Mir101a (microRNA 101a) - Rat Genome Database

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Gene: Mir101a (microRNA 101a) Rattus norvegicus
Analyze
Symbol: Mir101a
Name: microRNA 101a
RGD ID: 2325348
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including negative regulation of necroptotic process; negative regulation of protein metabolic process; and negative regulation of signal transduction. Predicted to act upstream of or within cellular response to amino acid stimulus; long-term synaptic potentiation; and positive regulation of gene expression. Predicted to be located in synapse. Predicted to be part of RISC complex. Orthologous to human MIR101-1 (microRNA 101-1); INTERACTS WITH atrazine; bisphenol A; bleomycin A2.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-101a; rno-mir-101a
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85121,081,683 - 121,081,757 (-)NCBIGRCr8
mRatBN7.25115,966,332 - 115,966,406 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5115,966,328 - 115,966,410 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5118,524,277 - 118,524,351 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05120,249,646 - 120,249,720 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05120,300,933 - 120,301,007 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05120,168,437 - 120,168,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5120,168,433 - 120,168,515 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05124,050,126 - 124,050,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5114,503,665 - 114,503,739 (-)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (ISO)
synapse  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16766679   PMID:17604727   PMID:20395292   PMID:20403161   PMID:20548288   PMID:23185045   PMID:23227940   PMID:23390134   PMID:25591764   PMID:25858512   PMID:25921548  
PMID:26498873   PMID:27762633   PMID:30053527   PMID:31746349   PMID:32572927   PMID:32656992   PMID:32894531   PMID:33559830   PMID:33955520   PMID:34650661   PMID:36336032   PMID:37584866  
PMID:38739522  


Genomics

Comparative Map Data
Mir101a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85121,081,683 - 121,081,757 (-)NCBIGRCr8
mRatBN7.25115,966,332 - 115,966,406 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5115,966,328 - 115,966,410 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5118,524,277 - 118,524,351 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05120,249,646 - 120,249,720 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05120,300,933 - 120,301,007 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05120,168,437 - 120,168,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5120,168,433 - 120,168,515 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05124,050,126 - 124,050,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5114,503,665 - 114,503,739 (-)NCBICelera
Cytogenetic Map5q33NCBI
MIR101-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38165,058,434 - 65,058,508 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl165,058,434 - 65,058,508 (-)EnsemblGRCh38hg38GRCh38
GRCh37165,524,117 - 65,524,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36165,296,704 - 65,296,778 (-)NCBINCBI36Build 36hg18NCBI36
Celera163,814,935 - 63,815,009 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef163,633,008 - 63,633,082 (-)NCBIHuRef
CHM1_1165,640,418 - 65,640,492 (-)NCBICHM1_1
T2T-CHM13v2.0164,936,444 - 64,936,518 (-)NCBIT2T-CHM13v2.0
Mir101a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394101,204,142 - 101,204,224 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4101,204,142 - 101,204,224 (-)EnsemblGRCm39 Ensembl
GRCm384101,346,945 - 101,347,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4101,346,945 - 101,347,027 (-)EnsemblGRCm38mm10GRCm38
MGSCv374101,019,550 - 101,019,632 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera499,688,603 - 99,688,685 (-)NCBICelera
Cytogenetic Map4C6NCBI
cM Map446.67NCBI
MIR101-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1545,184,774 - 45,184,828 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl545,184,759 - 45,184,841 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha545,243,212 - 45,243,266 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0545,367,400 - 45,367,454 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl545,367,385 - 45,367,467 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1545,334,232 - 45,334,286 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0545,278,191 - 45,278,245 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0545,528,068 - 45,528,122 (+)NCBIUU_Cfam_GSD_1.0
MIR101-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6147,330,890 - 147,330,972 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16147,330,891 - 147,330,971 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26135,736,115 - 135,736,195 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status (No longer updated)

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Capn8rno-miR-101a-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:6541
Count of gene targets:4357
Count of transcripts:4688
Interacting mature miRNAs:rno-miR-101a-3p, rno-miR-101a-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
7794743Bp373Blood pressure QTL 3730.0058arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5112175546116047089Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 9 11 52 22 26 7 18 7 64 38 45 10 12 19

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000053722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5115,966,328 - 115,966,410 (-)Ensembl
Rnor_6.0 Ensembl5120,168,433 - 120,168,515 (-)Ensembl
RefSeq Acc Id: NR_031859
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85121,081,683 - 121,081,757 (-)NCBI
mRatBN7.25115,966,332 - 115,966,406 (-)NCBI
Rnor_6.05120,168,437 - 120,168,511 (-)NCBI
Rnor_5.05124,050,126 - 124,050,200 (-)NCBI
Celera5114,503,665 - 114,503,739 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325348 AgrOrtholog
BioCyc Gene G2FUF-40542 BioCyc
Ensembl Genes ENSRNOG00000035599 Ensembl
miRBase MI0000886 ENTREZGENE
NCBI Gene 100314279 ENTREZGENE
PhenoGen Mir101a PhenoGen
RatGTEx ENSRNOG00000035599 RatGTEx
RNAcentral URS00001230A0 RNACentral
  URS000016B83E RNACentral
  URS00004D302A RNACentral
  URS0000759A58 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-08-15 Mir101a  microRNA 101a  Mir101a  microRNA mir-101a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir101a  microRNA mir-101a      Symbol and Name status set to provisional 70820 PROVISIONAL