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Gene: Atp1a3 (ATPase Na+/K+ transporting subunit alpha 3) Rattus norvegicus
Symbol: Atp1a3
Name: ATPase Na+/K+ transporting subunit alpha 3
Description: Exhibits D1 dopamine receptor binding activity and amyloid-beta binding activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to retinoic acid; and monovalent inorganic cation transport. Localizes to several cellular components, including calyx of Held; dendritic spine; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in alternating hemiplegia of childhood; bipolar disorder; dystonia 12; and epilepsy. Orthologous to human ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
Also known as: Atpa1a3; ATPase Na+K+ transporting alpha 3 subunit; ATPase, Na+/K+ transporting, alpha 3 polypeptide; ATPase, Na+K+ transporting, alpha 3 subunit; na(+)/K(+) ATPase alpha(III) subunit; na(+)/K(+) ATPase alpha-3 subunit; Na+/K+ -ATPase alpha 3 subunit; NA,K-ATPase alpha subunit 3; sodium pump subunit alpha-3; sodium/potassium-transporting ATPase subunit alpha-3
Homo sapiens (human) : ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3)  HGNC  Alliance
Mus musculus (house mouse) : Atp1a3 (ATPase, Na+/K+ transporting, alpha 3 polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp1a3 (ATPase Na+/K+ transporting subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3)
Canis lupus familiaris (dog) : ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp1a3 (ATPase Na+/K+ transporting subunit alpha 3)
Sus scrofa (pig) : ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3)
Chlorocebus sabaeus (African green monkey) : ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3)
Heterocephalus glaber (naked mole-rat) : Atp1a3 (ATPase Na+/K+ transporting subunit alpha 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0181,852,423 - 81,881,565 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,852,429 - 81,881,549 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,104,725 - 83,133,845 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,280,714 - 80,309,834 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,358,824 - 80,387,945 (-)NCBI
Celera175,018,852 - 75,047,865 (-)NCBICelera
Cytogenetic Map1q21NCBI
RH 3.4 Map1842.5RGD
RH 2.0 Map1501.2RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp1a3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2169
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.