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Gene: Ube2i (ubiquitin-conjugating enzyme E2I) Mus musculus
Symbol: Ube2i
Name: ubiquitin-conjugating enzyme E2I
Description: Exhibits HLH domain binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of I-kappaB kinase/NF-kappaB signaling. Localizes to nuclear body. Is expressed in several structures, including blastocyst; early embryo; forebrain; limb; and oocyte. Orthologous to human UBE2I (ubiquitin conjugating enzyme E2 I); PARTICIPATES IN aldosterone signaling pathway; altered ubiquitin/proteasome degradation pathway; Alzheimer's disease pathway; INTERACTS WITH 1,2-dichloroethane; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830467E05Rik; F830028O17Rik; Mmubc9; RIKEN cDNA F830028O17 gene; RING-type E3 SUMO transferase UBC9; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; UBC9; Ubce2i; Ubce9; ubiquitin carrier protein 9; ubiquitin carrier protein I; ubiquitin-protein ligase I
Homo sapiens (human) : UBE2I (ubiquitin conjugating enzyme E2 I)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ube2i (ubiquitin-conjugating enzyme E2I)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube2i (ubiquitin conjugating enzyme E2 I)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE2I (ubiquitin conjugating enzyme E2 I)
Canis lupus familiaris (dog) : UBE2I (ubiquitin conjugating enzyme E2 I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube2i (ubiquitin conjugating enzyme E2 I)
Sus scrofa (pig) : UBE2I (ubiquitin conjugating enzyme E2 I)
Chlorocebus sabaeus (African green monkey) : UBE2I (ubiquitin conjugating enzyme E2 I)
Heterocephalus glaber (naked mole-rat) : Ube2i (ubiquitin conjugating enzyme E2 I)
more info ...
Related Pseudogenes: Gm14176   Gm2140   Gm5931   Gm8051   Ube2i-ps1   Ube2i-ps2   Ube2i-ps3  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1725,261,916 - 25,274,622 (-)EnsemblGRCm38mm10GRCm38
GRCm381725,260,510 - 25,275,799 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371725,397,456 - 25,411,255 (-)NCBIGRCm37mm9NCBIm37
MGSCv361724,988,111 - 25,001,891 (-)NCBImm8
Celera1725,787,805 - 25,801,616 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ube2i
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11469
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.