Gene: Chchd3 (coiled-coil-helix-coiled-coil-helix domain containing 3) Rattus norvegicus
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Symbol: Chchd3
Name: coiled-coil-helix-coiled-coil-helix domain containing 3
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); molecular adaptor activity (ortholog); phosphatase binding (ortholog); INVOLVED IN cristae formation (ortholog); inner mitochondrial membrane organization (ortholog); mitochondrial fusion (ortholog); PARTICIPATES IN mitochondrial protein import pathway; ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); substance-related disorder (ortholog); FOUND IN cytoplasm (ortholog); MICOS complex (ortholog); mitochondrial inner membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; acrylamide
AGR Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and phosphatase binding activity; predicted to be involved in cristae formation, mitochondrial fusion, and negative regulation of transcription by RNA polymerase II; predicted to localize to the MICOS complex and nucleus; orthologous to human CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3).
Merged Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and phosphatase binding activity; predicted to be involved in cristae formation, mitochondrial fusion, and negative regulation of transcription by RNA polymerase II; predicted to localize to the MICOS complex and nucleus; orthologous to human CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3); PARTICIPATES IN mitochondrial protein import pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; LOC296966; MICOS complex subunit MIC19
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0460,080,536 - 60,358,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0459,822,342 - 60,099,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4459,891,615 - 60,170,903 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1460,167,728 - 60,453,221 (-)NCBI
Celera456,445,848 - 56,700,814 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Chchd3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310325
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.