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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:potassium ionophore
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Accession:CHEBI:88227 term browser browse the term
Definition:Any ionophore capable of transportation of potassium ions across membranes.
Synonyms:related_synonym: potassium ionophores
 xref: PMID:11841304


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bafilomycin A1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Aim2 absent in melanoma 2 multiple interactions ISO [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of AIM2 protein CTD PMID:32645460 NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] CTD PMID:22689575 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Alb albumin decreases uptake ISO bafilomycin A1 results in decreased uptake of ALB protein CTD PMID:16313995 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bafilomycin A1 results in increased expression of APAF1 protein CTD PMID:28483490 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] CTD PMID:16769263 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]] CTD PMID:29938581 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bafilomycin A1 inhibits the reaction [Hydroxychloroquine results in increased activity of BAX protein] CTD PMID:12813466 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bafilomycin A1 results in decreased expression of BCL2 mRNA CTD PMID:31310755 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO
EXP
bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein]
[Swainsonine co-treated with bafilomycin A1] results in increased expression of BECN1 protein; bafilomycin A1 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BECN1 protein]
bafilomycin A1 results in increased expression of BECN1 protein
CTD PMID:32645460 PMID:33186601 PMID:33242459 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:23111315 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
increases expression
EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]
vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein]
bafilomycin A1 results in increased expression of BID protein modified form
CTD PMID:26853465 PMID:28378122 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of BNIP3 mRNA; bafilomycin A1 results in increased expression of BNIP3 protein
BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; capivasertib affects the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; Lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; vistusertib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]
CTD PMID:25981168 PMID:26853465 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G C1qtnf9 C1q and TNF related 9 multiple interactions EXP bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] CTD PMID:32278738 NCBI chr15:41,069,579...41,080,961
Ensembl chr15:41,069,507...41,081,159
JBrowse link
G Casp3 caspase 3 decreases activity
increases cleavage
multiple interactions
increases activity
ISO
EXP
bafilomycin A1 results in decreased activity of CASP3 protein
bafilomycin A1 results in increased cleavage of CASP3 protein
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]
bafilomycin A1 results in increased activity of CASP3 protein
[Swainsonine co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]
[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; [bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein]
CTD PMID:20876807 PMID:23380477 PMID:24321340 PMID:24889822 PMID:25266202 PMID:25981168 PMID:26853465 PMID:28063998 PMID:28378122 PMID:29111403 PMID:30240709 PMID:32708634 PMID:33076330 PMID:33186601 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases activity ISO bafilomycin A1 results in increased activity of CASP4 protein CTD PMID:20371669 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 increases activity
decreases activity
ISO bafilomycin A1 results in increased activity of CASP7 protein
bafilomycin A1 results in decreased activity of CASP7 protein
CTD PMID:20371669 PMID:25981168 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]
CTD PMID:28378122 PMID:29111403 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP9 protein]
CTD PMID:28378122 PMID:30240709 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of CCND1 protein] CTD PMID:33359579 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO bafilomycin A1 inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] CTD PMID:29074359 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Ctsb cathepsin B multiple interactions ISO bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]; bafilomycin A1 inhibits the reaction [Hydroxychloroquine affects the localization of CTSB protein] CTD PMID:12813466 PMID:23380477 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO bafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:26682054 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
EXP bafilomycin A1 results in increased expression of DDIT4 protein
[EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein
CTD PMID:22689575 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Aspartic Acid; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Taurine; [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein; bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine] CTD PMID:22689575 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:22689575 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Epor erythropoietin receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Aristolochic Acids results in increased degradation of and results in decreased expression of EPOR protein] CTD PMID:26136230 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:20200208 PMID:28378122 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] CTD PMID:29371327 NCBI chr 4:66,276,835...66,284,868
Ensembl chr 4:66,276,835...66,284,868
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased acetylation of FOXO1 protein]] CTD PMID:24889822 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of HIF1A protein
HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]
CTD PMID:25981168 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of HMOX1 protein
[bafilomycin A1 co-treated with methanandamide] results in increased expression of HMOX1 protein; [bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; bafilomycin A1 inhibits the reaction [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of HMOX1 protein]
CTD PMID:29796178 PMID:33076330 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma decreases expression ISO bafilomycin A1 results in decreased expression of IFNG mRNA CTD PMID:16932910 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of IL1B mRNA
[bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]
CTD PMID:16932910 PMID:24158569 PMID:32645460 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression ISO bafilomycin A1 results in increased expression of IL6 mRNA CTD PMID:16932910 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]
CTD PMID:22689575 PMID:32283200 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 increases response to substance ISO LRRK2 gene mutant form results in increased susceptibility to bafilomycin A1 CTD PMID:25017139 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein]
bafilomycin A1 results in increased expression of MAP1LC3A protein modified form
CTD PMID:30871063 PMID:31120128 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
increases expression
increases cleavage
decreases degradation
ISO
EXP
[di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [metarrestin results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
bafilomycin A1 results in increased lipidation of MAP1LC3B protein
[Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form]
bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein]
bafilomycin A1 results in increased cleavage of MAP1LC3B protein
bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form
bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
CTD PMID:23880069 PMID:24145604 PMID:25301941 PMID:26459185 PMID:26853465 PMID:27305347 PMID:29248574 PMID:29524503 PMID:29908302 PMID:29938581 PMID:30209975 PMID:31310755 PMID:32278738 PMID:32525084 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK1 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein]
bafilomycin A1 results in increased expression of MAPK1 protein modified form
CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK3 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK3 protein]
bafilomycin A1 results in increased expression of MAPK3 protein modified form
CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO bafilomycin A1 results in decreased phosphorylation of MTOR protein CTD PMID:31310755 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] CTD PMID:24532803 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[Particulate Matter co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [[Silicon Dioxide co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Silicon Dioxide results in increased expression of NFE2L2 protein]
bafilomycin A1 results in increased expression of NFE2L2 protein
CTD PMID:30698894 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein]
bafilomycin A1 results in increased expression of NLRP3 protein
CTD PMID:32645460 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO bafilomycin A1 results in decreased expression of NR5A1 protein CTD PMID:29524503 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
ISO bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]
bafilomycin A1 results in increased expression of PARP1 protein modified form
CTD PMID:20876807 PMID:21616090 PMID:24321340 PMID:25981168 PMID:28063998 PMID:29111403 PMID:31310755 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of PCNA mRNA] CTD PMID:33359579 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO bafilomycin A1 affects the localization of and results in increased activity of RELA protein CTD PMID:10339586 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
ISO
EXP
bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein
bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:22689575 PMID:31310755 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]] CTD PMID:24889822 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents]; bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Zinc]; bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174
JBrowse link
G Slc30a3 solute carrier family 30 member 3 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 6:26,629,752...26,650,106
Ensembl chr 6:26,642,783...26,650,105
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein]
bafilomycin A1 results in increased expression of SNAI1 protein
CTD PMID:32645460 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snca synuclein alpha multiple interactions
increases expression
ISO [bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein
bafilomycin A1 results in increased expression of SNCA protein
CTD PMID:26031332 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sort1 sortilin 1 decreases expression ISO bafilomycin A1 results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
bafilomycin A1 results in increased expression of SQSTM1 protein
bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]
[Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [metarrestin results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
[bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
CTD PMID:21778691 PMID:21858812 PMID:23151917 PMID:24145604 PMID:24238063 PMID:24889822 PMID:25939952 PMID:25943029 PMID:26031332 PMID:27305347 PMID:28125038 PMID:29248574 PMID:29524503 PMID:30698894 PMID:32186374 PMID:32645460 PMID:33359579 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tlr8 toll-like receptor 8 multiple interactions ISO bafilomycin A1 inhibits the reaction [resiquimod results in increased activity of TLR8 protein] CTD PMID:21398612 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TNF mRNA
[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
CTD PMID:16932910 PMID:24145604 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TOMM20 protein
Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein]
CTD PMID:30209975 NCBI chr19:59,863,421...59,873,411
Ensembl chr19:59,863,421...59,873,411
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein] CTD PMID:23380477 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions EXP bafilomycin A1 affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide affects the reaction [Glucose affects the phosphorylation of ULK1 protein]] CTD PMID:29128638 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions
increases expression
ISO Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] CTD PMID:30209975 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein CTD PMID:30698894 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein]
bafilomycin A1 results in increased expression of VIM protein
CTD PMID:32645460 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
nigericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp9 aquaporin 9 multiple interactions ISO Nigericin inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Nigericin inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] CTD PMID:28798983 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Casp1 caspase 1 multiple interactions
increases cleavage
ISO [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; CASP1 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]
Nigericin results in increased cleavage of CASP1 protein
arsenic trioxide inhibits the reaction [Nigericin results in increased cleavage of CASP1 protein]; sodium arsenite inhibits the reaction [Nigericin results in increased cleavage of CASP1 protein]
CTD PMID:18403674 PMID:23430110 PMID:24337744 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions ISO Nigericin promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
increases cleavage
ISO [Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Nigericin] results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein; arsenic trioxide inhibits the reaction [Nigericin results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein]; Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased expression of IL1B protein]; sodium arsenite inhibits the reaction [Nigericin results in increased cleavage of IL1B protein]
Nigericin results in increased secretion of IL1B protein
[Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B protein; CASP1 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [Nigericin results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [Nigericin results in increased secretion of IL1B protein]
CTD PMID:18403674 PMID:19130485 PMID:23430110 PMID:24337744 PMID:29642561 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [Nigericin results in increased secretion of IL1B protein] CTD PMID:18403674 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nnat neuronatin decreases response to substance EXP NNAT protein results in decreased susceptibility to Nigericin CTD PMID:12101027 NCBI chr 3:154,043,873...154,046,334
Ensembl chr 3:154,043,873...154,046,330
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO PYCARD protein affects the reaction [Nigericin results in increased secretion of IL1B protein] CTD PMID:18403674 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Nigericin results in decreased expression of STAR protein CTD PMID:16469751 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Lipopolysaccharides co-treated with Nigericin] results in increased expression of TNF protein CTD PMID:23430110 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Salinomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot13 acyl-CoA thioesterase 13 decreases expression ISO salinomycin results in decreased expression of ACOT13 mRNA CTD PMID:19682730 NCBI chr17:42,241,141...42,253,611
Ensembl chr17:42,241,159...42,253,649
JBrowse link
G Actg1 actin, gamma 1 decreases expression ISO salinomycin results in decreased expression of ACTG1 mRNA CTD PMID:19682730 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO salinomycin results in decreased expression of ADAM12 mRNA CTD PMID:19682730 NCBI chr 1:205,951,840...206,286,294
Ensembl chr 1:205,956,342...206,282,575
JBrowse link
G Aebp1 AE binding protein 1 decreases expression ISO salinomycin results in decreased expression of AEBP1 mRNA CTD PMID:19682730 NCBI chr14:86,101,253...86,111,323
Ensembl chr14:86,101,277...86,111,306
JBrowse link
G Agps alkylglycerone phosphate synthase decreases expression ISO salinomycin results in decreased expression of AGPS mRNA CTD PMID:19682730 NCBI chr 3:62,648,352...62,749,250
Ensembl chr 3:62,648,447...62,749,153
JBrowse link
G Aida axin interactor, dorsalization associated decreases expression ISO salinomycin results in decreased expression of AIDA mRNA CTD PMID:19682730 NCBI chr13:101,698,096...101,724,928
Ensembl chr13:101,698,096...101,724,923
JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 decreases expression ISO salinomycin results in decreased expression of AIMP2 mRNA CTD PMID:19682730 NCBI chr12:12,738,784...12,748,345
Ensembl chr12:12,738,812...12,748,345
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO salinomycin results in decreased expression of ALDH1 protein; salinomycin results in decreased expression of ALDH1A1 mRNA CTD PMID:25499043 PMID:30273566 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase decreases expression ISO salinomycin results in decreased expression of ALG2 mRNA CTD PMID:19682730 NCBI chr 5:63,187,466...63,192,025
Ensembl chr 5:63,187,468...63,192,025
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase decreases expression ISO salinomycin results in decreased expression of ALKBH1 mRNA CTD PMID:19682730 NCBI chr 6:111,456,096...111,476,829
Ensembl chr 6:111,456,187...111,477,090
JBrowse link
G Ammecr1 AMMECR nuclear protein 1 decreases expression ISO salinomycin results in decreased expression of AMMECR1 mRNA CTD PMID:19682730 NCBI chr  X:114,129,829...114,233,013
Ensembl chr  X:114,131,898...114,232,939
JBrowse link
G Ankrd13c ankyrin repeat domain 13C decreases expression ISO salinomycin results in decreased expression of ANKRD13C mRNA CTD PMID:19682730 NCBI chr 2:264,785,379...264,833,283
Ensembl chr 2:264,786,242...264,833,283
JBrowse link
G Anxa5 annexin A5 decreases expression ISO salinomycin results in decreased expression of ANXA5 mRNA CTD PMID:19682730 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Ar androgen receptor decreases expression ISO salinomycin results in decreased expression of AR mRNA; salinomycin results in decreased expression of AR protein CTD PMID:22215106 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 decreases expression ISO salinomycin results in decreased expression of ARAP1 mRNA CTD PMID:19682730 NCBI chr 1:166,459,062...166,525,200
Ensembl chr 1:166,478,005...166,525,255
JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression ISO salinomycin results in decreased expression of ARF3 mRNA CTD PMID:19682730 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 decreases expression ISO salinomycin results in decreased expression of ARPC5 mRNA CTD PMID:19682730 NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO salinomycin results in increased expression of ATF3 mRNA CTD PMID:22215106 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase decreases expression ISO salinomycin results in decreased expression of ATIC mRNA CTD PMID:19682730 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060
JBrowse link
G Atp13a3 ATPase 13A3 decreases expression ISO salinomycin results in decreased expression of ATP13A3 mRNA CTD PMID:19682730 NCBI chr11:73,936,750...73,963,852
Ensembl chr11:73,936,750...73,963,852
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression ISO salinomycin results in decreased expression of ATP1B3 mRNA CTD PMID:19682730 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO salinomycin results in decreased expression of ATXN3 mRNA CTD PMID:19682730 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bag6 BAG cochaperone 6 decreases expression ISO salinomycin results in decreased expression of BAG6 mRNA CTD PMID:19682730 NCBI chr20:5,124,512...5,138,084
Ensembl chr20:5,125,349...5,138,084
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO salinomycin results in decreased expression of BIRC5 protein CTD PMID:30273566 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Cald1 caldesmon 1 decreases expression ISO salinomycin results in decreased expression of CALD1 mRNA CTD PMID:19682730 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Casp3 caspase 3 increases cleavage ISO salinomycin results in increased cleavage of CASP3 protein CTD PMID:30273566 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 decreases expression ISO salinomycin results in decreased expression of CASP8 mRNA CTD PMID:19682730 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases cleavage ISO salinomycin results in increased cleavage of CASP9 protein CTD PMID:30273566 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccdc43 coiled-coil domain containing 43 decreases expression ISO salinomycin results in decreased expression of CCDC43 mRNA CTD PMID:19682730 NCBI chr10:90,644,993...90,658,241
Ensembl chr10:90,644,995...90,657,185
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO salinomycin results in decreased expression of CCL2 mRNA CTD PMID:19682730 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO salinomycin results in decreased expression of CCND2 mRNA CTD PMID:19682730 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccny cyclin Y decreases expression ISO salinomycin results in decreased expression of CCNY mRNA CTD PMID:19682730 NCBI chr17:62,332,537...62,462,644
Ensembl chr17:62,332,537...62,462,644
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO salinomycin results in decreased expression of CD44 protein CTD PMID:30273566 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdc123 cell division cycle 123 decreases expression ISO salinomycin results in decreased expression of CDC123 mRNA CTD PMID:19682730 NCBI chr17:76,410,629...76,454,275
Ensembl chr17:76,410,585...76,454,282
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein] CTD PMID:26896736 PMID:30273566 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30273566 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cep350 centrosomal protein 350 decreases expression ISO salinomycin results in decreased expression of CEP350 mRNA CTD PMID:19682730 NCBI chr13:73,499,715...73,637,707
Ensembl chr13:73,499,229...73,638,073
JBrowse link
G Clec11a C-type lectin domain containing 11A decreases expression ISO salinomycin results in decreased expression of CLEC11A mRNA CTD PMID:19682730 NCBI chr 1:100,290,374...100,293,515
Ensembl chr 1:100,289,295...100,293,558
JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO salinomycin results in decreased expression of CLIC1 mRNA CTD PMID:19682730 NCBI chr20:5,040,314...5,049,166
Ensembl chr20:5,040,337...5,049,166
JBrowse link
G Cltc clathrin heavy chain decreases expression ISO salinomycin results in decreased expression of CLTC mRNA CTD PMID:19682730 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266
JBrowse link
G Cnih4 cornichon family AMPA receptor auxiliary protein 4 decreases expression ISO salinomycin results in decreased expression of CNIH4 mRNA CTD PMID:19682730 NCBI chr13:99,469,382...99,490,693
Ensembl chr13:99,473,044...99,489,263
JBrowse link
G Cnot4 CCR4-NOT transcription complex, subunit 4 decreases expression ISO salinomycin results in decreased expression of CNOT4 mRNA CTD PMID:19682730 NCBI chr 4:62,561,443...62,663,225
Ensembl chr 4:62,561,444...62,663,200
JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO salinomycin results in decreased expression of COA7 mRNA CTD PMID:19682730 NCBI chr 5:127,925,726...127,936,516
Ensembl chr 5:127,925,726...127,936,509
JBrowse link
G Copb2 COPI coat complex subunit beta 2 decreases expression ISO salinomycin results in decreased expression of COPB2 mRNA CTD PMID:19682730 NCBI chr 8:106,582,339...106,603,763 JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression ISO salinomycin results in decreased expression of CSNK2A1 mRNA CTD PMID:19682730 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 decreases expression ISO salinomycin results in decreased expression of CSTF1 mRNA CTD PMID:19682730 NCBI chr 3:170,380,413...170,392,162
Ensembl chr 3:170,380,719...170,392,160
JBrowse link
G Ctbs chitobiase decreases expression ISO salinomycin results in decreased expression of CTBS mRNA CTD PMID:19682730 NCBI chr 2:252,305,874...252,320,387
Ensembl chr 2:252,305,874...252,320,387
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of CTNNB1 mRNA] CTD PMID:26896736 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO salinomycin results in decreased activity of CYP2D6 protein CTD PMID:26282489 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Dbr1 debranching RNA lariats 1 decreases expression ISO salinomycin results in decreased expression of DBR1 mRNA CTD PMID:19682730 NCBI chr 8:107,826,690...107,838,186
Ensembl chr 8:107,826,424...107,838,339
JBrowse link
G Dcaf7 DDB1 and CUL4 associated factor 7 decreases expression ISO salinomycin results in decreased expression of DCAF7 mRNA CTD PMID:19682730 NCBI chr10:94,231,585...94,254,046
Ensembl chr10:94,231,585...94,254,046
JBrowse link
G Dcbld1 discoidin, CUB and LCCL domain containing 1 decreases expression ISO salinomycin results in decreased expression of DCBLD1 mRNA CTD PMID:19682730 NCBI chr20:33,359,062...33,455,161
Ensembl chr20:33,359,196...33,453,766
JBrowse link
G Dcn decorin decreases expression ISO salinomycin results in decreased expression of DCN mRNA CTD PMID:19682730 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression ISO salinomycin results in decreased expression of DCUN1D4 mRNA CTD PMID:19682730 NCBI chr14:37,210,721...37,294,517
Ensembl chr14:37,210,721...37,294,472
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO salinomycin results in increased expression of DDIT3 mRNA CTD PMID:22215106 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO salinomycin results in increased expression of DDIT4 mRNA CTD PMID:22215106 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Desi2 desumoylating isopeptidase 2 decreases expression ISO salinomycin results in decreased expression of DESI2 mRNA CTD PMID:19682730 NCBI chr13:96,111,800...96,156,693
Ensembl chr13:96,111,800...96,154,685
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression ISO salinomycin results in decreased expression of DNAJC13 mRNA CTD PMID:19682730 NCBI chr 8:112,697,907...112,830,445
Ensembl chr 8:112,698,348...112,807,598
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO salinomycin results in decreased expression of DNMT3A mRNA CTD PMID:19682730 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dpf2 double PHD fingers 2 decreases expression ISO salinomycin results in decreased expression of DPF2 mRNA CTD PMID:19682730 NCBI chr 1:221,253,764...221,269,043
Ensembl chr 1:221,253,747...221,269,042
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO salinomycin results in decreased expression of DPYSL3 mRNA CTD PMID:19682730 NCBI chr18:37,716,371...37,819,347
Ensembl chr18:37,716,143...37,819,097
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 decreases expression ISO salinomycin results in decreased expression of DVL3 mRNA CTD PMID:19682730 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 decreases expression ISO salinomycin results in decreased expression of EIF4E2 mRNA CTD PMID:19682730 NCBI chr 9:94,310,476...94,325,445
Ensembl chr 9:94,307,852...94,336,831
JBrowse link
G Elp4 elongator acetyltransferase complex subunit 4 decreases expression ISO salinomycin results in decreased expression of ELP4 mRNA CTD PMID:19682730 NCBI chr 3:95,733,810...95,954,987 JBrowse link
G Emp3 epithelial membrane protein 3 decreases expression ISO salinomycin results in decreased expression of EMP3 mRNA CTD PMID:19682730 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G Eng endoglin decreases expression ISO salinomycin results in decreased expression of ENG protein CTD PMID:30273566 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Erg ETS transcription factor ERG decreases expression ISO salinomycin results in decreased expression of ERG mRNA CTD PMID:22215106 NCBI chr11:35,645,317...35,749,637
Ensembl chr11:35,646,116...35,749,594
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase decreases expression ISO salinomycin results in decreased expression of ETAA1 mRNA CTD PMID:19682730 NCBI chr14:102,290,655...102,293,674
Ensembl chr14:102,290,418...102,293,677
JBrowse link
G Ext1 exostosin glycosyltransferase 1 decreases expression ISO salinomycin results in decreased expression of EXT1 mRNA CTD PMID:19682730 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO salinomycin results in decreased expression of FGFR1 mRNA CTD PMID:19682730 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fhip2a FHF complex subunit HOOK interacting protein 2A decreases expression ISO salinomycin results in decreased expression of FHIP2A mRNA CTD PMID:19682730 NCBI chr 1:278,198,181...278,224,365
Ensembl chr 1:278,198,179...278,221,686
JBrowse link
G Fsd1l fibronectin type III and SPRY domain containing 1-like decreases expression ISO salinomycin results in decreased expression of FSD1L mRNA CTD PMID:19682730 NCBI chr 5:70,441,075...70,517,131
Ensembl chr 5:70,441,123...70,511,659
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression ISO salinomycin results in decreased expression of FTL mRNA CTD PMID:19682730 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO salinomycin results in decreased expression of FYN mRNA CTD PMID:19682730 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO salinomycin results in decreased expression of FZD2 mRNA CTD PMID:19682730 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO salinomycin results in decreased expression of GAP43 mRNA CTD PMID:19682730 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO salinomycin results in decreased expression of GAPDH mRNA CTD PMID:19682730 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gas6 growth arrest specific 6 decreases expression ISO salinomycin results in decreased expression of GAS6 mRNA CTD PMID:19682730 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Ghr growth hormone receptor decreases expression ISO salinomycin results in decreased expression of GHR mRNA CTD PMID:19682730 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression ISO salinomycin results in decreased expression of GLI1 mRNA; salinomycin results in decreased expression of GLI1 protein CTD PMID:25499043 PMID:30273566 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO salinomycin results in decreased expression of GNPDA1 mRNA CTD PMID:19682730 NCBI chr18:31,479,117...31,489,154
Ensembl chr18:31,479,117...31,487,671
JBrowse link
G Gorab golgin, RAB6-interacting decreases expression ISO salinomycin results in decreased expression of GORAB mRNA CTD PMID:19682730 NCBI chr13:81,682,207...81,698,827
Ensembl chr13:81,682,018...81,698,833
JBrowse link
G Gpc4 glypican 4 decreases expression ISO salinomycin results in decreased expression of GPC4 mRNA CTD PMID:19682730 NCBI chr  X:139,354,325...139,464,876
Ensembl chr  X:139,354,155...139,464,798
JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO salinomycin results in decreased expression of GPNMB mRNA CTD PMID:19682730 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO salinomycin results in decreased expression of GPRC5A mRNA CTD PMID:19682730 NCBI chr 4:168,832,937...168,851,650
Ensembl chr 4:168,832,910...168,851,652
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO salinomycin results in decreased expression of GSK3B mRNA CTD PMID:19682730 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gtf3c3 general transcription factor IIIC subunit 3 decreases expression ISO salinomycin results in decreased expression of GTF3C3 mRNA CTD PMID:19682730 NCBI chr 9:60,999,159...61,033,612
Ensembl chr 9:60,969,061...61,033,580
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [salinomycin results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO salinomycin results in decreased expression of HIF1A mRNA CTD PMID:19682730 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO salinomycin results in decreased expression of HS2ST1 mRNA CTD PMID:19682730 NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517
JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase decreases expression ISO salinomycin results in decreased expression of ICMT mRNA CTD PMID:19682730 NCBI chr 5:169,475,270...169,482,031
Ensembl chr 5:169,475,270...169,482,030
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO salinomycin binds to and results in decreased activity of IDO1 protein; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 mRNA]; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 protein] CTD PMID:32822738 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 decreases expression ISO salinomycin results in decreased expression of IDO2 protein CTD PMID:32822738 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Ifng interferon gamma multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased chemical synthesis of Kynurenine]; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 mRNA]; salinomycin inhibits the reaction [IFNG protein results in increased expression of IDO1 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK1 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK2 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of RELA protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:32822738 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression ISO salinomycin results in decreased expression of IGF2R mRNA CTD PMID:19682730 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO salinomycin results in decreased expression of IGFBP4 mRNA CTD PMID:19682730 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression ISO salinomycin results in decreased expression of IGFBP7 mRNA CTD PMID:19682730 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Ints2 integrator complex subunit 2 decreases expression ISO salinomycin results in decreased expression of INTS2 mRNA CTD PMID:19682730 NCBI chr10:73,632,805...73,690,952
Ensembl chr10:73,634,255...73,690,887
JBrowse link
G Ints8 integrator complex subunit 8 decreases expression ISO salinomycin results in decreased expression of INTS8 mRNA CTD PMID:19682730 NCBI chr 5:24,446,002...24,493,819
Ensembl chr 5:24,445,886...24,493,670
JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO salinomycin results in decreased expression of IRF9 mRNA CTD PMID:19682730 NCBI chr15:34,282,936...34,288,981
Ensembl chr15:34,282,936...34,288,138
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK1 protein] CTD PMID:32822738 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK2 protein] CTD PMID:32822738 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 decreases expression ISO salinomycin results in decreased expression of KDELR2 mRNA CTD PMID:19682730 NCBI chr12:13,192,452...13,210,758
Ensembl chr12:13,192,453...13,210,758
JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 decreases expression ISO salinomycin results in decreased expression of KDELR3 mRNA CTD PMID:19682730 NCBI chr 7:120,749,680...120,760,163
Ensembl chr 7:120,749,752...120,760,160
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO salinomycin results in increased expression of KLF6 mRNA CTD PMID:22215106 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Klhl20 kelch-like family member 20 decreases expression ISO salinomycin results in decreased expression of KLHL20 mRNA CTD PMID:19682730 NCBI chr13:78,912,361...78,957,226
Ensembl chr13:78,912,361...78,957,212
JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator decreases expression ISO salinomycin results in decreased expression of LARP1 mRNA CTD PMID:19682730 NCBI chr10:43,435,738...43,501,186
Ensembl chr10:43,446,526...43,498,066
JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO salinomycin results in decreased expression of LDHA mRNA CTD PMID:19682730 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lmbr1 limb development membrane protein 1 decreases expression ISO salinomycin results in decreased expression of LMBR1 mRNA CTD PMID:19682730 NCBI chr 4:2,116,094...2,274,111
Ensembl chr 4:2,116,094...2,201,749
JBrowse link
G Lpin2 lipin 2 decreases expression ISO salinomycin results in decreased expression of LPIN2 mRNA CTD PMID:19682730 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP mRNA]; [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP protein] CTD PMID:30796972 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO salinomycin results in decreased phosphorylation of MAPK1 protein CTD PMID:28395993 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression ISO salinomycin results in decreased expression of MAPK14 mRNA CTD PMID:19682730 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO salinomycin results in decreased phosphorylation of MAPK3 protein CTD PMID:28395993 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 decreases expression ISO salinomycin results in decreased expression of MARS1 mRNA CTD PMID:19682730 NCBI chr 7:70,585,011...70,602,425
Ensembl chr 7:70,585,013...70,602,310
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO salinomycin results in decreased expression of MMP10 mRNA CTD PMID:19682730 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression ISO salinomycin results in decreased expression of MMP14 mRNA CTD PMID:19682730 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases secretion
ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of MMP2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]
salinomycin results in decreased secretion of MMP2 protein
CTD PMID:26896736 PMID:28395993 PMID:30273566 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases secretion ISO salinomycin results in decreased secretion of MMP9 protein CTD PMID:28395993 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO salinomycin results in decreased expression of MT2A mRNA CTD PMID:19682730 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtrex Mtr4 exosome RNA helicase decreases expression ISO salinomycin results in decreased expression of MTREX mRNA CTD PMID:19682730 NCBI chr 2:44,726,716...44,787,013
Ensembl chr 2:44,717,781...44,786,963
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO salinomycin results in decreased expression of MYC mRNA CTD PMID:22215106 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myo10 myosin X decreases expression ISO salinomycin results in decreased expression of MYO10 mRNA CTD PMID:19682730 NCBI chr 2:77,868,398...78,072,443
Ensembl chr 2:77,868,412...78,071,309
JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO salinomycin results in decreased expression of NAT10 mRNA CTD PMID:19682730 NCBI chr 3:93,658,119...93,698,136
Ensembl chr 3:93,658,117...93,698,136
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO salinomycin results in increased expression of NFKBIA protein CTD PMID:32822738 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nid1 nidogen 1 decreases expression ISO salinomycin results in decreased expression of NID1 mRNA CTD PMID:19682730 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nid2 nidogen 2 decreases expression ISO salinomycin results in decreased expression of NID2 mRNA CTD PMID:19682730 NCBI chr15:4,893,999...4,951,893
Ensembl chr15:4,894,213...4,951,917
JBrowse link
G Nol8 nucleolar protein 8 decreases expression ISO salinomycin results in decreased expression of NOL8 mRNA CTD PMID:19682730 NCBI chr17:14,565,794...14,589,154
Ensembl chr17:14,565,794...14,589,154
Ensembl chr17:14,565,794...14,589,154
JBrowse link
G Notch3 notch receptor 3 decreases expression ISO salinomycin results in decreased expression of NOTCH3 mRNA CTD PMID:19682730 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO salinomycin results in decreased expression of NSF mRNA CTD PMID:19682730 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nuak2 NUAK family kinase 2 decreases expression ISO salinomycin results in decreased expression of NUAK2 mRNA CTD PMID:19682730 NCBI chr13:49,092,306...49,109,055
Ensembl chr13:49,092,306...49,109,050
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 decreases expression ISO salinomycin results in decreased expression of NUCKS1 mRNA CTD PMID:19682730 NCBI chr13:48,679,726...48,709,663
Ensembl chr13:48,679,774...48,705,575
JBrowse link
G Nudt5 nudix hydrolase 5 decreases expression ISO salinomycin results in decreased expression of NUDT5 mRNA CTD PMID:19682730 NCBI chr17:76,387,027...76,410,309
Ensembl chr17:76,387,031...76,410,294
JBrowse link
G Nup37 nucleoporin 37 decreases expression ISO salinomycin results in decreased expression of NUP37 mRNA CTD PMID:19682730 NCBI chr 7:28,715,299...28,750,978
Ensembl chr 7:28,701,690...28,743,326
JBrowse link
G Nup62 nucleoporin 62 decreases expression ISO salinomycin results in decreased expression of NUP62 mRNA CTD PMID:19682730 NCBI chr 1:100,811,140...100,827,119
Ensembl chr 1:100,811,755...100,827,111
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases expression ISO salinomycin results in decreased expression of PAK2 mRNA CTD PMID:19682730 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO salinomycin results in increased cleavage of PARP1 protein CTD PMID:30273566 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO salinomycin results in decreased expression of PDE8A mRNA CTD PMID:19682730 NCBI chr 1:143,036,083...143,160,395
Ensembl chr 1:143,036,218...143,159,433
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression ISO salinomycin results in decreased expression of PDGFRB mRNA CTD PMID:19682730 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO salinomycin results in decreased expression of PFKFB3 mRNA CTD PMID:19682730 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO salinomycin results in decreased expression of PGK1 mRNA CTD PMID:19682730 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel decreases expression ISO salinomycin results in decreased expression of PKD2 mRNA CTD PMID:19682730 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Plaa phospholipase A2, activating protein decreases expression ISO salinomycin results in decreased expression of PLAA mRNA CTD PMID:19682730 NCBI chr 5:113,548,913...113,578,928
Ensembl chr 5:113,548,913...113,578,928
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 decreases expression ISO salinomycin results in decreased expression of PLOD2 mRNA CTD PMID:19682730 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plp2 proteolipid protein 2 decreases expression ISO salinomycin results in decreased expression of PLP2 mRNA CTD PMID:19682730 NCBI chr  X:15,679,254...15,682,653
Ensembl chr  X:15,679,254...15,682,652
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing decreases expression ISO salinomycin results in decreased expression of PNKD mRNA CTD PMID:19682730 NCBI chr 9:81,566,074...81,634,531
Ensembl chr 9:81,566,074...81,634,534
JBrowse link
G Prepl prolyl endopeptidase-like decreases expression ISO salinomycin results in decreased expression of PREPL mRNA CTD PMID:19682730 NCBI chr 6:8,316,861...8,346,293
Ensembl chr 6:8,318,979...8,346,197
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression ISO salinomycin results in decreased expression of PSMA5 mRNA CTD PMID:19682730 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psmb7 proteasome 20S subunit beta 7 decreases expression ISO salinomycin results in decreased expression of PSMB7 mRNA CTD PMID:19682730 NCBI chr 3:22,890,072...22,951,718
Ensembl chr 3:22,871,105...22,952,063
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 decreases expression ISO salinomycin results in decreased expression of PSMD8 mRNA CTD PMID:19682730 NCBI chr 1:88,116,811...88,123,643
Ensembl chr 1:88,116,812...88,123,643
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases phosphorylation ISO salinomycin results in decreased phosphorylation of PTK2 protein CTD PMID:28395993 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptov1 PTOV1, extended AT-hook containing adaptor protein decreases expression ISO salinomycin results in decreased expression of PTOV1 mRNA CTD PMID:19682730 NCBI chr 1:100,859,346...100,866,917
Ensembl chr 1:100,859,349...100,865,894
JBrowse link
G Rab23 RAB23, member RAS oncogene family decreases expression ISO salinomycin results in decreased expression of RAB23 mRNA CTD PMID:19682730 NCBI chr 9:38,469,784...38,496,185
Ensembl chr 9:38,470,298...38,495,176
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO salinomycin results in decreased expression of RACK1 mRNA CTD PMID:19682730 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO salinomycin results in decreased expression of RAD23B mRNA CTD PMID:19682730 NCBI chr 5:72,103,704...72,141,701
Ensembl chr 5:72,103,704...72,141,700
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of RELA protein] CTD PMID:32822738 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1308147 similar to expressed sequence AW209491 decreases expression ISO salinomycin results in decreased expression of C7ORF25 mRNA CTD PMID:19682730 NCBI chr17:53,080,629...53,087,335
Ensembl chr17:53,080,638...53,087,274
JBrowse link
G RGD1311345 similar to CG9752-PA decreases expression ISO salinomycin results in decreased expression of C9ORF64 mRNA CTD PMID:19682730 NCBI chr17:6,683,152...6,690,724
Ensembl chr17:6,683,152...6,690,723
JBrowse link
G Rin2 Ras and Rab interactor 2 decreases expression ISO salinomycin results in decreased expression of RIN2 mRNA CTD PMID:19682730 NCBI chr 3:139,871,330...140,087,679
Ensembl chr 3:139,894,331...140,087,678
JBrowse link
G Rnf8 ring finger protein 8 decreases expression ISO salinomycin results in decreased expression of RNF8 mRNA CTD PMID:19682730 NCBI chr20:8,285,380...8,309,858
Ensembl chr20:8,285,296...8,309,908
JBrowse link
G Rybp RING1 and YY1 binding protein decreases expression ISO salinomycin results in decreased expression of RYBP mRNA CTD PMID:19682730 NCBI chr 4:132,689,623...132,740,823
Ensembl chr 4:132,689,531...132,740,938
JBrowse link
G Sdf4 stromal cell derived factor 4 decreases expression ISO salinomycin results in decreased expression of SDF4 mRNA CTD PMID:19682730 NCBI chr 5:173,425,922...173,444,478
Ensembl chr 5:173,425,907...173,444,620
JBrowse link
G Setd5 SET domain containing 5 decreases expression ISO salinomycin results in decreased expression of SETD5 mRNA CTD PMID:19682730 NCBI chr 4:145,017,549...145,095,247
Ensembl chr 4:145,017,608...145,095,245
JBrowse link
G Slc38a9 solute carrier family 38, member 9 decreases expression ISO salinomycin results in decreased expression of SLC38A9 mRNA CTD PMID:19682730 NCBI chr 2:44,512,556...44,592,793
Ensembl chr 2:44,512,895...44,592,053
JBrowse link
G Smg8 SMG8 nonsense mediated mRNA decay factor decreases expression ISO salinomycin results in decreased expression of SMG8 mRNA CTD PMID:19682730 NCBI chr10:74,379,224...74,388,838
Ensembl chr10:74,379,226...74,388,787
JBrowse link
G Smo smoothened, frizzled class receptor decreases expression ISO salinomycin results in decreased expression of SMO mRNA; salinomycin results in decreased expression of SMO protein CTD PMID:25499043 PMID:30273566 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 mRNA]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein] CTD PMID:26896736 PMID:30273566 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 decreases expression ISO salinomycin results in decreased expression of SNRNP25 mRNA CTD PMID:19682730 NCBI chr10:15,685,999...15,689,338
Ensembl chr10:15,686,008...15,689,325
JBrowse link
G Snx6 sorting nexin 6 decreases expression ISO salinomycin results in decreased expression of SNX6 mRNA CTD PMID:19682730 NCBI chr 6:75,626,927...75,670,172
Ensembl chr 6:75,626,927...75,670,135
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO salinomycin results in decreased expression of SOCS3 protein CTD PMID:32822738 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Spats2l spermatogenesis associated, serine-rich 2-like decreases expression ISO salinomycin results in decreased expression of SPATS2L mRNA CTD PMID:19682730 NCBI chr 9:64,643,223...64,843,963
Ensembl chr 9:64,643,281...64,843,960
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO salinomycin results in decreased expression of SPP1 mRNA CTD PMID:19682730 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srp54a signal recognition particle 54A decreases expression ISO salinomycin results in decreased expression of SRP54 mRNA CTD PMID:19682730 NCBI chr 6:75,996,629...76,035,768
Ensembl chr 6:75,996,643...76,034,083
JBrowse link
G Ssr1 signal sequence receptor subunit 1 decreases expression ISO salinomycin results in decreased expression of SSR1 mRNA CTD PMID:19682730 NCBI chr17:27,496,369...27,512,781
Ensembl chr17:27,492,220...27,523,912
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO salinomycin results in decreased expression of STAM mRNA CTD PMID:19682730 NCBI chr17:81,209,795...81,256,111
Ensembl chr17:81,209,867...81,255,808
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein] CTD PMID:32822738 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein] CTD PMID:32822738 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stau1 staufen double-stranded RNA binding protein 1 decreases expression ISO salinomycin results in decreased expression of STAU1 mRNA CTD PMID:19682730 NCBI chr 3:163,703,204...163,748,996
Ensembl chr 3:163,703,204...163,748,996
JBrowse link
G Stk39 serine threonine kinase 39 decreases expression ISO salinomycin results in decreased expression of STK39 mRNA CTD PMID:19682730 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of CTNNB1 mRNA]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of MMP2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 mRNA]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of and results in increased activity of SNAI1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein]; salinomycin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:26896736 PMID:30273566 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thumpd3 THUMP domain containing 3 decreases expression ISO salinomycin results in decreased expression of THUMPD3 mRNA CTD PMID:19682730 NCBI chr 4:144,985,850...145,010,164
Ensembl chr 4:144,985,880...145,008,831
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 decreases expression ISO salinomycin results in decreased expression of TICAM2 mRNA CTD PMID:19682730 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression ISO salinomycin results in decreased expression of TIMP3 mRNA CTD PMID:19682730 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tnc tenascin C decreases expression ISO salinomycin results in decreased expression of TNC mRNA CTD PMID:19682730 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO salinomycin results in decreased expression of TUBB3 mRNA CTD PMID:19682730 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO salinomycin results in decreased expression of TUBB mRNA CTD PMID:19682730 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Tymp thymidine phosphorylase decreases response to substance
increases expression
multiple interactions
ISO TYMP protein results in decreased susceptibility to salinomycin
salinomycin results in increased expression of TYMP mRNA; salinomycin results in increased expression of TYMP protein
[salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP mRNA]; [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP protein]; [tanespimycin co-treated with salinomycin] results in decreased expression of TYMP mRNA; acetylleucyl-leucyl-norleucinal inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]]; Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]; salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]; SB 203580 inhibits the reaction [salinomycin results in increased expression of TYMP mRNA]; SB 203580 promotes the reaction [[tanespimycin co-treated with salinomycin] results in decreased expression of TYMP mRNA]; tanespimycin inhibits the reaction [Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]]; tanespimycin inhibits the reaction [salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]]; tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP mRNA]; tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]
CTD PMID:30796972 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyw5 tRNA-yW synthesizing protein 5 decreases expression ISO salinomycin results in decreased expression of TYW5 mRNA CTD PMID:19682730 NCBI chr 9:64,077,841...64,096,265
Ensembl chr 9:64,077,845...64,096,265
JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression ISO salinomycin results in decreased expression of UBE2F mRNA CTD PMID:19682730 NCBI chr 9:98,394,112...98,428,684
Ensembl chr 9:98,398,128...98,428,128
JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S decreases expression ISO salinomycin results in decreased expression of UBE2S mRNA CTD PMID:19682730 NCBI chr 1:72,580,424...72,584,484
Ensembl chr 1:72,580,424...72,584,482
JBrowse link
G Uhrf1bp1 UHRF1 binding protein 1 decreases expression ISO salinomycin results in decreased expression of UHRF1BP1 mRNA CTD PMID:19682730 NCBI chr20:7,431,235...7,475,515
Ensembl chr20:7,431,355...7,471,900
JBrowse link
G Vim vimentin multiple interactions ISO salinomycin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:26896736 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vopp1 VOPP1 WW domain binding protein decreases expression ISO salinomycin results in decreased expression of VOPP1 mRNA CTD PMID:19682730 NCBI chr 4:88,441,067...88,515,141
Ensembl chr 4:88,441,067...88,515,138
JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 decreases expression ISO salinomycin results in decreased expression of WIPF1 mRNA CTD PMID:19682730 NCBI chr 3:60,150,001...60,207,125
Ensembl chr 3:60,150,021...60,166,013
JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 decreases expression ISO salinomycin results in decreased expression of XPNPEP1 mRNA CTD PMID:19682730 NCBI chr 1:273,708,217...273,758,247
Ensembl chr 1:273,708,212...273,758,442
JBrowse link
G Xpr1 xenotropic and polytropic retrovirus receptor 1 decreases expression ISO salinomycin results in decreased expression of XPR1 mRNA CTD PMID:19682730 NCBI chr13:72,918,552...73,056,785
Ensembl chr13:72,918,490...73,056,875
JBrowse link
G Yae1 YAE1 maturation factor of ABCE1 decreases expression ISO salinomycin results in decreased expression of YAE1 mRNA CTD PMID:19682730 NCBI chr17:49,610,548...49,617,065
Ensembl chr17:49,610,548...49,617,065
JBrowse link
G Zmat3 zinc finger, matrin type 3 decreases expression ISO salinomycin results in decreased expression of ZMAT3 mRNA CTD PMID:19682730 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator decreases expression ISO salinomycin results in decreased expression of ZYG11B mRNA CTD PMID:19682730 NCBI chr 5:127,844,062...127,878,792
Ensembl chr 5:127,847,129...127,878,792
JBrowse link
valinomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Valinomycin results in decreased activity of ABCB11 protein CTD PMID:12739759 PMID:20829430 PMID:23956101 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Casp3 caspase 3 increases cleavage
increases activity
ISO Valinomycin results in increased cleavage of CASP3 protein
Valinomycin results in increased activity of CASP3 protein
CTD PMID:18926839 PMID:28157593 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Valinomycin affects the localization of CYCS protein CTD PMID:19193189 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Valinomycin binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Valinomycin binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Nnat neuronatin decreases response to substance EXP NNAT protein results in decreased susceptibility to Valinomycin CTD PMID:12101027 NCBI chr 3:154,043,873...154,046,334
Ensembl chr 3:154,043,873...154,046,330
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions EXP Valinomycin inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents] CTD PMID:15860731 NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Valinomycin promotes the reaction [SLC18A2 protein results in increased uptake of Serotonin] CTD PMID:18287335 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Valinomycin binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      biological role 19726
        biophysical role 12686
          membrane transport modulator 12484
            ionophore 1193
              potassium ionophore 269
                Gramicidin A 0
                Salinomycin 199
                bafilomycin A1 70
                nigericin 9
                valinomycin 9
paths to the root