(+)-catechin multiple interactions ISO RGD:1351986 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of APLN mRNA CTD PMID:24763279 (R)-lipoic acid multiple interactions ISO RGD:1332289 6480464 acadesine inhibits the reaction [Thioctic Acid results in increased expression of APLN mRNA], acadesine inhibits the reaction [Thioctic Acid results in increased secretion of APLN protein] CTD PMID:21461750 (R)-lipoic acid increases secretion ISO RGD:1332289 6480464 Thioctic Acid results in increased secretion of APLN protein CTD PMID:21461750 (R)-lipoic acid increases expression ISO RGD:1332289 6480464 Thioctic Acid results in increased expression of APLN mRNA CTD PMID:21461750 (S)-colchicine decreases expression EXP 6480464 Colchicine results in decreased expression of APLN mRNA CTD PMID:20624997 1,2-dimethylhydrazine increases expression ISO RGD:1332289 6480464 1, 2-Dimethylhydrazine results in increased expression of APLN mRNA CTD PMID:22206623 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of APLN mRNA CTD PMID:17557909 17beta-estradiol multiple interactions ISO RGD:1351986 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of APLN mRNA CTD PMID:30165855 17beta-estradiol decreases expression ISO RGD:1351986 6480464 Estradiol results in decreased expression of APLN mRNA CTD PMID:32030086 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1332289 6480464 Tetrachlorodibenzodioxin affects the expression of APLN mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of APLN mRNA CTD PMID:32109520 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:1332289 6480464 tetrabromobisphenol A results in decreased expression of APLN mRNA CTD PMID:25172293 3,3',5,5'-tetrabromobisphenol A multiple interactions ISO RGD:1351986 6480464 tetrabromobisphenol A results in increased expression of and results in increased secretion of APLN protein CTD PMID:28111160 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1351986 6480464 tetrabromobisphenol A results in increased expression of APLN mRNA CTD PMID:28111160 4-hydroxyphenyl retinamide increases expression ISO RGD:1332289 6480464 Fenretinide results in increased expression of APLN mRNA CTD PMID:28973697 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of APLN mRNA CTD PMID:24780913 , PMID:25825206 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:1332289 6480464 APLN protein modified form inhibits the reaction [Uric Acid results in decreased activity of CAT protein] more ... CTD PMID:30710622 acadesine multiple interactions ISO RGD:1332289 6480464 acadesine inhibits the reaction [Thioctic Acid results in increased expression of APLN mRNA], acadesine inhibits the reaction [Thioctic Acid results in increased secretion of APLN protein] CTD PMID:21461750 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of APLN mRNA CTD PMID:28959563 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of APLN mRNA CTD PMID:16483693 benzo[a]pyrene increases expression ISO RGD:1332289 6480464 Benzo(a)pyrene results in increased expression of APLN mRNA CTD PMID:22610609 benzo[a]pyrene increases methylation ISO RGD:1351986 6480464 Benzo(a)pyrene results in increased methylation of APLN 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:1351986 6480464 Benzo(a)pyrene affects the methylation of APLN promoter CTD PMID:27901495 benzo[b]fluoranthene decreases expression ISO RGD:1332289 6480464 benzo(b)fluoranthene results in decreased expression of APLN mRNA CTD PMID:26377693 Benzo[ghi]perylene increases expression ISO RGD:1332289 6480464 1, 12-benzoperylene results in increased expression of APLN mRNA CTD PMID:26377693 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of APLN mRNA CTD PMID:18164116 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of APLN mRNA CTD PMID:18180321 bisphenol A decreases expression ISO RGD:1351986 6480464 bisphenol A results in decreased expression of APLN mRNA CTD PMID:32030086 bisphenol A multiple interactions ISO RGD:1351986 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [bisphenol A results in increased expression of APLN mRNA] more ... CTD PMID:28111160 bisphenol A increases expression ISO RGD:1351986 6480464 bisphenol A results in increased expression of APLN mRNA CTD PMID:27685785 , PMID:28111160 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of APLN mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:1332289 6480464 bisphenol A results in decreased expression of APLN mRNA CTD PMID:26063408 BQ 123 multiple interactions ISO RGD:1332289 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased expression of APLN mRNA] CTD PMID:25203536 cadmium dichloride decreases expression ISO RGD:1332289 6480464 Cadmium Chloride results in decreased expression of APLN mRNA CTD PMID:24982889 carbon nanotube decreases expression ISO RGD:1332289 6480464 Nanotubes more ... CTD PMID:25554681 chloroprene decreases expression ISO RGD:1332289 6480464 Chloroprene results in decreased expression of APLN mRNA CTD PMID:23125180 clobetasol decreases expression ISO RGD:1332289 6480464 Clobetasol results in decreased expression of APLN mRNA CTD PMID:27462272 cobalt dichloride affects secretion ISO RGD:1332289 6480464 cobaltous chloride affects the secretion of APLN protein CTD PMID:17878221 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of APLN mRNA CTD PMID:24386269 cobalt dichloride decreases expression ISO RGD:1351986 6480464 cobaltous chloride results in decreased expression of APLN mRNA CTD PMID:19320972 cobalt dichloride multiple interactions ISO RGD:1332289 6480464 HIF1A gene mutant form inhibits the reaction [cobaltous chloride affects the secretion of APLN protein] CTD PMID:17878221 cobalt dichloride increases expression ISO RGD:1332289 6480464 cobaltous chloride results in increased expression of APLN mRNA, cobaltous chloride results in increased expression of APLN protein CTD PMID:17878221 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of APLN mRNA CTD PMID:26577399 , PMID:27523638 cypermethrin increases expression ISO RGD:1332289 6480464 cypermethrin results in increased expression of APLN mRNA CTD PMID:29020013 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of APLN mRNA CTD PMID:23640034 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of APLN mRNA CTD PMID:20032058 dexamethasone decreases expression ISO RGD:1351986 6480464 Dexamethasone results in decreased expression of APLN mRNA CTD PMID:19853017 dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in decreased expression of APLN mRNA] CTD PMID:20032058 dextran sulfate multiple interactions ISO RGD:1332289 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of APLN mRNA CTD PMID:29950665 dextran sulfate decreases expression ISO RGD:1332289 6480464 Dextran Sulfate results in decreased expression of APLN mRNA CTD PMID:35093514 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of APLN mRNA CTD PMID:24893172 dibutyl phthalate decreases expression ISO RGD:1332289 6480464 Dibutyl Phthalate results in decreased expression of APLN mRNA CTD PMID:17361019 , PMID:21266533 dioxygen increases expression ISO RGD:1332289 6480464 Oxygen deficiency results in increased expression of APLN mRNA more ... CTD PMID:17878221 , PMID:25203536 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of APLN mRNA CTD PMID:33729688 dioxygen increases expression ISO RGD:1351986 6480464 Oxygen deficiency results in increased expression of APLN mRNA CTD PMID:24236059 dioxygen increases secretion ISO RGD:1332289 6480464 Oxygen deficiency results in increased secretion of APLN protein CTD PMID:17878221 dioxygen multiple interactions ISO RGD:1332289 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased expression of APLN mRNA] more ... CTD PMID:17878221 , PMID:25203536 entinostat decreases expression ISO RGD:1351986 6480464 entinostat results in decreased expression of APLN mRNA CTD PMID:32870474 ethanol increases expression ISO RGD:1332289 6480464 Ethanol results in increased expression of APLN mRNA CTD PMID:30319688 fluoranthene multiple interactions ISO RGD:1332289 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of APLN mRNA CTD PMID:28329830 folic acid decreases expression ISO RGD:1332289 6480464 Folic Acid results in decreased expression of APLN mRNA CTD PMID:25629700 fructose multiple interactions EXP 6480464 APLN protein modified form inhibits the reaction [Fructose results in decreased activity of CAT protein] more ... CTD PMID:30710622 isoprenaline multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN mRNA], Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN protein] CTD PMID:19960946 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of APLN mRNA, Isoproterenol results in decreased expression of APLN protein CTD PMID:19960946 lipoic acid multiple interactions ISO RGD:1332289 6480464 acadesine inhibits the reaction [Thioctic Acid results in increased expression of APLN mRNA], acadesine inhibits the reaction [Thioctic Acid results in increased secretion of APLN protein] CTD PMID:21461750 lipoic acid increases secretion ISO RGD:1332289 6480464 Thioctic Acid results in increased secretion of APLN protein CTD PMID:21461750 lipoic acid increases expression ISO RGD:1332289 6480464 Thioctic Acid results in increased expression of APLN mRNA CTD PMID:21461750 LY294002 increases expression ISO RGD:1332289 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of APLN mRNA CTD PMID:21461750 LY294002 multiple interactions ISO RGD:1332289 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Eicosapentaenoic Acid results in increased expression of APLN mRNA] CTD PMID:20352620 LY294002 increases secretion ISO RGD:1332289 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased secretion of APLN protein CTD PMID:21461750 methotrexate decreases expression ISO RGD:1351986 6480464 Methotrexate results in decreased expression of APLN mRNA CTD PMID:17400583 methylmercury chloride increases expression ISO RGD:1351986 6480464 methylmercuric chloride results in increased expression of APLN mRNA CTD PMID:28001369 mono(2-ethylhexyl) phthalate affects expression ISO RGD:1332289 6480464 mono-(2-ethylhexyl)phthalate affects the expression of APLN mRNA CTD PMID:32522588 Muraglitazar increases expression EXP 6480464 muraglitazar results in increased expression of APLN mRNA CTD PMID:21515302 N-methyl-4-phenylpyridinium decreases expression ISO RGD:1351986 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of APLN mRNA CTD PMID:32870474 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of APLN mRNA CTD PMID:18164116 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of APLN mRNA CTD PMID:19041683 N-Nitrosopyrrolidine decreases expression ISO RGD:1351986 6480464 N-Nitrosopyrrolidine results in decreased expression of APLN mRNA CTD PMID:32234424 nickel atom decreases expression ISO RGD:1332289 6480464 Nickel results in decreased expression of APLN mRNA CTD PMID:12540486 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of APLN mRNA CTD PMID:22110744 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of APLN mRNA, nitrofen results in decreased expression of APLN protein CTD PMID:24363088 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of APLN mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of APLN mRNA CTD PMID:25729387 ozone increases methylation EXP 6480464 Ozone results in increased methylation of APLN promoter CTD PMID:29947284 ozone multiple interactions ISO RGD:1332289 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of APLN mRNA CTD PMID:34911549 ozone decreases expression EXP 6480464 Ozone results in decreased expression of APLN mRNA CTD PMID:29947284 paracetamol affects expression ISO RGD:1332289 6480464 Acetaminophen affects the expression of APLN mRNA CTD PMID:17562736 paraquat decreases expression ISO RGD:1351986 6480464 Paraquat results in decreased expression of APLN mRNA CTD PMID:32870474 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of APLN mRNA CTD PMID:32680482 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of APLN mRNA CTD PMID:25710175 pirinixic acid decreases expression ISO RGD:1332289 6480464 pirinixic acid results in decreased expression of APLN mRNA CTD PMID:17950772 pirinixic acid increases expression ISO RGD:1332289 6480464 pirinixic acid results in increased expression of APLN mRNA CTD PMID:20813756 quercetin affects expression EXP 6480464 Quercetin affects the expression of APLN mRNA CTD PMID:18178720 resveratrol increases expression ISO RGD:1332289 6480464 resveratrol metabolite results in increased expression of APLN mRNA, resveratrol results in increased expression of APLN mRNA CTD PMID:23717508 resveratrol multiple interactions ISO RGD:1351986 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of APLN mRNA CTD PMID:23557933 rotenone multiple interactions ISO RGD:1332289 6480464 Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of APLN mRNA], Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of APLN protein] CTD PMID:17878221 rotenone decreases expression ISO RGD:1351986 6480464 Rotenone results in decreased expression of APLN mRNA CTD PMID:32870474 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of APLN mRNA CTD PMID:28374803 silicon dioxide increases expression ISO RGD:1351986 6480464 Silicon Dioxide analog results in increased expression of APLN mRNA CTD PMID:25895662 silver atom decreases expression ISO RGD:1332289 6480464 Silver results in decreased expression of APLN mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:1332289 6480464 Silver results in decreased expression of APLN mRNA CTD PMID:27131904 sotorasib multiple interactions ISO RGD:1351986 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of APLN mRNA CTD PMID:36139627 Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of APLN mRNA CTD PMID:21515302 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in decreased expression of APLN mRNA] CTD PMID:20032058 Tetrachlorobisphenol A multiple interactions ISO RGD:1351986 6480464 tetrachlorodian results in increased expression of and results in increased secretion of APLN protein CTD PMID:28111160 Tetrachlorobisphenol A increases expression ISO RGD:1351986 6480464 tetrachlorodian results in increased expression of APLN mRNA CTD PMID:28111160 thalidomide decreases expression ISO RGD:1332289 6480464 Thalidomide results in decreased expression of APLN mRNA CTD PMID:26217789 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of APLN mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO RGD:1332289 6480464 titanium dioxide results in decreased expression of APLN mRNA CTD PMID:23557971 , PMID:27760801 titanium dioxide multiple interactions ISO RGD:1332289 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of APLN mRNA CTD PMID:29950665 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of APLN mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of APLN mRNA CTD PMID:25729387 trametinib multiple interactions ISO RGD:1351986 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of APLN mRNA CTD PMID:36139627 triclosan increases expression ISO RGD:1351986 6480464 Triclosan results in increased expression of APLN mRNA CTD PMID:30510588 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1351986 6480464 tris(2-butoxyethyl) phosphate affects the expression of APLN mRNA CTD PMID:29024780 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of APLN mRNA CTD PMID:21515302 valproic acid increases expression ISO RGD:1351986 6480464 Valproic Acid results in increased expression of APLN mRNA CTD PMID:28001369 vincaleukoblastine decreases expression EXP 6480464 Vinblastine results in decreased expression of APLN mRNA CTD PMID:20624997 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of APLN mRNA CTD PMID:19015723 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of APLN mRNA CTD PMID:22570695 vincristine decreases expression EXP 6480464 Vincristine results in decreased expression of APLN mRNA CTD PMID:20624997 zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of APLN mRNA CTD PMID:17557909 ziram increases expression ISO RGD:1351986 6480464 Ziram results in increased expression of APLN mRNA CTD PMID:32870474
