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Gene: Siah2 (siah E3 ubiquitin protein ligase 2) Rattus norvegicus
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Symbol: Siah2
Name: siah E3 ubiquitin protein ligase 2
Description: Exhibits ubiquitin conjugating enzyme binding activity. Involved in regulation of protein ubiquitination. Localizes to several cellular components, including the cytosol; early endosome; and neuronal cell body. Orthologous to human SIAH2 (siah E3 ubiquitin protein ligase 2); PARTICIPATES IN estrogen signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase SIAH2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah-2
Orthologs:
Homo sapiens (human) : SIAH2 (siah E3 ubiquitin protein ligase 2)  HGNC  Alliance
Mus musculus (house mouse) : Siah2 (siah E3 ubiquitin protein ligase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Siah2 (siah E3 ubiquitin protein ligase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SIAH2 (siah E3 ubiquitin protein ligase 2)
Canis lupus familiaris (dog) : SIAH2 (siah E3 ubiquitin protein ligase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Siah2 (siah E3 ubiquitin protein ligase 2)
Sus scrofa (pig) : SIAH2 (siah E3 ubiquitin protein ligase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02148,874,151 - 148,891,900 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2148,874,151 - 148,891,900 (-)Ensembl
Rnor_5.02168,292,053 - 168,309,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42148,022,641 - 148,040,390 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12147,972,605 - 147,990,353 (-)NCBI
Celera2137,342,181 - 137,359,932 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Siah2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620778
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.