Exog (exo/endonuclease G) - Rat Genome Database

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Gene: Exog (exo/endonuclease G) Rattus norvegicus
Analyze
Symbol: Exog
Name: exo/endonuclease G
RGD ID: 1304628
Description: Predicted to enable 5'-3' exonuclease activity; endoribonuclease activity; and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in apoptotic DNA fragmentation. Predicted to be located in mitochondrion. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrial inner membrane and nucleus. Orthologous to human EXOG (exo/endonuclease G); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: endo/exonuclease (5'-3'), endonuclease G-like; Endogl1; endonuclease G-like 1; LOC301062; nuclease EXOG, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28119,184,974 - 119,204,819 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,185,136 - 119,204,672 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8124,766,920 - 124,786,632 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08122,965,942 - 122,985,654 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08120,799,635 - 120,819,356 (+)NCBIRnor_WKY
Rnor_6.08128,133,398 - 128,153,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,133,431 - 128,153,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,340,128 - 127,360,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,410,416 - 124,430,163 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18124,430,195 - 124,446,969 (+)NCBI
Celera8118,336,037 - 118,355,751 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18187503   PMID:18614015   PMID:25378300   PMID:27417117   PMID:33515431  


Genomics

Comparative Map Data
Exog
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28119,184,974 - 119,204,819 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,185,136 - 119,204,672 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8124,766,920 - 124,786,632 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08122,965,942 - 122,985,654 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08120,799,635 - 120,819,356 (+)NCBIRnor_WKY
Rnor_6.08128,133,398 - 128,153,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,133,431 - 128,153,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,340,128 - 127,360,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,410,416 - 124,430,163 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18124,430,195 - 124,446,969 (+)NCBI
Celera8118,336,037 - 118,355,751 (+)NCBICelera
Cytogenetic Map8q32NCBI
EXOG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38338,496,340 - 38,526,303 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl338,496,127 - 38,542,161 (+)EnsemblGRCh38hg38GRCh38
GRCh37338,537,831 - 38,567,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,512,837 - 38,541,183 (+)NCBINCBI36Build 36hg18NCBI36
Build 34338,512,836 - 38,541,183NCBI
Celera338,473,645 - 38,503,721 (+)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef338,580,009 - 38,610,042 (+)NCBIHuRef
CHM1_1338,489,402 - 38,519,435 (+)NCBICHM1_1
T2T-CHM13v2.0338,502,384 - 38,532,347 (+)NCBIT2T-CHM13v2.0
Exog
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,273,992 - 119,294,584 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,274,009 - 119,294,583 (+)EnsemblGRCm39 Ensembl
GRCm389119,444,925 - 119,465,518 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,444,943 - 119,465,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv379119,354,041 - 119,374,636 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369119,293,658 - 119,312,928 (+)NCBIMGSCv36mm8
Celera9119,915,149 - 119,935,877 (+)NCBICelera
Cytogenetic Map9F3NCBI
Exog
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542725,394,019 - 25,426,930 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542725,394,019 - 25,426,930 (-)NCBIChiLan1.0ChiLan1.0
EXOG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1338,674,970 - 38,703,750 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,674,970 - 38,703,750 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0338,392,968 - 38,422,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
EXOG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1238,231,469 - 8,260,572 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl238,231,484 - 8,258,710 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,271,601 - 8,300,194 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0238,520,487 - 8,549,097 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl238,520,502 - 8,549,097 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1238,334,334 - 8,362,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,474,827 - 8,503,623 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0238,468,262 - 8,496,874 (+)NCBIUU_Cfam_GSD_1.0
Exog
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118194,696,462 - 194,724,401 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647327,835,065 - 27,862,966 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,278,932 - 23,307,566 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11323,278,458 - 23,330,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,463,770 - 25,510,239 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXOG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115892,860 - 920,371 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl15893,055 - 919,994 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660639,623,778 - 9,650,559 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exog
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247312,514,513 - 2,550,617 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247312,515,294 - 2,550,531 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH128550  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,202,560 - 119,202,756 (+)MAPPERmRatBN7.2
Rnor_6.08128,150,854 - 128,151,049NCBIRnor6.0
Rnor_5.08127,357,813 - 127,358,008UniSTSRnor5.0
RGSC_v3.48124,427,907 - 124,428,102UniSTSRGSC3.4
Celera8118,353,491 - 118,353,686UniSTS
RH 3.4 Map81287.3UniSTS
Cytogenetic Map8q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:334
Count of miRNA genes:193
Interacting mature miRNAs:245
Transcripts:ENSRNOT00000020174
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7 2 5 2 52 12 16
Low 3 43 50 39 14 39 8 11 22 23 25 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000020174   ⟹   ENSRNOP00000020174
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8119,185,136 - 119,204,672 (+)Ensembl
Rnor_6.0 Ensembl8128,133,431 - 128,153,110 (+)Ensembl
RefSeq Acc Id: NM_001106866   ⟹   NP_001100336
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,185,136 - 119,204,819 (+)NCBI
Rnor_6.08128,133,431 - 128,153,110 (+)NCBI
Rnor_5.08127,340,128 - 127,360,069 (+)NCBI
RGSC_v3.48124,410,416 - 124,430,163 (+)RGD
Celera8118,336,037 - 118,355,751 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244088   ⟹   XP_006244150
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,184,974 - 119,202,807 (+)NCBI
Rnor_6.08128,133,398 - 128,151,899 (+)NCBI
Rnor_5.08127,340,128 - 127,360,069 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081300   ⟹   XP_038937228
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,187,847 - 119,202,807 (+)NCBI
RefSeq Acc Id: XR_005487802
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,184,974 - 119,191,505 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100336   ⟸   NM_001106866
- UniProtKB: D3ZTW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244150   ⟸   XM_006244088
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000020174   ⟸   ENSRNOT00000020174
RefSeq Acc Id: XP_038937228   ⟸   XM_039081300
- Peptide Label: isoform X2
Protein Domains
Endonuclease_NS   NUC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTW9-F1-model_v2 AlphaFold D3ZTW9 1-368 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696373
Promoter ID:EPDNEW_R6898
Type:multiple initiation site
Name:Exog_1
Description:exo/endonuclease G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08128,133,446 - 128,133,506EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 128133814 128133815 T A snv GH/OmrMcwi (MCW), WAG/RijCrl (2020), MR/N (MCW), LE/Stm (RGD), WAG/Rij (RGD), FXLE16/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), M520/N (MCW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 127340528 127340529 T A snv GH/OmrMcwi (MCW), MR/N (KNAW), M520/N (KNAW), LE/Stm (Illumina) (KNAW), LE/Stm (SOLiD) (KNAW), WAG/Rij (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304628 AgrOrtholog
BioCyc Gene G2FUF-28786 BioCyc
Ensembl Genes ENSRNOG00000014801 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020174 ENTREZGENE
  ENSRNOP00000020174.4 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020174 ENTREZGENE
  ENSRNOT00000020174.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.570.10 UniProtKB/TrEMBL
InterPro DNA/RNA_non-sp_Endonuclease UniProtKB/TrEMBL
  DNA/RNA_non-sp_Endonuclease_sf UniProtKB/TrEMBL
  Exog_C UniProtKB/TrEMBL
  Extracellular_endonuc_su_A UniProtKB/TrEMBL
  His-Me_finger_sf UniProtKB/TrEMBL
  Non-specific_endonuclease UniProtKB/TrEMBL
KEGG Report rno:301062 UniProtKB/TrEMBL
NCBI Gene 301062 ENTREZGENE
PANTHER PTHR13966 UniProtKB/TrEMBL
Pfam Endonuclease_NS UniProtKB/TrEMBL
  Exog_C UniProtKB/TrEMBL
PhenoGen Exog PhenoGen
SMART Endonuclease_NS UniProtKB/TrEMBL
  NUC UniProtKB/TrEMBL
Superfamily-SCOP SSF54060 UniProtKB/TrEMBL
UniProt D3ZTW9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 Exog  exo/endonuclease G  Exog  endo/exonuclease (5'-3'), endonuclease G-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-23 Exog  endo/exonuclease (5'-3'), endonuclease G-like  Endogl1  endonuclease G-like 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Endogl1  endonuclease G-like 1   Endogl1_predicted  endonuclease G-like 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Endogl1_predicted  endonuclease G-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED