Mab21l4 (mab-21 like 4) - Rat Genome Database

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Gene: Mab21l4 (mab-21 like 4) Rattus norvegicus
Analyze
Symbol: Mab21l4
Name: mab-21 like 4
RGD ID: 1563692
Description: Orthologous to human MAB21L4 (mab-21 like 4); INTERACTS WITH acetamide; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC501185; LOC501185; RGD1563692; similar to hypothetical protein FLJ22671; uncharacterized protein C2orf54 homolog; uncharacterized protein LOC501185
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,138,408 - 101,148,516 (-)NCBIGRCr8
mRatBN7.2993,690,455 - 93,701,267 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,690,999 - 93,700,506 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9102,126,555 - 102,136,062 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,262,484 - 107,271,990 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,618,634 - 105,628,140 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,296,780 - 100,307,415 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,296,781 - 100,306,829 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0999,954,885 - 99,965,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,427,931 - 92,437,438 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera991,226,354 - 91,235,861 (-)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Mab21l4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,138,408 - 101,148,516 (-)NCBIGRCr8
mRatBN7.2993,690,455 - 93,701,267 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,690,999 - 93,700,506 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9102,126,555 - 102,136,062 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,262,484 - 107,271,990 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,618,634 - 105,628,140 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,296,780 - 100,307,415 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,296,781 - 100,306,829 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0999,954,885 - 99,965,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,427,931 - 92,437,438 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera991,226,354 - 91,235,861 (-)NCBICelera
Cytogenetic Map9q36NCBI
MAB21L4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,886,048 - 240,896,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,886,048 - 240,896,889 (-)EnsemblGRCh38hg38GRCh38
GRCh372241,825,465 - 241,835,573 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,474,138 - 241,484,246 (-)NCBINCBI36Build 36hg18NCBI36
Celera2235,498,112 - 235,508,356 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2233,586,038 - 233,596,152 (-)NCBIHuRef
CHM1_12241,831,514 - 241,841,622 (-)NCBICHM1_1
T2T-CHM13v2.02241,385,221 - 241,396,155 (-)NCBIT2T-CHM13v2.0
Mab21l4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,079,076 - 93,088,679 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,079,071 - 93,088,670 (-)EnsemblGRCm39 Ensembl
GRCm38193,151,354 - 93,160,956 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,151,349 - 93,160,948 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,047,932 - 95,057,525 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,981,762 - 94,991,354 (-)NCBIMGSCv36mm8
Celera196,096,009 - 96,105,603 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.03NCBI
Mab21l4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542701,633 - 709,315 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955542699,717 - 708,760 (+)NCBIChiLan1.0ChiLan1.0
MAB21L4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,574,547 - 143,584,700 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,589,512 - 143,599,665 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,144,248 - 128,154,670 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B246,946,812 - 246,956,949 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,946,812 - 246,956,949 (-)Ensemblpanpan1.1panPan2
MAB21L4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12550,731,528 - 50,738,661 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,195,414 - 51,230,786 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,177,278 - 51,212,387 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,177,283 - 51,183,962 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,018,276 - 51,025,673 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02550,764,682 - 50,799,949 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,040,504 - 51,075,966 (-)NCBIUU_Cfam_GSD_1.0
Mab21l4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,366,644 - 192,374,541 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936745844,883 - 852,803 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936745845,240 - 852,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAB21L4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115139,734,539 - 139,745,131 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215157,631,214 - 157,649,070 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAB21L4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110126,952,353 - 126,964,319 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10126,949,416 - 126,962,277 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604072,426,311 - 72,435,657 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mab21l4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,078,945 - 5,087,436 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248475,079,755 - 5,087,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mab21l4
45 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:116
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000038563
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)992491589100929786Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat

Markers in Region
BQ195863  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2993,690,520 - 93,690,726 (+)MAPPERmRatBN7.2
Rnor_6.09100,296,844 - 100,297,049NCBIRnor6.0
Rnor_5.0999,954,949 - 99,955,154UniSTSRnor5.0
RGSC_v3.4992,427,453 - 92,427,658UniSTSRGSC3.4
Celera991,225,876 - 91,226,081UniSTS
RH 3.4 Map9797.1UniSTS
Cytogenetic Map9q36UniSTS
RH134296  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2993,691,032 - 93,691,218 (+)MAPPERmRatBN7.2
Rnor_6.09100,297,356 - 100,297,541NCBIRnor6.0
Rnor_5.0999,955,461 - 99,955,646UniSTSRnor5.0
RGSC_v3.4992,427,965 - 92,428,150UniSTSRGSC3.4
Celera991,226,388 - 91,226,573UniSTS
RH 3.4 Map9797.7UniSTS
Cytogenetic Map9q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 5 4 80 54 65 34 11 34 6 110 17 72 45 56 31

Sequence


Ensembl Acc Id: ENSRNOT00000038563   ⟹   ENSRNOP00000030463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl993,690,999 - 93,700,506 (-)Ensembl
Rnor_6.0 Ensembl9100,297,322 - 100,306,829 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087584   ⟹   ENSRNOP00000070129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl9100,296,781 - 100,306,194 (-)Ensembl
RefSeq Acc Id: NM_001109311   ⟹   NP_001102781
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,138,408 - 101,147,915 (-)NCBI
mRatBN7.2993,690,999 - 93,700,506 (-)NCBI
Rnor_6.09100,297,322 - 100,306,829 (-)NCBI
Rnor_5.0999,954,885 - 99,965,505 (-)NCBI
RGSC_v3.4992,427,931 - 92,437,438 (-)RGD
Celera991,226,354 - 91,235,861 (-)RGD
Sequence:
RefSeq Acc Id: XM_006245547   ⟹   XP_006245609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,138,630 - 101,148,513 (-)NCBI
mRatBN7.2993,690,457 - 93,701,116 (-)NCBI
Rnor_6.09100,296,780 - 100,307,415 (-)NCBI
Rnor_5.0999,954,885 - 99,965,505 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039084126   ⟹   XP_038940054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,140,165 - 101,148,516 (-)NCBI
mRatBN7.2993,692,757 - 93,701,267 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102781 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245609 (Get FASTA)   NCBI Sequence Viewer  
  XP_038940054 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI62036 (Get FASTA)   NCBI Sequence Viewer  
  EDL91959 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030463.3
RefSeq Acc Id: NP_001102781   ⟸   NM_001109311
- UniProtKB: B1WC80 (UniProtKB/TrEMBL),   F7FIX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245609   ⟸   XM_006245547
- Peptide Label: isoform X1
- UniProtKB: B1WC80 (UniProtKB/TrEMBL),   F7FIX6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070129   ⟸   ENSRNOT00000087584
Ensembl Acc Id: ENSRNOP00000030463   ⟸   ENSRNOT00000038563
RefSeq Acc Id: XP_038940054   ⟸   XM_039084126
- Peptide Label: isoform X2
Protein Domains
Mab-21-like HhH/H2TH-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WC80-F1-model_v2 AlphaFold B1WC80 1-452 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563692 AgrOrtholog
BioCyc Gene G2FUF-26656 BioCyc
Ensembl Genes ENSRNOG00000023557 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038563.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1410.40 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7097280 IMAGE-MGC_LOAD
InterPro Mab-21_dom UniProtKB/TrEMBL
  Mab-21_HhH/H2TH-like UniProtKB/TrEMBL
KEGG Report rno:501185 UniProtKB/TrEMBL
MGC_CLONE MGC:187952 IMAGE-MGC_LOAD
NCBI Gene 501185 ENTREZGENE
PANTHER CELL FATE DETERMINING PROTEIN MAB21-RELATED UniProtKB/TrEMBL
  PTHR10656:SF7 UniProtKB/TrEMBL
Pfam Mab-21_C UniProtKB/TrEMBL
PhenoGen Mab21l4 PhenoGen
RatGTEx ENSRNOG00000023557 RatGTEx
SMART Mab-21 UniProtKB/TrEMBL
UniProt B1WC80 ENTREZGENE, UniProtKB/TrEMBL
  F7FIX6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-20 Mab21l4  mab-21 like 4  RGD1563692  similar to hypothetical protein FLJ22671  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563692  similar to hypothetical protein FLJ22671   RGD1563692_predicted  similar to hypothetical protein FLJ22671 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563692_predicted  similar to hypothetical protein FLJ22671 (predicted)  LOC501185  similar to hypothetical protein FLJ22671  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501185  similar to hypothetical protein FLJ22671      Symbol and Name status set to provisional 70820 PROVISIONAL