Il13ra2 (interleukin 13 receptor subunit alpha 2) - Rat Genome Database

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Gene: Il13ra2 (interleukin 13 receptor subunit alpha 2) Rattus norvegicus
Analyze
Symbol: Il13ra2
Name: interleukin 13 receptor subunit alpha 2
RGD ID: 620838
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Involved in cellular response to mechanical stimulus. Predicted to localize to external side of plasma membrane and receptor complex. Used to study fatty liver disease. Human ortholog(s) of this gene implicated in breast cancer and pancreatic cancer. Orthologous to human IL13RA2 (interleukin 13 receptor subunit alpha 2); PARTICIPATES IN interleukin-4 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-13 receptor alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA-2; IL-13RA2; interleukin 13 receptor, alpha 2; interleukin-13 receptor alpha-2; interleukin-13 receptor subunit alpha-2; LOC100361488; rCG23169-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X111,002,590 - 111,074,053 (-)NCBI
Rnor_6.0 EnsemblX118,443,823 - 118,513,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X118,443,955 - 118,514,716 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X30,505,850 - 30,533,002 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X30,559,318 - 30,586,471 (-)NCBI
CeleraX110,307,396 - 110,375,950 (-)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Aspord C, etal., J Exp Med. 2007 May 14;204(5):1037-47. Epub 2007 Apr 16.
2. Chiba Y, etal., J Smooth Muscle Res. 2010;46(1):49-55.
3. Deepak P, etal., Int Immunol. 2010 Jan;22(1):53-63. doi: 10.1093/intimm/dxp114. Epub 2009 Nov 30.
4. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. GOA data from the GO Consortium
6. Hecker M, etal., Am J Respir Crit Care Med. 2010 Sep 15;182(6):805-18. Epub 2010 Jun 3.
7. Hussein YM, etal., J Investig Allergol Clin Immunol. 2011;21(2):101-7.
8. Jakubzick C, etal., Am J Pathol. 2004 Jun;164(6):1989-2001.
9. Kawakami K, etal., J Exp Med. 2001 Dec 17;194(12):1743-54.
10. Keane MP, etal., J Immunol. 2007 Jan 1;178(1):511-9.
11. Kioi M, etal., Int J Cancer. 2009 Mar 15;124(6):1440-8. doi: 10.1002/ijc.24067.
12. MGD data from the GO Consortium
13. Miyahara S, etal., J Allergy Clin Immunol. 2006 Nov;118(5):1110-6. Epub 2006 Aug 7.
14. NCBI rat LocusLink and RefSeq merged data July 26, 2002
15. Nishimura Y, etal., Circ J. 2008 Apr;72(4):647-53.
16. Pipeline to import KEGG annotations from KEGG into RGD
17. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
18. RGD automated data pipeline
19. RGD automated import pipeline for gene-chemical interactions
20. RGD comprehensive gene curation
21. Shimamura T, etal., J Immunol. 2008 Oct 1;181(7):4656-65.
22. Sivaprasad U, etal., J Immunol. 2010 Dec 1;185(11):6802-8. doi: 10.4049/jimmunol.1002118. Epub 2010 Oct 22.
23. Wilson MS, etal., J Clin Invest. 2007 Oct;117(10):2941-51.
24. Wu AH and Low WC, J Neurooncol 2002 Sep;59(2):99-105.
Additional References at PubMed
PMID:15632090   PMID:15944273   PMID:17429054  


Genomics

Comparative Map Data
Il13ra2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X111,002,590 - 111,074,053 (-)NCBI
Rnor_6.0 EnsemblX118,443,823 - 118,513,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X118,443,955 - 118,514,716 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X30,505,850 - 30,533,002 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X30,559,318 - 30,586,471 (-)NCBI
CeleraX110,307,396 - 110,375,950 (-)NCBICelera
Cytogenetic MapXq34NCBI
IL13RA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX115,003,975 - 115,019,977 (-)EnsemblGRCh38hg38GRCh38
GRCh38X115,003,982 - 115,017,616 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X114,238,545 - 114,252,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X114,144,794 - 114,158,463 (-)NCBINCBI36hg18NCBI36
Build 34X114,061,519 - 114,075,187NCBI
CeleraX114,673,713 - 114,687,382 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX103,824,475 - 103,837,544 (-)NCBIHuRef
CHM1_1X114,149,412 - 114,163,077 (-)NCBICHM1_1
Il13ra2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X146,166,474 - 146,214,982 (-)NCBIGRCm39mm39
GRCm39 EnsemblX146,166,472 - 146,212,188 (-)Ensembl
GRCm38X147,383,478 - 147,429,192 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX147,383,476 - 147,429,192 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X143,818,021 - 143,838,375 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X142,629,846 - 142,650,204 (-)NCBImm8
CeleraX131,321,061 - 131,341,527 (-)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX68.46NCBI
Il13ra2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955490709,446 - 758,272 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955490708,144 - 758,195 (+)NCBIChiLan1.0ChiLan1.0
IL13RA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X114,597,088 - 114,635,253 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX114,597,077 - 114,635,253 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X104,092,993 - 104,146,062 (-)NCBIMhudiblu_PPA_v0panPan3
IL13RA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X87,747,373 - 87,776,797 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX87,747,373 - 87,776,798 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX73,868,563 - 73,897,928 (-)NCBI
ROS_Cfam_1.0X89,462,267 - 89,540,412 (-)NCBI
UMICH_Zoey_3.1X86,906,747 - 86,936,111 (-)NCBI
UNSW_CanFamBas_1.0X88,581,088 - 88,610,454 (-)NCBI
UU_Cfam_GSD_1.0X88,414,159 - 88,443,524 (-)NCBI
Il13ra2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X86,774,105 - 86,816,943 (-)NCBI
SpeTri2.0NW_004936499860,179 - 883,884 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL13RA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX94,402,675 - 94,439,060 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X94,402,665 - 94,455,609 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X108,965,152 - 109,018,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL13RA2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X102,589,947 - 102,628,853 (-)NCBI
ChlSab1.1 EnsemblX102,590,045 - 102,603,260 (-)Ensembl
Il13ra2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624940825,368 - 842,268 (+)NCBI

Position Markers
D11Bhm88  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X118,515,032 - 118,515,126NCBIRnor6.0
Rnor_5.0X118,659,043 - 118,659,137UniSTSRnor5.0
RGSC_v3.4X30,830,187 - 30,830,281UniSTSRGSC3.4
RGSC_v3.4X30,478,134 - 30,478,228UniSTSRGSC3.4
CeleraX110,376,266 - 110,376,360UniSTS
Cytogenetic MapXq14UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X70352120127888215Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X82930791127930791Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X101333032146333032Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX107886746152409805Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X110957467155957467Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X110957467155957467Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:133
Count of miRNA genes:107
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000043338
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 18 17
Low 2 20 38 28 19 28 1 1 10 4 14 9 1
Below cutoff 1 20 19 13 13 7 8 52 11 7 2 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000043338   ⟹   ENSRNOP00000041564
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX118,444,474 - 118,513,061 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084465   ⟹   ENSRNOP00000069280
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX118,443,823 - 118,459,355 (-)Ensembl
RefSeq Acc Id: NM_133538   ⟹   NP_598222
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X111,002,594 - 111,074,053 (-)NCBI
Rnor_6.0X118,444,476 - 118,514,716 (-)NCBI
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBI
RGSC_v3.4X30,505,850 - 30,533,002 (-)RGD
CeleraX110,307,396 - 110,375,950 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257427   ⟹   XP_006257489
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X111,002,590 - 111,049,099 (-)NCBI
Rnor_6.0X118,443,955 - 118,490,738 (-)NCBI
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257428   ⟹   XP_006257490
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X118,443,955 - 118,488,326 (-)NCBI
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257430   ⟹   XP_006257492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X118,443,955 - 118,513,045 (-)NCBI
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257431   ⟹   XP_006257493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X118,443,955 - 118,466,799 (-)NCBI
Rnor_5.0X118,588,748 - 118,658,727 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773388   ⟹   XP_008771610
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X118,443,955 - 118,488,326 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773389   ⟹   XP_008771611
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X118,443,955 - 118,513,045 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773390   ⟹   XP_008771612
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X118,443,955 - 118,463,195 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099436   ⟹   XP_038955364
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X111,002,590 - 111,069,653 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_598222   ⟸   NM_133538
- Peptide Label: precursor
- UniProtKB: G3V9B6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257492   ⟸   XM_006257430
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006257489   ⟸   XM_006257427
- Peptide Label: isoform X1
- UniProtKB: G3V9B6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257490   ⟸   XM_006257428
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006257493   ⟸   XM_006257431
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771611   ⟸   XM_008773389
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771610   ⟸   XM_008773388
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771612   ⟸   XM_008773390
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000041564   ⟸   ENSRNOT00000043338
RefSeq Acc Id: ENSRNOP00000069280   ⟸   ENSRNOT00000084465
RefSeq Acc Id: XP_038955364   ⟸   XM_039099436
- Peptide Label: isoform X1
Protein Domains
Fibronectin type-III

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620838 AgrOrtholog
Ensembl Genes ENSRNOG00000032973 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041564 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000069280 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000043338 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000084465 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Short_hematopoietin_rcpt_2_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TypeI_recpt_CBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171060 UniProtKB/TrEMBL
NCBI Gene 171060 ENTREZGENE
Pfam IL6Ra-bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il13ra2 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMATOPO_REC_S_F2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3V9B6 ENTREZGENE, UniProtKB/TrEMBL
  I13R2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-16 Il13ra2  interleukin 13 receptor subunit alpha 2  Il13ra2  interleukin 13 receptor, alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Il13ra2  interleukin 13 receptor, alpha 2  LOC100361488  rCG23169-like  Data Merged 737654 PROVISIONAL
2010-05-05 LOC100361488  rCG23169-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Il13ra2  interleukin 13 receptor, alpha 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Il13ra2  interleukin 13 receptor, alpha 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains has a short cytoplasmic domain and an extracellular domain 633080
gene_expression expressed in the brain, spleen, liver, thymus, stomach, and testis 633080
gene_homology 91.2% and 54.2% homologous to mouse and human gene 633080