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Gene: Tbc1d8b (TBC1 domain family member 8B) Rattus norvegicus
Symbol: Tbc1d8b
Name: TBC1 domain family member 8B
Description: Predicted to have GTPase activator activity and Rab GTPase binding activity. Predicted to be involved in several processes, including activation of GTPase activity; glomerular filtration; and intracellular protein transport. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Orthologous to human TBC1D8B (TBC1 domain family member 8B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315912; RGD1563084; similar to FLJ20298 protein isoform a; TBC1 domain family, member 8B (with GRAM domain)
Homo sapiens (human) : TBC1D8B (TBC1 domain family member 8B)  HGNC  Alliance
Mus musculus (house mouse) : Tbc1d8b (TBC1 domain family, member 8B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbc1d8b (TBC1 domain family member 8B)
Pan paniscus (bonobo/pygmy chimpanzee) : TBC1D8B (TBC1 domain family member 8B)
Canis lupus familiaris (dog) : TBC1D8B (TBC1 domain family member 8B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbc1d8b (TBC1 domain family member 8B)
Sus scrofa (pig) : TBC1D8B (TBC1 domain family member 8B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X110,894,831 - 110,983,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX110,894,845 - 110,983,309 (+)Ensembl
Rnor_5.0353,608,955 - 53,698,013 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X127,388,586 - 127,484,707 (+)NCBIRGSC3.4rn4RGSC3.4
Celera344,520,022 - 44,607,073 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tbc1d8b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563084
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.