTD PMID:20350560 cholesterol multiple interactions ISO RGD:734464 6480464 UBE2I protein inhibits the reaction [Lipopolysaccharides results in increased abundance of Cholesterol] CTD PMID:33677747 ciguatoxin CTX1B affects expression ISO RGD:11469 6480464 Ciguatoxins affects the expression of UBE2I mRNA CTD PMID:18353800 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of UBE2I mRNA CTD PMID:21318169 cocaine increases expression ISO RGD:734464 6480464 Cocaine results in increased expression of UBE2I mRNA CTD PMID:12629581 copper atom multiple interactions ISO RGD:734464 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of UBE2I protein CTD PMID:20931265 copper(0) multiple interactions ISO RGD:734464 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of UBE2I protein CTD PMID:20931265 D-gluconic acid multiple interactions EXP 6480464 [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of UBE2I mRNA CTD PMID:16556975 deoxycholic acid multiple interactions EXP 6480464 [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of UBE2I mRNA CTD PMID:16556975 dexamethasone multiple interactions ISO RGD:11469 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein]], Dexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein] CTD PMID:20671745 diarsenic trioxide multiple interactions ISO RGD:734464 6480464 [Arsenic Trioxide promotes the reaction [UBE2I protein binds to PML protein]] which results in increased sumoylation of PML protein more ... CTD PMID:20378816 , PMID:32240679 dibutyl phthalate decreases expression ISO RGD:11469 6480464 Dibutyl Phthalate results in decreased expression of UBE2I mRNA CTD PMID:21266533 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of UBE2I protein, Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of UBE2I protein] CTD PMID:34174262 dorsomorphin multiple interactions ISO RGD:734464 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:11469 6480464 Doxorubicin results in increased expression of UBE2I mRNA CTD PMID:25896364 doxorubicin decreases expression ISO RGD:734464 6480464 Doxorubicin results in decreased expression of UBE2I mRNA CTD PMID:29803840 emodin increases expression ISO RGD:11469 6480464 Emodin results in increased expression of UBE2I mRNA CTD PMID:21319176 endosulfan increases expression ISO RGD:734464 6480464 Endosulfan results in increased expression of UBE2I mRNA CTD PMID:30426790 ethanol affects splicing ISO RGD:11469 6480464 Ethanol affects the splicing of UBE2I mRNA CTD PMID:30319688 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of UBE2I mRNA CTD PMID:34044035 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of UBE2I mRNA CTD PMID:18035473 folic acid increases expression ISO RGD:11469 6480464 Folic Acid results in increased expression of UBE2I mRNA CTD PMID:25629700 genistein increases expression ISO RGD:11469 6480464 Genistein results in increased expression of UBE2I mRNA CTD PMID:32186404 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of UBE2I mRNA CTD PMID:22061828 ivermectin decreases expression ISO RGD:734464 6480464 Ivermectin results in decreased expression of UBE2I protein CTD PMID:32959892 lipopolysaccharide decreases expression ISO RGD:734464 6480464 Lipopolysaccharides results in decreased expression of UBE2I mRNA, Lipopolysaccharides results in decreased expression of UBE2I protein CTD PMID:33677747 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of UBE2I protein CTD PMID:33677747 lipopolysaccharide multiple interactions EXP 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2I protein] CTD PMID:33677747 lipopolysaccharide multiple interactions ISO RGD:734464 6480464 MIR590 mRNA inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2I protein] more ... CTD PMID:33677747 methotrexate decreases expression ISO RGD:734464 6480464 Methotrexate results in decreased expression of UBE2I mRNA CTD PMID:24449571 methylmercury chloride increases expression ISO RGD:11469 6480464 methylmercuric chloride results in increased expression of UBE2I mRNA CTD PMID:20061341 methylmercury chloride increases expression ISO RGD:734464 6480464 methylmercuric chloride results in increased expression of UBE2I mRNA CTD PMID:28001369 mevinphos multiple interactions EXP 6480464 Mevinphos results in increased expression of and results in increased activity of UBE2I protein, UBE2I protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein] CTD PMID:21390240 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of UBE2I protein CTD PMID:31077719 monosodium L-glutamate multiple interactions EXP 6480464 Carbenoxolone inhibits the reaction [Sodium Glutamate results in decreased expression of UBE2I protein] CTD PMID:31077719 nicotine decreases expression ISO RGD:734464 6480464 Nicotine results in decreased expression of UBE2I mRNA CTD PMID:18247414 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of UBE2I mRNA CTD PMID:24136188 paracetamol affects expression ISO RGD:11469 6480464 Acetaminophen affects the expression of UBE2I mRNA CTD PMID:17562736 pentachlorophenol increases expression ISO RGD:11469 6480464 Pentachlorophenol results in increased expression of UBE2I mRNA CTD PMID:23892564 phenobarbital decreases expression ISO RGD:11469 6480464 Phenobarbital results in decreased expression of UBE2I mRNA CTD PMID:23091169 phenylmercury acetate decreases expression ISO RGD:734464 6480464 Phenylmercuric Acetate results in decreased expression of UBE2I mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:734464 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UBE2I mRNA CTD PMID:27188386 phlorizin decreases expression ISO RGD:11469 6480464 Phlorhizin results in decreased expression of UBE2I mRNA CTD PMID:22538082 pirinixic acid multiple interactions ISO RGD:734464 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of UBE2I mRNA CTD PMID:19710929 pirinixic acid increases expression ISO RGD:11469 6480464 pirinixic acid results in increased expression of UBE2I mRNA CTD PMID:23811191 prasugrel hydrochloride multiple interactions EXP 6480464 Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of UBE2I protein] CTD PMID:34174262 propiconazole decreases expression ISO RGD:11469 6480464 propiconazole results in decreased expression of UBE2I mRNA CTD PMID:21278054 rifampicin multiple interactions EXP 6480464 UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:28132806 SB 431542 multiple interactions ISO RGD:734464 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sodium arsenate increases expression ISO RGD:11469 6480464 sodium arsenate results in increased expression of UBE2I mRNA CTD PMID:21795629 succimer multiple interactions ISO RGD:11469 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of UBE2I mRNA CTD PMID:26378955 sunitinib decreases expression ISO RGD:734464 6480464 Sunitinib results in decreased expression of UBE2I mRNA CTD PMID:31533062 thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of UBE2I protein CTD PMID:35544339 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of UBE2I protein CTD PMID:33677747 topotecan affects response to substance ISO RGD:734464 6480464 UBE2I protein affects the susceptibility to Topotecan CTD PMID:16217747 trichostatin A decreases expression ISO RGD:734464 6480464 trichostatin A results in decreased expression of UBE2I mRNA CTD PMID:26272509 trichostatin A multiple interactions ISO RGD:734464 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UBE2I mRNA CTD PMID:27188386 trovafloxacin multiple interactions ISO RGD:11469 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of UBE2I mRNA CTD PMID:18930950 valproic acid increases methylation ISO RGD:734464 6480464 Valproic Acid results in increased methylation of UBE2I gene CTD PMID:29154799 valproic acid increases expression ISO RGD:734464 6480464 Valproic Acid results in increased expression of UBE2I mRNA CTD PMID:23179753 vincristine decreases expression ISO RGD:734464 6480464 Vincristine results in decreased expression of UBE2I mRNA CTD PMID:23649840 vorinostat decreases expression ISO RGD:734464 6480464 vorinostat results in decreased expression of UBE2I protein CTD PMID:20543569 zinc sulfate increases expression ISO RGD:734464 6480464 Zinc Sulfate results in increased expression of UBE2I mRNA CTD PMID:12756304
