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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstp1
Name: glutathione S-transferase pi 1
Acc ID: CHEBI:64318
Term: ergotamine
Definition: A peptide ergot alkaloid that is dihydroergotamine in which a double bond replaces the single bond between positions 9 and 10.
Chemical ID: MESH:D004878
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstp1multiple interactionsISORGD:7322576480464CTDErgotamine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2, 4-dinitrobenzene-glutathione conjugate]

PMID:23769903
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.