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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ionophore
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Accession:CHEBI:24869 term browser browse the term
Definition:A compound which can carry specific ions through membranes of cells or organelles.
Synonyms:related_synonym: ionophores
 xref: Wikipedia:Ionophore



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(S,S,S)-nicotianamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO nicotianamine results in decreased activity of ACE protein CTD PMID:26106051 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases activity ISO nicotianamine results in decreased activity of ACE2 protein CTD PMID:26106051 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
alborixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO alborixin results in increased expression of BAX protein CTD PMID:27378626 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO alborixin results in decreased expression of BCL2 protein CTD PMID:27378626 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 increases cleavage ISO alborixin results in increased cleavage of CASP3 protein CTD PMID:27378626 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO alborixin results in increased activity of CASP8 protein CTD PMID:27378626 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO alborixin results in increased activity of CASP9 protein CTD PMID:27378626 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO alborixin results in increased cleavage of PARP1 protein CTD PMID:27378626 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
bafilomycin A1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aim2 absent in melanoma 2 multiple interactions ISO [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of AIM2 protein CTD PMID:32645460 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]] CTD PMID:22689575 PMID:37914286 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Alb albumin decreases uptake ISO bafilomycin A1 results in decreased uptake of ALB protein CTD PMID:16313995 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bafilomycin A1 results in increased expression of APAF1 protein CTD PMID:28483490 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Arf6 ADP-ribosylation factor 6 multiple interactions EXP bafilomycin A1 inhibits the reaction [maduramicin results in decreased expression of ARF6 protein] CTD PMID:37394175 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] CTD PMID:16769263 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]
[bafilomycin A1 co-treated with Swainsonine] results in increased expression of ATG5 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of ATG5 protein
CTD PMID:29938581 PMID:36402259 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bafilomycin A1 inhibits the reaction [Hydroxychloroquine results in increased activity of BAX protein] CTD PMID:12813466 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
bafilomycin A1 results in decreased expression of BCL2 mRNA
bafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]
CTD PMID:31310755 PMID:34374793 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO
EXP
bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein]
[Swainsonine co-treated with bafilomycin A1] results in increased expression of BECN1 protein; bafilomycin A1 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BECN1 protein]
bafilomycin A1 results in increased expression of BECN1 protein
CTD PMID:32645460 PMID:33186601 PMID:33242459 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:23111315 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
increases expression
EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]
vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein]
bafilomycin A1 results in increased expression of BID protein modified form
CTD PMID:26853465 PMID:28378122 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of BNIP3 mRNA; bafilomycin A1 results in increased expression of BNIP3 protein
BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; capivasertib affects the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; Lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; vistusertib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]
CTD PMID:25981168 PMID:26853465 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Casp3 caspase 3 decreases activity
increases cleavage
multiple interactions
increases activity
ISO
EXP
bafilomycin A1 results in decreased activity of CASP3 protein
bafilomycin A1 results in increased cleavage of CASP3 protein
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]
bafilomycin A1 results in increased activity of CASP3 protein
[Swainsonine co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]
[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; [bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein]
CTD PMID:20876807 PMID:23380477 PMID:24321340 PMID:24889822 PMID:25266202 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases activity ISO bafilomycin A1 results in increased activity of CASP4 protein CTD PMID:20371669 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 increases activity
decreases activity
ISO bafilomycin A1 results in increased activity of CASP7 protein
bafilomycin A1 results in decreased activity of CASP7 protein
CTD PMID:20371669 PMID:25981168 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]
CTD PMID:28378122 PMID:29111403 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP9 protein]
CTD PMID:28378122 PMID:30240709 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of CCND1 protein] CTD PMID:33359579 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO bafilomycin A1 inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] CTD PMID:29074359 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased expression of CDH1 protein] CTD PMID:36044967 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO bafilomycin A1 inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein] CTD PMID:36044967 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Ctsb cathepsin B multiple interactions ISO bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]; bafilomycin A1 inhibits the reaction [Hydroxychloroquine affects the localization of CTSB protein] CTD PMID:12813466 PMID:23380477 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D decreases cleavage ISO bafilomycin A1 results in decreased cleavage of CTSD protein CTD PMID:36070022 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsl cathepsin L decreases cleavage ISO bafilomycin A1 results in decreased cleavage of CTSL protein CTD PMID:36070022 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO bafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:26682054 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
EXP bafilomycin A1 results in increased expression of DDIT4 protein
[EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein
CTD PMID:22689575 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions EXP bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]] CTD PMID:37914286 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Aspartic Acid; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Taurine; [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein; bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine] CTD PMID:22689575 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:22689575 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Epor erythropoietin receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Aristolochic Acids results in increased degradation of and results in decreased expression of EPOR protein] CTD PMID:26136230 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:20200208 PMID:28378122 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] CTD PMID:29371327 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased acetylation of FOXO1 protein]] CTD PMID:24889822 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTH1 protein] CTD PMID:37951334 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTL protein] CTD PMID:37951334 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO bafilomycin A1 results in increased expression of GJA1 protein CTD PMID:35750204 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of HIF1A protein
HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]
CTD PMID:25981168 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of HMOX1 protein
[bafilomycin A1 co-treated with methanandamide] results in increased expression of HMOX1 protein; [bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; bafilomycin A1 inhibits the reaction [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of HMOX1 protein]
CTD PMID:29796178 PMID:33076330 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma decreases expression ISO bafilomycin A1 results in decreased expression of IFNG mRNA CTD PMID:16932910 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of IL1B mRNA
[bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]
CTD PMID:16932910 PMID:24158569 PMID:32645460 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO bafilomycin A1 results in increased expression of IL6 mRNA CTD PMID:16932910 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] CTD PMID:32283200 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ins2 insulin 2 multiple interactions EXP bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22689575 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions
increases expression
ISO [bafilomycin A1 co-treated with Swainsonine] results in increased expression of LAMP1 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased expression of LAMP1 protein
bafilomycin A1 results in increased expression of LAMP1 protein
CTD PMID:36402259 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] CTD PMID:32278738 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 increases response to substance ISO LRRK2 gene mutant form results in increased susceptibility to bafilomycin A1 CTD PMID:25017139 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Swainsonine results in decreased expression of MAN2A1 mRNA] CTD PMID:36402259 NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Swainsonine results in decreased expression of MAN2B1 mRNA] CTD PMID:36402259 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
increases expression
ISO
EXP
bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein]
bafilomycin A1 inhibits the reaction [Lidocaine results in increased expression of MAP1LC3A protein]
bafilomycin A1 results in increased expression of MAP1LC3A protein modified form
CTD PMID:30871063 PMID:31120128 PMID:37914286 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
increases expression
increases cleavage
decreases degradation
ISO
EXP
[bafilomycin A1 co-treated with Miconazole] results in increased expression of MAP1LC3B protein; [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [[alpha-Chlorohydrin co-treated with Diosgenin] results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [metarrestin results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Miconazole results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ovatodiolide results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [Sevoflurane results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 results in increased expression of and results in increased lipidation of MAP1LC3B protein; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
bafilomycin A1 results in increased lipidation of MAP1LC3B protein
[Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 inhibits the reaction [olaparib inhibits the reaction [Hydrogen Peroxide results in increased lipidation of MAP1LC3B protein]]; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form]
bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
[bafilomycin A1 co-treated with Swainsonine] results in increased expression of MAP1LC3B mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [tricalcium phosphate results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein]
bafilomycin A1 results in increased cleavage of MAP1LC3B protein
bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form
bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
CTD PMID:23880069 PMID:24145604 PMID:25301941 PMID:26459185 PMID:26853465 More... NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK1 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein]
bafilomycin A1 results in increased expression of MAPK1 protein modified form
CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK3 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK3 protein]
bafilomycin A1 results in increased expression of MAPK3 protein modified form
CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog multiple interactions EXP bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]] CTD PMID:37914286 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
ISO
EXP
bafilomycin A1 results in decreased phosphorylation of MTOR protein
bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]
CTD PMID:31310755 PMID:37914286 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO bafilomycin A1 results in increased expression of MTTP protein CTD PMID:34516972 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of NCOA4 protein] CTD PMID:37951334 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] CTD PMID:24532803 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[Particulate Matter co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [[Silicon Dioxide co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Silicon Dioxide results in increased expression of NFE2L2 protein]
bafilomycin A1 results in increased expression of NFE2L2 protein
CTD PMID:30698894 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of NLRP3 protein
bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein]
CTD PMID:32645460 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO bafilomycin A1 results in decreased expression of NR5A1 protein CTD PMID:29524503 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
ISO
EXP
[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]
bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]
bafilomycin A1 results in increased expression of PARP1 protein modified form
CTD PMID:20876807 PMID:21616090 PMID:24321340 PMID:25981168 PMID:28063998 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of PCNA mRNA] CTD PMID:33359579 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [Lidocaine results in increased expression of PINK1 protein] CTD PMID:37914286 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO
EXP
bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of PRKAA1 protein]
bafilomycin A1 inhibits the reaction [Lidocaine results in increased phosphorylation of PRKAA1 protein]
CTD PMID:37481222 PMID:37914286 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of PRKAA2 protein] CTD PMID:37481222 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkd2 protein kinase D2 multiple interactions ISO [PRKD2 protein affects the susceptibility to [erastin co-treated with bafilomycin A1]] which affects the abundance of Malondialdehyde; bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTH1 protein]; bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of FTL protein]; bafilomycin A1 affects the reaction [[PRKD2 protein affects the susceptibility to erastin] which affects the expression of NCOA4 protein]; PRKD2 protein affects the susceptibility to [erastin co-treated with bafilomycin A1] CTD PMID:37951334 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO bafilomycin A1 affects the localization of and results in increased activity of RELA protein CTD PMID:10339586 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
ISO
EXP
bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein
bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:22689575 PMID:31310755 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]] CTD PMID:37914286 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]] CTD PMID:24889822 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents]; bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Zinc]; bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc30a3 solute carrier family 30 member 3 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein]
bafilomycin A1 results in increased expression of SNAI1 protein
CTD PMID:32645460 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snca synuclein alpha multiple interactions
increases expression
ISO [bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein
bafilomycin A1 results in increased expression of SNCA protein
CTD PMID:26031332 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sort1 sortilin 1 decreases expression ISO bafilomycin A1 results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
bafilomycin A1 results in increased expression of SQSTM1 protein
bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]
[Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [metarrestin results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [Miconazole results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]]; Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
[bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein; [bafilomycin A1 co-treated with Swainsonine] results in increased expression of SQSTM1 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of SQSTM1 protein; bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; decamethrin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
CTD PMID:21778691 PMID:21858812 PMID:23151917 PMID:24145604 PMID:24238063 More... NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO bafilomycin A1 inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of STK11 protein] CTD PMID:37481222 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tlr8 toll-like receptor 8 multiple interactions ISO bafilomycin A1 inhibits the reaction [resiquimod results in increased activity of TLR8 protein] CTD PMID:21398612 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TNF mRNA
[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
CTD PMID:16932910 PMID:24145604 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TOMM20 protein
Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein]
CTD PMID:30209975 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein] CTD PMID:23380477 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions EXP bafilomycin A1 affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide affects the reaction [Glucose affects the phosphorylation of ULK1 protein]] CTD PMID:29128638 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Usp8 ubiquitin specific peptidase 8 multiple interactions ISO [Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased cleavage of PARP1 protein] CTD PMID:35022897 NCBI chr 3:113,962,136...114,009,683
Ensembl chr 3:113,962,164...114,009,666
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions
increases expression
ISO Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] CTD PMID:30209975 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein CTD PMID:30698894 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein]
bafilomycin A1 results in increased expression of VIM protein
CTD PMID:32645460 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
beauvericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor decreases expression ISO beauvericin results in decreased expression of AATF mRNA CTD PMID:29203277 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA CTD PMID:31100301 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases expression ISO beauvericin results in decreased expression of ACIN1 mRNA CTD PMID:29203277 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Actb actin, beta decreases expression ISO beauvericin results in decreased expression of ACTB mRNA CTD PMID:29203277 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO beauvericin results in decreased expression of AEN mRNA CTD PMID:29203277 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO beauvericin results in decreased expression of AIFM1 mRNA CTD PMID:29203277 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO beauvericin results in decreased expression of ALDOA mRNA CTD PMID:29203277 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 8:103,205,520...103,213,936
Ensembl chr 8:103,205,520...103,213,936
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO beauvericin results in decreased expression of APRT mRNA CTD PMID:29203277 NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Ar androgen receptor multiple interactions ISO beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:30716354 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO beauvericin results in decreased expression of ARHGDIA mRNA CTD PMID:29203277 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO beauvericin results in increased expression of ARPP21 mRNA CTD PMID:29203277 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO beauvericin results in decreased expression of BAX mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BAX mRNA
CTD PMID:29203277 PMID:32956828 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO beauvericin results in increased expression of BCL2 mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BCL2 mRNA
CTD PMID:29203277 PMID:32956828 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO beauvericin results in increased expression of BIRC2 mRNA CTD PMID:29203277 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO beauvericin results in increased expression of BIRC3 mRNA CTD PMID:29203277 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Btf3l4 basic transcription factor 3-like 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 5:123,567,902...123,587,527
Ensembl chr 5:123,567,907...123,586,866
JBrowse link
G C1qtnf3 C1q and TNF related 3 decreases expression ISO beauvericin results in decreased expression of C1QTNF3 mRNA CTD PMID:29203277 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
JBrowse link
G C1qtnf6 C1q and TNF related 6 increases expression ISO beauvericin results in increased expression of C1QTNF6 mRNA CTD PMID:29203277 NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CAAP1 mRNA CTD PMID:29203277 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO beauvericin results in decreased expression of CARD11 mRNA CTD PMID:29203277 NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP
ISO
beauvericin results in increased activity of CASP3 protein
[zearalenol co-treated with beauvericin] results in increased expression of CASP3 mRNA
CTD PMID:25178661 PMID:32956828 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity EXP beauvericin results in increased activity of CASP7 protein CTD PMID:25178661 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression ISO beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression ISO beauvericin results in increased expression of CASP9 mRNA CTD PMID:29203277 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 decreases expression ISO beauvericin results in decreased expression of CCAR2 mRNA CTD PMID:29203277 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
G Ccdc124 coiled-coil domain containing 124 decreases expression ISO beauvericin results in decreased expression of CCDC124 mRNA CTD PMID:29203277 NCBI chr16:18,566,745...18,572,564
Ensembl chr16:18,566,745...18,572,564
JBrowse link
G Ccdc180 coiled-coil domain containing 180 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO beauvericin results in decreased expression of CCDC86 mRNA CTD PMID:29203277 NCBI chr 1:207,590,167...207,596,547
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd81 Cd81 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 decreases expression ISO beauvericin results in decreased expression of CDK2AP2 mRNA CTD PMID:29203277 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beauvericin results in increased expression of CFLAR mRNA CTD PMID:29203277 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 decreases expression ISO beauvericin results in decreased expression of CHCHD2 mRNA CTD PMID:29203277 NCBI chr12:26,828,738...26,834,762
Ensembl chr12:26,828,736...26,834,755
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CIAPIN1 mRNA CTD PMID:29203277 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr19:54,395,746...54,398,348
Ensembl chr19:54,395,742...54,399,407
JBrowse link
G Coro1c coronin 1C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO beauvericin results in decreased expression of COTL1 mRNA CTD PMID:29203277 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508
JBrowse link
G Cpne1 copine 1 decreases expression ISO beauvericin results in decreased expression of CPNE1 mRNA CTD PMID:29203277 NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
JBrowse link
G Csdc2 cold shock domain containing C2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
JBrowse link
G Csk C-terminal Src kinase decreases expression ISO beauvericin results in decreased expression of CSK mRNA CTD PMID:29203277 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO beauvericin results in decreased expression of DDIAS mRNA CTD PMID:29203277 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
JBrowse link
G Ddx47 DEAD-box helicase 47 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO beauvericin results in increased expression of EDEM1 mRNA CTD PMID:29203277 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO beauvericin results in decreased expression of EIF5A mRNA CTD PMID:29203277 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beauvericin results in increased expression of FAIM2 mRNA CTD PMID:29203277 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Gaa alpha glucosidase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gna14 G protein subunit alpha 14 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Golga1 golgin A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 3:22,765,690...22,812,637
Ensembl chr 3:22,767,761...22,812,585
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr18 G protein-coupled receptor 18 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 2:183,780,583...183,783,030 JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA CTD PMID:31100301 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Immt inner membrane mitochondrial protein multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Klf12 KLF transcription factor 12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt16 keratin 16 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt27 keratin 27 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr10:84,298,684...84,303,967
Ensembl chr10:84,298,508...84,303,967
JBrowse link
G Krt5 keratin 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Krt76 keratin 76 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lat linker for activation of T cells decreases expression ISO beauvericin results in decreased expression of LAT mRNA CTD PMID:29203277 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK1 protein CTD PMID:25178661 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK3 protein CTD PMID:25178661 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Matn4 matrilin 4 decreases expression ISO beauvericin results in decreased expression of MATN4 mRNA CTD PMID:29203277 NCBI chr 3:153,120,605...153,135,628
Ensembl chr 3:153,120,632...153,135,865
JBrowse link
G Mavs mitochondrial antiviral signaling protein increases expression ISO beauvericin results in increased expression of MAVS mRNA CTD PMID:29203277 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Med6 mediator complex subunit 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr 6:101,270,410...101,283,929
Ensembl chr 6:101,270,410...101,283,876
JBrowse link
G Moap1 modulator of apoptosis 1 increases expression ISO beauvericin results in increased expression of MOAP1 mRNA CTD PMID:29203277 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 decreases expression ISO beauvericin results in decreased expression of MRPL4 mRNA CTD PMID:29203277 NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA; [beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX1 mRNA; [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA
beauvericin results in decreased expression of COX1 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression
multiple interactions
ISO beauvericin results in decreased expression of COX3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO beauvericin results in decreased expression of CYTB mRNA CTD PMID:29203277 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND2 mRNA
beauvericin results in increased expression of ND2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND3 mRNA
beauvericin results in increased expression of ND3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND4L mRNA
beauvericin results in increased expression of ND4L mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND4L mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4L mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND5 mRNA
beauvericin results in increased expression of ND5 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND5 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND5 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND6 mRNA
CTD PMID:34015425 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mtrf1l mitochondrial translation release factor 1 like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr 1:42,208,553...42,221,020
Ensembl chr 1:42,210,583...42,220,836
JBrowse link
G Myo18a myosin XVIIIa increases expression ISO beauvericin results in increased expression of MYO18A mRNA CTD PMID:29203277 NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr 1:151,300,446...151,412,086
Ensembl chr 1:151,300,467...151,413,521
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A increases expression ISO beauvericin results in increased expression of NLRP1 mRNA CTD PMID:29203277 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 increases expression ISO beauvericin results in increased expression of NOD1 mRNA CTD PMID:29203277 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nol3 nucleolar protein 3 increases expression ISO beauvericin results in increased expression of NOL3 mRNA CTD PMID:29203277 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
JBrowse link
G Oga O-GlcNAcase increases expression ISO beauvericin results in increased expression of OGA mRNA CTD PMID:29203277 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression ISO beauvericin results in increased expression of OGT mRNA CTD PMID:29203277 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions
increases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of OSGIN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of OSGIN1 mRNA
beauvericin results in increased expression of OSGIN1 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
JBrowse link
G Parvg parvin, gamma multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr 7:115,456,183...115,475,707
Ensembl chr 7:115,456,209...115,475,104
JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO beauvericin results in decreased expression of PAWR mRNA CTD PMID:29203277 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO beauvericin results in decreased expression of PDCD11 mRNA CTD PMID:29203277 NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999
JBrowse link
G Pdcd2 programmed cell death 2 decreases expression ISO beauvericin results in decreased expression of PDCD2 mRNA CTD PMID:29203277 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
JBrowse link
G Pdcd2l programmed cell death 2-like increases expression ISO beauvericin results in increased expression of PDCD2L mRNA CTD PMID:29203277 NCBI chr 1:86,810,292...86,822,554
Ensembl chr 1:86,810,292...86,822,554
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO beauvericin results in decreased expression of PDCD4 mRNA CTD PMID:29203277 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pdcd5 programmed cell death 5 increases expression ISO beauvericin results in increased expression of PDCD5 mRNA CTD PMID:29203277 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein increases expression ISO beauvericin results in increased expression of PDCD6IP mRNA CTD PMID:29203277 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO beauvericin results in decreased expression of PDIA4 mRNA CTD PMID:29203277 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pfn1 profilin 1 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of PFN1 mRNA
[beauvericin co-treated with enniatins] results in increased expression of PFN1 protein
CTD PMID:29203277 PMID:32407736 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466
JBrowse link
G Pidd1 p53-induced death domain protein 1 decreases expression ISO beauvericin results in decreased expression of PIDD1 mRNA CTD PMID:29203277 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO beauvericin results in decreased expression of PLK1 mRNA CTD PMID:29203277 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pls3 plastin 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
JBrowse link
G Ppan peter pan homolog decreases expression ISO beauvericin results in decreased expression of PPAN mRNA CTD PMID:29203277 NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
JBrowse link
G Ppib peptidylprolyl isomerase B decreases expression ISO beauvericin results in decreased expression of PPIB mRNA CTD PMID:29203277 NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression ISO beauvericin results in decreased expression of PPP1R14B mRNA CTD PMID:29203277 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psme4 proteasome activator subunit 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Relt RELT, TNF receptor decreases expression ISO beauvericin results in decreased expression of RELT mRNA CTD PMID:29203277 NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196
JBrowse link
G Rp2 RP2 activator of ARL3 GTPase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:1,872,582...1,916,704
Ensembl chr  X:1,873,306...1,916,688
JBrowse link
G Rpl37a ribosomal protein L37A multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rpl5 ribosomal protein L5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Scml2 Scm polycomb group protein like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:33,523,179...33,677,672
Ensembl chr  X:33,524,530...33,652,742
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
JBrowse link
G Sdr42e2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr 1:175,361,630...175,382,769
Ensembl chr 1:175,362,150...175,382,050
JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression ISO beauvericin results in decreased expression of SEC13 mRNA CTD PMID:29203277 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO beauvericin results in decreased expression of SIVA1 mRNA CTD PMID:29203277 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases activity EXP beauvericin results in decreased activity of SRC protein CTD PMID:25178661 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srm spermidine synthase decreases expression ISO beauvericin results in decreased expression of SRM mRNA CTD PMID:29203277 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of SRXN1 mRNA
beauvericin results in decreased expression of SRXN1 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Tbc1d2b TBC1 domain family, member 2B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr 8:90,746,220...90,814,867
Ensembl chr 8:90,746,233...90,814,832
JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
JBrowse link
G Tcp11l1 t-complex 11 like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr 3:91,047,006...91,092,687
Ensembl chr 3:90,998,270...91,092,006
JBrowse link
G Tcp11l2 t-complex 11 like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095
JBrowse link
G Thyn1 thymocyte nuclear protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr 8:25,406,563...25,415,445
Ensembl chr 8:25,406,500...25,415,445
JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr 6:89,610,094...89,622,924
Ensembl chr 6:89,610,094...89,622,924
JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tmem263 transmembrane protein 263 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr 7:18,610,151...18,628,311
Ensembl chr 7:18,610,149...18,628,534
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO beauvericin results in decreased expression of TNFSF10 mRNA CTD PMID:29203277 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Tubb4a tubulin, beta 4A class IVa multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB protein CTD PMID:32407736 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
decreases expression
ISO beauvericin results in increased expression of TXNIP mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of TXNIP mRNA
beauvericin results in decreased expression of TXNIP mRNA
CTD PMID:29203277 PMID:34015425 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of UCP2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of UCP2 mRNA
beauvericin results in decreased expression of UCP2 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ybx1 Y box binding protein 1 decreases expression ISO beauvericin results in decreased expression of YBX1 mRNA CTD PMID:29203277 NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Ybx3 Y box binding protein 3 decreases expression ISO beauvericin results in decreased expression of YBX3 mRNA CTD PMID:29203277 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
G Ykt6 YKT6 v-SNARE homolog multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385
JBrowse link
carbonyl cyanide p-trifluoromethoxyphenylhydrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18854758 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] CTD PMID:28798983 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BAX mRNA CTD PMID:16039398 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BCL2L1 mRNA CTD PMID:16039398 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 increases activity ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased activity of CASP3 protein CTD PMID:20683024 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CASP8 mRNA CTD PMID:16039398 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CAT mRNA CTD PMID:16039398 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnc cyclin C decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNC mRNA CTD PMID:16039398 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCND1 mRNA CTD PMID:16039398 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccng1 cyclin G1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNG1 mRNA CTD PMID:16039398 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] CTD PMID:19819288 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein]
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CDKN1B protein
CTD PMID:19819288 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein
[Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate
CTD PMID:14975680 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coq10a coenzyme Q10A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ10A protein CTD PMID:21308897 NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ2 mRNA CTD PMID:21308897 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ3 mRNA CTD PMID:21308897 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Coq4 coenzyme Q4 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ4 mRNA CTD PMID:21308897 NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799
JBrowse link
G Coq5 coenzyme Q5, methyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ5 mRNA CTD PMID:21308897 NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848
JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ6 mRNA CTD PMID:21308897 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657
JBrowse link
G Coq7 coenzyme Q7, hydroxylase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ7 mRNA CTD PMID:21308897 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
JBrowse link
G Coq8a coenzyme Q8A increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ8A mRNA CTD PMID:21308897 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
JBrowse link
G Coq9 coenzyme Q9 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ9 mRNA CTD PMID:21308897 NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CYP1A1 mRNA CTD PMID:16039398 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DDB1 mRNA CTD PMID:16039398 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DNAJA1 mRNA CTD PMID:16039398 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Egr1 early growth response 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EGR1 mRNA CTD PMID:16039398 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EPHX2 mRNA CTD PMID:16039398 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides] CTD PMID:27385396 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GADD45A mRNA CTD PMID:16039398 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA CTD PMID:16039398 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSR mRNA CTD PMID:16039398 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA CTD PMID:16039398 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HMOX1 mRNA CTD PMID:16039398 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HMOX2 mRNA CTD PMID:16039398 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hsf1 heat shock transcription factor 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSF1 mRNA CTD PMID:16039398 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSP90AA1 mRNA CTD PMID:16039398 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1A mRNA CTD PMID:16039398 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1B mRNA CTD PMID:16039398 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1L mRNA CTD PMID:16039398 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA2 mRNA CTD PMID:16039398 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA4 mRNA CTD PMID:16039398 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA8 mRNA CTD PMID:16039398 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HSPE1 mRNA CTD PMID:16039398 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of ICAM1 mRNA CTD PMID:17416599 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il18 interleukin 18 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA CTD PMID:16039398 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA CTD PMID:16039398 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ4 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA CTD PMID:16039398 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT1A mRNA CTD PMID:16039398 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT2A mRNA CTD PMID:16039398 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NFKBIA mRNA CTD PMID:16039398 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nipa1 NIPA magnesium transporter 1 decreases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NIPA1 mRNA CTD PMID:27157538 NCBI chr 1:106,834,000...106,875,148
Ensembl chr 1:106,834,000...106,874,790
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of PDSS1 mRNA CTD PMID:21308897 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PDSS2 mRNA CTD PMID:21308897 NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
affects localization
ISO PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PTGS2 mRNA CTD PMID:16039398 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RAD23A mRNA CTD PMID:16039398 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
JBrowse link
G Rpl13a ribosomal protein L13A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RPL13A mRNA CTD PMID:16039398 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNA CTD PMID:16039398 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin] CTD PMID:1438304 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc41a2 solute carrier family 41 member 2 increases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SLC41A2 mRNA CTD PMID:27157538 NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SOD2 mRNA CTD PMID:16039398 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects response to substance ISO STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone CTD PMID:20224768 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of XRCC5 mRNA CTD PMID:16039398 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
CCCP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:12130563 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein] CTD PMID:24879156 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation
ISO ATM protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of ATM protein
CTD PMID:29660402 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Becn1 beclin 1 multiple interactions ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
CTD PMID:24879156 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases phosphorylation
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of BNIP3L protein
BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein]
CTD PMID:32142837 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Canx calnexin affects localization ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of CANX protein CTD PMID:28940366 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein] CTD PMID:33524445 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
EXP
ISO
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased cleavage of CASP3 protein]
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]
CTD PMID:24658017 PMID:29241732 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form]
CTD PMID:29241732 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of CIRBP mRNA CTD PMID:15075239 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4I1 protein CTD PMID:27318970 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Ctsl cathepsin L increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CTSL mRNA CTD PMID:15978749 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
ISO DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of DNM1L protein modified form
CTD PMID:28940366 PMID:29241732 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Eva1a eva-1 homolog A, regulator of programmed cell death multiple interactions ISO [1-Methyl-4-phenylpyridinium co-treated with Carbonyl Cyanide m-Chlorophenyl Hydrazone] results in increased localization of EVA1A protein CTD PMID:36078115 NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011
JBrowse link
G Faslg Fas ligand multiple interactions EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of FASLG mRNA] CTD PMID:24658017 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein] CTD PMID:30734931 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein
bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein]
CTD PMID:29371327 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] CTD PMID:34481905 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein
BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein]
CTD PMID:32142837 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA] CTD PMID:33524445 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30715550 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA protein] CTD PMID:34481905 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lep leptin multiple interactions
decreases response to substance
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased susceptibility to LEP protein
CTD PMID:11342529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of LONP1 mRNA CTD PMID:28940366 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Mapt microtubule-associated protein tau affects localization EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of MAPT protein CTD PMID:17634376 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mfn2 mitofusin 2 multiple interactions EXP
ISO
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and affects the localization of MFN2 protein
CTD PMID:24879156 PMID:28940366 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein
Deoxyglucose inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein]
CTD PMID:34481905 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:30715550 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of NFKB1 protein CTD PMID:15978749 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbib NFKB inhibitor beta decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of NFKBIB protein CTD PMID:15978749 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of OPA1 protein alternative form CTD PMID:28940366 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] CTD PMID:22872702 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pgam5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase multiple interactions ISO PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form] CTD PMID:29241732 NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein] CTD PMID:24879156 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions
affects localization
increases expression
increases stability
ISO
EXP
PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and results in increased phosphorylation of PINK1 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of PINK1 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased stability of PINK1 protein
CTD PMID:22872702 PMID:24879156 PMID:26070385 PMID:27318970 PMID:28673964 More... NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] CTD PMID:34481905 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase affects localization
increases response to substance
decreases response to substance
affects expression
decreases expression
increases phosphorylation
multiple interactions
ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein
PRKN gene mutant form results in increased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone
PRKN protein results in decreased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of PRKN protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Acetylcysteine inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein]; Tretinoin affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form]
CTD PMID:16517603 PMID:22872702 PMID:24879156 PMID:26070385 PMID:28673964 More... NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 protein]
CTD PMID:14514642 PMID:16024921 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rbm3 RNA binding motif protein 3 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of RBM3 mRNA CTD PMID:15075239 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of REL protein CTD PMID:15978749 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein] CTD PMID:33524445 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC2A1 protein] CTD PMID:34481905 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30715550 PMID:34481905 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of TIMM23 protein CTD PMID:29371327 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of TNF mRNA]
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]
CTD PMID:24658017 PMID:33524445 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
chlortetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity ISO Chlortetracycline results in decreased activity of CAT protein CTD PMID:30768968 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Chlortetracycline inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
desferrioxamine B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
increases expression
multiple interactions
EXP
ISO
Deferoxamine results in increased activity of ACO1 protein
Deferoxamine results in increased expression of ACO1 protein
[Deferoxamine results in decreased abundance of Iron] which results in increased activity of ACO1 protein
CTD PMID:10397746 PMID:11054110 PMID:15893546 PMID:16568477 PMID:18073202 More... NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 decreases expression EXP Deferoxamine results in decreased expression of ACO2 protein CTD PMID:16568477 PMID:17469137 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases activity
multiple interactions
ISO Deferoxamine results in decreased activity of ACP5 protein
Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein]
CTD PMID:31238089 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA] CTD PMID:36843388 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
increases expression
multiple interactions
EXP
ISO
Deferoxamine results in decreased expression of ACTA2 protein
Deferoxamine results in increased expression of ACTA2 mRNA
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA]
CTD PMID:18032466 PMID:30551460 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adm adrenomedullin increases expression ISO Deferoxamine results in increased expression of ADM mRNA CTD PMID:11754965 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of AKT1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of AKT1 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of AKT1 mRNA]
CTD PMID:18032466 PMID:34577062 PMID:35690295 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ALDH3A1 mRNA
Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]
CTD PMID:14645679 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ALPL mRNA
Indomethacin promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]; Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]
CTD PMID:16772336 PMID:21882223 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Anxa3 annexin A3 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein]
Deferoxamine results in decreased expression of ANXA3 protein
CTD PMID:19515424 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA] CTD PMID:33962019 PMID:35690295 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G App amyloid beta precursor protein affects binding
multiple interactions
ISO Deferoxamine binds to APP 5' UTR
[Deferoxamine binds to APP 5' UTR] which results in decreased expression of APP protein; [Deferoxamine binds to APP 5' UTR] which results in decreased secretion of APP protein modified form; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]
CTD PMID:15681799 PMID:17964426 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP Deferoxamine inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein] CTD PMID:20648640 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ARHGDIA protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein]
CTD PMID:19515424 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases activity
multiple interactions
increases expression
EXP
ISO
Deferoxamine results in increased activity of ARNT protein
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of ARNT mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of ARNT mRNA]
Deferoxamine results in increased expression of ARNT mRNA
CTD PMID:10559391 PMID:33962019 PMID:35690295 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Ash2l ASH2 like histone lysine methyltransferase complex subunit increases expression
affects expression
ISO Deferoxamine results in increased expression of ASH2L mRNA
Deferoxamine affects the expression of ASH2L mRNA
CTD PMID:23483119 NCBI chr16:66,242,205...66,264,064
Ensembl chr16:66,242,212...66,264,061
JBrowse link
G Atf1 activating transcription factor 1 increases activity EXP Deferoxamine results in increased activity of ATF1 protein CTD PMID:10559391 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Deferoxamine results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions
affects expression
ISO Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA] CTD PMID:31238089 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Atp7a ATPase copper transporting alpha increases expression
multiple interactions
EXP Deferoxamine results in increased expression of ATP7A mRNA
cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
CTD PMID:23174565 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA] CTD PMID:33962019 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of BAX mRNA; Deferoxamine results in increased expression of BAX protein
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BAX mRNA]
[Cisplatin co-treated with Deferoxamine] results in increased expression of BAX protein; [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of BAX protein; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA]; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA]; TP53 protein affects the reaction [Deferoxamine results in increased expression of BAX protein]
CTD PMID:16800926 PMID:21742779 PMID:33962019 PMID:34126102 PMID:34577062 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BBC3 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA]
CTD PMID:33962019 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased expression of BCL2 mRNA]; Deferoxamine inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA]
Deferoxamine results in decreased expression of BCL2 mRNA
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in decreased expression of BCL2 mRNA; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in decreased expression of BCL2 mRNA]
CTD PMID:30431687 PMID:33962019 PMID:34577062 PMID:35690295 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l15 Bcl2-like 15 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BCL2L15 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA]
CTD PMID:33962019 NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BDNF protein] CTD PMID:34577062 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BECN1 protein] CTD PMID:21742779 PMID:32687844 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA] CTD PMID:33962019 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]
Deferoxamine results in decreased expression of BMP6 mRNA
CTD PMID:25633564 PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BNIP3 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA]
CTD PMID:33962019 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BNIP3L mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA]
CTD PMID:11832486 PMID:33962019 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G C5 complement C5 multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Deferoxamine inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP Deferoxamine results in increased expression of CACNA1H mRNA CTD PMID:12679337 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression ISO Deferoxamine results in decreased expression of CAR2 mRNA CTD PMID:31238089 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car9 carbonic anhydrase 9 increases expression ISO Deferoxamine results in increased expression of CA9 mRNA CTD PMID:25351418 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:23764342 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
ISO
EXP
Deferoxamine results in increased expression of CASP3 protein
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
Deferoxamine results in increased activity of CASP3 protein
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA]; Deferoxamine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]
Deferoxamine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP3 mRNA]; Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Deferoxamine inhibits the reaction [Manganese results in increased activity of CASP3 protein]
CTD PMID:11933051 PMID:12523938 PMID:16374551 PMID:16800926 PMID:23764342 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO Deferoxamine results in increased activity of CASP8 protein
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]
CTD PMID:16374551 PMID:33962019 PMID:35690295 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein] CTD PMID:12540492 PMID:14766669 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP
ISO
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased activity of CAT protein]; Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CAT mRNA
CTD PMID:22115772 PMID:34577062 PMID:35690295 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 increases expression ISO Deferoxamine results in increased expression of CAV1 protein CTD PMID:16927372 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP Deferoxamine inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein] CTD PMID:25813056 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Deferoxamine results in decreased expression of CCNA2 protein CTD PMID:11468187 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Deferoxamine results in decreased expression of CCNB1 protein CTD PMID:11468187 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Deferoxamine results in decreased expression of CCND1 protein CTD PMID:11468187 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO Deferoxamine results in decreased expression of CCND2 protein CTD PMID:11468187 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Deferoxamine results in decreased expression of CCND3 protein CTD PMID:11468187 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 increases expression ISO Deferoxamine results in increased expression of CCNE1 protein CTD PMID:11468187 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Deferoxamine results in decreased expression of CD36 protein CTD PMID:24170104 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cdc14a cell division cycle 14A increases expression ISO Deferoxamine results in increased expression of CDC14A mRNA alternative form CTD PMID:16760464 NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity
decreases expression
ISO Deferoxamine results in decreased activity of CDK2 protein
Deferoxamine results in decreased expression of CDK2 protein
CTD PMID:11468187 PMID:17631934 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
decreases expression
ISO
EXP
Deferoxamine results in increased expression of CDKN1A mRNA; Deferoxamine results in increased expression of CDKN1A protein
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA]
Deferoxamine results in decreased expression of CDKN1A protein
CTD PMID:10397746 PMID:10559391 PMID:11468187 PMID:12807743 PMID:16227210 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1B mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA] CTD PMID:33962019 PMID:35690295 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Ckb creatine kinase B multiple interactions EXP [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein] CTD PMID:19688255 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] CTD PMID:11306436 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions ISO Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] CTD PMID:18515279 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cp ceruloplasmin multiple interactions ISO Deferoxamine inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl] CTD PMID:22824865 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity EXP Deferoxamine results in increased activity of CREB1 protein CTD PMID:10559391 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crp C-reactive protein multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein] CTD PMID:30431687 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] CTD PMID:20801209 PMID:21703343 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Oxygen deficiency co-treated with Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] affects the localization of CTNNB1 protein; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of CTNNB1 protein] CTD PMID:20338187 PMID:34648812 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsk cathepsin K multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA] CTD PMID:31238089 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP Deferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL2] CTD PMID:21605006 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Deferoxamine co-treated with Benzene] results in increased expression of CYBB protein; Deferoxamine inhibits the reaction [Benzene results in increased expression of CYBB mRNA] CTD PMID:35661779 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
ISO [Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA]
Deferoxamine results in increased expression of CYCS mRNA
CTD PMID:33962019 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]
Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]
CTD PMID:10799651 PMID:10823667 PMID:20801209 PMID:21703343 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression ISO Deferoxamine results in decreased expression of CYP3A4 mRNA; Deferoxamine results in decreased expression of CYP3A4 protein CTD PMID:19695866 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein] CTD PMID:23764342 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Des desmin multiple interactions
increases expression
ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]
Deferoxamine results in increased expression of DES mRNA
CTD PMID:30551460 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
multiple interactions
ISO Deferoxamine results in increased expression of DIABLO mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA]
CTD PMID:33962019 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Deferoxamine results in decreased expression of DICER1 mRNA; Deferoxamine results in decreased expression of DICER1 protein CTD PMID:25351418 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity EXP Deferoxamine results in increased activity of DIO2 protein CTD PMID:17615150 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]
[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA]
CTD PMID:26318285 PMID:33962019 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression
decreases expression
ISO Deferoxamine results in increased expression of DNMT1 mRNA
Deferoxamine results in decreased expression of DNMT1 mRNA
CTD PMID:23483119 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO Deferoxamine results in decreased expression of DNMT3A mRNA
Deferoxamine results in increased expression of DNMT3A mRNA
CTD PMID:23483119 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
increases expression
ISO Deferoxamine results in decreased expression of DNMT3B mRNA
Deferoxamine results in increased expression of DNMT3B mRNA
CTD PMID:23483119 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX1 mRNA] CTD PMID:21703343 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX2 mRNA] CTD PMID:21703343 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Deferoxamine results in increased expression of DUSP1 mRNA CTD PMID:11577072 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Edn1 endothelin 1 increases expression EXP Deferoxamine results in increased expression of EDN1 protein CTD PMID:9357851 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA] CTD PMID:15626777 PMID:35690295 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases expression ISO Deferoxamine results in decreased expression of EGLN1 protein CTD PMID:22245592 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO Deferoxamine results in decreased expression of EHMT2 mRNA CTD PMID:23483119 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] CTD PMID:11919081 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Eno1 enolase 1 increases expression ISO Deferoxamine results in increased expression of ENO1 mRNA CTD PMID:16227210 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
increases expression
increases stability
ISO
EXP
Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein]
Deferoxamine results in increased expression of EPAS1 protein
Deferoxamine results in increased stability of EPAS1 protein
CTD PMID:18353899 PMID:18515279 PMID:21558026 PMID:22447124 PMID:26735578 More... NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epo erythropoietin increases expression
increases stability
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of EPO mRNA
Deferoxamine deficiency results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO mRNA
Deferoxamine deficiency results in increased stability of EPO mRNA
Deferoxamine results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO protein
Deferoxamine inhibits the reaction [Reactive Oxygen Species results in decreased expression of EPO protein]
CTD PMID:9927288 PMID:10559391 PMID:10699462 PMID:10756076 PMID:21558026 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO
EXP
Deferoxamine results in increased expression of ERO1A mRNA CTD PMID:12752442 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ERP29 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein]
CTD PMID:19515424 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Exo1 exonuclease 1 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA] CTD PMID:35690295 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA] CTD PMID:25858758 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Deferoxamine results in decreased expression of FABP4 mRNA CTD PMID:12032628 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of FASN protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of FASN protein] CTD PMID:34648812 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fech ferrochelatase decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of FECH protein
ferric chloride inhibits the reaction [Deferoxamine results in decreased expression of FECH protein]
CTD PMID:30517741 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA] CTD PMID:33962019 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA] CTD PMID:30551460 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression
multiple interactions
ISO
EXP
Deferoxamine results in decreased expression of FTH1 protein
Deferoxamine inhibits the reaction [Benzene results in increased expression of FTH1 mRNA]; Deferoxamine inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein]
Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein]
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTH1 mRNA
CTD PMID:15893546 PMID:16568477 PMID:16777245 PMID:17469137 PMID:32687844 More... NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
decreases expression
ISO
EXP
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTL mRNA; Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]
Deferoxamine inhibits the reaction [Benzene results in increased expression of FTL1 protein]
Deferoxamine results in decreased expression of FTL1 protein
CTD PMID:12393473 PMID:12644586 PMID:15893546 PMID:16568477 PMID:35661779 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions ISO Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]] CTD PMID:12644586 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Deferoxamine results in increased expression of GADD45A mRNA CTD PMID:10397746 PMID:11468187 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of GAPDH protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein]
CTD PMID:19515424 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of GAS1 mRNA CTD PMID:12393473 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases expression ISO Deferoxamine results in increased expression of GBE1 mRNA CTD PMID:15094311 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gck glucokinase affects expression EXP Deferoxamine affects the expression of GCK mRNA CTD PMID:9761743 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO Deferoxamine inhibits the reaction [Benzene results in decreased expression of GCLC mRNA] CTD PMID:35661779 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Glo1 glyoxalase 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of GLO1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein]
CTD PMID:19515424 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 multiple interactions ISO GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]] CTD PMID:31066958 NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177
Ensembl chr10:61,450,494...61,607,177
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Deferoxamine inhibits the reaction [Benzene results in decreased expression of GPX4 mRNA]; Deferoxamine inhibits the reaction [Benzene results in decreased expression of GPX4 protein]; Deferoxamine inhibits the reaction [Busulfan results in decreased expression of GPX4 protein]
Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]
CTD PMID:32416107 PMID:35661779 PMID:36843388 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
ISO
EXP
Deferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein]
Deferoxamine results in decreased phosphorylation of GSK3B protein
CTD PMID:25246272 PMID:34577062 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein] CTD PMID:22115772 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
affects expression
ISO
EXP
Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]
Deferoxamine results in decreased expression of HAMP protein
Deferoxamine affects the expression of HAMP mRNA
CTD PMID:21558026 PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein] CTD PMID:30431687 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
increases stability
increases activity
decreases degradation
affects localization
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HIF1A mRNA; [Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA; [Doxorubicin co-treated with Deferoxamine] results in increased expression of HIF1A protein; [Glucose co-treated with Deferoxamine] results in increased expression of HIF1A mRNA; [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; Cadmium inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]]; Deferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Deferoxamine results in increased expression of and results in increased stability of HIF1A protein; Deferoxamine results in increased stability of and results in increased expression of HIF1A protein; dihydrotanshinone I inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of HIF1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HIF1A mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]
Deferoxamine results in increased expression of HIF1A mRNA; Deferoxamine results in increased expression of HIF1A protein
Deferoxamine results in increased stability of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]
Deferoxamine results in increased activity of HIF1A protein
[Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine
Deferoxamine results in decreased degradation of HIF1A protein
Deferoxamine affects the localization of HIF1A protein
CTD PMID:10559391 PMID:10866824 PMID:11286986 PMID:12393473 PMID:14604972 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO Deferoxamine results in increased expression of HIF3A protein CTD PMID:16775626 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Hk2 hexokinase 2 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of HK2 protein
Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein]]; Doxorubicin inhibits the reaction [Deferoxamine results in increased expression of HK2 protein]
CTD PMID:34126102 PMID:36116563 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases degradation
decreases expression
ISO
EXP
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]
Deferoxamine results in decreased degradation of HMOX1 protein
Deferoxamine results in decreased expression of HMOX1 mRNA
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HMOX1 mRNA; Deferoxamine affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]; Deferoxamine inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]
CTD PMID:9747510 PMID:10814519 PMID:12393473 PMID:16439612 PMID:18073186 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein]
Deferoxamine results in decreased expression of HSPA1A protein
CTD PMID:19515424 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA] CTD PMID:35690295 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
decreases expression
ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPD1 mRNA; ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPD1 mRNA]
Deferoxamine results in decreased expression of HSPD1 protein
CTD PMID:19515424 PMID:24170104 PMID:35690295 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPH1 mRNA CTD PMID:12393473 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12633744 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein] CTD PMID:30431687 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:21703343 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ferric chloride inhibits the reaction [Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]
Deferoxamine results in increased expression of IL1B mRNA
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Deferoxamine results in decreased expression of IL1B mRNA
CTD PMID:9851740 PMID:18403674 PMID:20801209 PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 multiple interactions EXP Deferoxamine inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA] CTD PMID:11222498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
Deferoxamine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]; Deferoxamine inhibits the reaction [Coal Ash results in increased expression of IL6 protein]
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of IL6 protein]; Deferoxamine inhibits the reaction [Asbestos, Amphibole results in increased expression of IL6 mRNA]
CTD PMID:9344885 PMID:22168577 PMID:24296301 PMID:34577062 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 increases secretion EXP Deferoxamine results in increased secretion of INS1 protein CTD PMID:30382123 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression
increases activity
multiple interactions
EXP
ISO
Deferoxamine results in increased expression of IREB2 protein
Deferoxamine results in increased activity of IREB2 protein
Deferoxamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein]; Deferoxamine results in increased expression of and results in increased activity of IREB2 protein
CTD PMID:10397746 PMID:11054110 PMID:16135072 PMID:16568477 PMID:17469137 More... NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ITGB3 mRNA
Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA]
CTD PMID:31238089 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of JUN mRNA CTD PMID:12393473 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO Deferoxamine results in decreased expression of and results in decreased activity of KDM1A protein CTD PMID:23483119 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO Deferoxamine results in increased expression of KDM3A protein CTD PMID:23546878 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kdm4a lysine demethylase 4A multiple interactions ISO Deferoxamine results in decreased expression of and results in decreased activity of KDM4A protein CTD PMID:23483119 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of KDR mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of KDR mRNA] CTD PMID:33962019 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Deferoxamine affects the reaction [Magnetite Nanoparticles results in increased expression of LCN2 mRNA]; Deferoxamine inhibits the reaction [LCN2 protein results in decreased secretion of VEGFA protein]
Deferoxamine results in increased expression of LCN2 mRNA
CTD PMID:17114340 PMID:23086747 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldha lactate dehydrogenase A increases expression
multiple interactions
ISO Deferoxamine results in increased expression of LDHA mRNA
Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein]]
CTD PMID:34998824 PMID:36116563 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lep leptin increases expression
increases secretion
ISO
EXP
Deferoxamine results in increased expression of LEP mRNA
Deferoxamine results in increased secretion of LEP protein
CTD PMID:12032628 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression ISO Deferoxamine results in decreased expression of LIPE mRNA CTD PMID:12032628 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lox lysyl oxidase multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of MAP1LC3A protein] CTD PMID:21742779 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO Deferoxamine results in increased expression of MAP1LC3B protein
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Iron affects the reaction [Deferoxamine results in increased expression of MAP1LC3B protein]
CTD PMID:25301941 PMID:32687844 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAP3K5 protein] CTD PMID:20206247 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK1 protein]
Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]
[Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]
Deferoxamine results in increased phosphorylation of MAPK1 protein
CTD PMID:11933051 PMID:16527254 PMID:18032466 PMID:20368581 PMID:31066958 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK3 protein]
Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]]
[Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]
Deferoxamine results in increased phosphorylation of MAPK3 protein
CTD PMID:11933051 PMID:16527254 PMID:18032466 PMID:20368581 PMID:31066958 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Deferoxamine results in increased phosphorylation of MAPK8 protein
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]
CTD PMID:20206247 PMID:20368581 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Deferoxamine results in increased phosphorylation of MAPK9 protein
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK9 protein]
CTD PMID:20206247 PMID:20368581 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
increases cleavage
ISO Nitroprusside inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein] CTD PMID:16374551 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mff mitochondrial fission factor increases expression
multiple interactions
ISO Deferoxamine results in increased expression of MFF mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of MFF mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of MFF mRNA]
CTD PMID:33962019 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA; Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mief2 mitochondrial elongation factor 2 multiple interactions
increases expression
ISO [Glucose co-treated with Deferoxamine] results in increased expression of MIEF2 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of MIEF2 mRNA]
Deferoxamine results in increased expression of MIEF2 mRNA
CTD PMID:33962019 NCBI chr10:45,408,055...45,414,144
Ensembl chr10:45,408,082...45,414,144
JBrowse link
G Mir155 microRNA 155 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR155 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR155 mRNA] CTD PMID:35690295 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir184 microRNA 184 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR184 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in decreased expression of BCL2 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of AKT1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of ARNT mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HIF1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPD1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR155 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP3 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MTOR mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of PIK3R1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of SOD1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TNFSF10 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of VEGFA mRNA] CTD PMID:35690295 NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210
JBrowse link
G Mir210 microRNA 210 increases expression
increases expression
ISO Deferoxamine results in increased expression of MIR210 mRNA
desferrioxamine B increases expression of MIR210 miRNA in trophoblast cells
CTD
RGD
PMID:24577088 PMID:22840297 RGD:155631283 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mlh1 mutL homolog 1 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA] CTD PMID:35690295 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA] CTD PMID:10464329 PMID:19136476 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of MMP2 protein]; ferric chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein] CTD PMID:10086886 PMID:20338187 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP3 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP3 mRNA] CTD PMID:35690295 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA]
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA]
Deferoxamine results in decreased expression of MMP9 mRNA
CTD PMID:31238089 PMID:35690295 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions
increases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 9:45,113,554...45,172,375
Ensembl chr 9:45,113,554...45,172,375
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression ISO Deferoxamine results in decreased expression of ATP6 mRNA CTD PMID:31238089 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression ISO Deferoxamine results in decreased expression of ATP8 mRNA CTD PMID:31238089 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Deferoxamine results in decreased expression of COX1 mRNA CTD PMID:31238089 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Deferoxamine results in decreased expression of COX2 mRNA CTD PMID:31238089 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Deferoxamine results in decreased expression of COX3 mRNA CTD PMID:31238089 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO Deferoxamine results in decreased expression of CYTB mRNA CTD PMID:31238089 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 decreases expression ISO Deferoxamine results in decreased expression of ND1 mRNA CTD PMID:31238089 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression ISO Deferoxamine results in decreased expression of ND2 mRNA CTD PMID:31238089 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression ISO Deferoxamine results in decreased expression of ND3 mRNA CTD PMID:31238089 NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression ISO Deferoxamine results in decreased expression of ND4 mRNA CTD PMID:31238089 NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression ISO Deferoxamine results in decreased expression of ND4L mRNA CTD PMID:31238089 NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression ISO Deferoxamine results in decreased expression of ND5 mRNA CTD PMID:31238089 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression ISO Deferoxamine results in decreased expression of ND6 mRNA CTD PMID:31238089 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MTOR mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MTOR mRNA] CTD PMID:35690295 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] CTD PMID:11919081 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases degradation
decreases expression
multiple interactions
ISO Deferoxamine results in increased degradation of MYC protein
Deferoxamine results in decreased expression of MYC protein
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of MYC mRNA
CTD PMID:12393473 PMID:20046830 PMID:22245592 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of NCOA4 protein]; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 PMID:32687844 PMID:36843388 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
decreases response to substance
ISO Deferoxamine results in increased expression of NDRG1 mRNA; Deferoxamine results in increased expression of NDRG1 protein
NDRG1 protein results in decreased susceptibility to Deferoxamine
CTD PMID:11006124 PMID:24532803 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression ISO Deferoxamine results in decreased expression of NDUFB8 protein CTD PMID:31238089 NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817
JBrowse link
G Nes nestin decreases expression ISO Deferoxamine results in decreased expression of NES mRNA CTD PMID:16772336 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Deferoxamine inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NFE2L2 protein]; Deferoxamine inhibits the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of NFE2L2 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]]
Deferoxamine inhibits the reaction [Busulfan results in decreased expression of NFE2L2 protein]
CTD PMID:26945724 PMID:31066958 PMID:32416107 PMID:36450496 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:30431687 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP
ISO
Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine]
[Deferoxamine results in increased expression of NOS2 mRNA] which results in increased abundance of Nitric Oxide
CTD PMID:7532384 PMID:18073202 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of NQO1 mRNA
Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]
CTD PMID:14645679 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression ISO Deferoxamine results in decreased expression of OLR1 protein CTD PMID:24170104 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions
increases expression
ISO [Glucose co-treated with Deferoxamine] results in increased expression of OPA1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of OPA1 mRNA]
Deferoxamine results in increased expression of OPA1 mRNA
CTD PMID:33962019 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of P4HA1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein]
CTD PMID:19515424 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Deferoxamine results in increased cleavage of PARP1 protein
Indomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]; Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]
CTD PMID:21882223 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA] CTD PMID:11306436 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18032466 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression EXP Deferoxamine results in decreased expression of PDGFRB protein CTD PMID:18032466 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta increases expression
multiple interactions
ISO Deferoxamine results in increased expression of PDHB protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein]
CTD PMID:19515424 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Deferoxamine results in increased expression of PDK1 mRNA CTD PMID:21558026 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions
increases expression
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein]
Deferoxamine results in increased expression of PGK1 mRNA
Deferoxamine results in decreased expression of PGK1 protein
CTD PMID:19515424 PMID:22447124 PMID:34998824 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of PIK3R1 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of PIK3R1 mRNA] CTD PMID:35690295 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 multiple interactions ISO Deferoxamine results in increased expression of and affects the localization of PLAGL2 protein CTD PMID:11832486 NCBI chr 3:141,695,322...141,708,516
Ensembl chr 3:141,695,322...141,708,503
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased activity of PLAU mRNA]; Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased expression of PLAU mRNA] CTD PMID:17571974 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein] CTD PMID:34648812 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of PMAIP1 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of PMAIP1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PMAIP1 mRNA]
CTD PMID:33962019 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO Deferoxamine results in increased expression of POU5F1 mRNA CTD PMID:22447124 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein]
Deferoxamine results in decreased expression of PPIA protein
CTD PMID:19515424 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Prkcd protein kinase C, delta increases phosphorylation ISO Deferoxamine results in increased phosphorylation of PRKCD protein CTD PMID:17097691 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases stability
increases expression
multiple interactions
ISO Deferoxamine results in increased stability of PTGS2 protein
Deferoxamine results in increased expression of PTGS2 mRNA; Deferoxamine results in increased expression of PTGS2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; [Sulindac co-treated with Deferoxamine] results in increased expression of PTGS2 protein; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; Indomethacin promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; Deferoxamine inhibits the reaction [Benzene results in increased expression of PTGS2 mRNA]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]
CTD PMID:16527254 PMID:21882223 PMID:32816093 PMID:35661779 PMID:36843388 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of RACK1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein]
CTD PMID:19515424 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Ramp2 receptor activity modifying protein 2 decreases expression ISO Deferoxamine results in decreased expression of RAMP2 mRNA CTD PMID:11754965 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Deferoxamine results in decreased phosphorylation of RB1 protein CTD PMID:11468187 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of RELA protein] CTD PMID:34577062 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO Deferoxamine results in decreased expression of RUNX2 mRNA CTD PMID:16772336 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sag S-antigen visual arrestin multiple interactions EXP Deferoxamine inhibits the reaction [SAG results in increased abundance of Free Radicals] CTD PMID:8407215 NCBI chr 9:88,467,797...88,508,821
Ensembl chr 9:88,469,376...88,508,820
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression ISO Deferoxamine results in decreased expression of SDHB protein CTD PMID:31238089 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sele selectin E multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:12633744 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO Deferoxamine inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Setd1a SET domain containing 1A, histone lysine methyltransferase increases expression ISO Deferoxamine results in increased expression of SETD1A mRNA CTD PMID:23483119 NCBI chr 1:182,386,197...182,411,695
Ensembl chr 1:182,388,060...182,411,090
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase increases expression
affects expression
ISO Deferoxamine results in increased expression of SETD2 mRNA
Deferoxamine affects the expression of SETD2 mRNA
CTD PMID:23483119 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO Deferoxamine results in increased expression of SIRT1 protein CTD PMID:22245592 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions
decreases expression
increases expression
EXP
ISO
[Deferoxamine co-treated with Manganese] results in increased expression of SLC11A2; [Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]] which results in increased uptake of Copper; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 mRNA]; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]
Deferoxamine results in decreased expression of SLC11A2 mRNA
Deferoxamine results in increased expression of SLC11A2 protein
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of SLC11A2 mRNA; [Deferoxamine results in increased expression of SLC11A2 protein] which results in increased uptake of Manganese; Deferoxamine promotes the reaction [Deferoxamine results in increased expression of SLC11A2 protein]
CTD PMID:11933051 PMID:12393473 PMID:23764342 PMID:24089420 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression ISO Deferoxamine results in decreased expression of SLC19A2 mRNA CTD PMID:34998824 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
JBrowse link
G Slc19a3 solute carrier family 19 member 3 decreases expression ISO Deferoxamine results in decreased expression of SLC19A3 mRNA CTD PMID:34998824 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression
ISO [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of SLC2A1 protein; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]]
Deferoxamine results in increased expression of SLC2A1 mRNA
CTD PMID:12032628 PMID:17442736 PMID:21558026 PMID:36116563 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO Deferoxamine results in decreased expression of SLC2A4 mRNA CTD PMID:12032628 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of SLC40A1 protein
Deferoxamine inhibits the reaction [Busulfan results in decreased expression of SLC40A1 protein]
CTD PMID:31238089 PMID:32416107 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc44a4 solute carrier family 44, member 4 decreases expression ISO Deferoxamine results in decreased expression of SLC44A4 mRNA CTD PMID:34998824 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
G Slc6a2 solute carrier family 6 member 2 decreases expression EXP Deferoxamine results in decreased expression of SLC6A2 protein CTD PMID:16650837 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of SLC7A11 mRNA
Deferoxamine affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SLC7A11 protein]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]
Deferoxamine inhibits the reaction [Benzene results in decreased expression of SLC7A11 mRNA]; Deferoxamine promotes the reaction [Benzene results in decreased expression of SLC7A11 protein]
CTD PMID:32816093 PMID:35661779 PMID:36450496 PMID:36843388 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Deferoxamine results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of SOD1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of SOD1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of SOD1 mRNA] CTD PMID:35690295 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of SOD2 mRNA; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; TRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]
Deferoxamine inhibits the reaction [SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]]
CTD PMID:10464329 PMID:16927372 PMID:19063909 PMID:35690295 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein] CTD PMID:12633744 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Deferoxamine inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA] CTD PMID:21467157 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of SQSTM1 protein
[Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; [Iron co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]
CTD PMID:25301941 PMID:32283200 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] CTD PMID:34648812 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 multiple interactions ISO ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein] CTD PMID:29475939 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] CTD PMID:30431687 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase increases expression
decreases expression
ISO Deferoxamine results in increased expression of SUV39H1 mRNA
Deferoxamine results in decreased expression of SUV39H1 mRNA
CTD PMID:23483119 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 decreases expression
increases expression
ISO Deferoxamine results in decreased expression of SUV39H1 mRNA
Deferoxamine results in increased expression of SUV39H1 mRNA
CTD PMID:23483119 NCBI chr  X:141,792,589...141,795,257 JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 decreases expression ISO Deferoxamine results in decreased expression of TET2 protein CTD PMID:23483119 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
JBrowse link
G Tf transferrin multiple interactions ISO Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein] CTD PMID:31238089 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO Deferoxamine results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor increases expression
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of TFRC mRNA; Deferoxamine results in increased expression of TFRC protein
Deferoxamine inhibits the reaction [Doxorubicin results in decreased expression of TFRC mRNA]
[Deferoxamine co-treated with Benzene] results in increased expression of TFRC protein; Deferoxamine affects the reaction [Magnetite Nanoparticles results in decreased expression of TFRC mRNA]; Deferoxamine promotes the reaction [Busulfan results in decreased expression of TFRC protein]
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of TFRC mRNA; [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of TFRC protein
CTD PMID:11054110 PMID:12393473 PMID:12807743 PMID:15993339 PMID:16039939 More... NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA] CTD PMID:11306436 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase increases expression EXP Deferoxamine results in increased expression of TH mRNA CTD PMID:9458725 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Deferoxamine results in decreased expression of TLR4 protein CTD PMID:24170104 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases response to substance
decreases expression
decreases activity
ISO
EXP
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TNF mRNA; Deferoxamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine results in decreased activity of TNF protein]
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]
Deferoxamine results in increased susceptibility to TNF protein
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of TNF protein]; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine]
Deferoxamine results in decreased expression of TNF mRNA
CTD PMID:7532384 PMID:7539275 PMID:9851740 PMID:10486238 PMID:12633744 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Deferoxamine results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A decreases expression ISO Deferoxamine results in decreased expression of TNFRSF11A mRNA CTD PMID:31238089 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TNFSF10 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TNFSF10 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TNFSF10 mRNA] CTD PMID:35690295 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:31238089 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
decreases response to substance
ISO
EXP
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of TP53 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA]; Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]; Deferoxamine inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of TP53 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]; TP53 protein affects the reaction [Deferoxamine results in increased expression of BAX protein]
Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of TP53 mRNA]
Deferoxamine results in increased expression of TP53 protein
TP53 protein results in decreased susceptibility to Deferoxamine
CTD PMID:10942736 PMID:16357363 PMID:16527254 PMID:23483119 PMID:33962019 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpd52l1 TPD52 like 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of TPD52L1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein]
CTD PMID:19515424 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Deferoxamine results in increased expression of TPI1 mRNA CTD PMID:14762718 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Trap1 TNF receptor-associated protein 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of TRAP1 mRNA; Deferoxamine results in decreased expression of TRAP1 protein
TRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]
CTD PMID:16927372 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression ISO Deferoxamine results in increased expression of TUBB3 mRNA CTD PMID:16772336 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO Deferoxamine results in decreased expression of UCP2 mRNA CTD PMID:12032628 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO
EXP
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of VCAM1 protein]
CTD PMID:12633744 PMID:30431687 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein]
Deferoxamine results in decreased expression of VDAC2 protein
CTD PMID:19515424 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vdr vitamin D receptor increases expression ISO Deferoxamine results in increased expression of VDR mRNA CTD PMID:20368581 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
increases secretion
ISO
EXP
Deferoxamine inhibits the reaction [LCN2 protein results in decreased secretion of VEGFA protein]
Deferoxamine results in increased expression of VEGFA mRNA
Deferoxamine results in increased expression of VEGFA mRNA; Deferoxamine results in increased expression of VEGFA protein
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of VEGFA mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of VEGFA mRNA; Deferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]; Deferoxamine promotes the reaction [Potassium Dichromate results in increased expression of VEGFA protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of VEGFA mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of VEGFA mRNA]
Deferoxamine results in increased secretion of VEGFA protein
CTD PMID:10613739 PMID:12213806 PMID:15075239 PMID:16227210 PMID:17114340 More... NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor multiple interactions ISO VHL protein mutant form affects the reaction [Deferoxamine results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:18515279 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
G Wt1 WT1 transcription factor multiple interactions ISO [cobaltous chloride co-treated with Deferoxamine] results in increased expression of WT1 mRNA CTD PMID:12738801 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
dinophysistoxin 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO dinophysistoxin 1 results in increased expression of ABTB2 mRNA CTD PMID:28939011 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO dinophysistoxin 1 results in increased expression of ALDOC mRNA CTD PMID:28939011 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO dinophysistoxin 1 results in increased expression of ATF3 mRNA CTD PMID:28939011 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atxn3 ataxin 3 increases expression ISO dinophysistoxin 1 results in increased expression of ATXN3 mRNA CTD PMID:28939011 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Bace1 beta-secretase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of BACE1 mRNA CTD PMID:28939011 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO dinophysistoxin 1 results in increased expression of BCL2L11 mRNA CTD PMID:28939011 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bfsp1 beaded filament structural protein 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of BFSP1 mRNA CTD PMID:28939011 NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337
JBrowse link
G Bik BCL2-interacting killer increases expression ISO dinophysistoxin 1 results in increased expression of BIK mRNA CTD PMID:28939011 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO dinophysistoxin 1 results in increased expression of BPGM mRNA CTD PMID:28939011 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
JBrowse link
G C3h11orf96 similar to human chromosome 11 open reading frame 96 increases expression ISO dinophysistoxin 1 results in increased expression of C11ORF96 mRNA CTD PMID:28939011 NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
JBrowse link
G C9H2orf15 chromosome 9 C2orf15 homolog decreases expression ISO dinophysistoxin 1 results in decreased expression of C2ORF15 mRNA CTD PMID:28939011
G Calr calreticulin increases expression ISO dinophysistoxin 1 results in increased expression of CALR mRNA CTD PMID:28939011 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Canx calnexin increases expression ISO dinophysistoxin 1 results in increased expression of CANX mRNA CTD PMID:28939011 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Cck cholecystokinin increases expression ISO dinophysistoxin 1 results in increased expression of CCK mRNA CTD PMID:28939011 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression ISO dinophysistoxin 1 results in increased expression of CCT4 mRNA CTD PMID:28939011 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression ISO dinophysistoxin 1 results in increased expression of CCT7 mRNA CTD PMID:28939011 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cd44 CD44 molecule increases expression ISO dinophysistoxin 1 results in increased expression of CD44 mRNA CTD PMID:28939011 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO dinophysistoxin 1 results in increased expression of CDKN1C mRNA CTD PMID:21853993 PMID:28939011 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO dinophysistoxin 1 results in increased expression of CEACAM1 mRNA CTD PMID:21853993 PMID:28939011 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO dinophysistoxin 1 results in increased expression of CEBPB mRNA CTD PMID:28939011 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression ISO dinophysistoxin 1 results in increased expression of CHRNA7 mRNA CTD PMID:28939011 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chst9 carbohydrate sulfotransferase 9 decreases expression ISO dinophysistoxin 1 results in decreased expression of CHST9 mRNA CTD PMID:28939011 NCBI chr18:6,576,391...6,851,078
Ensembl chr18:6,577,348...6,850,868
JBrowse link
G Crebbp CREB binding protein increases expression ISO dinophysistoxin 1 results in increased expression of CREBBP mRNA CTD PMID:28939011 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of CREG2 mRNA CTD PMID:28939011 NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095
JBrowse link
G Cryl1 crystallin, lambda 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of CRYL1 mRNA CTD PMID:28939011 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Cul2 cullin 2 increases expression ISO dinophysistoxin 1 results in increased expression of CUL2 mRNA CTD PMID:28939011 NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO dinophysistoxin 1 results in increased expression of CXCR4 mRNA CTD PMID:28939011 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO dinophysistoxin 1 results in increased expression of DDIT3 mRNA CTD PMID:28939011 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO dinophysistoxin 1 results in increased expression of DDIT4 mRNA CTD PMID:21853993 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO dinophysistoxin 1 results in increased expression of DEPP1 mRNA CTD PMID:28939011 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO dinophysistoxin 1 results in decreased expression of DHCR24 mRNA CTD PMID:28939011 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of DHTKD1 mRNA CTD PMID:28939011 NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression ISO dinophysistoxin 1 results in increased expression of DLAT mRNA CTD PMID:28939011 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dmd dystrophin decreases expression ISO dinophysistoxin 1 results in decreased expression of DMD mRNA CTD PMID:28939011 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 increases expression ISO dinophysistoxin 1 results in increased expression of DNAJB2 mRNA CTD PMID:28939011 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO dinophysistoxin 1 results in increased expression of DNAJB9 mRNA CTD PMID:28939011 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression ISO dinophysistoxin 1 results in increased expression of DNAJC10 mRNA CTD PMID:28939011 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 decreases expression ISO dinophysistoxin 1 results in decreased expression of DNAJC4 mRNA CTD PMID:28939011 NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO dinophysistoxin 1 results in increased expression of DUSP4 mRNA CTD PMID:28939011 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO dinophysistoxin 1 results in increased expression of DUSP5 mRNA CTD PMID:28939011 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression ISO dinophysistoxin 1 results in increased expression of EGLN1 mRNA CTD PMID:28939011 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 increases expression ISO dinophysistoxin 1 results in increased expression of EGLN2 mRNA CTD PMID:28939011 NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO dinophysistoxin 1 results in increased expression of EGLN3 mRNA CTD PMID:28939011 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression ISO dinophysistoxin 1 results in increased expression of EGR1 mRNA CTD PMID:28939011 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elob elongin B increases expression ISO dinophysistoxin 1 results in increased expression of ELOB mRNA CTD PMID:28939011 NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
JBrowse link
G Eloc elongin C increases expression ISO dinophysistoxin 1 results in increased expression of ELOC mRNA CTD PMID:28939011 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO dinophysistoxin 1 results in increased expression of EMP1 mRNA CTD PMID:28939011 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
JBrowse link
G Eno2 enolase 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of ENO2 mRNA CTD PMID:28939011 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Eno3 enolase 3 increases expression ISO dinophysistoxin 1 results in increased expression of ENO3 mRNA CTD PMID:28939011 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Ep300 E1A binding protein p300 affects expression ISO dinophysistoxin 1 affects the expression of EP300 mRNA CTD PMID:28939011 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO dinophysistoxin 1 results in increased expression of EPAS1 mRNA CTD PMID:28939011 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of EPHX2 mRNA CTD PMID:28939011 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Epsti1 epithelial stromal interaction 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of EPSTI1 mRNA CTD PMID:28939011 NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO dinophysistoxin 1 results in increased expression of ERN1 mRNA CTD PMID:28939011 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta increases expression ISO dinophysistoxin 1 results in increased expression of ERO1B mRNA CTD PMID:28939011 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO dinophysistoxin 1 results in increased expression of F2RL1 mRNA CTD PMID:28939011 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fam120c family with sequence similarity 120 member C decreases expression ISO dinophysistoxin 1 results in decreased expression of FAM120C mRNA CTD PMID:28939011 NCBI chr  X:20,324,046...20,477,831
Ensembl chr  X:20,323,381...20,477,275
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of FDFT1 mRNA CTD PMID:28939011 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO dinophysistoxin 1 results in decreased expression of FDPS mRNA CTD PMID:28939011 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO dinophysistoxin 1 results in increased expression of FOS mRNA CTD PMID:28939011 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gpc5 glypican 5 decreases expression ISO dinophysistoxin 1 results in decreased expression of GPC5 mRNA CTD PMID:28939011 NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282
JBrowse link
G Gpi glucose-6-phosphate isomerase affects expression ISO dinophysistoxin 1 affects the expression of GPI mRNA CTD PMID:28939011 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTA1 mRNA CTD PMID:28939011 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTA4 mRNA CTD PMID:28939011 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTK1 mRNA CTD PMID:28939011 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO dinophysistoxin 1 results in increased expression of GSTM1 mRNA CTD PMID:28939011 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO dinophysistoxin 1 results in increased expression of GSTM3 mRNA CTD PMID:28939011 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO dinophysistoxin 1 results in increased expression of GSTP1 mRNA CTD PMID:28939011 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTZ1 mRNA CTD PMID:28939011 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO dinophysistoxin 1 results in decreased expression of H1-4 mRNA CTD PMID:28939011 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G Hebp1 heme binding protein 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of HEBP1 mRNA CTD PMID:28939011 NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects expression ISO dinophysistoxin 1 affects the expression of HIF1A mRNA CTD PMID:28939011 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor increases expression ISO dinophysistoxin 1 results in increased expression of HIF1AN mRNA CTD PMID:28939011 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha affects expression ISO dinophysistoxin 1 affects the expression of HIF3A mRNA CTD PMID:28939011 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of H2AC6 mRNA CTD PMID:28939011 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hk1 hexokinase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of HK1 mRNA CTD PMID:28939011 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 increases expression ISO dinophysistoxin 1 results in increased expression of HK2 mRNA CTD PMID:28939011 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase decreases expression ISO dinophysistoxin 1 results in decreased expression of HMGCL mRNA CTD PMID:28939011 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO dinophysistoxin 1 results in decreased expression of HMGCR mRNA CTD PMID:28939011 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO dinophysistoxin 1 results in increased expression of HSPA2 mRNA CTD PMID:28939011 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO dinophysistoxin 1 results in increased expression of HTRA2 mRNA CTD PMID:28939011 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ier3 immediate early response 3 increases expression ISO dinophysistoxin 1 results in increased expression of IER3 mRNA CTD PMID:28939011 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Iqcd IQ motif containing D increases expression ISO dinophysistoxin 1 results in increased expression of IQCD mRNA CTD PMID:28939011 NCBI chr12:35,955,522...35,972,420 JBrowse link
G Irs2 insulin receptor substrate 2 increases expression ISO dinophysistoxin 1 results in increased expression of IRS2 mRNA CTD PMID:28939011 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO dinophysistoxin 1 results in increased expression of JUN mRNA CTD PMID:28939011 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 decreases expression ISO dinophysistoxin 1 results in decreased expression of KCNJ16 mRNA CTD PMID:28939011 NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO dinophysistoxin 1 results in increased expression of KLF4 mRNA CTD PMID:28939011 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Lama1 laminin subunit alpha 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of LAMA1 mRNA CTD PMID:28939011 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO dinophysistoxin 1 results in increased expression of LDLR mRNA CTD PMID:28939011 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase increases expression ISO dinophysistoxin 1 results in increased expression of LFNG mRNA CTD PMID:28939011 NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression ISO dinophysistoxin 1 results in decreased expression of LGSN mRNA CTD PMID:28939011 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
JBrowse link
G Lyrm9 LYR motif containing 9 decreases expression ISO dinophysistoxin 1 results in decreased expression of LYRM9 mRNA CTD PMID:28939011 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772
JBrowse link
G Mab21l4 mab-21 like 4 decreases expression ISO dinophysistoxin 1 results in decreased expression of MAB21L4 mRNA CTD PMID:28939011 NCBI chr 9:93,690,455...93,701,267
Ensembl chr 9:93,690,999...93,700,506
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO dinophysistoxin 1 results in increased expression of MAFB mRNA CTD PMID:21853993 PMID:28939011 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO dinophysistoxin 1 results in increased expression of MANF mRNA CTD PMID:28939011 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO dinophysistoxin 1 results in increased expression of MAP2K3 mRNA CTD PMID:28939011 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO dinophysistoxin 1 results in increased expression of MAPK8 mRNA CTD PMID:28939011 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of MDH1 mRNA CTD PMID:28939011 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of MDH2 mRNA CTD PMID:28939011 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO dinophysistoxin 1 results in increased expression of MGST1 mRNA CTD PMID:28939011 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO dinophysistoxin 1 results in increased expression of MGST3 mRNA CTD PMID:28939011 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO dinophysistoxin 1 results in increased expression of MMP1 mRNA CTD PMID:28939011 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO dinophysistoxin 1 results in decreased expression of MVD mRNA CTD PMID:28939011 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Myo5c myosin VC decreases expression ISO dinophysistoxin 1 results in decreased expression of MYO5C mRNA CTD PMID:28939011 NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B decreases expression ISO dinophysistoxin 1 results in decreased expression of NEURL1B mRNA CTD PMID:28939011 NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 decreases expression ISO dinophysistoxin 1 results in decreased expression of NMNAT3 mRNA CTD PMID:28939011 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645
JBrowse link
G Nppb natriuretic peptide B decreases expression ISO dinophysistoxin 1 results in decreased expression of NPPB mRNA CTD PMID:21853993 PMID:28939011 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of NR2F2 mRNA CTD PMID:28939011 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO dinophysistoxin 1 results in increased expression of NR4A1 mRNA CTD PMID:28939011 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrip3 nuclear receptor interacting protein 3 increases expression ISO dinophysistoxin 1 results in increased expression of NRIP3 mRNA CTD PMID:28939011 NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600
JBrowse link
G Ntn4 netrin 4 decreases expression ISO dinophysistoxin 1 results in decreased expression of NTN4 mRNA CTD PMID:28939011 NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
JBrowse link
G Ogdhl oxoglutarate dehydrogenase L decreases expression ISO dinophysistoxin 1 results in decreased expression of OGDHL mRNA CTD PMID:28939011 NCBI chr16:7,578,343...7,604,385
Ensembl chr16:7,578,367...7,604,386
JBrowse link
G Osr2 odd-skipped related transciption factor 2 increases expression ISO dinophysistoxin 1 results in increased expression of OSR2 mRNA CTD PMID:21853993 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224
JBrowse link
G Palm3 paralemmin 3 decreases expression ISO dinophysistoxin 1 results in decreased expression of PALM3 mRNA CTD PMID:28939011 NCBI chr19:24,121,984...24,126,079
Ensembl chr19:24,122,239...24,130,448
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like decreases expression ISO dinophysistoxin 1 results in decreased expression of PDGFRL mRNA CTD PMID:28939011 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 affects expression ISO dinophysistoxin 1 affects the expression of PDHA1 mRNA CTD PMID:28939011 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of PDZK1 mRNA CTD PMID:28939011 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
JBrowse link
G Pfdn2 prefoldin subunit 2 increases expression ISO dinophysistoxin 1 results in increased expression of PFDN2 mRNA CTD PMID:28939011 NCBI chr13:83,772,301...83,791,367
Ensembl chr13:83,753,877...83,790,504
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO dinophysistoxin 1 results in decreased expression of PFKM mRNA CTD PMID:28939011 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of PGM1 mRNA CTD PMID:28939011 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 increases expression ISO dinophysistoxin 1 results in increased expression of PHLDA2 mRNA CTD PMID:28939011 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836
JBrowse link
G Pigz phosphatidylinositol glycan anchor biosynthesis, class Z decreases expression ISO dinophysistoxin 1 results in decreased expression of PIGZ mRNA CTD PMID:28939011 NCBI chr11:68,831,847...68,851,798 JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO dinophysistoxin 1 results in increased expression of PLAU mRNA CTD PMID:28939011 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO dinophysistoxin 1 results in increased expression of PLAUR mRNA CTD PMID:28939011 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO dinophysistoxin 1 results in increased expression of PLK2 mRNA CTD PMID:28939011 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO dinophysistoxin 1 results in increased expression of PLK3 mRNA CTD PMID:28939011 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO dinophysistoxin 1 results in increased expression of PPP1R15A mRNA CTD PMID:28939011 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO dinophysistoxin 1 results in increased expression of RASD1 mRNA CTD PMID:28939011 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rbks ribokinase decreases expression ISO dinophysistoxin 1 results in decreased expression of RBKS mRNA CTD PMID:28939011 NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290
JBrowse link
G Rbx1 ring-box 1 increases expression ISO dinophysistoxin 1 results in increased expression of RBX1 mRNA CTD PMID:28939011 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Reep1 receptor accessory protein 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of REEP1 mRNA CTD PMID:28939011 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO dinophysistoxin 1 results in increased expression of RGS16 mRNA CTD PMID:21853993 PMID:28939011 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rhoc ras homolog family member C increases expression ISO dinophysistoxin 1 results in increased expression of RHOC mRNA CTD PMID:28939011 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Rnf128 ring finger protein 128 decreases expression ISO dinophysistoxin 1 results in decreased expression of RNF128 mRNA CTD PMID:28939011 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423
JBrowse link
G Rps27a ribosomal protein S27a increases expression ISO dinophysistoxin 1 results in increased expression of RPS27A mRNA CTD PMID:28939011 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011
JBrowse link
G Sc5d sterol-C5-desaturase decreases expression ISO dinophysistoxin 1 results in decreased expression of SC5D mRNA CTD PMID:28939011 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
G Serpinb8 serpin family B member 8 increases expression ISO dinophysistoxin 1 results in increased expression of SERPINB8 mRNA CTD PMID:28939011 NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO dinophysistoxin 1 results in increased expression of SERPINE2 mRNA CTD PMID:28939011 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sil1 SIL1 nucleotide exchange factor decreases expression ISO dinophysistoxin 1 results in decreased expression of SIL1 mRNA CTD PMID:28939011 NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332
JBrowse link
G Slc16a3 solute carrier family 16 member 3 increases expression ISO dinophysistoxin 1 results in increased expression of SLC16A3 mRNA CTD PMID:28939011 NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of SLC1A1 mRNA CTD PMID:28939011 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO dinophysistoxin 1 results in increased expression of SLC2A1 mRNA CTD PMID:28939011 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO dinophysistoxin 1 results in decreased expression of SMIM14 mRNA CTD PMID:28939011 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression ISO dinophysistoxin 1 results in increased expression of SNAI1 mRNA CTD PMID:28939011 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sox8 SRY-box transcription factor 8 increases expression ISO dinophysistoxin 1 results in increased expression of SOX8 mRNA CTD PMID:28939011 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of SREBF2 mRNA CTD PMID:28939011 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 decreases expression ISO dinophysistoxin 1 results in decreased expression of STARD4 mRNA CTD PMID:28939011 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Tbc1d8b TBC1 domain family member 8B decreases expression ISO dinophysistoxin 1 results in decreased expression of TBC1D8B mRNA CTD PMID:28939011 NCBI chr  X:103,319,181...103,407,137
Ensembl chr  X:103,319,340...103,407,133
JBrowse link
G Tcp1 t-complex 1 increases expression ISO dinophysistoxin 1 results in increased expression of TCP1 mRNA CTD PMID:28939011 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tmem54 transmembrane protein 54 decreases expression ISO dinophysistoxin 1 results in decreased expression of TMEM54 mRNA CTD PMID:28939011 NCBI chr 5:141,449,191...141,455,683
Ensembl chr 5:141,449,191...141,455,682
JBrowse link
G Tor1a torsin family 1, member A increases expression ISO dinophysistoxin 1 results in increased expression of TOR1A mRNA CTD PMID:28939011 NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO dinophysistoxin 1 results in increased expression of TPI1 mRNA CTD PMID:28939011 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression ISO dinophysistoxin 1 results in increased expression of TUBB3 mRNA CTD PMID:21853993 PMID:28939011 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression ISO dinophysistoxin 1 results in increased expression of UBA52 mRNA CTD PMID:28939011 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
JBrowse link
G Ubb ubiquitin B increases expression ISO dinophysistoxin 1 results in increased expression of UBB mRNA CTD PMID:28939011 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
G Ubc ubiquitin C increases expression ISO dinophysistoxin 1 results in increased expression of UBC mRNA CTD PMID:28939011 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 increases expression ISO dinophysistoxin 1 results in increased expression of UBE2D1 mRNA CTD PMID:28939011 NCBI chr20:17,309,315...17,343,770
Ensembl chr20:17,309,315...17,342,295
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 increases expression ISO dinophysistoxin 1 results in increased expression of UBE2D2 mRNA CTD PMID:28939011 NCBI chr18:27,364,325...27,406,322
Ensembl chr18:27,364,303...27,406,181
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression ISO dinophysistoxin 1 results in increased expression of UBE2D3 mRNA CTD PMID:28939011 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
JBrowse link
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 increases expression ISO dinophysistoxin 1 results in increased expression of UGGT1 mRNA CTD PMID:28939011 NCBI chr 9:38,355,229...38,468,473
Ensembl chr 9:38,359,089...38,468,467
JBrowse link
G Vasn vasorin increases expression ISO dinophysistoxin 1 results in increased expression of VASN mRNA CTD PMID:21853993 PMID:28939011 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO dinophysistoxin 1 results in increased expression of VEGFA mRNA CTD PMID:28939011 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wnt6 Wnt family member 6 decreases expression ISO dinophysistoxin 1 results in decreased expression of WNT6 mRNA CTD PMID:28939011 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523
JBrowse link
G Zc3h6 zinc finger CCCH type containing 6 decreases expression ISO dinophysistoxin 1 results in decreased expression of ZC3H6 mRNA CTD PMID:28939011 NCBI chr 3:116,203,466...116,254,186
Ensembl chr 3:116,204,197...116,253,282
JBrowse link
dinophysistoxin 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccna1 cyclin A1 affects expression ISO dinophysistoxin 2 affects the expression of CCNA1 mRNA CTD PMID:21512803 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnb2 cyclin B2 affects expression ISO dinophysistoxin 2 affects the expression of CCNB2 mRNA CTD PMID:21512803 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO dinophysistoxin 2 results in decreased expression of CDK2 mRNA CTD PMID:21512803 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Tp53 tumor protein p53 affects localization ISO dinophysistoxin 2 affects the localization of TP53 protein CTD PMID:21512803 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
enniatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA
enniatins results in decreased expression of ABCA1 mRNA
CTD PMID:31100301 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Adm2 adrenomedullin 2 increases expression ISO enniatins results in increased expression of ADM2 mRNA CTD PMID:36016515 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression EXP enniatins results in decreased expression of AIFM1 mRNA CTD PMID:27163883 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 8:103,205,520...103,213,936
Ensembl chr 8:103,205,520...103,213,936
JBrowse link
G Artn artemin increases expression ISO enniatins results in increased expression of ARTN mRNA CTD PMID:36016515 NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
JBrowse link
G Atg12 autophagy related 12 decreases expression EXP enniatins results in decreased expression of ATG12 mRNA CTD PMID:27163883 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg3 autophagy related 3 decreases expression EXP enniatins results in decreased expression of ATG3 mRNA CTD PMID:27163883 NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Bcl2l11 Bcl2-like 11 decreases expression EXP enniatins results in decreased expression of BCL2L11 mRNA CTD PMID:27163883 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression EXP enniatins results in decreased expression of BNIP3L mRNA CTD PMID:27163883 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Btf3l4 basic transcription factor 3-like 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 5:123,567,902...123,587,527
Ensembl chr 5:123,567,907...123,586,866
JBrowse link
G Casp3 caspase 3 decreases expression EXP enniatins results in decreased expression of CASP3 mRNA CTD PMID:27163883 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase increases expression ISO enniatins results in increased expression of CAT mRNA CTD PMID:30259633 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccdc180 coiled-coil domain containing 180 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP enniatins results in decreased expression of CCNB2 mRNA CTD PMID:27163883 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccng1 cyclin G1 decreases expression EXP enniatins results in decreased expression of CCNG1 mRNA CTD PMID:27163883 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccnl2 cyclin L2 increases expression EXP enniatins results in increased expression of CCNL2 mRNA CTD PMID:27163883 NCBI chr 5:166,416,940...166,428,997
Ensembl chr 5:166,417,508...166,436,882
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 decreases expression ISO enniatins results in decreased expression of CCR5 mRNA CTD PMID:36016515 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd69 Cd69 molecule decreases expression ISO enniatins results in decreased expression of CD69 mRNA CTD PMID:36016515 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cd81 Cd81 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO enniatins results in increased expression of CHAC1 mRNA CTD PMID:36016515 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 decreases expression EXP enniatins results in decreased expression of CISD2 mRNA CTD PMID:27163883 NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein decreases expression EXP enniatins results in decreased expression of CLN8 mRNA CTD PMID:27163883 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr19:54,395,746...54,398,348
Ensembl chr19:54,395,742...54,399,407
JBrowse link
G Col6a2 collagen type VI alpha 2 chain decreases expression ISO enniatins results in decreased expression of COL6A2 mRNA CTD PMID:36016515 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Coro1c coronin 1C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
JBrowse link
G Csdc2 cold shock domain containing C2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule decreases expression EXP enniatins results in decreased expression of CXADR mRNA CTD PMID:27163883 NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO enniatins results in decreased expression of CXCL1 mRNA CTD PMID:30259633 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO enniatins results in decreased expression of CYP11A mRNA CTD PMID:25625232 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases expression ISO enniatins results in increased expression of CYP11B1 mRNA CTD PMID:25625232 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression ISO enniatins results in increased expression of CYP11B2 mRNA CTD PMID:25625232 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO enniatins results in decreased expression of CYP17A1 mRNA CTD PMID:25625232 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO enniatins results in increased expression of CYP19A1 mRNA CTD PMID:25625232 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO enniatins results in increased expression of CYP1A1 mRNA CTD PMID:25625232 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
JBrowse link
G Dctn6 dynactin subunit 6 decreases expression EXP enniatins results in decreased expression of DCTN6 mRNA CTD PMID:27163883 NCBI chr16:58,077,595...58,096,604
Ensembl chr16:58,077,585...58,096,968
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddx47 DEAD-box helicase 47 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Dnm1 dynamin 1 decreases expression EXP enniatins results in decreased expression of DNM1 mRNA CTD PMID:27163883 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression
ISO enniatins results in increased expression of EGR1 mRNA
enniatins results in decreased expression of EGR1 mRNA
CTD PMID:30227181 PMID:36016515 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Exph5 exophilin 5 increases expression ISO enniatins results in increased expression of EXPH5 mRNA CTD PMID:36016515 NCBI chr 8:53,698,825...53,775,371
Ensembl chr 8:53,698,852...53,773,169
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Gaa alpha glucosidase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression EXP enniatins results in decreased expression of GABARAPL1 mRNA CTD PMID:27163883 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gna14 G protein subunit alpha 14 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Golga1 golgin A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 3:22,765,690...22,812,637
Ensembl chr 3:22,767,761...22,812,585
JBrowse link
G Golph3 golgi phosphoprotein 3 decreases expression EXP enniatins results in decreased expression of GOLPH3 mRNA CTD PMID:27163883 NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr17 G protein-coupled receptor 17 increases expression ISO enniatins results in increased expression of GPR17 mRNA CTD PMID:36016515 NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
JBrowse link
G Gpr18 G protein-coupled receptor 18 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO enniatins results in increased expression of GPX1 mRNA CTD PMID:30259633 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 2:183,780,583...183,783,030 JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO enniatins results in decreased expression of HMGCR mRNA CTD PMID:25625232 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression
multiple interactions
ISO enniatins results in increased expression of HMGCS1 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA
CTD PMID:31100301 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression ISO enniatins results in decreased expression of HSD3B2 mRNA CTD PMID:25625232 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Igsf9 immunoglobulin superfamily, member 9 increases expression ISO enniatins results in increased expression of IGSF9 mRNA CTD PMID:36016515 NCBI chr13:84,948,643...84,965,616
Ensembl chr13:84,948,619...84,965,607
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO enniatins results in decreased expression of IL1B mRNA CTD PMID:30259633 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Immt inner membrane mitochondrial protein multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Jph3 junctophilin 3 increases expression ISO enniatins results in increased expression of JPH3 mRNA CTD PMID:36016515 NCBI chr19:49,793,967...49,855,338
Ensembl chr19:49,793,092...49,855,338
JBrowse link
G Klf12 KLF transcription factor 12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt16 keratin 16 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt27 keratin 27 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr10:84,298,684...84,303,967
Ensembl chr10:84,298,508...84,303,967
JBrowse link
G Krt5 keratin 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Krt76 keratin 76 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 decreases expression EXP enniatins results in decreased expression of MALSU1 mRNA CTD PMID:27163883 NCBI chr 4:78,051,090...78,059,913
Ensembl chr 4:78,051,059...78,059,905
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression EXP enniatins results in decreased expression of MAP3K1 mRNA CTD PMID:27163883 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Matn4 matrilin 4 increases expression ISO enniatins results in increased expression of MATN4 mRNA CTD PMID:36016515 NCBI chr 3:153,120,605...153,135,628
Ensembl chr 3:153,120,632...153,135,865
JBrowse link
G Mc2r melanocortin 2 receptor increases expression ISO enniatins results in increased expression of MC2R mRNA CTD PMID:25625232 NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488
JBrowse link
G Med6 mediator complex subunit 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr 6:101,270,410...101,283,929
Ensembl chr 6:101,270,410...101,283,876
JBrowse link
G Mef2a myocyte enhancer factor 2a decreases expression EXP enniatins results in decreased expression of MEF2A mRNA CTD PMID:27163883 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mief1 mitochondrial elongation factor 1 decreases expression EXP enniatins results in decreased expression of MIEF1 mRNA CTD PMID:27163883 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220
JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like decreases expression EXP enniatins results in decreased expression of MPV17L mRNA CTD PMID:27163883 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA; [Plant Extracts co-treated with enniatins] results in decreased expression of MRPL12 mRNA CTD PMID:31100301 PMID:31904472 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression
multiple interactions
ISO enniatins results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA
CTD PMID:30227181 PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression
multiple interactions
ISO enniatins results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA; [beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with enniatins] results in decreased expression of ATP8 mRNA
CTD PMID:30227181 PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX1 mRNA; [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with enniatins] results in decreased expression of COX1 mRNA
enniatins results in decreased expression of COX1 mRNA
CTD PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO enniatins results in decreased expression of COX2 mRNA CTD PMID:36016515 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression
multiple interactions
ISO enniatins results in decreased expression of COX3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA
CTD PMID:31100301 PMID:34015425 PMID:36016515 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO enniatins results in decreased expression of CYTB mRNA CTD PMID:30227181 PMID:36016515 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 decreases expression ISO enniatins results in decreased expression of ND1 mRNA CTD PMID:30227181 PMID:36016515 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression
multiple interactions
ISO enniatins results in decreased expression of ND2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA
CTD PMID:30227181 PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression
increases expression
multiple interactions
ISO enniatins results in decreased expression of ND3 mRNA
enniatins results in increased expression of ND3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with enniatins] results in increased expression of ND3 mRNA
CTD PMID:30227181 PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression
multiple interactions
ISO enniatins results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with enniatins] results in increased expression of ND4 mRNA
CTD PMID:30227181 PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression
multiple interactions
ISO enniatins results in decreased expression of ND4L mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND4L mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4L mRNA
CTD PMID:30227181 PMID:34015425 PMID:36016515 NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression
multiple interactions
ISO enniatins results in decreased expression of ND5 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND5 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND5 mRNA
CTD PMID:30227181 PMID:31100301 PMID:31904472 PMID:34015425 PMID:36016515 NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression
multiple interactions
ISO enniatins results in decreased expression of ND6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND6 mRNA
CTD PMID:30227181 PMID:34015425 PMID:36016515 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mterf4 mitochondrial transcription termination factor 4 decreases expression EXP enniatins results in decreased expression of MTERF4 mRNA CTD PMID:27163883 NCBI chr 9:93,834,162...93,838,838
Ensembl chr 9:93,834,144...93,838,864
JBrowse link
G Mtrf1l mitochondrial translation release factor 1 like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr 1:42,208,553...42,221,020
Ensembl chr 1:42,210,583...42,220,836
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr 1:151,300,446...151,412,086
Ensembl chr 1:151,300,467...151,413,521
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression EXP enniatins results in decreased expression of NDUFS4 mRNA CTD PMID:27163883 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO enniatins results in increased expression of NIBAN1 mRNA CTD PMID:36016515 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 increases expression ISO enniatins results in increased expression of NR0B1 mRNA CTD PMID:25625232 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nrf1 nuclear respiratory factor 1 decreases expression EXP enniatins results in decreased expression of NRF1 mRNA CTD PMID:27163883 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression
multiple interactions
ISO enniatins results in increased expression of OSGIN1 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of OSGIN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA
CTD PMID:31100301 PMID:34015425 PMID:36016515 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
JBrowse link
G Pam16 presequence translocase associated motor 16 decreases expression EXP enniatins results in decreased expression of PAM16 mRNA CTD PMID:27163883 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649
JBrowse link
G Parvg parvin, gamma multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr 7:115,456,183...115,475,707
Ensembl chr 7:115,456,209...115,475,104
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO enniatins results in increased expression of PCK2 mRNA CTD PMID:36016515 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pfn1 profilin 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PFN1 protein CTD PMID:32407736 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466
JBrowse link
G Pls3 plastin 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP enniatins results in decreased expression of PPP2CB mRNA CTD PMID:27163883 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psme4 proteasome activator subunit 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression ISO enniatins results in decreased expression of PTGDS mRNA CTD PMID:30227181 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO enniatins results in decreased expression of PTGS1 mRNA CTD PMID:30227181 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO enniatins results in decreased expression of PTGS2 mRNA CTD PMID:30227181 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rp2 RP2 activator of ARL3 GTPase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:1,872,582...1,916,704
Ensembl chr  X:1,873,306...1,916,688
JBrowse link
G Rpl37a ribosomal protein L37A multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rpl5 ribosomal protein L5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases expression EXP enniatins results in decreased expression of RRM2B mRNA CTD PMID:27163883 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Scml2 Scm polycomb group protein like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:33,523,179...33,677,672
Ensembl chr  X:33,524,530...33,652,742
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
JBrowse link
G Sdr42e2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr 1:175,361,630...175,382,769
Ensembl chr 1:175,362,150...175,382,050
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 decreases expression EXP enniatins results in decreased expression of SH3GLB1 mRNA CTD PMID:27163883 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc22a20 solute carrier family 22 member 20 increases expression ISO enniatins results in increased expression of SLC22A20P mRNA CTD PMID:36016515 NCBI chr 1:203,257,374...203,273,854
Ensembl chr 1:203,257,374...203,273,822
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression ISO enniatins results in increased expression of SLC6A9 mRNA CTD PMID:36016515 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO enniatins results in increased expression of SLC7A11 mRNA CTD PMID:30227181 PMID:31100301 PMID:36016515 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slit2 slit guidance ligand 2 decreases expression ISO enniatins results in decreased expression of SLIT2 mRNA CTD PMID:36016515 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO enniatins results in increased expression of SOD1 mRNA CTD PMID:30259633 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO enniatins results in increased expression of SOD2 mRNA CTD PMID:30259633 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spns3 sphingolipid transporter 3 increases expression ISO enniatins results in increased expression of SPNS3 mRNA CTD PMID:36016515 NCBI chr10:57,114,247...57,169,056
Ensembl chr10:57,114,266...57,168,951
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA CTD PMID:31100301 PMID:34015425 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Sspo SCO-spondin decreases expression ISO enniatins results in decreased expression of SSPO mRNA CTD PMID:36016515 NCBI chr 4:77,394,915...77,450,526
Ensembl chr 4:77,397,059...77,450,412
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO enniatins results in decreased expression of STAR mRNA CTD PMID:25625232 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO enniatins results in increased expression of STC2 mRNA CTD PMID:30227181 PMID:36016515 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Tbc1d2b TBC1 domain family, member 2B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr 8:90,746,220...90,814,867
Ensembl chr 8:90,746,233...90,814,832
JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
JBrowse link
G Tcp11l1 t-complex 11 like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr 3:91,047,006...91,092,687
Ensembl chr 3:90,998,270...91,092,006
JBrowse link
G Tcp11l2 t-complex 11 like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095
JBrowse link
G Tfb2m transcription factor B2, mitochondrial decreases expression EXP enniatins results in decreased expression of TFB2M mRNA CTD PMID:27163883 NCBI chr13:91,278,889...91,296,709
Ensembl chr13:91,278,898...91,296,657
JBrowse link
G Thyn1 thymocyte nuclear protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr 8:25,406,563...25,415,445
Ensembl chr 8:25,406,500...25,415,445
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 decreases expression EXP enniatins results in decreased expression of TIMM21 mRNA CTD PMID:27163883 NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
JBrowse link
G Timm8b translocase of inner mitochondrial membrane 8 homolog B decreases expression EXP enniatins results in decreased expression of TIMM8B mRNA CTD PMID:27163883 NCBI chr 8:50,954,350...50,955,730
Ensembl chr 8:50,954,342...50,955,729
JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr 6:89,610,094...89,622,924
Ensembl chr 6:89,610,094...89,622,924
JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tmem11 transmembrane protein 11 decreases expression EXP enniatins results in decreased expression of TMEM11 mRNA CTD PMID:27163883 NCBI chr10:45,542,753...45,557,570
Ensembl chr10:45,542,755...45,557,570
JBrowse link
G Tmem263 transmembrane protein 263 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr 7:18,610,151...18,628,311
Ensembl chr 7:18,610,149...18,628,534
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression EXP enniatins results in decreased expression of TNFSF10 mRNA CTD PMID:27163883 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 decreases expression EXP enniatins results in decreased expression of TOMM5 mRNA CTD PMID:27163883 NCBI chr 5:59,362,360...59,365,191
Ensembl chr 5:59,362,240...59,365,269
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit decreases expression EXP enniatins results in decreased expression of TRMT10C mRNA CTD PMID:27163883 NCBI chr11:44,584,388...44,589,466
Ensembl chr11:44,584,113...44,589,568
JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Tubb4a tubulin, beta 4A class IVa multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression
multiple interactions
EXP
ISO
enniatins results in decreased expression of TUBB5 mRNA
[beauvericin co-treated with enniatins] results in increased expression of TUBB protein
CTD PMID:27163883 PMID:32407736 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
ISO enniatins results in increased expression of TXNIP mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with enniatins] results in increased expression of TXNIP mRNA
CTD PMID:31100301 PMID:31904472 PMID:34015425 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO enniatins results in increased expression of UCP1 mRNA CTD PMID:30227181 PMID:36016515 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of UCP2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of UCP2 mRNA CTD PMID:31100301 PMID:34015425 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Vgll3 vestigial-like family member 3 increases expression ISO enniatins results in increased expression of VGLL3 mRNA CTD PMID:36016515 NCBI chr11:3,642,993...3,692,590
Ensembl chr11:3,643,069...3,689,140
JBrowse link
G Vpreb1a V-set pre-B cell surrogate light chain 1A increases expression ISO enniatins results in increased expression of VPREB1 mRNA CTD PMID:31100301 NCBI chr11:84,126,969...84,127,846
Ensembl chr11:84,126,969...84,127,846
JBrowse link
G Ykt6 YKT6 v-SNARE homolog multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma decreases expression EXP enniatins results in decreased expression of YWHAG mRNA CTD PMID:27163883 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
ionomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan multiple interactions ISO Ionomycin affects the reaction [CALR protein affects the expression of ACAN mRNA] CTD PMID:32220932 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Actb actin, beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA CTD PMID:15477007 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actn1 actinin, alpha 1 multiple interactions EXP Ionomycin promotes the reaction [CAMK2A protein binds to ACTN1 protein] CTD PMID:19217379 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Adm adrenomedullin decreases expression
multiple interactions
EXP
ISO
Ionomycin results in decreased expression of ADM mRNA
Ionomycin results in decreased expression of ADM mRNA; Ionomycin results in decreased expression of ADM protein
[Ionomycin co-treated with Lipopolysaccharides] results in decreased expression of ADM protein
CTD PMID:11470465 PMID:20682585 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of AHR mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and affects the localization of AHR protein CTD PMID:9415701 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; [Ionomycin co-treated with EGF protein] results in increased phosphorylation of AKT1 protein; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:22317921 PMID:28634229 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] CTD PMID:15477007 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA
Ionomycin results in increased expression of ATF4 protein
CTD PMID:15477007 PMID:32578922 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Thapsigargin co-treated with Ionomycin] promotes the reaction [STIM1 protein binds to ATP2A3 protein] CTD PMID:18439569 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Bach2 BTB domain and CNC homolog 2 increases expression ISO Ionomycin results in increased expression of BACH2 mRNA CTD PMID:24247028 NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877
JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA] CTD PMID:15477007 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Ionomycin affects the reaction [CALR protein affects the expression of BGLAP mRNA] CTD PMID:32220932 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G C5ar1 complement C5a receptor 1 increases expression ISO Ionomycin results in increased expression of C5AR1 protein CTD PMID:18559098 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression
EXP
ISO
Ionomycin inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]
Ionomycin results in increased expression of CALCA mRNA
[Ionomycin co-treated with Lipopolysaccharides] results in increased expression of CALCA protein; Ionomycin promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA]; Verapamil inhibits the reaction [[Ionomycin co-treated with Lipopolysaccharides] results in increased expression of CALCA protein]
Ionomycin results in increased expression of CALCA protein
CTD PMID:2470235 PMID:12574409 PMID:20682585 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calr calreticulin decreases response to substance
multiple interactions
ISO CALR protein results in decreased susceptibility to Ionomycin
Ionomycin affects the reaction [CALR protein affects the expression of ACAN mRNA]; Ionomycin affects the reaction [CALR protein affects the expression of BGLAP mRNA]; Ionomycin affects the reaction [CALR protein affects the expression of RUNX2 mRNA]; Ionomycin affects the reaction [CALR protein affects the expression of SOX9 mRNA]; Ionomycin affects the reaction [CALR protein affects the expression of SP7 mRNA]
CTD PMID:7961812 PMID:32220932 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP [Ionomycin co-treated with CAMK2A protein] inhibits the reaction [DRD3 protein promotes the reaction [Dopamine results in increased phosphorylation of MAPK1 protein]]; Ionomycin promotes the reaction [CAMK2A protein binds to ACTN1 protein]; Ionomycin promotes the reaction [CAMK2A protein binds to CDK5R1 protein]; Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]; Ionomycin promotes the reaction [CAMK2A protein binds to GRIN2B protein]; Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]] CTD PMID:19217379 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions ISO [Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein CTD PMID:33392831 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 multiple interactions ISO CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein] CTD PMID:12165276 PMID:29803841 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP8 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] CTD PMID:12165276 PMID:15477007 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL11 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein] CTD PMID:17572062 PMID:17685462 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL2 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein] CTD PMID:17572062 PMID:17685462 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] CTD PMID:15477007 PMID:17572062 PMID:17685462 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL4 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein] CTD PMID:17572062 PMID:17685462 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein] CTD PMID:17572062 PMID:17685462 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] CTD PMID:15477007 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] CTD PMID:15477007 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd200 Cd200 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] CTD PMID:15477007 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Cd40lg CD40 ligand multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG protein CTD PMID:22851303 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA CTD PMID:15477007 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Ionomycin results in increased expression of CD55 mRNA CTD PMID:24247028 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cd69 Cd69 molecule increases expression
multiple interactions
ISO Ionomycin results in increased expression of CD69 mRNA
[Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein
CTD PMID:23134680 PMID:24247028 PMID:26343699 PMID:30171972 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein CTD PMID:31958493 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule decreases expression
multiple interactions
ISO Ionomycin results in decreased expression of CD86 protein
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; PRKCB protein affects the reaction [[IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein]
CTD PMID:23376802 PMID:31958493 PMID:37326882 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdh17 cadherin 17 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] CTD PMID:15477007 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions EXP Ionomycin promotes the reaction [CAMK2A protein binds to CDK5R1 protein] CTD PMID:19217379 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO Egtazic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of and results in increased activity of CFL1 protein]; Ionomycin results in decreased phosphorylation of and results in increased activity of CFL1 protein CTD PMID:17303079 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity EXP Ionomycin results in increased activity of CFTR protein CTD PMID:15389550 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein; Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein] CTD PMID:10820281 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] CTD PMID:15477007 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein multiple interactions ISO CLN8 protein affects the reaction [[Ionomycin co-treated with Calcium] results in increased transport of D-Aspartic Acid] CTD PMID:22302580 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Col6a1 collagen type VI alpha 1 chain multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] CTD PMID:15477007 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA CTD PMID:15477007 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] CTD PMID:15477007 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in decreased expression of MIR146A mRNA; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of MIR27A mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CSF2 protein; PRKCB protein affects the reaction [[IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein] CTD PMID:17572062 PMID:17685462 PMID:37326882 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 multiple interactions ISO Ionomycin promotes the reaction [EGF protein promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]] CTD PMID:22317921 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] CTD PMID:15477007 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Cul5 cullin 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] CTD PMID:15477007 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 protein CTD PMID:9415701 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Ionomycin results in increased expression of DDIT3 protein CTD PMID:32578922 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] CTD PMID:10652249 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] CTD PMID:23775084 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DPYD mRNA CTD PMID:15705907 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions
increases phosphorylation
EXP [Ionomycin co-treated with CAMK2A protein] inhibits the reaction [DRD3 protein promotes the reaction [Dopamine results in increased phosphorylation of MAPK1 protein]]; Ionomycin inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol results in increased activity of DRD3 protein] which results in increased phosphorylation of MAPK1 protein]; Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]; Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin results in increased phosphorylation of DRD3 protein] CTD PMID:19217379 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] CTD PMID:15477007 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Ionomycin co-treated with EGF protein] results in increased phosphorylation of AKT1 protein; [Ionomycin co-treated with EGF protein] results in increased phosphorylation of MAPK1 protein; [Ionomycin co-treated with EGF protein] results in increased phosphorylation of MAPK3 protein; Ionomycin promotes the reaction [EGF protein promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]] CTD PMID:22317921 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein CTD PMID:12517959 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] CTD PMID:15477007 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO Ionomycin results in increased expression of EVI2A mRNA CTD PMID:24247028 NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
JBrowse link
G Faslg Fas ligand multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein; Tamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA] CTD PMID:20529085 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]
Ionomycin results in increased expression of FOS mRNA
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Ionomycin results in increased expression of FOS mRNA]
CTD PMID:9580328 PMID:9650640 PMID:15477007 PMID:15705907 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] CTD PMID:15477007 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Fyb1 FYN binding protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] CTD PMID:15477007 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA CTD PMID:22398747 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gfra2 GDNF family receptor alpha 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] CTD PMID:15477007 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
JBrowse link
G Gh1 growth hormone 1 increases secretion ISO Ionomycin results in increased secretion of GH1 protein CTD PMID:12471042 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP Ionomycin promotes the reaction [CAMK2A protein binds to GRIN2B protein] CTD PMID:19217379 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gzmb granzyme B multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein CTD PMID:30171972 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA CTD PMID:15477007 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] CTD PMID:15477007 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA CTD PMID:15477007 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion
multiple interactions
ISO
EXP
Ionomycin results in increased secretion of HEXB protein
Cyclosporine inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]; KN 93 inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]; ML 7 inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Ionomycin results in increased secretion of HEXB protein]
CTD PMID:14499669 PMID:19758318 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases activity
ISO Curcumin analog inhibits the reaction [Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; Curcumin analog inhibits the reaction [Ionomycin results in increased activity of HIF1A protein]; Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein] CTD PMID:20554536 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hk2 hexokinase 2 increases expression EXP Ionomycin results in increased expression of HK2 mRNA CTD PMID:17516843 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] CTD PMID:15477007 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions ISO HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] CTD PMID:19277450 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein] CTD PMID:10652249 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] CTD PMID:15477007 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Estradiol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Resveratrol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [2,4-diaminotoluene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Azathioprine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]
CTD PMID:12411406 PMID:12812920 PMID:15358692 PMID:15379866 PMID:15588918 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] CTD PMID:15477007 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; catechol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; quinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA
[Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; Genistein affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein]
CTD PMID:12884291 PMID:15588918 PMID:16716911 PMID:17572062 PMID:17685462 More... NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA] CTD PMID:22398747 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA; biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Genistein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; hexaconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; T0901317 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; tetraconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; triflumizol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]
[Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein
CTD PMID:22289359 PMID:25583575 PMID:27783946 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Ionomycin co-treated with IL1A protein] results in decreased secretion of IL4 protein; [Ionomycin co-treated with IL1A protein] results in increased secretion of IL6 protein; [Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein; [Ionomycin co-treated with IL1A protein] results in increased secretion of TNF protein; IL1A protein promotes the reaction [Ionomycin results in increased expression of IL9 mRNA]; IL1RN protein inhibits the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL3 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL6 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein] CTD PMID:10820229 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL1B protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein] CTD PMID:17572062 PMID:17685462 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO IL1RN protein inhibits the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein] CTD PMID:10820229 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression
ISO
EXP
[Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [bis(tri-n-butyltin)oxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Sodium Dodecyl Sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]
1-Butanol inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dexamethasone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [diethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Formaldehyde co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Isoniazid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [isophorone diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mitomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pyrimethamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Warfarin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Lenalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter]; norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; SB 203580 inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; tert-Butyl Alcohol inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; U 0126 inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Ionomycin results in increased expression of IL2 mRNA]
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]
CTD PMID:8658534 PMID:8662742 PMID:9439728 PMID:11592964 PMID:12165276 More... NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21 interleukin 21 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] CTD PMID:22077062 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha multiple interactions
increases secretion
ISO
EXP
[Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; Cyclosporine inhibits the reaction [Ionomycin results in increased secretion of IL2RA protein]; Sirolimus inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein]; Sirolimus inhibits the reaction [Ionomycin results in increased secretion of IL2RA protein]
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; tetrathiomolybdate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2RA protein
CTD PMID:8586487 PMID:9766631 PMID:22398747 PMID:23134680 PMID:26343699 More... NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il2rb interleukin 2 receptor subunit beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] CTD PMID:15477007 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il3 interleukin 3 multiple interactions ISO IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL3 protein] CTD PMID:10820229 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 multiple interactions ISO
EXP
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in decreased expression of MIR146A mRNA; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of MIR27A mRNA; [Ionomycin co-treated with IL1A protein] results in decreased secretion of IL4 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL3 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL6 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein]; PRKCB protein affects the reaction [[IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; Cyclosporine inhibits the reaction [IL4 protein promotes the reaction [Ionomycin results in increased expression of TNFRSF4 protein]]; IL4 protein promotes the reaction [Ionomycin results in increased expression of TNFRSF4 protein]; Staurosporine inhibits the reaction [IL4 protein promotes the reaction [Ionomycin results in increased expression of TNFRSF4 protein]]
[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Toluene 2,4-Diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]
CTD PMID:8658534 PMID:9766631 PMID:10820229 PMID:12709020 PMID:12884291 More... NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO
EXP
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]
CTD PMID:8658534 PMID:12884291 PMID:17475810 PMID:17572062 PMID:17685462 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; [Ionomycin co-treated with IL1A protein] results in increased secretion of IL6 protein; [Ionomycin co-treated with Lipopolysaccharides] results in increased expression of IL6 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL6 protein]; Ionomycin promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]
Ionomycin results in increased expression of IL6 mRNA
CTD PMID:10820229 PMID:12884291 PMID:17572062 PMID:17685462 PMID:18434080 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il9 interleukin 9 increases expression
multiple interactions
ISO Ionomycin results in increased expression of IL9 mRNA
[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein; IL1A protein promotes the reaction [Ionomycin results in increased expression of IL9 mRNA]; IL1RN protein inhibits the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein]; IL4 protein affects the reaction [[Ionomycin co-treated with IL1A protein] results in increased secretion of IL9 protein]
CTD PMID:10820229 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] CTD PMID:15477007 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Thiopental inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA] CTD PMID:9580328 PMID:15263067 PMID:15477007 PMID:15705907 PMID:25073960 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 multiple interactions
increases activity
EXP [Ionomycin results in increased activity of KCNN3 protein] which results in increased import of Thallium; Apamin inhibits the reaction [[Ionomycin results in increased activity of KCNN3 protein] which results in increased import of Thallium] CTD PMID:15634793 NCBI chr 2:174,929,846...175,088,910
Ensembl chr 2:174,936,629...175,081,145
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 multiple interactions ISO [Ionomycin co-treated with Tetraethylammonium] results in increased activity of KCNN4 protein; Clotrimazole inhibits the reaction [[Ionomycin co-treated with Tetraethylammonium] results in increased activity of KCNN4 protein] CTD PMID:14985237 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] CTD PMID:15477007 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] CTD PMID:15477007 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] CTD PMID:17615583 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein] CTD PMID:15263067 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression ISO Ionomycin results in increased expression of LAMP1 protein CTD PMID:23376802 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA CTD PMID:15477007 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] CTD PMID:15477007 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP Ionomycin inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] CTD PMID:12574409 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
1-Butanol inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [Ionomycin co-treated with EGF protein] results in increased phosphorylation of MAPK1 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]
[Ionomycin co-treated with CAMK2A protein] inhibits the reaction [DRD3 protein promotes the reaction [Dopamine results in increased phosphorylation of MAPK1 protein]]; Ionomycin inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol results in increased activity of DRD3 protein] which results in increased phosphorylation of MAPK1 protein]; Ionomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:15477007 PMID:16877402 PMID:18423386 PMID:19217379 PMID:22317921 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
[Ionomycin co-treated with EGF protein] results in increased phosphorylation of MAPK3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Ionomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:15477007 PMID:16877402 PMID:18423386 PMID:22317921 PMID:23134680 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein] CTD PMID:25073960 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapt microtubule-associated protein tau decreases phosphorylation
multiple interactions
ISO
EXP
Ionomycin results in decreased phosphorylation of MAPT protein
Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein]
CTD PMID:9200503 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mir146a microRNA 146a multiple interactions ISO [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in decreased expression of MIR146A mRNA CTD PMID:37326882 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir27a microRNA 27a multiple interactions ISO [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of MIR27A mRNA CTD PMID:37326882 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA] CTD PMID:15477007 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions
EXP Ionomycin results in increased phosphorylation of MYL9 protein
Trifluoperazine inhibits the reaction [Ionomycin results in increased phosphorylation of MYL9 protein]
CTD PMID:19233221 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA CTD PMID:15477007 NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563
JBrowse link
G Ncs1 neuronal calcium sensor 1 increases response to substance EXP NCS1 protein results in increased susceptibility to Ionomycin CTD PMID:12471042 NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829
JBrowse link
G Nell1 neural EGFL like 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA CTD PMID:15477007 NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions
decreases phosphorylation
ISO Hydrogen Peroxide inhibits the reaction [Ionomycin results in decreased phosphorylation of NFATC1 protein] CTD PMID:12203019 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein; Acetic Acid inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of and results in decreased phosphorylation of NFATC2 protein; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]
CTD PMID:17615583 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions
affects localization
ISO
EXP
[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]
Ionomycin affects the localization of NFATC3 protein
CTD PMID:12709020 PMID:15799720 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases localization EXP Ionomycin results in increased localization of NFATC4 protein CTD PMID:16849427 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases response to substance
multiple interactions
decreases response to substance
ISO NFE2L2 gene mutant form results in increased susceptibility to Ionomycin
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFE2L2 protein
NFE2L2 protein results in decreased susceptibility to Ionomycin
CTD PMID:12842875 PMID:24632381 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein] CTD PMID:15477007 PMID:25073960 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nkg7 natural killer cell granule protein 7 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] CTD PMID:15477007 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Nmi N-myc (and STAT) interactor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA CTD PMID:15477007 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
JBrowse link
G Notch3 notch receptor 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] CTD PMID:15477007 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA CTD PMID:15477007 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP PLCB1 protein promotes the reaction [Ionomycin results in increased abundance of Inositol Phosphates] CTD PMID:11377826 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Pld2 phospholipase D2 multiple interactions ISO PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:18423386 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Ionomycin results in increased expression of PMAIP1 mRNA CTD PMID:24247028 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] CTD PMID:15477007 NCBI chr  X:42,313,554...42,318,451
Ensembl chr  X:42,305,373...42,318,552
JBrowse link
G Pou2f1 POU class 2 homeobox 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of POU2F1 protein CTD PMID:16241859 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363
JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] CTD PMID:15477007 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
increases expression
EXP Cyclosporine inhibits the reaction [Ionomycin results in increased expression of PPARGC1A mRNA]; KN 62 affects the reaction [Ionomycin results in increased expression of PPARGC1A mRNA] CTD PMID:17516843 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions ISO PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] CTD PMID:23775084 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta multiple interactions ISO PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] CTD PMID:23775084 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Prf1 perforin 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein CTD PMID:30171972 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO PRKCB protein affects the reaction [[IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein] CTD PMID:37326882 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcq protein kinase C, theta multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein] CTD PMID:16241859 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] CTD PMID:22398747 NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] CTD PMID:22398747 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions EXP Ionomycin results in increased phosphorylation of and results in increased activity of PTK2B protein CTD PMID:16877402 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of RBPJ protein CTD PMID:23134680 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO Ionomycin results in increased expression of RCAN1 protein CTD PMID:12927602 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA] CTD PMID:15477007 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rhog ras homolog family member G multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] CTD PMID:15477007 NCBI chr 1:156,618,713...156,630,710
Ensembl chr 1:156,615,349...156,631,257
JBrowse link
G Rnaset2 ribonuclease T2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] CTD PMID:15477007 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147
JBrowse link
G RT1-Da RT1 class II, locus Da multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RT1-DA protein CTD PMID:9536116 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO Ionomycin affects the reaction [CALR protein affects the expression of RUNX2 mRNA] CTD PMID:32220932 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] CTD PMID:15477007 NCBI chr 1:202,690,472...202,699,136
Ensembl chr 1:202,690,459...202,699,136
JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP Ionomycin results in increased expression of SERPINE1 mRNA CTD PMID:15961275 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sf3b4 splicing factor 3B subunit 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] CTD PMID:15477007 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
JBrowse link
G Sftpb surfactant protein B increases secretion ISO
EXP
Ionomycin results in increased secretion of SFTPB protein CTD PMID:11704537 PMID:14565945 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpc surfactant protein C increases secretion ISO
EXP
Ionomycin results in increased secretion of SFTPC protein CTD PMID:11704537 PMID:14565945 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sirt1 sirtuin 1 increases expression EXP Ionomycin results in increased expression of SIRT1 protein CTD PMID:17581637 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sla src-like adaptor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] CTD PMID:15477007 NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
JBrowse link
G Slc39a7 solute carrier family 39 member 7 multiple interactions ISO Ionomycin promotes the reaction [EGF protein promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]] CTD PMID:22317921 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] CTD PMID:15477007 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] CTD PMID:22429591 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions ISO Ionomycin affects the reaction [CALR protein affects the expression of SOX9 mRNA] CTD PMID:32220932 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Ionomycin affects the reaction [CALR protein affects the expression of SP7 mRNA] CTD PMID:32220932 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Srpra SRP receptor subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA CTD PMID:15477007 NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470
JBrowse link
G Stim1 stromal interaction molecule 1 multiple interactions ISO [Thapsigargin co-treated with Ionomycin] promotes the reaction [STIM1 protein binds to ATP2A3 protein] CTD PMID:18439569 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions
increases phosphorylation
ISO STO 609 inhibits the reaction [Ionomycin results in increased phosphorylation of STK11 protein] CTD PMID:33124469 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Syn1 synapsin I affects response to substance ISO SYN1 protein affects the susceptibility to Ionomycin CTD PMID:22759588 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA] CTD PMID:22398747 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tfrc transferrin receptor multiple interactions EXP [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TFRC protein CTD PMID:9766631 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGFB1 mRNA CTD PMID:18434080 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in decreased expression of MIR146A mRNA; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of MIR27A mRNA; [Ionomycin co-treated with IL1A protein] results in increased secretion of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Ionomycin inhibits the reaction [[N-(4-hydroxyphenyl)arachidonylamide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; PRKCB protein affects the reaction [[IL4 protein co-treated with CSF2 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA]
CTD PMID:10820229 PMID:10890505 PMID:12411406 PMID:15358692 PMID:16154495 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA CTD PMID:15477007 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 multiple interactions
increases expression
EXP Cyclosporine inhibits the reaction [IL4 protein promotes the reaction [Ionomycin results in increased expression of TNFRSF4 protein]]; Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Cyclosporine inhibits the reaction [Ionomycin results in increased expression of TNFRSF4 protein]; IL4 protein promotes the reaction [Ionomycin results in increased expression of TNFRSF4 protein]; Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Staurosporine inhibits the reaction [IL4 protein promotes the reaction [Ionomycin results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]] CTD PMID:9766631 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
JBrowse link
G Tnfsf9 TNF superfamily member 9 multiple interactions ISO [Ionomycin co-treated with Phorbol Esters] promotes the reaction [entinostat results in increased expression of TNFSF9 mRNA]; [Ionomycin co-treated with Phorbol Esters] promotes the reaction [trichostatin A results in increased expression of TNFSF9 mRNA]; [Ionomycin co-treated with Phorbol Esters] promotes the reaction [vorinostat results in increased expression of TNFSF9 mRNA] CTD PMID:19759901 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
G Tnpo1 transportin 1 increases expression ISO Ionomycin results in increased expression of TNPO1 mRNA CTD PMID:10843682 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA] CTD PMID:15477007 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] CTD PMID:15477007 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions
increases activity
ISO [Ionomycin co-treated with Calcium co-treated with CAMK2D protein] results in increased activity of TRPM4 protein
Ionomycin results in increased activity of TRPM4 protein
CTD PMID:25047048 PMID:33392831 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO
EXP
Ionomycin promotes the reaction [Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]]
Ionomycin results in increased activity of TRPV1 protein
Ionomycin inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; Ionomycin inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]
CTD PMID:11606325 PMID:19553475 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity EXP Ionomycin results in increased activity of TRPV3 protein CTD PMID:21726418 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases activity EXP Ionomycin results in increased activity of TRPV4 protein CTD PMID:21726418 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Ionomycin results in decreased expression of TXNIP mRNA CTD PMID:10843682 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] CTD PMID:15477007 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
G Vim vimentin multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA CTD PMID:15477007 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [deoxynivalenol results in decreased expression of ZEB1 protein] CTD PMID:11893416 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
lasalocid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta increases expression ISO Lasalocid results in increased expression of ACTB protein CTD PMID:37788135 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Anxa1 annexin A1 increases expression ISO Lasalocid results in increased expression of ANXA1 protein CTD PMID:37788135 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 increases expression ISO Lasalocid results in increased expression of ANXA2 protein CTD PMID:37788135 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Dsp desmoplakin increases expression ISO Lasalocid results in increased expression of DSP protein CTD PMID:37788135 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO Lasalocid results in increased expression of HNRNPA1 protein CTD PMID:37788135 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression ISO Lasalocid results in increased expression of HNRNPA2B1 protein CTD PMID:37788135 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Lasalocid results in increased expression of HSPB1 protein CTD PMID:37788135 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Ivl involucrin increases expression ISO Lasalocid results in increased expression of IVL protein CTD PMID:37788135 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jup junction plakoglobin increases expression ISO Lasalocid results in increased expression of JUP protein CTD PMID:37788135 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Krt5 keratin 5 increases expression ISO Lasalocid results in increased expression of KRT5 protein CTD PMID:37788135 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Lasalocid results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Pkp1 plakophilin 1 increases expression ISO Lasalocid results in increased expression of PKP1 protein CTD PMID:37788135 NCBI chr13:47,309,607...47,357,432
Ensembl chr13:47,309,614...47,357,465
JBrowse link
G Ppl periplakin increases expression ISO Lasalocid results in increased expression of PPL protein CTD PMID:37788135 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO Lasalocid results in increased expression of S100A10 protein CTD PMID:37788135 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO Lasalocid results in increased expression of S100A11 protein CTD PMID:37788135 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G S100a16 S100 calcium binding protein A16 increases expression ISO Lasalocid results in increased expression of S100A16 protein CTD PMID:37788135 NCBI chr 2:176,016,405...176,022,117
Ensembl chr 2:176,016,268...176,022,117
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Lasalocid results in increased expression of SERPINB2 protein CTD PMID:37788135 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO Lasalocid results in increased expression of SPRR1A protein CTD PMID:37788135 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Lasalocid results in increased expression of SPRR1B protein CTD PMID:37788135 NCBI chr 2:178,008,844...178,010,742
Ensembl chr 2:178,009,130...178,009,567
JBrowse link
G Sprr2d small proline-rich protein 2D increases expression ISO Lasalocid results in increased expression of SPRR2D protein CTD PMID:37788135 NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679
JBrowse link
monensin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40)]; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42)]
Monensin inhibits the reaction [Ketamine results in decreased expression of and results in increased cleavage of APP protein]
CTD PMID:35378374 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO Monensin inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO Monensin inhibits the reaction [Ketamine results in increased expression of and affects the localization of BACE1 protein] CTD PMID:35378374 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Monensin results in increased expression of BNIP3 protein CTD PMID:30718715 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Lithium inhibits the reaction [Monensin results in increased activity of CASP3 protein] CTD PMID:20799912 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO Lithium inhibits the reaction [Monensin results in increased activity of CASP7 protein] CTD PMID:20799912 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Monensin inhibits the reaction [kaempferol results in increased secretion of CSF2 protein]; Monensin inhibits the reaction [Quercetin results in increased secretion of CSF2 protein] CTD PMID:18346843 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [EGF protein co-treated with Monensin] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Il6 interleukin 6 decreases secretion ISO Monensin results in decreased secretion of IL6 protein CTD PMID:11216681 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 decreases degradation EXP Monensin results in decreased degradation of INS1 protein CTD PMID:2645939 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP [EGF protein co-treated with Monensin] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Monensin results in increased cleavage of PARP1 protein CTD PMID:30718715 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Slc6a2 solute carrier family 6 member 2 multiple interactions ISO Monensin promotes the reaction [para-methyl-4-methylaminorex inhibits the reaction [SLC6A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]] CTD PMID:29908239 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Monensin promotes the reaction [para-methyl-4-methylaminorex inhibits the reaction [SLC6A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]] CTD PMID:29908239 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions ISO Monensin promotes the reaction [para-methyl-4-methylaminorex inhibits the reaction [SLC6A4 protein results in increased uptake of Serotonin]] CTD PMID:29908239 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 decreases expression
increases expression
multiple interactions
ISO Monensin results in decreased expression of TRPM2 protein alternative form
Monensin results in increased expression of TRPM2 protein alternative form
Lithium inhibits the reaction [Monensin results in increased expression of TRPM2 protein alternative form]
CTD PMID:20799912 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 increases response to substance ISO ZEB1 protein results in increased susceptibility to Monensin CTD PMID:30718715 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
nicotianamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO nicotianamine results in decreased activity of ACE protein CTD PMID:26106051 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases activity ISO nicotianamine results in decreased activity of ACE2 protein CTD PMID:26106051 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
nigericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp9 aquaporin 9 multiple interactions ISO Nigericin inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Nigericin inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] CTD PMID:28798983 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Casp1 caspase 1 multiple interactions
increases cleavage
ISO
EXP
[Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; CASP1 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]
Nigericin inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased cleavage of CASP1 protein]]
Nigericin results in increased cleavage of CASP1 protein
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Nigericin] results in increased cleavage of CASP1 protein; [Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of CASP1 protein; Arsenic Trioxide inhibits the reaction [Nigericin results in increased cleavage of CASP1 protein]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of CASP1 protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Nigericin] results in increased cleavage of CASP1 protein]; sodium arsenite inhibits the reaction [Nigericin results in increased cleavage of CASP1 protein]
CTD PMID:18403674 PMID:23430110 PMID:24337744 PMID:36002070 PMID:36577999 More... NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions ISO Nigericin promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO
EXP
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Nigericin] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of GSDMD protein; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of GSDMD protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Nigericin] results in increased cleavage of GSDMD protein]
Nigericin inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased cleavage of GSDMD protein]]
CTD PMID:36002070 PMID:36577999 PMID:36898572 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
increases cleavage
ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Nigericin] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Nigericin] results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein; Arsenic Trioxide inhibits the reaction [Nigericin results in increased cleavage of IL1B protein]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of IL1B protein]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Nigericin] results in increased secretion of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein]; Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased expression of IL1B protein]; sodium arsenite inhibits the reaction [Nigericin results in increased cleavage of IL1B protein]
Nigericin results in increased secretion of IL1B protein
[Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B protein; CASP1 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [Nigericin results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [Nigericin results in increased secretion of IL1B protein]
CTD PMID:18403674 PMID:19130485 PMID:23430110 PMID:24337744 PMID:29642561 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO
EXP
NLRP3 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]
Nigericin inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein]]
CTD PMID:18403674 PMID:36898572 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nnat neuronatin decreases response to substance EXP NNAT protein results in decreased susceptibility to Nigericin CTD PMID:12101027 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO
EXP
PYCARD protein affects the reaction [Nigericin results in increased secretion of IL1B protein]
Nigericin inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased expression of PYCARD protein]]
CTD PMID:18403674 PMID:36898572 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Nigericin results in decreased expression of STAR protein CTD PMID:16469751 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Lipopolysaccharides co-treated with Nigericin] results in increased expression of TNF protein CTD PMID:23430110 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
okadaic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase decreases activity
decreases expression
EXP Okadaic Acid results in decreased activity of AANAT protein
Okadaic Acid results in decreased expression of AANAT mRNA
CTD PMID:11442772 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
increases expression
ISO ABCB1 protein results in increased transport of Okadaic Acid
Okadaic Acid results in increased expression of ABCB1 mRNA
CTD PMID:24374049 PMID:31926150 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases response to substance EXP ABCB1B protein results in decreased susceptibility to Okadaic Acid CTD PMID:10494879 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO Okadaic Acid results in decreased expression of ABCC3 mRNA CTD PMID:31926150 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Okadaic Acid results in increased expression of ABCG2 mRNA CTD PMID:31926150 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ABL1 mRNA CTD PMID:19840844 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Aco1 aconitase 1 multiple interactions EXP Okadaic Acid inhibits the reaction [EGF protein results in decreased activity of ACO1 protein]; Okadaic Acid inhibits the reaction [TRH protein results in decreased activity of ACO1 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein] CTD PMID:10889193 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Acox2 acyl-CoA oxidase 2 increases expression ISO Okadaic Acid results in increased expression of ACOX2 mRNA CTD PMID:25270620 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Agt angiotensinogen multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of AGT mRNA CTD PMID:19840844 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
Okadaic Acid inhibits the reaction [Amiloride results in decreased phosphorylation of AKT1 protein]; Okadaic Acid inhibits the reaction [arsenic trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]]; Okadaic Acid inhibits the reaction [arsenic trioxide results in decreased phosphorylation of AKT1 protein]; Okadaic Acid inhibits the reaction [Bortezomib results in decreased expression of AKT1 protein modified form]
Okadaic Acid results in increased phosphorylation of AKT1 protein
Okadaic Acid results in decreased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid results in decreased phosphorylation of AKT1 protein]]; Quercetin inhibits the reaction [Okadaic Acid results in decreased phosphorylation of AKT1 protein]
CTD PMID:16059913 PMID:19261616 PMID:21655183 PMID:26437446 PMID:27050422 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of ALDH1A1 mRNA CTD PMID:19840844 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases phosphorylation ISO Okadaic Acid results in increased phosphorylation of ALDH1L1 protein CTD PMID:18000846 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO Okadaic Acid results in decreased expression of ALDOA protein CTD PMID:19397276 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 decreases expression ISO Okadaic Acid results in decreased expression of ANAPC13 mRNA CTD PMID:23561263 NCBI chr 8:103,205,520...103,213,936
Ensembl chr 8:103,205,520...103,213,936
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ANXA5 mRNA CTD PMID:19840844 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Okadaic Acid results in increased expression of APAF1 mRNA CTD PMID:31926150 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apobr apolipoprotein B receptor increases expression ISO Okadaic Acid results in increased expression of APOBR mRNA CTD PMID:25270620 NCBI chr 1:181,169,019...181,173,206
Ensembl chr 1:181,168,916...181,173,528
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of APP mRNA CTD PMID:19840844 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arhgef17 Rho guanine nucleotide exchange factor 17 multiple interactions ISO [calyculin A co-treated with Okadaic Acid] inhibits the reaction [2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]] CTD PMID:23195829 NCBI chr 1:155,230,607...155,290,163
Ensembl chr 1:155,233,168...155,290,498
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO Okadaic Acid results in increased expression of ARNT mRNA CTD PMID:28939011 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression ISO Okadaic Acid results in decreased expression of ATP5F1A protein CTD PMID:19397276 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta multiple interactions
decreases expression
ISO [Okadaic Acid co-treated with gambierol] results in increased expression of ATP5F1D protein
Okadaic Acid results in decreased expression of ATP5F1D protein
CTD PMID:19397276 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atxn3 ataxin 3 increases expression ISO Okadaic Acid results in increased expression of ATXN3 mRNA CTD PMID:28939011 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Axin2 axin 2 increases expression ISO Okadaic Acid results in increased expression of AXIN2 mRNA CTD PMID:31115591 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO Okadaic Acid results in decreased expression of BAD mRNA CTD PMID:31926150 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Okadaic Acid results in increased expression of BAK1 mRNA CTD PMID:31926150 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
multiple interactions
increases expression
decreases expression
ISO
EXP
Okadaic Acid affects the localization of BAX protein
Quercetin inhibits the reaction [Okadaic Acid results in increased expression of BAX protein]
Okadaic Acid results in decreased expression of BAX protein
Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased expression of BAX protein]
Okadaic Acid results in increased cleavage of and results in increased activity of BAX protein
CTD PMID:10510466 PMID:18937299 PMID:19084044 PMID:27050422 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
affects response to substance
ISO Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]; Okadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]; Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]
BBC3 protein affects the susceptibility to Okadaic Acid
CTD PMID:20477944 PMID:24954032 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BCAT2 mRNA CTD PMID:19840844 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha decreases expression ISO Okadaic Acid results in decreased expression of BCKDHA mRNA CTD PMID:25270620 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
ISO Okadaic Acid results in decreased expression of BCL2 protein
Okadaic Acid results in increased expression of BCL2 mRNA
CTD PMID:18937299 PMID:31926150 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO Okadaic Acid results in increased expression of BCL2L11 mRNA CTD PMID:28939011 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l14 Bcl2-like 14 increases expression ISO Okadaic Acid results in increased expression of BCL2L14 mRNA CTD PMID:25270620 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bgn biglycan multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of BGN mRNA CTD PMID:19840844 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Okadaic Acid results in increased expression of BIRC5 mRNA CTD PMID:31115591 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blvrb biliverdin reductase B multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BLVRB mRNA CTD PMID:19840844 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO Okadaic Acid results in increased expression of BPGM mRNA CTD PMID:28939011 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
JBrowse link
G Cacybp calcyclin binding protein decreases expression ISO Okadaic Acid results in decreased expression of CACYBP protein CTD PMID:19397276 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CALM1 mRNA CTD PMID:19840844 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Okadaic Acid results in decreased expression of CALM2 mRNA CTD PMID:23561263 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calr calreticulin increases expression ISO Okadaic Acid results in increased expression of CALR mRNA CTD PMID:28939011 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Canx calnexin increases expression ISO Okadaic Acid results in increased expression of CANX mRNA CTD PMID:28939011 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Car13 carbonic anhydrase 13 increases expression ISO Okadaic Acid results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
EXP
ISO
Norepinephrine inhibits the reaction [Okadaic Acid results in increased activity of CASP3 protein]
Okadaic Acid results in increased expression of CASP3 mRNA; Okadaic Acid results in increased expression of CASP3 protein modified form
Quercetin inhibits the reaction [Okadaic Acid results in increased cleavage of CASP3 protein]
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Okadaic Acid results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Okadaic Acid results in increased cleavage of and results in increased activity of CASP3 protein]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; Okadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]]; Okadaic Acid results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:11099166 PMID:16954443 PMID:19084044 PMID:23288922 PMID:23335626 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Okadaic Acid results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:19084044 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression
increases activity
increases expression
ISO acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Okadaic Acid results in increased cleavage of and results in increased activity of CASP8 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Okadaic Acid results in increased cleavage of and results in increased activity of CASP8 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP8 protein]; Okadaic Acid results in increased cleavage of and results in increased activity of CASP8 protein
Okadaic Acid results in decreased expression of CASP8 mRNA
Okadaic Acid results in increased activity of CASP8 protein
Okadaic Acid results in increased expression of CASP8 protein modified form
CTD PMID:19084044 PMID:23288922 PMID:31926150 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO
EXP
Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP9 protein]; Okadaic Acid results in increased cleavage of and results in increased activity of CASP9 protein
Okadaic Acid results in increased expression of CASP9 mRNA; Okadaic Acid results in increased expression of CASP9 protein modified form
Okadaic Acid results in increased activity of CASP9 protein
CTD PMID:19084044 PMID:23288922 PMID:26732598 PMID:31926150 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression
decreases activity
ISO Okadaic Acid results in decreased expression of CAT mRNA
Okadaic Acid results in decreased activity of CAT protein
CTD PMID:35577138 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbx1 chromobox 1 increases expression ISO Okadaic Acid results in increased expression of CBX1 mRNA CTD PMID:25270620 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of and results in increased secretion of CCL2 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid] results in increased expression of and results in increased secretion of CCL2 protein CTD PMID:33069748 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 increases expression ISO Okadaic Acid results in increased expression of CCL25 mRNA CTD PMID:25270620 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554
JBrowse link
G Ccna1 cyclin A1 affects expression ISO Okadaic Acid affects the expression of CCNA1 mRNA CTD PMID:21512803 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnb2 cyclin B2 affects expression ISO Okadaic Acid affects the expression of CCNB2 mRNA CTD PMID:21512803 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Okadaic Acid results in increased expression of CCND1 mRNA CTD PMID:31115591 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression ISO Okadaic Acid results in increased expression of CCT4 mRNA CTD PMID:28939011 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression ISO Okadaic Acid results in increased expression of CCT7 mRNA CTD PMID:28939011 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cd44 CD44 molecule increases expression ISO Okadaic Acid results in increased expression of CD44 mRNA CTD PMID:28939011 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd9 CD9 molecule multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CD9 mRNA CTD PMID:19840844 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Okadaic Acid promotes the reaction [CTNNB1 protein binds to CDH1 protein] CTD PMID:31115591 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Okadaic Acid results in decreased expression of CDK1 mRNA CTD PMID:21512803 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Okadaic Acid results in decreased expression of CDK2 mRNA CTD PMID:21512803 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Okadaic Acid results in increased expression of CEBPB mRNA CTD PMID:28939011 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO Okadaic Acid results in decreased expression of CES1D mRNA CTD PMID:25270620 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Cfap251 cilia and flagella associated protein 251 decreases expression ISO Okadaic Acid results in decreased expression of CFAP251 mRNA CTD PMID:25270620 NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932
JBrowse link
G Cfl1 cofilin 1 increases expression ISO Okadaic Acid results in increased expression of CFL1 protein CTD PMID:19397276 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cftr CF transmembrane conductance regulator decreases activity ISO Okadaic Acid results in decreased activity of CFTR protein CTD PMID:15936019 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 decreases expression ISO Okadaic Acid results in decreased expression of CHCHD3 protein CTD PMID:19397276 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in decreased susceptibility to Okadaic Acid]; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in decreased susceptibility to Okadaic Acid; JAK2 protein affects the reaction [[PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in decreased susceptibility to Okadaic Acid] CTD PMID:21715663 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid] CTD PMID:21715663 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cldn2 claudin 2 increases expression ISO Okadaic Acid results in increased expression of CLDN2 mRNA CTD PMID:30926360 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cldn4 claudin 4 increases expression ISO Okadaic Acid results in increased expression of CLDN4 mRNA CTD PMID:30926360 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cldn7 claudin 7 increases expression ISO Okadaic Acid results in increased expression of CLDN7 mRNA CTD PMID:30926360 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Clns1a chloride nucleotide-sensitive channel 1A decreases expression ISO Okadaic Acid results in decreased expression of CLNS1A protein CTD PMID:19397276 NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661
JBrowse link
G Clta clathrin, light chain A multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CLTA mRNA CTD PMID:19840844 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
JBrowse link
G Clu clusterin increases expression ISO Okadaic Acid results in increased expression of CLU mRNA CTD PMID:23561263 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Okadaic Acid results in increased expression of COL1A1 mRNA CTD PMID:8997264 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL1A2 mRNA CTD PMID:19840844 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col6a1 collagen type VI alpha 1 chain multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL6A1 mRNA CTD PMID:19840844 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL8A1 mRNA CTD PMID:19840844 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
JBrowse link
G Comt catechol-O-methyltransferase decreases expression
multiple interactions
ISO Okadaic Acid results in decreased expression of COMT protein
[Okadaic Acid co-treated with gambierol] results in decreased expression of COMT protein
CTD PMID:19397276 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coq3 coenzyme Q3 methyltransferase increases expression ISO Okadaic Acid results in increased expression of COQ3 mRNA CTD PMID:25270620 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Cpne9 copine family member 9 decreases expression ISO Okadaic Acid results in decreased expression of CPNE9 mRNA CTD PMID:25270620 NCBI chr 4:146,429,961...146,454,335
Ensembl chr 4:146,430,792...146,454,333
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP
ISO
Okadaic Acid inhibits the reaction [resveratrol inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]]
Okadaic Acid inhibits the reaction [Daunorubicin results in decreased phosphorylation of CREB1 protein]
CTD PMID:23292070 PMID:34963561 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein increases phosphorylation
increases expression
ISO Okadaic Acid results in increased phosphorylation of CREBBP protein
Okadaic Acid results in increased expression of CREBBP mRNA
CTD PMID:16059639 PMID:28939011 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Ctnnb1 catenin beta 1 increases phosphorylation
increases expression
multiple interactions
ISO Okadaic Acid results in increased phosphorylation of CTNNB1 protein
Okadaic Acid results in increased expression of CTNNB1 mRNA
Okadaic Acid promotes the reaction [CTNNB1 protein binds to CDH1 protein]; Okadaic Acid promotes the reaction [CTNNB1 protein binds to CTNNBIP1 protein]; Okadaic Acid promotes the reaction [CTNNB1 protein binds to TCF4 protein]; Okadaic Acid results in increased activity of and results in decreased phosphorylation of CTNNB1 protein; Okadaic Acid results in increased expression of and affects the localization of CTNNB1 protein
CTD PMID:16878161 PMID:31115591 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 multiple interactions ISO Okadaic Acid promotes the reaction [CTNNB1 protein binds to CTNNBIP1 protein] CTD PMID:31115591 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
JBrowse link
G Ctsb cathepsin B multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of CTSB mRNA CTD PMID:19840844 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CTSL mRNA CTD PMID:19840844 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA CTD PMID:19840844 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP
ISO
CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Okadaic Acid CTD PMID:26374342 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Okadaic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:10696073 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP Okadaic Acid inhibits the reaction [2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of CYP2B1 protein]; Okadaic Acid inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP2B1 protein]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP2B1 protein]; Okadaic Acid inhibits the reaction [2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP2B1 protein]; Okadaic Acid inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP2B1 protein]; Okadaic Acid inhibits the reaction [PCB 180 results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [PCB 180 results in increased expression of CYP2B1 protein]; Okadaic Acid inhibits the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA]; Okadaic Acid inhibits the reaction [Phenobarbital results in increased expression of CYP2B1 protein] CTD PMID:23770461 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Okadaic Acid inhibits the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA] CTD PMID:27832320 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO Okadaic Acid results in decreased expression of CYP2C29 mRNA CTD PMID:25270620 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO Okadaic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:25270620 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases response to substance
EXP
ISO
CYP3A2 protein results in increased metabolism of and results in increased hydroxylation of and results in increased susceptibility to Okadaic Acid
CYP3A4 protein results in increased metabolism of and results in increased hydroxylation of and results in decreased susceptibility to Okadaic Acid
CYP3A4 protein results in decreased susceptibility to Okadaic Acid
CTD PMID:24504163 PMID:26374342 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP CYP3A23-3A1 protein results in increased metabolism of and results in increased hydroxylation of and results in decreased susceptibility to Okadaic Acid; Okadaic Acid inhibits the reaction [2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of CYP3A23-3A1 protein]; Okadaic Acid inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP3A23-3A1 protein]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP3A23-3A1 protein]; Okadaic Acid inhibits the reaction [2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP3A23-3A1 protein]; Okadaic Acid inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP3A23-3A1 protein]; Okadaic Acid inhibits the reaction [PCB 180 results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [PCB 180 results in increased expression of CYP3A23-3A1 protein]; Okadaic Acid inhibits the reaction [Phenobarbital results in increased expression of CYP3A23-3A1 mRNA]; Okadaic Acid inhibits the reaction [Phenobarbital results in increased expression of CYP3A23-3A1 protein] CTD PMID:23770461 PMID:26374342 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 protein results in increased metabolism of and results in increased hydroxylation of and results in decreased susceptibility to Okadaic Acid CTD PMID:26374342 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions EXP Okadaic Acid inhibits the reaction [Dehydroepiandrosterone results in increased expression of CYP4A1 mRNA]; Okadaic Acid inhibits the reaction [Nafenopin results in increased expression of CYP4A1 mRNA] CTD PMID:18079279 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO Okadaic Acid promotes the reaction [Calcitriol results in decreased expression of CYP7A1 mRNA]; Okadaic Acid promotes the reaction [lithocholic acid acetate results in decreased expression of CYP7A1 mRNA] CTD PMID:20371703 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dab2 DAB adaptor protein 2 affects phosphorylation ISO Okadaic Acid affects the phosphorylation of DAB2 protein CTD PMID:12881709 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Okadaic Acid results in increased expression of DDIT3 mRNA CTD PMID:28939011 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx1 DEAD-box helicase 1 increases expression ISO Okadaic Acid results in increased expression of DDX1 mRNA CTD PMID:28939011 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO Okadaic Acid results in decreased expression of DDX17 protein CTD PMID:19397276 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 decreases expression ISO Okadaic Acid results in decreased expression of DHTKD1 mRNA CTD PMID:25270620 NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression ISO Okadaic Acid results in increased expression of DLAT mRNA CTD PMID:28939011 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of DLG1 mRNA CTD PMID:19840844 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO Okadaic Acid results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 increases expression ISO Okadaic Acid results in increased expression of DNAJB2 mRNA CTD PMID:28939011 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression ISO Okadaic Acid results in increased expression of DNAJC10 mRNA CTD PMID:28939011 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 decreases expression ISO Okadaic Acid results in decreased expression of DNAJC4 mRNA CTD PMID:28939011 NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
JBrowse link
G Dnm1l dynamin 1-like increases phosphorylation EXP Okadaic Acid results in increased phosphorylation of DNM1L protein CTD PMID:26732598 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] CTD PMID:23775084 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dsp desmoplakin increases expression ISO Okadaic Acid results in increased expression of DSP mRNA CTD PMID:25270620 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Dstn destrin, actin depolymerizing factor decreases expression ISO Okadaic Acid results in decreased expression of DSTN protein CTD PMID:19397276 NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
JBrowse link
G Egf epidermal growth factor multiple interactions EXP Okadaic Acid inhibits the reaction [EGF protein results in decreased activity of ACO1 protein]; Okadaic Acid inhibits the reaction [EGF protein results in decreased activity of IREB2 protein] CTD PMID:10889193 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression ISO Okadaic Acid results in increased expression of EGLN1 mRNA CTD PMID:28939011 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO Okadaic Acid results in increased expression of EGLN3 mRNA CTD PMID:28939011 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression ISO Okadaic Acid results in increased expression of EGR1 mRNA CTD PMID:28939011 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Okadaic Acid results in increased phosphorylation of EIF2S1 protein CTD PMID:26732598 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eln elastin multiple interactions
decreases expression
EXP [IL1B protein co-treated with Okadaic Acid] results in decreased expression of ELN mRNA; [Okadaic Acid co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ELN mRNA; Cycloheximide inhibits the reaction [Okadaic Acid results in decreased expression of ELN mRNA]
Okadaic Acid results in decreased expression of ELN mRNA; Okadaic Acid results in decreased expression of ELN protein modified form
CTD PMID:8997264 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Elob elongin B increases expression ISO Okadaic Acid results in increased expression of ELOB mRNA CTD PMID:28939011 NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
JBrowse link
G Eloc elongin C increases expression ISO Okadaic Acid results in increased expression of ELOC mRNA CTD PMID:28939011 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO Okadaic Acid results in decreased expression of EP300 mRNA CTD PMID:28939011 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Okadaic Acid results in increased expression of EPAS1 mRNA CTD PMID:28939011 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epha5 EPH receptor A5 increases expression ISO Okadaic Acid results in increased expression of EPHA5 mRNA CTD PMID:25270620 NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Okadaic Acid results in increased expression of ERN1 mRNA CTD PMID:28939011 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Okadaic Acid results in increased expression of ERO1A protein CTD PMID:26732598 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Okadaic Acid results in increased degradation of ESR1 mRNA]; Okadaic Acid inhibits the reaction [Linoleic Acids, Conjugated results in decreased phosphorylation of ESR1 protein]; Okadaic Acid results in increased degradation of and results in decreased expression of ESR1 mRNA
Okadaic Acid results in decreased expression of ESR1 protein
CTD PMID:15965230 PMID:19800873 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO Okadaic Acid results in increased expression of FAS mRNA
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of FAS mRNA
CTD PMID:31926150 PMID:33069748 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA CTD PMID:19840844 NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Okadaic Acid results in decreased expression of FDFT1 mRNA CTD PMID:28939011 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Okadaic Acid results in decreased expression of FDPS mRNA CTD PMID:28939011 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 decreases phosphorylation ISO Okadaic Acid results in decreased phosphorylation of FGFR4 protein CTD PMID:8576110 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Okadaic Acid results in increased expression of FIS1 protein CTD PMID:26732598 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Focad focadhesin decreases expression ISO Okadaic Acid results in decreased expression of FOCAD mRNA CTD PMID:25270620 NCBI chr 5:102,564,560...102,886,587
Ensembl chr 5:102,564,598...102,886,582
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP
ISO
Okadaic Acid promotes the reaction [Hydrogen Peroxide results in increased expression of FOS protein]
Okadaic Acid results in increased expression of FOS mRNA
CTD PMID:7963561 PMID:15136564 PMID:28939011 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Okadaic Acid results in increased expression of FOSL1 mRNA CTD PMID:19000923 PMID:31115591 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]]; Okadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]]; Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]] CTD PMID:24954032 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of FSTL1 mRNA CTD PMID:19840844 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Okadaic Acid affects the expression of GAPDH mRNA CTD PMID:22788371 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gimap6 GTPase, IMAP family member 6 increases expression ISO Okadaic Acid results in increased expression of GIMAP6 mRNA CTD PMID:25270620 NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
ISO Okadaic Acid results in increased expression of GJA1 mRNA
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GJA1 mRNA
CTD PMID:8597533 PMID:19840844 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO Okadaic Acid results in increased expression of GJB2 mRNA CTD PMID:8597533 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression ISO Okadaic Acid results in decreased expression of GJB5 mRNA CTD PMID:8597533 NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
JBrowse link
G Glo1 glyoxalase 1 decreases expression
multiple interactions
ISO Okadaic Acid results in decreased expression of GLO1 protein
[Okadaic Acid co-treated with gambierol] results in decreased expression of GLO1 protein
CTD PMID:19397276 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpc4 glypican 4 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GPC4 mRNA CTD PMID:19840844 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284
JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO Okadaic Acid results in increased expression of GPI mRNA CTD PMID:28939011 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO Okadaic Acid results in decreased expression of GPX1 mRNA CTD PMID:35577138 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
affects phosphorylation
increases expression
ISO [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Okadaic Acid; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]; Okadaic Acid inhibits the reaction [resveratrol results in decreased phosphorylation of GSK3B protein]
Okadaic Acid results in increased phosphorylation of GSK3B protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]; Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]
Okadaic Acid results in increased expression of GSK3B protein; Okadaic Acid results in increased expression of GSK3B protein modified form
CTD PMID:21715663 PMID:23292070 PMID:26836014 PMID:27050422 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression ISO Okadaic Acid results in decreased expression of GSTA1 mRNA CTD PMID:28939011 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Okadaic Acid results in increased expression of GSTM1 mRNA CTD PMID:28939011 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GSTM2 mRNA CTD PMID:19840844 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO Okadaic Acid results in increased expression of GSTM3 mRNA CTD PMID:28939011 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTO1 mRNA CTD PMID:19840844 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTP1 mRNA
Okadaic Acid results in increased expression of GSTP1 mRNA
CTD PMID:19840844 PMID:28939011 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO Okadaic Acid results in decreased expression of H1-4 mRNA CTD PMID:28939011 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO Okadaic Acid results in decreased expression of HAAO mRNA CTD PMID:25270620 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Okadaic Acid results in increased expression of HIF1A mRNA CTD PMID:28939011 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 decreases expression ISO Okadaic Acid results in decreased expression of H2AC6 mRNA CTD PMID:28939011 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hist1h2bc histone cluster 1, H2bc decreases expression ISO Okadaic Acid results in decreased expression of H2BC4 mRNA CTD PMID:25270620 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
JBrowse link
G Hk2 hexokinase 2 increases expression ISO Okadaic Acid results in increased expression of HK2 mRNA CTD PMID:28939011 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Okadaic Acid results in decreased expression of HMGCR mRNA CTD PMID:28939011 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression
multiple interactions
ISO Okadaic Acid results in increased expression of HPRT1 mRNA
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of HPRT1 mRNA
CTD PMID:19840844 PMID:25270620 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO Okadaic Acid results in increased expression of HSPA2 mRNA CTD PMID:28939011 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Okadaic Acid results in increased expression of HSPA5 protein CTD PMID:26732598 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
decreases expression
increases expression
affects expression
ISO [Okadaic Acid co-treated with gambierol] affects the expression of HSPB1 protein modified form; [Okadaic Acid co-treated with gambierol] results in increased expression of HSPB1 protein
Okadaic Acid results in decreased expression of HSPB1 protein
Okadaic Acid results in increased expression of HSPB1 protein
Okadaic Acid affects the expression of HSPB1 protein modified form
CTD PMID:19397276 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Htra2 HtrA serine peptidase 2 affects expression ISO Okadaic Acid affects the expression of HTRA2 mRNA CTD PMID:28939011 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IER3 mRNA CTD PMID:19840844 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Okadaic Acid] CTD PMID:10365914 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
increases expression
ISO
EXP
Okadaic Acid inhibits the reaction [IL1B protein results in decreased phosphorylation of RELA protein]
Okadaic Acid results in increased secretion of IL1B protein
Okadaic Acid results in increased expression of IL1B mRNA
[IL1B protein co-treated with Okadaic Acid] results in decreased expression of ELN mRNA
Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased expression of IL1B protein]
CTD PMID:8997264 PMID:11591705 PMID:23430110 PMID:35577138 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Okadaic Acid results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in decreased expression of and results in decreased secretion of IL4 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid] results in decreased expression of and results in decreased secretion of IL4 protein CTD PMID:33069748 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of and results in increased secretion of IL6 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid] results in increased expression of and results in increased secretion of IL6 protein
Okadaic Acid results in increased expression of IL6 mRNA
Okadaic Acid results in increased secretion of IL6 protein
CTD PMID:33069748 PMID:35577138 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il9 interleukin 9 increases expression ISO Okadaic Acid results in increased expression of IL9 mRNA CTD PMID:25270620 NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
JBrowse link
G Iqcd IQ motif containing D increases expression ISO Okadaic Acid results in increased expression of IQCD mRNA CTD PMID:28939011 NCBI chr12:35,955,522...35,972,420 JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IRAK1 mRNA CTD PMID:19840844 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Ireb2 iron responsive element binding protein 2 multiple interactions EXP Okadaic Acid inhibits the reaction [EGF protein results in decreased activity of IREB2 protein]; Okadaic Acid inhibits the reaction [TRH protein results in decreased activity of IREB2 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] CTD PMID:10889193 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO JAK2 protein affects the reaction [[PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in decreased susceptibility to Okadaic Acid] CTD PMID:21715663 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 affects expression ISO Okadaic Acid affects the expression of JPT1 mRNA CTD PMID:23561263 NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Okadaic Acid inhibits the reaction [Tretinoin results in decreased phosphorylation of JUN protein]
Okadaic Acid results in increased expression of JUN mRNA
CTD PMID:16052510 PMID:19000923 PMID:28939011 PMID:31115591 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Okadaic Acid results in increased expression of JUNB mRNA CTD PMID:19000923 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kyat3 kynurenine aminotransferase 3 decreases expression ISO Okadaic Acid results in decreased expression of KYAT3 mRNA CTD PMID:25270620 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Okadaic Acid results in increased expression of LAMC2 mRNA CTD PMID:25270620 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Okadaic Acid results in increased expression of LDLR mRNA CTD PMID:28939011 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 increases expression ISO Okadaic Acid results in increased expression of LGR5 mRNA CTD PMID:31115591 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
JBrowse link
G Lox lysyl oxidase multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LOX mRNA CTD PMID:19840844 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LPL mRNA CTD PMID:19840844 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrrn1 leucine rich repeat neuronal 1 increases expression ISO Okadaic Acid results in increased expression of LRRN1 mRNA CTD PMID:25270620 NCBI chr 4:140,476,752...140,520,210
Ensembl chr 4:140,476,324...140,518,620
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO Okadaic Acid results in increased expression of MANF mRNA CTD PMID:28939011 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression ISO Okadaic Acid results in increased expression of MAP1LC3A mRNA CTD PMID:25270620 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO Okadaic Acid results in increased expression of MAP2K3 mRNA CTD PMID:28939011 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 decreases expression ISO Okadaic Acid results in decreased expression of MAP3K10 mRNA CTD PMID:25270620 NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:82,955,207...82,974,084
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MAP3K12 mRNA CTD PMID:19840844 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of MAP3K5 mRNA CTD PMID:33069748 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
increases phosphorylation
multiple interactions
EXP
ISO
Okadaic Acid results in increased activity of MAPK1 protein
Okadaic Acid results in increased phosphorylation of MAPK1 protein
Quercetin inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPK1 protein]
Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]
CTD PMID:7723735 PMID:19716839 PMID:23335626 PMID:23775084 PMID:24395787 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
multiple interactions
increases phosphorylation
ISO
EXP
Okadaic Acid results in increased activity of MAPK3 protein
Quercetin inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPK3 protein]
Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]
CTD PMID:19716839 PMID:23335626 PMID:23775084 PMID:24395787 PMID:27050422 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions ISO Okadaic Acid results in increased phosphorylation of and results in increased activity of MAPK7 protein
Okadaic Acid results in increased phosphorylation of and results in increased activity of MAPK7 protein; U 0126 inhibits the reaction [Okadaic Acid results in increased phosphorylation of and results in increased activity of MAPK7 protein]
CTD PMID:19716839 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO Okadaic Acid results in increased expression of MAPK8 mRNA CTD PMID:28939011 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 affects expression ISO Okadaic Acid affects the expression of MAPRE2 mRNA CTD PMID:23561263 NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
affects phosphorylation
increases phosphorylation
ISO
EXP
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; morroniside inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]
Okadaic Acid affects the phosphorylation of MAPT protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]; Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein]; Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]
[Okadaic Acid co-treated with immunomycin] results in increased phosphorylation of MAPT protein; Okadaic Acid inhibits the reaction [Ionomycin results in decreased phosphorylation of MAPT protein]; Okadaic Acid inhibits the reaction [Potassium Chloride results in decreased phosphorylation of MAPT protein]
CTD PMID:7723735 PMID:9200503 PMID:21715663 PMID:21934130 PMID:26732598 More... NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MARCKS mRNA CTD PMID:19840844 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mars2 methionyl-tRNA synthetase 2, mitochondrial increases expression ISO Okadaic Acid results in increased expression of MARS2 mRNA CTD PMID:25270620 NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:56,720,983...56,723,820
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO [1,25-dihydroxyvitamin D co-treated with Okadaic Acid] promotes the reaction [VDR protein mutant form binds to MED1 protein] CTD PMID:16059639 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mesd mesoderm development LRP chaperone decreases expression ISO Okadaic Acid results in decreased expression of MESD protein CTD PMID:19397276 NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999
JBrowse link
G Mfn1 mitofusin 1 increases expression EXP Okadaic Acid results in increased expression of MFN1 protein CTD PMID:26732598 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 increases expression EXP Okadaic Acid results in increased expression of MFN2 protein CTD PMID:26732598 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 multiple interactions
increases expression
ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MGST3 mRNA
Okadaic Acid results in increased expression of MGST3 mRNA
CTD PMID:19840844 PMID:28939011 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor decreases expression ISO Okadaic Acid results in decreased expression of MLLT11 mRNA CTD PMID:23561263 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Okadaic Acid results in increased expression of MMP1 mRNA CTD PMID:28939011 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MMP2 mRNA CTD PMID:19840844 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mob3c MOB kinase activator 3C decreases expression ISO Okadaic Acid results in decreased expression of MOB3C mRNA CTD PMID:25270620 NCBI chr 5:129,306,255...129,315,264
Ensembl chr 5:129,306,569...129,315,256
JBrowse link
G Mphosph6 M phase phosphoprotein 6 increases expression ISO Okadaic Acid results in increased expression of MPHOSPH6 mRNA CTD PMID:25270620 NCBI chr19:45,860,152...45,870,117
Ensembl chr19:45,860,154...45,870,170
JBrowse link
G Mpp1 MAGUK p55 scaffold protein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MPP1 mRNA CTD PMID:19840844
G Mt-co2 mitochondrially encoded cytochrome c oxidase II affects expression ISO Okadaic Acid affects the expression of COX2 mRNA CTD PMID:22788371 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA CTD PMID:19840844 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Okadaic Acid results in decreased expression of MVD mRNA CTD PMID:28939011 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Okadaic Acid results in increased expression of MYC mRNA CTD PMID:31115591 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions ISO [Okadaic Acid co-treated with gambierol] results in increased expression of MYH7 protein modified form CTD PMID:19397276 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Nans N-acetylneuraminate synthase decreases expression ISO Okadaic Acid results in decreased expression of NANS protein CTD PMID:19397276 NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases activity
multiple interactions
ISO Okadaic Acid results in decreased activity of NCOR1 protein
[Tretinoin co-treated with Okadaic Acid] results in decreased activity of NCOR1 protein
CTD PMID:17312396 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 affects localization EXP Okadaic Acid affects the localization of NCOR2 protein CTD PMID:15773917 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO Okadaic Acid results in increased expression of NFE2L2 protein CTD PMID:12446695 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO anethole inhibits the reaction [Okadaic Acid results in increased activity of [NFKB1 protein binds to RELA protein]]; evodiamine inhibits the reaction [Okadaic Acid results in increased activity of NFKB1 protein]; Fenretinide inhibits the reaction [Okadaic Acid results in increased activity of NFKB1 protein]; lonafarnib inhibits the reaction [Okadaic Acid results in increased activity of NFKB1 protein]; Okadaic Acid inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; pregna-4,17-diene-3,16-dione inhibits the reaction [Okadaic Acid results in increased activity of NFKB1 protein]; zerumbone inhibits the reaction [Okadaic Acid results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:9973483 PMID:10871845 PMID:15090542 PMID:15322087 PMID:15710601 More... NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 multiple interactions
decreases expression
ISO [Okadaic Acid co-treated with gambierol] results in decreased expression of NME1 protein
Okadaic Acid results in decreased expression of NME1 protein
CTD PMID:19397276 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nop2 NOP2 nucleolar protein decreases expression ISO Okadaic Acid results in decreased expression of NOP2 mRNA CTD PMID:25270620 NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Okadaic Acid results in increased activity of NR1I2 protein CTD PMID:22206814 PMID:26921727 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Okadaic Acid results in decreased expression of NR3C1 mRNA; Okadaic Acid results in decreased expression of NR3C1 protein CTD PMID:21533367 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nts neurotensin multiple interactions
decreases activity
ISO Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]
Okadaic Acid results in decreased activity of NTS protein
CTD PMID:18313772 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Nup54 nucleoporin 54 increases expression ISO Okadaic Acid results in increased expression of NUP54 mRNA CTD PMID:19000923 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028
JBrowse link
G Ocln occludin increases expression ISO Okadaic Acid results in increased expression of OCLN mRNA CTD PMID:30926360 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression EXP Okadaic Acid results in increased expression of OPA1 protein CTD PMID:26732598 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Okadaic Acid results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Osbpl11 oxysterol binding protein-like 11 increases expression ISO Okadaic Acid results in increased expression of OSBPL11 mRNA CTD PMID:28939011 NCBI chr11:67,533,669...67,616,795
Ensembl chr11:67,533,672...67,596,444
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Okadaic Acid inhibits the reaction [Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] CTD PMID:16059913 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax4 paired box 4 decreases expression ISO Okadaic Acid results in decreased expression of PAX4 mRNA CTD PMID:25270620 NCBI chr 4:57,058,453...57,065,995
Ensembl chr 4:57,058,462...57,063,408
JBrowse link
G Pcbp1 poly(rC) binding protein 1 decreases expression
multiple interactions
ISO Okadaic Acid results in decreased expression of PCBP1 protein
[Okadaic Acid co-treated with gambierol] results in decreased expression of PCBP1 protein
CTD PMID:19397276 NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500
JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCBP2 mRNA CTD PMID:19840844 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Okadaic Acid results in decreased expression of PCMT1 protein CTD PMID:19397276 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCNA mRNA CTD PMID:19840844 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PDGFRA mRNA CTD PMID:19840844 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 increases expression ISO Okadaic Acid results in increased expression of PDHA1 mRNA CTD PMID:28939011 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PDIA3 mRNA CTD PMID:19840844 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO Okadaic Acid inhibits the reaction [Glucose affects the localization of PDX1 protein] CTD PMID:11574405 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pfdn2 prefoldin subunit 2 increases expression ISO Okadaic Acid results in increased expression of PFDN2 mRNA CTD PMID:28939011 NCBI chr13:83,772,301...83,791,367
Ensembl chr13:83,753,877...83,790,504
JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression ISO Okadaic Acid results in increased expression of PFDN5 mRNA CTD PMID:28939011 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [Okadaic Acid co-treated with gambierol] results in decreased expression of PGAM1 protein CTD PMID:19397276 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgr progesterone receptor decreases expression ISO Okadaic Acid results in decreased expression of PGR mRNA; Okadaic Acid results in decreased expression of PGR protein CTD PMID:15965230 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 increases expression ISO Okadaic Acid results in increased expression of PIAS2 mRNA CTD PMID:25270620 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO Okadaic Acid results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha increases expression ISO Okadaic Acid results in increased expression of PILRA mRNA CTD PMID:25270620 NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094
JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression ISO Okadaic Acid results in increased expression of PLA2G4A mRNA CTD PMID:25270620 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO Okadaic Acid results in increased expression of PLAUR mRNA CTD PMID:31115591 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Podxl podocalyxin-like multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PODXL mRNA CTD PMID:19840844 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
JBrowse link
G Polr2a RNA polymerase II subunit A increases phosphorylation ISO Okadaic Acid results in increased phosphorylation of POLR2A protein CTD PMID:8126066 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases phosphorylation
ISO
EXP
Okadaic Acid inhibits the reaction [Nafenopin results in increased activity of PPARA protein]; Okadaic Acid results in increased activity of and results in increased stability of PPARA protein
Okadaic Acid results in increased phosphorylation of PPARA protein
Okadaic Acid inhibits the reaction [Dehydroepiandrosterone results in decreased phosphorylation of PPARA protein]; Okadaic Acid inhibits the reaction [Dehydroepiandrosterone results in increased activity of PPARA protein]; Okadaic Acid inhibits the reaction [Nafenopin results in decreased phosphorylation of PPARA protein]; Okadaic Acid inhibits the reaction [Nafenopin results in increased activity of PPARA protein mutant form]; Okadaic Acid inhibits the reaction [Nafenopin results in increased activity of PPARA protein]; Okadaic Acid inhibits the reaction [pirinixic acid results in decreased phosphorylation of PPARA protein]
CTD PMID:15178457 PMID:18079279 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Okadaic Acid results in increased expression of PPARD mRNA CTD PMID:31115591 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Ppia peptidylprolyl isomerase A decreases expression
increases expression
ISO Okadaic Acid results in decreased expression of PPIA protein
Okadaic Acid results in increased expression of PPIA mRNA
CTD PMID:19397276 PMID:28939011 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppme1 protein phosphatase methylesterase 1 multiple interactions
increases expression
ISO morroniside inhibits the reaction [Okadaic Acid results in increased expression of PPME1 protein] CTD PMID:26836014 NCBI chr 1:154,668,099...154,715,079
Ensembl chr 1:154,668,109...154,715,110
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions
decreases activity
ISO
EXP
Okadaic Acid inhibits the reaction [Amiloride results in decreased phosphorylation of PPP1CA protein]
Okadaic Acid results in decreased activity of PPP1CA protein
CTD PMID:15767308 PMID:16059913 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions
decreases response to substance
decreases activity
ISO
EXP
[Okadaic Acid results in decreased activity of PPP2CA protein] which results in decreased susceptibility to Dexamethasone; morroniside inhibits the reaction [Okadaic Acid results in decreased methylation of and results in increased phosphorylation of and results in decreased activity of [PPP2CA protein binds to PPP2CB protein]]; Okadaic Acid inhibits the reaction [Arsenic Trioxide promotes the reaction [AKT1 protein binds to PPP2CA protein]]; Okadaic Acid results in decreased activity of [PPP2CA protein binds to PPP2CB protein]; Okadaic Acid results in decreased methylation of and results in increased phosphorylation of and results in decreased activity of [PPP2CA protein binds to PPP2CB protein]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride co-treated with Memantine] results in increased expression of PPP2CA mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride co-treated with Memantine] results in increased expression of PPP2CA protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in decreased expression of PPP2CA protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of PPP2CA mRNA
PPP2CA protein mutant form results in decreased susceptibility to Okadaic Acid
CTD PMID:15965230 PMID:21655183 PMID:22205926 PMID:26836014 PMID:29241734 More... NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta multiple interactions ISO morroniside inhibits the reaction [Okadaic Acid results in decreased methylation of and results in increased phosphorylation of and results in decreased activity of [PPP2CA protein binds to PPP2CB protein]]; Okadaic Acid results in decreased activity of [PPP2CA protein binds to PPP2CB protein]; Okadaic Acid results in decreased methylation of and results in increased phosphorylation of and results in decreased activity of [PPP2CA protein binds to PPP2CB protein] CTD PMID:26836014 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression ISO Okadaic Acid results in increased expression of PPP2R1A protein CTD PMID:18937299 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit increases expression ISO Okadaic Acid results in increased expression of PPP4C mRNA CTD PMID:25270620 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659
JBrowse link
G Prcp prolylcarboxypeptidase increases expression ISO Okadaic Acid results in increased expression of PRCP mRNA CTD PMID:25270620 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530
JBrowse link
G Prdx4 peroxiredoxin 4 increases expression ISO Okadaic Acid results in increased expression of PRDX4 mRNA CTD PMID:25270620 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions
decreases expression
ISO [Okadaic Acid co-treated with gambierol] results in decreased expression of PRDX5 protein
Okadaic Acid results in decreased expression of PRDX5 protein
CTD PMID:19397276 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions ISO [Okadaic Acid co-treated with gambierol] results in decreased expression of PRDX6 protein CTD PMID:19397276 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions ISO [calyculin A co-treated with Okadaic Acid] inhibits the reaction [2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [[8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein] results in increased activity of ARHGEF17 protein]] CTD PMID:23195829 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Ptger1 prostaglandin E receptor 1 decreases expression ISO Okadaic Acid results in decreased expression of PTGER1 mRNA CTD PMID:25270620 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Okadaic Acid results in increased expression of PTGS2 mRNA; Okadaic Acid results in increased expression of PTGS2 protein CTD PMID:8989914 PMID:9013627 PMID:31115591 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Okadaic Acid inhibits the reaction [cordycepin results in decreased phosphorylation of PTK2 protein] CTD PMID:28068557 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptn pleiotrophin multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PTN mRNA CTD PMID:19840844 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin multiple interactions
affects expression
ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PTTG1 mRNA
Okadaic Acid affects the expression of PTTG1 mRNA
CTD PMID:19840844 PMID:23561263 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 affects expression ISO Okadaic Acid affects the expression of QARS1 mRNA CTD PMID:22788371 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RACGAP1 mRNA CTD PMID:19840844 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad21 RAD21 cohesin complex component multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RAD21 mRNA CTD PMID:19840844 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] CTD PMID:14623285 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP Okadaic Acid promotes the reaction [alitretinoin results in increased activity of RARA protein] CTD PMID:15773917 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RB1 protein] CTD PMID:12621062 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL1 protein] CTD PMID:12621062 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein] CTD PMID:12621062 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Rbx1 ring-box 1 increases expression ISO Okadaic Acid results in increased expression of RBX1 mRNA CTD PMID:28939011 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
ISO anethole inhibits the reaction [Okadaic Acid results in increased activity of [NFKB1 protein binds to RELA protein]]; evodiamine inhibits the reaction [Okadaic Acid results in increased activity of RELA protein]; Fenretinide inhibits the reaction [Okadaic Acid results in increased activity of RELA protein]; lonafarnib inhibits the reaction [Okadaic Acid results in increased activity of RELA protein]; Okadaic Acid inhibits the reaction [IL1B protein results in decreased phosphorylation of RELA protein]; Okadaic Acid inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Okadaic Acid results in increased expression of and affects the localization of RELA protein; pregna-4,17-diene-3,16-dione inhibits the reaction [Okadaic Acid results in increased activity of RELA protein]; zerumbone inhibits the reaction [Okadaic Acid results in increased activity of [NFKB1 protein binds to RELA protein]]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid] results in increased expression of RELA protein; Quercetin inhibits the reaction [Okadaic Acid results in increased phosphorylation of RELA protein]
CTD PMID:9973483 PMID:10871845 PMID:11591705 PMID:15090542 PMID:15322087 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rgs5 regulator of G-protein signaling 5 affects expression ISO Okadaic Acid affects the expression of RGS5 mRNA CTD PMID:22788371 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
JBrowse link
G Rgs9 regulator of G-protein signaling 9 decreases expression ISO Okadaic Acid results in decreased expression of RGS9 mRNA CTD PMID:25270620 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
JBrowse link
G Rho rhodopsin decreases expression ISO Okadaic Acid results in decreased expression of RHO mRNA CTD PMID:25270620 NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773
JBrowse link
G Rnf135 ring finger protein 135 decreases expression ISO Okadaic Acid results in decreased expression of RNF135 mRNA CTD PMID:25270620 NCBI chr10:65,170,560...65,189,791
Ensembl chr10:65,170,560...65,262,804
JBrowse link
G Rpl7 ribosomal protein L7 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPL7 mRNA CTD PMID:19840844 NCBI chr 5:3,217,184...3,220,192 JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO Okadaic Acid results in decreased expression of RPS12 protein CTD PMID:19397276 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014
JBrowse link
G Rps20 ribosomal protein S20 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPS20 mRNA CTD PMID:19840844 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
increases phosphorylation
EXP naringin inhibits the reaction [Okadaic Acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rptn repetin increases expression ISO Okadaic Acid results in increased expression of RPTN mRNA CTD PMID:25270620 NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA protein CTD PMID:15225641 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sc5d sterol-C5-desaturase decreases expression ISO Okadaic Acid results in decreased expression of SC5D mRNA CTD PMID:28939011 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO Okadaic Acid results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Sdcbp2 syndecan binding protein 2 increases expression ISO Okadaic Acid results in increased expression of SDCBP2 mRNA CTD PMID:25270620 NCBI chr 3:140,060,746...140,098,063
Ensembl chr 3:140,070,540...140,098,057
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator decreases expression ISO Okadaic Acid results in decreased expression of SEC63 mRNA CTD PMID:28939011 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link
G Selenop selenoprotein P multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of SELENOP mRNA CTD PMID:19840844 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Semg1 semenogelin 1 decreases expression ISO Okadaic Acid results in decreased expression of SEMG1 protein CTD PMID:19397276 NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 increases expression EXP Okadaic Acid results in increased expression of SIGMAR1 protein CTD PMID:26732598 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity
EXP Okadaic Acid inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Okadaic Acid results in decreased activity of SLC19A1 protein
CTD PMID:17482559 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Slc25a4 solute carrier family 25 member 4 affects expression ISO Okadaic Acid affects the expression of SLC25A4 mRNA CTD PMID:22788371 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Okadaic Acid results in increased expression of SLC2A1 mRNA CTD PMID:19000923 PMID:28939011 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO Okadaic Acid results in decreased expression of SLCO1A2 mRNA CTD PMID:31926150 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions
increases response to substance
ISO Dehydroepiandrosterone Sulfate inhibits the reaction [SLCO1B3 protein results in increased susceptibility to Okadaic Acid]; Okadaic Acid inhibits the reaction [SLCO1B3 protein results in increased uptake of cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased susceptibility to Okadaic Acid]; Taurocholic Acid inhibits the reaction [SLCO1B3 protein results in increased susceptibility to Okadaic Acid] CTD PMID:26134461 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression ISO Okadaic Acid results in decreased expression of SLCO2B1 mRNA CTD PMID:31926150 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO Okadaic Acid results in decreased expression of SOD1 mRNA; Okadaic Acid results in decreased expression of SOD1 protein CTD PMID:19397276 PMID:35577138 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
increases expression
ISO [Okadaic Acid co-treated with gambierol] results in increased expression of SOD2 protein
Okadaic Acid results in decreased expression of SOD2 mRNA
Okadaic Acid results in increased expression of SOD2 mRNA
CTD PMID:8037686 PMID:19397276 PMID:35577138 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SPP1 mRNA CTD PMID:19840844 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SQLE mRNA CTD PMID:19840844 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO morroniside inhibits the reaction [Okadaic Acid results in increased phosphorylation of and results in increased activity of SRC protein]; Okadaic Acid results in increased phosphorylation of and results in increased activity of SRC protein CTD PMID:26836014 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 decreases expression ISO Okadaic Acid results in decreased expression of SREBF2 mRNA CTD PMID:28939011 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Srek1ip1 SREK1-interacting protein 1 increases expression ISO Okadaic Acid results in increased expression of SREK1IP1 mRNA CTD PMID:25270620 NCBI chr 2:35,975,978...35,999,636
Ensembl chr 2:35,975,989...35,999,636
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains decreases expression ISO Okadaic Acid results in decreased expression of SSC5D mRNA CTD PMID:25270620 NCBI chr 1:68,891,942...68,910,462
Ensembl chr 1:68,891,949...68,909,743
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 decreases expression ISO Okadaic Acid results in decreased expression of STARD4 mRNA CTD PMID:28939011 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of STAT1 protein modified form; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid] results in increased expression of STAT1 protein modified form CTD PMID:33069748 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stmn1 stathmin 1 increases expression ISO Okadaic Acid results in increased expression of STMN1 mRNA CTD PMID:19000923 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stx19 syntaxin 19 decreases expression ISO Okadaic Acid results in decreased expression of STX19 mRNA CTD PMID:25270620 NCBI chr11:172,855...178,053
Ensembl chr11:171,395...179,191
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO Okadaic Acid results in decreased expression of SUCLG2 mRNA CTD PMID:25270620 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SUMO2 mRNA CTD PMID:19840844 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513
JBrowse link
G Syn1 synapsin I multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SYN1 mRNA CTD PMID:19840844 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Tax1bp1 Tax1 binding protein 1 decreases expression ISO Okadaic Acid results in decreased expression of TAX1BP1 mRNA CTD PMID:23561263 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100
JBrowse link
G Tceal9 transcription elongation factor A like 9 increases expression ISO Okadaic Acid results in increased expression of TCEAL9 mRNA CTD PMID:25270620 NCBI chr  X:99,245,645...99,247,720
Ensembl chr  X:99,228,458...99,247,763
JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO Okadaic Acid promotes the reaction [CTNNB1 protein binds to TCF4 protein] CTD PMID:31115591 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tcp1 t-complex 1 increases expression ISO Okadaic Acid results in increased expression of TCP1 mRNA CTD PMID:28939011 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tex9 testis expressed 9 increases expression ISO Okadaic Acid results in increased expression of TEX9 mRNA CTD PMID:25270620 NCBI chr 8:73,168,519...73,213,935
Ensembl chr 8:73,177,810...73,214,261
JBrowse link
G Tf transferrin decreases uptake ISO Okadaic Acid results in decreased uptake of TF protein CTD PMID:16563724 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 increases expression ISO Okadaic Acid results in increased expression of TFCP2L1 mRNA CTD PMID:25270620 NCBI chr13:29,733,813...29,793,870
Ensembl chr13:29,733,840...29,793,870
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 multiple interactions ISO Okadaic Acid inhibits the reaction [sodium arsenite results in decreased phosphorylation of and affects the localization of TFE3 protein] CTD PMID:29945972 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571
JBrowse link
G Tfeb transcription factor EB multiple interactions ISO Okadaic Acid inhibits the reaction [sodium arsenite results in decreased phosphorylation of TFEB protein] CTD PMID:29945972 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tfrc transferrin receptor increases expression ISO Okadaic Acid results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS1 mRNA CTD PMID:19840844 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thbs2 thrombospondin 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS2 mRNA CTD PMID:19840844 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TIMP2 mRNA CTD PMID:19840844 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tjp1 tight junction protein 1 increases expression
decreases expression
ISO Okadaic Acid results in increased expression of TJP1 mRNA
Okadaic Acid results in decreased expression of TJP1 protein
CTD PMID:30926360 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tjp2 tight junction protein 2 increases expression ISO Okadaic Acid results in increased expression of TJP2 mRNA CTD PMID:30926360 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
G Tlcd1 TLC domain containing 1 increases expression ISO Okadaic Acid results in increased expression of TLCD1 mRNA CTD PMID:25270620 NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 decreases expression ISO Okadaic Acid results in decreased expression of TMED10 mRNA CTD PMID:25270620 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
G Tmem45a transmembrane protein 45A increases expression ISO Okadaic Acid results in increased expression of TMEM45A mRNA CTD PMID:25270620 NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526
JBrowse link
G Tmsb4x thymosin beta 4, X-linked multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA CTD PMID:19840844 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
increases expression
ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride] results in increased expression of and results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid] results in increased expression of and results in increased secretion of TNF protein; caffeic acid phenethyl ester inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; Calcitriol inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; epigallocatechin gallate inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; Quercetin inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; Sulindac inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]; Tamoxifen inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]
Okadaic Acid results in increased secretion of TNF protein
Okadaic Acid results in increased expression of TNF mRNA
Okadaic Acid inhibits the reaction [hydroquinone results in increased expression of TNF mRNA]; Okadaic Acid inhibits the reaction [hydroquinone results in increased expression of TNF protein]
CTD PMID:10757128 PMID:12628509 PMID:23288922 PMID:33069748 PMID:35577138 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO Okadaic Acid inhibits the reaction [Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] CTD PMID:16059913 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 affects expression ISO Okadaic Acid affects the expression of TOMM5 mRNA CTD PMID:22788371 NCBI chr 5:59,362,360...59,365,191
Ensembl chr 5:59,362,240...59,365,269
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TOP2A mRNA CTD PMID:19840844 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tor1a torsin family 1, member A increases expression ISO Okadaic Acid results in increased expression of TOR1A mRNA CTD PMID:28939011 NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691
JBrowse link
G Tp53 tumor protein p53 affects localization
affects response to substance
multiple interactions
decreases expression
ISO Okadaic Acid affects the localization of TP53 protein
TRP53 protein affects the susceptibility to Okadaic Acid
Okadaic Acid affects the reaction [Estradiol promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]; Okadaic Acid affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]; Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]; Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]; Okadaic Acid promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]
Okadaic Acid results in decreased expression of TP53 mRNA; Okadaic Acid results in decreased expression of TP53 protein
CTD PMID:18937299 PMID:20477944 PMID:21512803 PMID:24954032 PMID:31926150 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Okadaic Acid inhibits the reaction [TRH protein results in decreased activity of ACO1 protein]; Okadaic Acid inhibits the reaction [TRH protein results in decreased activity of IREB2 protein] CTD PMID:10889193 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trpc4ap transient receptor potential cation channel, subfamily C, member 4 associated protein increases expression ISO Okadaic Acid results in increased expression of TRPC4AP mRNA CTD PMID:25270620 NCBI chr 3:144,122,003...144,192,986
Ensembl chr 3:144,122,003...144,192,986
JBrowse link
G Tspan13 tetraspanin 13 increases expression ISO Okadaic Acid results in increased expression of TSPAN13 mRNA CTD PMID:25270620 NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TTC3 mRNA CTD PMID:19840844 NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
JBrowse link
G Txn1 thioredoxin 1 decreases expression
multiple interactions
ISO Okadaic Acid results in decreased expression of TXN protein
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TXN1 mRNA
CTD PMID:19397276 PMID:19840844 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of UBC mRNA CTD PMID:19840844 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 increases expression ISO Okadaic Acid results in increased expression of UBE2D1 mRNA CTD PMID:28939011 NCBI chr20:17,309,315...17,343,770
Ensembl chr20:17,309,315...17,342,295
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression ISO Okadaic Acid results in increased expression of UBE2D3 mRNA CTD PMID:28939011 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
JBrowse link
G Ube4b ubiquitination factor E4B decreases expression ISO Okadaic Acid results in decreased expression of UBE4B mRNA CTD PMID:25270620 NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of UCP2 mRNA CTD PMID:19840844 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 increases expression ISO Okadaic Acid results in increased expression of UGGT1 mRNA CTD PMID:28939011 NCBI chr 9:38,355,229...38,468,473
Ensembl chr 9:38,359,089...38,468,467
JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 decreases expression ISO Okadaic Acid results in decreased expression of UQCC2 mRNA CTD PMID:23561263 NCBI chr20:5,202,837...5,214,541
Ensembl chr20:5,202,837...5,214,164
JBrowse link
G Vcp valosin-containing protein decreases expression ISO Okadaic Acid results in decreased expression of VCP mRNA CTD PMID:28939011 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [1,25-dihydroxyvitamin D co-treated with Okadaic Acid] promotes the reaction [VDR protein mutant form binds to MED1 protein]; [1,25-dihydroxyvitamin D co-treated with Okadaic Acid] results in increased activity of VDR protein mutant form CTD PMID:16059639 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Okadaic Acid results in increased expression of VEGFA mRNA CTD PMID:19000923 PMID:28939011 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xbp1 X-box binding protein 1 increases expression EXP Okadaic Acid results in increased expression of XBP1 protein CTD PMID:26732598 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 increases expression ISO Okadaic Acid results in increased expression of XRCC4 mRNA CTD PMID:25270620 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
G Zdhhc15 zinc finger DHHC-type palmitoyltransferase 15 increases expression ISO Okadaic Acid results in increased expression of ZDHHC15 mRNA CTD PMID:25270620 NCBI chr  X:69,568,086...69,701,756
Ensembl chr  X:69,574,124...69,701,756
JBrowse link
G Zdhhc8 zinc finger DHHC-type palmitoyltransferase 8 decreases expression ISO Okadaic Acid results in decreased expression of ZDHHC8 mRNA CTD PMID:25270620 NCBI chr11:82,755,110...82,769,280
Ensembl chr11:82,755,143...82,767,734
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 increases expression ISO Okadaic Acid results in increased expression of ZEB2 mRNA CTD PMID:19000923 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
G Zfp260 zinc finger protein 260 increases expression ISO Okadaic Acid results in increased expression of ZFP260 mRNA CTD PMID:25270620 NCBI chr 1:85,336,567...85,349,896
Ensembl chr 1:85,336,618...85,350,067
JBrowse link
G Zfp36 zinc finger protein 36 multiple interactions ISO Okadaic Acid inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein] CTD PMID:23288922 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
pyrithione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of AKT1 protein; AKT1 protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein] CTD PMID:17098228 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Cd14 CD14 molecule multiple interactions ISO [Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]; pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]] CTD PMID:20089671 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO pyrithione inhibits the reaction [Lipopolysaccharides results in increased expression of CD86] CTD PMID:17126599 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 multiple interactions ISO 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [[Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [[Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]]; [Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein] CTD PMID:22317921 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP [Zinc co-treated with pyrithione] results in increased cleavage of CTNNB1 protein CTD PMID:17098228 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP [Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein; AKT1 protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein]; GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [Zinc co-treated with pyrithione] promotes the reaction [HGF protein results in increased expression of PCNA mRNA] CTD PMID:22374166 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO pyrithione analog results in increased expression of HMOX1 mRNA CTD PMID:23085594 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]]; pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]] CTD PMID:20089671 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPK1 protein CTD PMID:20201035 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPK3 protein CTD PMID:20201035 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions EXP [Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein; GSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein] CTD PMID:17098228 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mt1 metallothionein 1 increases expression ISO pyrithione analog results in increased expression of MT1 mRNA CTD PMID:23085594 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Zinc co-treated with pyrithione] promotes the reaction [HGF protein results in increased expression of PCNA mRNA] CTD PMID:22374166 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO [Zinc co-treated with pyrithione] results in decreased activity of PTPN1 protein CTD PMID:22374166 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Slc39a7 solute carrier family 39 member 7 multiple interactions ISO 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [[Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [[Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]]; [Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein] CTD PMID:22317921 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537
JBrowse link
rhodotorulic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
Salinomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot13 acyl-CoA thioesterase 13 decreases expression ISO salinomycin results in decreased expression of ACOT13 mRNA CTD PMID:19682730 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851
JBrowse link
G Actg1 actin, gamma 1 decreases expression ISO salinomycin results in decreased expression of ACTG1 mRNA CTD PMID:19682730 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO salinomycin results in decreased expression of ADAM12 mRNA CTD PMID:19682730 NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
JBrowse link
G Aebp1 AE binding protein 1 decreases expression ISO salinomycin results in decreased expression of AEBP1 mRNA CTD PMID:19682730 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Agps alkylglycerone phosphate synthase decreases expression ISO salinomycin results in decreased expression of AGPS mRNA CTD PMID:19682730 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
JBrowse link
G Aida axin interactor, dorsalization associated decreases expression ISO salinomycin results in decreased expression of AIDA mRNA CTD PMID:19682730 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920
JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 decreases expression ISO salinomycin results in decreased expression of AIMP2 mRNA CTD PMID:19682730 NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO salinomycin results in decreased expression of ALDH1A1 mRNA; salinomycin results in decreased expression of ALDH1A1 protein CTD PMID:25499043 PMID:30273566 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase decreases expression ISO salinomycin results in decreased expression of ALG2 mRNA CTD PMID:19682730 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase decreases expression ISO salinomycin results in decreased expression of ALKBH1 mRNA CTD PMID:19682730 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Ammecr1 AMMECR nuclear protein 1 decreases expression ISO salinomycin results in decreased expression of AMMECR1 mRNA CTD PMID:19682730 NCBI chr  X:106,465,982...106,571,382
Ensembl chr  X:106,466,699...106,571,487
JBrowse link
G Ankrd13c ankyrin repeat domain 13C decreases expression ISO salinomycin results in decreased expression of ANKRD13C mRNA CTD PMID:19682730 NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433
JBrowse link
G Anxa5 annexin A5 decreases expression ISO salinomycin results in decreased expression of ANXA5 mRNA CTD PMID:19682730 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Ar androgen receptor decreases expression ISO salinomycin results in decreased expression of AR mRNA; salinomycin results in decreased expression of AR protein CTD PMID:22215106 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 decreases expression ISO salinomycin results in decreased expression of ARAP1 mRNA CTD PMID:19682730 NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184
JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression ISO salinomycin results in decreased expression of ARF3 mRNA CTD PMID:19682730 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 decreases expression ISO salinomycin results in decreased expression of ARPC5 mRNA CTD PMID:19682730 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO salinomycin results in increased expression of ATF3 mRNA CTD PMID:22215106 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression
ISO [salinomycin co-treated with Calcitriol] results in increased expression of ATF6 mRNA
salinomycin results in increased expression of ATF6 mRNA
CTD PMID:35914560 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase decreases expression ISO salinomycin results in decreased expression of ATIC mRNA CTD PMID:19682730 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atp13a3 ATPase 13A3 decreases expression ISO salinomycin results in decreased expression of ATP13A3 mRNA CTD PMID:19682730 NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression ISO salinomycin results in decreased expression of ATP1B3 mRNA CTD PMID:19682730 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO salinomycin results in decreased expression of ATXN3 mRNA CTD PMID:19682730 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Bag6 BAG cochaperone 6 decreases expression ISO salinomycin results in decreased expression of BAG6 mRNA CTD PMID:19682730 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO salinomycin results in increased expression of BAK1 mRNA CTD PMID:34806536 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO salinomycin results in decreased expression of BAX mRNA CTD PMID:34806536 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
ISO [salinomycin co-treated with Calcitriol] results in increased expression of BBC3 mRNA
salinomycin results in increased expression of BBC3 mRNA
CTD PMID:35914560 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO salinomycin results in decreased expression of BCL2 mRNA CTD PMID:34806536 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO salinomycin results in increased expression of BCL2L1 mRNA CTD PMID:34806536 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO salinomycin results in decreased expression of BIRC5 protein CTD PMID:30273566 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bltp3a bridge-like lipid transfer protein family member 3A decreases expression ISO salinomycin results in decreased expression of BLTP3A mRNA CTD PMID:19682730 NCBI chr20:5,910,261...5,954,641
Ensembl chr20:5,910,260...5,952,404
JBrowse link
G C17h7orf25 similar to human chromosome 7 open reading frame 25 decreases expression ISO salinomycin results in decreased expression of C7ORF25 mRNA CTD PMID:19682730 NCBI chr17:50,543,231...50,549,880
Ensembl chr17:50,542,858...50,549,976
JBrowse link
G Cald1 caldesmon 1 decreases expression ISO salinomycin results in decreased expression of CALD1 mRNA CTD PMID:19682730 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Casp3 caspase 3 increases cleavage ISO salinomycin results in increased cleavage of CASP3 protein CTD PMID:30273566 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases expression ISO salinomycin results in increased expression of CASP7 mRNA CTD PMID:35914560 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 decreases expression ISO salinomycin results in decreased expression of CASP8 mRNA CTD PMID:19682730 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases cleavage
increases expression
multiple interactions
ISO salinomycin results in increased cleavage of CASP9 protein
salinomycin results in increased expression of CASP9 mRNA
[salinomycin co-treated with Calcitriol] results in increased expression of CASP9 mRNA
CTD PMID:30273566 PMID:35914560 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccdc43 coiled-coil domain containing 43 decreases expression ISO salinomycin results in decreased expression of CCDC43 mRNA CTD PMID:19682730 NCBI chr10:87,650,554...87,662,788
Ensembl chr10:87,650,556...87,662,818
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO salinomycin results in decreased expression of CCL2 mRNA CTD PMID:19682730 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO salinomycin results in decreased expression of CCNA2 mRNA CTD PMID:34806536 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO salinomycin results in decreased expression of CCNB1 mRNA CTD PMID:34806536 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [salinomycin co-treated with Calcitriol] results in decreased expression of CCND1 mRNA CTD PMID:35914560 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO salinomycin results in decreased expression of CCND2 mRNA CTD PMID:19682730 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccny cyclin Y decreases expression ISO salinomycin results in decreased expression of CCNY mRNA CTD PMID:19682730 NCBI chr17:57,385,002...57,512,860
Ensembl chr17:57,384,176...57,522,378
JBrowse link
G Cd44 CD44 molecule decreases expression ISO salinomycin results in decreased expression of CD44 protein CTD PMID:30273566 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc123 cell division cycle 123 decreases expression ISO salinomycin results in decreased expression of CDC123 mRNA CTD PMID:19682730 NCBI chr17:72,459,270...72,503,316
Ensembl chr17:72,459,282...72,503,316
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein] CTD PMID:26896736 PMID:30273566 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30273566 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO salinomycin results in increased expression of CDKN1A mRNA
[salinomycin co-treated with Calcitriol] results in increased expression of CDKN1A mRNA
CTD PMID:34806536 PMID:35914560 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cep350 centrosomal protein 350 decreases expression ISO salinomycin results in decreased expression of CEP350 mRNA CTD PMID:19682730 NCBI chr13:68,023,327...68,164,478
Ensembl chr13:68,026,891...68,165,214
JBrowse link
G Clec11a C-type lectin domain containing 11A decreases expression ISO salinomycin results in decreased expression of CLEC11A mRNA CTD PMID:19682730 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633
JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO salinomycin results in decreased expression of CLIC1 mRNA CTD PMID:19682730 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Cltc clathrin heavy chain decreases expression ISO salinomycin results in decreased expression of CLTC mRNA CTD PMID:19682730 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cnih4 cornichon family member 4 decreases expression ISO salinomycin results in decreased expression of CNIH4 mRNA CTD PMID:19682730 NCBI chr13:92,910,315...92,926,428
Ensembl chr13:92,910,315...92,927,853
JBrowse link
G Cnot4 CCR4-NOT transcription complex, subunit 4 decreases expression ISO salinomycin results in decreased expression of CNOT4 mRNA CTD PMID:19682730 NCBI chr 4:63,712,770...63,814,355
Ensembl chr 4:63,712,770...63,814,360
JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO salinomycin results in decreased expression of COA7 mRNA CTD PMID:19682730 NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199
JBrowse link
G Copb2 COPI coat complex subunit beta 2 decreases expression ISO salinomycin results in decreased expression of COPB2 mRNA CTD PMID:19682730 NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression ISO salinomycin results in decreased expression of CSNK2A1 mRNA CTD PMID:19682730 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 decreases expression ISO salinomycin results in decreased expression of CSTF1 mRNA CTD PMID:19682730 NCBI chr 3:161,144,522...161,156,294
Ensembl chr 3:161,144,548...161,156,300
JBrowse link
G Ctbs chitobiase decreases expression ISO salinomycin results in decreased expression of CTBS mRNA CTD PMID:19682730 NCBI chr 2:235,340,520...235,355,091
Ensembl chr 2:235,340,547...235,355,091
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of CTNNB1 mRNA]
salinomycin results in decreased expression of CTNNB1 mRNA
CTD PMID:26896736 PMID:34806536 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO salinomycin results in increased expression of CYP1A1 mRNA CTD PMID:34806536 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO salinomycin results in increased expression of CYP1A2 mRNA CTD PMID:34806536 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO salinomycin results in increased expression of CYP1B1 mRNA CTD PMID:34806536 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO salinomycin results in decreased activity of CYP2D6 protein CTD PMID:26282489 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
decreases expression
increases metabolic processing
ISO salinomycin results in decreased activity of CYP3A4 protein
salinomycin results in decreased expression of CYP3A4 mRNA
CYP3A4 protein results in increased metabolism of salinomycin
CTD PMID:26282489 PMID:34806536 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO salinomycin results in increased expression of CYP3A5 mRNA CTD PMID:34806536 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dbr1 debranching RNA lariats 1 decreases expression ISO salinomycin results in decreased expression of DBR1 mRNA CTD PMID:19682730 NCBI chr 8:100,139,039...100,150,768
Ensembl chr 8:100,139,034...100,151,030
JBrowse link
G Dcaf7 DDB1 and CUL4 associated factor 7 decreases expression ISO salinomycin results in decreased expression of DCAF7 mRNA CTD PMID:19682730 NCBI chr10:90,974,095...90,996,275
Ensembl chr10:90,974,095...90,996,275
JBrowse link
G Dcbld1 discoidin, CUB and LCCL domain containing 1 decreases expression ISO salinomycin results in decreased expression of DCBLD1 mRNA CTD PMID:19682730 NCBI chr20:31,618,556...31,711,697
Ensembl chr20:31,618,542...31,711,692
JBrowse link
G Dcn decorin decreases expression ISO salinomycin results in decreased expression of DCN mRNA CTD PMID:19682730 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression ISO salinomycin results in decreased expression of DCUN1D4 mRNA CTD PMID:19682730 NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO salinomycin results in increased expression of DDIT3 mRNA
[salinomycin co-treated with Calcitriol] results in increased expression of DDIT3 mRNA; Calcitriol promotes the reaction [salinomycin results in increased expression of DDIT3 mRNA]
CTD PMID:22215106 PMID:35914560 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO salinomycin results in increased expression of DDIT4 mRNA CTD PMID:22215106 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Desi2 desumoylating isopeptidase 2 decreases expression ISO salinomycin results in decreased expression of DESI2 mRNA CTD PMID:19682730 NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression ISO salinomycin results in decreased expression of DNAJC13 mRNA CTD PMID:19682730 NCBI chr 8:104,767,785...104,877,317
Ensembl chr 8:104,767,788...104,877,317
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO salinomycin results in decreased expression of DNMT3A mRNA CTD PMID:19682730 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dpf2 double PHD fingers 2 decreases expression ISO salinomycin results in decreased expression of DPF2 mRNA CTD PMID:19682730 NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO salinomycin results in decreased expression of DPYSL3 mRNA CTD PMID:19682730 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 decreases expression ISO salinomycin results in decreased expression of DVL3 mRNA CTD PMID:19682730 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
ISO salinomycin results in increased expression of EIF2AK3 mRNA
[salinomycin co-treated with Calcitriol] results in increased expression of EIF2AK3 mRNA
CTD PMID:35914560 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 decreases expression ISO salinomycin results in decreased expression of EIF4E2 mRNA CTD PMID:19682730 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
G Elp4 elongator acetyltransferase complex subunit 4 decreases expression ISO salinomycin results in decreased expression of ELP4 mRNA CTD PMID:19682730 NCBI chr 3:92,162,271...92,385,251
Ensembl chr 3:92,162,280...92,385,243
JBrowse link
G Emp3 epithelial membrane protein 3 decreases expression ISO salinomycin results in decreased expression of EMP3 mRNA CTD PMID:19682730 NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
JBrowse link
G Eng endoglin decreases expression ISO salinomycin results in decreased expression of ENG protein CTD PMID:30273566 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Erg ETS transcription factor ERG decreases expression ISO salinomycin results in decreased expression of ERG mRNA CTD PMID:22215106 NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase decreases expression ISO salinomycin results in decreased expression of ETAA1 mRNA CTD PMID:19682730 NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104
JBrowse link
G Ext1 exostosin glycosyltransferase 1 decreases expression ISO salinomycin results in decreased expression of EXT1 mRNA CTD PMID:19682730 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO salinomycin results in decreased expression of FGFR1 mRNA CTD PMID:19682730 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fhip2a FHF complex subunit HOOK interacting protein 2A decreases expression ISO salinomycin results in decreased expression of FHIP2A mRNA CTD PMID:19682730 NCBI chr 1:256,417,533...256,444,109
Ensembl chr 1:256,417,788...256,441,617
JBrowse link
G Fsd1l fibronectin type III and SPRY domain containing 1-like decreases expression ISO salinomycin results in decreased expression of FSD1L mRNA CTD PMID:19682730 NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression ISO salinomycin results in decreased expression of FTL mRNA CTD PMID:19682730 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO salinomycin results in decreased expression of FYN mRNA CTD PMID:19682730 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO salinomycin results in decreased expression of FZD2 mRNA CTD PMID:19682730 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO salinomycin results in increased expression of GADD45A mRNA CTD PMID:34806536 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma multiple interactions ISO [salinomycin co-treated with Calcitriol] results in increased expression of GADD45G mRNA CTD PMID:35914560 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO salinomycin results in decreased expression of GAP43 mRNA CTD PMID:19682730 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO salinomycin results in decreased expression of GAPDH mRNA CTD PMID:19682730 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gas6 growth arrest specific 6 decreases expression ISO salinomycin results in decreased expression of GAS6 mRNA CTD PMID:19682730 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Ghr growth hormone receptor decreases expression ISO salinomycin results in decreased expression of GHR mRNA CTD PMID:19682730 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression ISO salinomycin results in decreased expression of GLI1 mRNA; salinomycin results in decreased expression of GLI1 protein CTD PMID:25499043 PMID:30273566 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO salinomycin results in decreased expression of GNPDA1 mRNA CTD PMID:19682730 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486
JBrowse link
G Gorab golgin, RAB6-interacting decreases expression ISO salinomycin results in decreased expression of GORAB mRNA CTD PMID:19682730 NCBI chr13:75,745,678...75,762,307
Ensembl chr13:75,745,680...75,762,298
JBrowse link
G Gpc4 glypican 4 decreases expression ISO salinomycin results in decreased expression of GPC4 mRNA CTD PMID:19682730 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284
JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO salinomycin results in decreased expression of GPNMB mRNA CTD PMID:19682730 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO salinomycin results in decreased expression of GPRC5A mRNA CTD PMID:19682730 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO Calcitriol promotes the reaction [salinomycin results in increased expression of GPX1 mRNA] CTD PMID:35914560 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO salinomycin results in decreased expression of GSK3B mRNA CTD PMID:19682730 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gtf3c3 general transcription factor IIIC subunit 3 decreases expression ISO salinomycin results in decreased expression of GTF3C3 mRNA CTD PMID:19682730 NCBI chr 9:55,882,252...55,943,037
Ensembl chr 9:55,883,721...55,942,967
JBrowse link
G H2ax H2A.X variant histone decreases expression
multiple interactions
ISO salinomycin results in decreased expression of H2AX mRNA
[salinomycin co-treated with Calcitriol] results in decreased expression of H2AX mRNA
CTD PMID:35914560 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [salinomycin results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO salinomycin results in decreased expression of HIF1A mRNA CTD PMID:19682730 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO salinomycin results in decreased expression of HS2ST1 mRNA CTD PMID:19682730 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO [Calcitriol co-treated with salinomycin] results in increased expression of HSPA5 mRNA; Calcitriol promotes the reaction [salinomycin results in increased expression of HSPA5 mRNA] CTD PMID:35914560 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase decreases expression ISO salinomycin results in decreased expression of ICMT mRNA CTD PMID:19682730 NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO salinomycin binds to and results in decreased activity of IDO1 protein; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 mRNA]; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 protein] CTD PMID:32822738 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 decreases expression ISO salinomycin results in decreased expression of IDO2 protein CTD PMID:32822738 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Ifng interferon gamma multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased chemical synthesis of Kynurenine]; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 mRNA]; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK1 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK2 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of RELA protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:32822738 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression ISO salinomycin results in decreased expression of IGF2R mRNA CTD PMID:19682730 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO salinomycin results in decreased expression of IGFBP4 mRNA CTD PMID:19682730 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression ISO salinomycin results in decreased expression of IGFBP7 mRNA CTD PMID:19682730 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
JBrowse link
G Ints2 integrator complex subunit 2 decreases expression ISO salinomycin results in decreased expression of INTS2 mRNA CTD PMID:19682730 NCBI chr10:71,031,647...71,079,138
Ensembl chr10:71,031,647...71,079,076
JBrowse link
G Ints8 integrator complex subunit 8 decreases expression ISO salinomycin results in decreased expression of INTS8 mRNA CTD PMID:19682730 NCBI chr 5:24,295,542...24,344,642
Ensembl chr 5:24,297,191...24,344,740
JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO salinomycin results in decreased expression of IRF9 mRNA CTD PMID:19682730 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK1 protein] CTD PMID:32822738 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK2 protein] CTD PMID:32822738 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 decreases expression ISO salinomycin results in decreased expression of KDELR2 mRNA CTD PMID:19682730 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 decreases expression ISO salinomycin results in decreased expression of KDELR3 mRNA CTD PMID:19682730 NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600
JBrowse link
G Klf6 KLF transcription factor 6 increases expression ISO salinomycin results in increased expression of KLF6 mRNA CTD PMID:22215106 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klhl20 kelch-like family member 20 decreases expression ISO salinomycin results in decreased expression of KLHL20 mRNA CTD PMID:19682730 NCBI chr13:73,363,451...73,408,293
Ensembl chr13:73,363,455...73,408,337
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO salinomycin results in decreased expression of KLK3 mRNA; salinomycin results in decreased expression of KLK3 protein CTD PMID:22215106 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator decreases expression ISO salinomycin results in decreased expression of LARP1 mRNA CTD PMID:19682730 NCBI chr10:42,191,378...42,246,361
Ensembl chr10:42,191,325...42,243,371
JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO salinomycin results in decreased expression of LDHA mRNA CTD PMID:19682730 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lmbr1 limb development membrane protein 1 decreases expression ISO salinomycin results in decreased expression of LMBR1 mRNA CTD PMID:19682730 NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368
JBrowse link
G Lpin2 lipin 2 decreases expression ISO salinomycin results in decreased expression of LPIN2 mRNA CTD PMID:19682730 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP mRNA]; [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP protein] CTD PMID:30796972 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO salinomycin results in decreased phosphorylation of MAPK1 protein CTD PMID:28395993 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression ISO salinomycin results in decreased expression of MAPK14 mRNA CTD PMID:19682730 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO salinomycin results in decreased phosphorylation of MAPK3 protein CTD PMID:28395993 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 decreases expression ISO salinomycin results in decreased expression of MARS1 mRNA CTD PMID:19682730 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO salinomycin results in decreased expression of MMP10 mRNA CTD PMID:19682730 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression ISO salinomycin results in decreased expression of MMP14 mRNA CTD PMID:19682730 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases secretion
ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of MMP2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]
salinomycin results in decreased secretion of MMP2 protein
CTD PMID:26896736 PMID:28395993 PMID:30273566 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases secretion ISO salinomycin results in decreased secretion of MMP9 protein CTD PMID:28395993 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO salinomycin results in decreased expression of MT2A mRNA CTD PMID:19682730 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtrex Mtr4 exosome RNA helicase decreases expression ISO salinomycin results in decreased expression of MTREX mRNA CTD PMID:19682730 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO salinomycin results in decreased expression of MYC mRNA
[salinomycin co-treated with Calcitriol] results in decreased expression of MYC mRNA
CTD PMID:22215106 PMID:35914560 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myo10 myosin X decreases expression ISO salinomycin results in decreased expression of MYO10 mRNA CTD PMID:19682730 NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030
JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO salinomycin results in decreased expression of NAT10 mRNA CTD PMID:19682730 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [salinomycin co-treated with Calcitriol] results in decreased expression of NFKB1 mRNA CTD PMID:35914560 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO salinomycin results in increased expression of NFKBIA protein CTD PMID:32822738 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nid1 nidogen 1 decreases expression ISO salinomycin results in decreased expression of NID1 mRNA CTD PMID:19682730 NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Nid2 nidogen 2 decreases expression ISO salinomycin results in decreased expression of NID2 mRNA CTD PMID:19682730 NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843
JBrowse link
G Nol8 nucleolar protein 8 decreases expression ISO salinomycin results in decreased expression of NOL8 mRNA CTD PMID:19682730 NCBI chr17:14,990,394...15,013,784
Ensembl chr17:14,990,417...15,013,848
JBrowse link
G Notch3 notch receptor 3 decreases expression ISO salinomycin results in decreased expression of NOTCH3 mRNA CTD PMID:19682730 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO salinomycin results in decreased expression of NSF mRNA CTD PMID:19682730 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nuak2 NUAK family kinase 2 decreases expression ISO salinomycin results in decreased expression of NUAK2 mRNA CTD PMID:19682730 NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 decreases expression ISO salinomycin results in decreased expression of NUCKS1 mRNA CTD PMID:19682730 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
JBrowse link
G Nudt5 nudix hydrolase 5 decreases expression ISO salinomycin results in decreased expression of NUDT5 mRNA CTD PMID:19682730 NCBI chr17:72,435,690...72,459,008
Ensembl chr17:72,435,697...72,459,001
JBrowse link
G Nup37 nucleoporin 37 decreases expression ISO salinomycin results in decreased expression of NUP37 mRNA CTD PMID:19682730 NCBI chr 7:22,556,544...22,609,622
Ensembl chr 7:22,573,764...22,609,616
JBrowse link
G Nup62 nucleoporin 62 decreases expression ISO salinomycin results in decreased expression of NUP62 mRNA CTD PMID:19682730 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases expression ISO salinomycin results in decreased expression of PAK2 mRNA CTD PMID:19682730 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO salinomycin results in increased cleavage of PARP1 protein CTD PMID:30273566 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO salinomycin results in decreased expression of PDE8A mRNA CTD PMID:19682730 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression ISO salinomycin results in decreased expression of PDGFRB mRNA CTD PMID:19682730 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO salinomycin results in decreased expression of PFKFB3 mRNA CTD PMID:19682730 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO salinomycin results in decreased expression of PGK1 mRNA CTD PMID:19682730 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel decreases expression ISO salinomycin results in decreased expression of PKD2 mRNA CTD PMID:19682730 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Plaa phospholipase A2, activating protein decreases expression ISO salinomycin results in decreased expression of PLAA mRNA CTD PMID:19682730 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 decreases expression ISO salinomycin results in decreased expression of PLOD2 mRNA CTD PMID:19682730 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Plp2 proteolipid protein 2 decreases expression ISO salinomycin results in decreased expression of PLP2 mRNA CTD PMID:19682730 NCBI chr  X:14,834,249...14,837,648
Ensembl chr  X:14,834,231...14,838,514
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing decreases expression ISO salinomycin results in decreased expression of PNKD mRNA CTD PMID:19682730 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
JBrowse link
G Prepl prolyl endopeptidase-like decreases expression ISO salinomycin results in decreased expression of PREPL mRNA CTD PMID:19682730 NCBI chr 6:9,580,367...9,609,957
Ensembl chr 6:9,580,217...9,607,772
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression ISO salinomycin results in decreased expression of PSMA5 mRNA CTD PMID:19682730 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psmb7 proteasome 20S subunit beta 7 decreases expression ISO salinomycin results in decreased expression of PSMB7 mRNA CTD PMID:19682730 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 decreases expression ISO salinomycin results in decreased expression of PSMD8 mRNA CTD PMID:19682730 NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases phosphorylation ISO salinomycin results in decreased phosphorylation of PTK2 protein CTD PMID:28395993 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptov1 PTOV1, extended AT-hook containing adaptor protein decreases expression ISO salinomycin results in decreased expression of PTOV1 mRNA CTD PMID:19682730 NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613
JBrowse link
G Qng1 Q-nucleotide N-glycosylase 1 decreases expression ISO salinomycin results in decreased expression of QNG1 mRNA CTD PMID:19682730 NCBI chr17:6,281,377...6,288,976
Ensembl chr17:6,281,400...6,288,975
JBrowse link
G Rab23 RAB23, member RAS oncogene family decreases expression ISO salinomycin results in decreased expression of RAB23 mRNA CTD PMID:19682730 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO salinomycin results in decreased expression of RACK1 mRNA CTD PMID:19682730 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO salinomycin results in decreased expression of RAD23B mRNA CTD PMID:19682730 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of RELA protein] CTD PMID:32822738 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rin2 Ras and Rab interactor 2 decreases expression ISO salinomycin results in decreased expression of RIN2 mRNA CTD PMID:19682730 NCBI chr 3:133,086,858...133,303,604
Ensembl chr 3:133,086,749...133,303,604
JBrowse link
G Rnf8 ring finger protein 8 decreases expression ISO salinomycin results in decreased expression of RNF8 mRNA CTD PMID:19682730 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Rybp RING1 and YY1 binding protein decreases expression ISO salinomycin results in decreased expression of RYBP mRNA CTD PMID:19682730 NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316
JBrowse link
G Sdf4 stromal cell derived factor 4 decreases expression ISO salinomycin results in decreased expression of SDF4 mRNA CTD PMID:19682730 NCBI chr 5:166,586,581...166,606,661
Ensembl chr 5:166,586,390...166,604,521
JBrowse link
G Setd5 SET domain containing 5 decreases expression ISO salinomycin results in decreased expression of SETD5 mRNA CTD PMID:19682730 NCBI chr 4:146,217,172...146,294,896
Ensembl chr 4:146,217,180...146,294,894
JBrowse link
G Slc38a9 solute carrier family 38, member 9 decreases expression ISO salinomycin results in decreased expression of SLC38A9 mRNA CTD PMID:19682730 NCBI chr 2:44,291,637...44,374,897
Ensembl chr 2:44,291,989...44,368,955
JBrowse link
G Smg8 SMG8 nonsense mediated mRNA decay factor decreases expression ISO salinomycin results in decreased expression of SMG8 mRNA CTD PMID:19682730 NCBI chr10:71,886,742...71,895,776
Ensembl chr10:71,886,744...71,895,760
JBrowse link
G Smo smoothened, frizzled class receptor decreases expression ISO salinomycin results in decreased expression of SMO mRNA; salinomycin results in decreased expression of SMO protein CTD PMID:25499043 PMID:30273566 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 mRNA]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein] CTD PMID:26896736 PMID:30273566 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 decreases expression ISO salinomycin results in decreased expression of SNRNP25 mRNA CTD PMID:19682730 NCBI chr10:15,420,482...15,423,806
Ensembl chr10:15,420,486...15,423,804
JBrowse link
G Snx6 sorting nexin 6 decreases expression ISO salinomycin results in decreased expression of SNX6 mRNA CTD PMID:19682730 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO salinomycin results in decreased expression of SOCS3 protein CTD PMID:32822738 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [salinomycin co-treated with Calcitriol] results in decreased expression of SOD1 mRNA CTD PMID:35914560 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Spats2l spermatogenesis associated, serine-rich 2-like decreases expression ISO salinomycin results in decreased expression of SPATS2L mRNA CTD PMID:19682730 NCBI chr 9:59,319,949...59,493,864
Ensembl chr 9:59,320,276...59,493,967
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO salinomycin results in decreased expression of SPP1 mRNA CTD PMID:19682730 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srp54a signal recognition particle 54A decreases expression ISO salinomycin results in decreased expression of SRP54 mRNA CTD PMID:19682730 NCBI chr 6:72,587,584...72,626,878
Ensembl chr 6:72,587,605...72,625,189
JBrowse link
G Ssr1 signal sequence receptor subunit 1 decreases expression ISO salinomycin results in decreased expression of SSR1 mRNA CTD PMID:19682730 NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO salinomycin results in decreased expression of STAM mRNA CTD PMID:19682730 NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein] CTD PMID:32822738 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:32822738 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stau1 staufen double-stranded RNA binding protein 1 decreases expression ISO salinomycin results in decreased expression of STAU1 mRNA CTD PMID:19682730 NCBI chr 3:155,680,000...155,725,969
Ensembl chr 3:155,680,000...155,725,909
JBrowse link
G Stk39 serine threonine kinase 39 decreases expression ISO salinomycin results in decreased expression of STK39 mRNA CTD PMID:19682730 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of CTNNB1 mRNA]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of MMP2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 mRNA]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:26896736 PMID:30273566 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thumpd3 THUMP domain containing 3 decreases expression ISO salinomycin results in decreased expression of THUMPD3 mRNA CTD PMID:19682730 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246
JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 decreases expression ISO salinomycin results in decreased expression of TICAM2 mRNA CTD PMID:19682730 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression ISO salinomycin results in decreased expression of TIMP3 mRNA CTD PMID:19682730 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tnc tenascin C decreases expression ISO salinomycin results in decreased expression of TNC mRNA CTD PMID:19682730 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO salinomycin results in decreased expression of TP53 mRNA CTD PMID:34806536 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO salinomycin results in decreased expression of TUBB3 mRNA CTD PMID:19682730 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO salinomycin results in decreased expression of TUBB mRNA CTD PMID:19682730 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tymp thymidine phosphorylase decreases response to substance
increases expression
multiple interactions
ISO TYMP protein results in decreased susceptibility to salinomycin
salinomycin results in increased expression of TYMP mRNA; salinomycin results in increased expression of TYMP protein
[salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP mRNA]; [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP protein]; [tanespimycin co-treated with salinomycin] results in decreased expression of TYMP mRNA; acetylleucyl-leucyl-norleucinal inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]]; Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]; salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]; SB 203580 inhibits the reaction [salinomycin results in increased expression of TYMP mRNA]; SB 203580 promotes the reaction [[tanespimycin co-treated with salinomycin] results in decreased expression of TYMP mRNA]; tanespimycin inhibits the reaction [Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]]; tanespimycin inhibits the reaction [salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]]; tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP mRNA]; tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]
CTD PMID:30796972 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Tyw5 tRNA-yW synthesizing protein 5 decreases expression ISO salinomycin results in decreased expression of TYW5 mRNA CTD PMID:19682730 NCBI chr 9:58,961,100...58,979,188
Ensembl chr 9:58,961,106...58,979,188
JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression ISO salinomycin results in decreased expression of UBE2F mRNA CTD PMID:19682730 NCBI chr 9:91,845,975...91,881,145
Ensembl chr 9:91,845,987...91,880,594
JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S decreases expression ISO salinomycin results in decreased expression of UBE2S mRNA CTD PMID:19682730 NCBI chr 1:69,028,853...69,032,914
Ensembl chr 1:69,028,750...69,032,914
JBrowse link
G Vim vimentin multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:26896736 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vopp1 VOPP1 WW domain binding protein decreases expression ISO salinomycin results in decreased expression of VOPP1 mRNA CTD PMID:19682730 NCBI chr 4:87,363,678...87,432,747
Ensembl chr 4:87,363,477...87,450,375
JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 decreases expression ISO salinomycin results in decreased expression of WIPF1 mRNA CTD PMID:19682730 NCBI chr 3:58,314,521...58,416,668
Ensembl chr 3:58,314,542...58,372,742
JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 decreases expression ISO salinomycin results in decreased expression of XPNPEP1 mRNA CTD PMID:19682730 NCBI chr 1:252,001,366...252,052,077
Ensembl chr 1:252,001,367...252,051,479
JBrowse link
G Xpr1 xenotropic and polytropic retrovirus receptor 1 decreases expression ISO salinomycin results in decreased expression of XPR1 mRNA CTD PMID:19682730 NCBI chr13:67,441,205...67,585,950
Ensembl chr13:67,446,380...67,585,946
JBrowse link
G Yae1 YAE1 maturation factor of ABCE1 decreases expression ISO salinomycin results in decreased expression of YAE1 mRNA CTD PMID:19682730 NCBI chr17:47,027,033...47,033,549
Ensembl chr17:47,027,019...47,033,546
JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression ISO salinomycin results in decreased expression of ZMAT3 mRNA CTD PMID:19682730 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator decreases expression ISO salinomycin results in decreased expression of ZYG11B mRNA CTD PMID:19682730 NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736
JBrowse link
valinomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Valinomycin results in decreased activity of ABCB11 protein CTD PMID:12739759 PMID:20829430 PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Casp3 caspase 3 increases cleavage
increases activity
ISO Valinomycin results in increased cleavage of CASP3 protein
Valinomycin results in increased activity of CASP3 protein
CTD PMID:18926839 PMID:28157593 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Valinomycin affects the localization of CYCS protein CTD PMID:19193189 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Valinomycin binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Valinomycin binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Nnat neuronatin decreases response to substance EXP NNAT protein results in decreased susceptibility to Valinomycin CTD PMID:12101027 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions EXP Valinomycin inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents] CTD PMID:15860731 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Valinomycin promotes the reaction [SLC18A2 protein results in increased uptake of Serotonin] CTD PMID:18287335 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Valinomycin binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    role 19820
      biological role 19818
        biophysical role 14057
          membrane transport modulator 13877
            ionophore 1288
              24-dehydrozincophorin 0
              CCCP 46
              alborixin 6
              beauvericin 199
              calcium ionophore + 618
              carbonyl cyanide p-trifluoromethoxyphenylhydrazone 71
              enniatin + 210
              griseochelin 0
              indanomycin 0
              iron ionophore + 270
              lasalocid 20
              lasalocid sodium 0
              monensin A 17
              mutalomycin 0
              mutalomycin sodium salt 0
              potassium ionophore + 312
              pyrithione 16
              tridodecylamine 0
paths to the root